Civic Intelligence

Hereditary Disease Foundation

EIN 23-7376197 • 501(c)3 • New York, NY

View Organization Page

Profile

To fund innovative research towards curing huntington's disease and impacting other brain disorders.

601 West 168th Street 54New York, NY 10032

www.hdfoundation.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

36th percentile

0.08x

Higher debt load relative to assets than 36% of similar nonprofits.

501(c)3 • $10M-$25M nonprofits • Source year 2022

Liabilities / Revenue

57th percentile

0.31x

Higher debt load relative to revenue than 57% of similar nonprofits.

501(c)3 • $10M-$25M nonprofits • Source year 2022

Net Margin

86th percentile

42%

Higher net margin than 86% of similar nonprofits.

501(c)3 • $10M-$25M nonprofits • Source year 2022

Top Officer Pay

Score unavailable

No value available

No filing with officer rows is available for this organization yet.

Asset Growth

46th percentile

4.0%

Faster asset growth than 46% of similar nonprofits.

501(c)3 • $10M-$25M nonprofits • Annualized from 2020 to 2022

Revenue Growth

47th percentile

5.5%

Faster revenue growth than 47% of similar nonprofits.

501(c)3 • $10M-$25M nonprofits • Annualized from 2020 to 2022

Balance Sheet
Liabilities / Assets36th percentile

Assets

Up

$21,978,294

Up $3,743,986 (+21%) from 2023

Liabilities

Down

$2,828,419

Down $262,993 (-8.5%) from 2023

Net Assets

Up

$19,149,875

Up $4,006,979 (+26%) from 2023

Operations
Liabilities / Revenue57th percentileNet Margin86th percentile

Revenue

Up

$7,899,221

Up $5,320,380 (+206%) from 2023

Expenses

Down

$4,524,145

Down $214,490 (-4.5%) from 2023

Net Income

Up

$3,375,076

Up $5,534,870 (+256%) from 2023

Trend Graphs

Balance Sheet Trend

Asset Growth46th percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$30M$20M$10M$0Assets 2011: $9,436,673Liabilities 2011: $596,220Net Assets 2011: $8,840,4532011Assets 2014: $11,378,074Liabilities 2014: $600,178Net Assets 2014: $10,777,8962014Assets 2015: $11,110,344Liabilities 2015: $531,930Net Assets 2015: $10,578,4142015Assets 2016: $11,731,003Liabilities 2016: $565,743Net Assets 2016: $11,165,2602016Assets 2017: $11,878,583Liabilities 2017: $1,406,338Net Assets 2017: $10,472,2452017Assets 2018: $10,922,906Liabilities 2018: $844,715Net Assets 2018: $10,078,1912018Assets 2019: $12,457,716Liabilities 2019: $1,141,006Net Assets 2019: $11,316,7102019Assets 2020: $15,507,063Liabilities 2020: $1,781,608Net Assets 2020: $13,725,4552020Assets 2021: $18,145,612Liabilities 2021: $2,330,017Net Assets 2021: $15,815,5952021Assets 2022: $16,776,193Liabilities 2022: $1,380,514Net Assets 2022: $15,395,6792022Assets 2023: $18,234,308Liabilities 2023: $3,091,412Net Assets 2023: $15,142,8962023Assets 2024: $21,978,294Liabilities 2024: $2,828,419Net Assets 2024: $19,149,8752024

Highlighted filing

2024

Assets$21,978,294
Liabilities$2,828,419
Net Assets$19,149,875
Open 2024 Filing

Operations Trend

Revenue Growth47th percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$10M$5.0M$0-$5.0MExpenses 2011: $2,092,8612011Revenue 2014: $4,209,947Expenses 2014: $1,848,087Net Income 2014: $2,361,8602014Revenue 2015: $2,358,172Expenses 2015: $1,887,144Net Income 2015: $471,0282015Revenue 2016: $2,289,333Expenses 2016: $2,049,110Net Income 2016: $240,2232016Revenue 2017: $1,074,269Expenses 2017: $2,547,618Net Income 2017: -$1,473,3492017Revenue 2018: $2,691,357Expenses 2018: $2,137,659Net Income 2018: $553,6982018Revenue 2019: $2,027,985Expenses 2019: $2,301,831Net Income 2019: -$273,8462019Revenue 2020: $4,059,819Expenses 2020: $2,519,661Net Income 2020: $1,540,1582020Revenue 2021: $3,846,649Expenses 2021: $2,967,624Net Income 2021: $879,0252021Revenue 2022: $4,522,686Expenses 2022: $2,603,305Net Income 2022: $1,919,3812022Revenue 2023: $2,578,841Expenses 2023: $4,738,635Net Income 2023: -$2,159,7942023Revenue 2024: $7,899,221Expenses 2024: $4,524,145Net Income 2024: $3,375,0762024

Highlighted filing

2024

Revenue$7,899,221
Expenses$4,524,145
Net Income$3,375,076
Open 2024 Filing

Filings

Most recent year

2024 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$21,978,294
Liabilities
$2,828,419
Net assets
$19,149,875
Revenue
$7,899,221
Expenses
$4,524,145
Net income
$3,375,076
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$22.0$2.83$19.1$7.90$4.52$3.38
2023Detailed filing. Detailed filing data is available for this year.$18.2$3.09$15.1$2.58$4.74$2.16
2022Detailed filing. Detailed filing data is available for this year.$16.8$1.38$15.4$4.52$2.60$1.92
2021Detailed filing. Detailed filing data is available for this year.$18.1$2.33$15.8$3.85$2.97$0.88
2020Detailed filing. Detailed filing data is available for this year.$15.5$1.78$13.7$4.06$2.52$1.54
2019Detailed filing. Detailed filing data is available for this year.$12.5$1.14$11.3$2.03$2.30$0.27
2018Detailed filing. Detailed filing data is available for this year.$10.9$0.84$10.1$2.69$2.14$0.55
2017Detailed filing. Detailed filing data is available for this year.$11.9$1.41$10.5$1.07$2.55$1.47
2016Detailed filing. Detailed filing data is available for this year.$11.7$0.57$11.2$2.29$2.05$0.24
2015Detailed filing. Detailed filing data is available for this year.$11.1$0.53$10.6$2.36$1.89$0.47
2014Detailed filing. Detailed filing data is available for this year.$11.4$0.60$10.8$4.21$1.85$2.36
2011Facts available. Structured filing facts are available, but richer extracted sections are limited.$9.44$0.60$8.84$2.09
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
May 14, 2025
Return Version
2024v5.1
Gross Receipts
$14,021,176
Mission and Program Overview

Mission

To fund innovative research towards curing huntington's disease and impacting other brain disorders.

To fund transformative research to find treatments, and ultimately a cure, for huntington's disease.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$14,760,979$13,760,642▼ $1,000,337
Investments Other Securities-$5,137,263-
Savings and Temporary Cash Investments$1,085,556$1,654,084▲ $568,528
Pledges and Grants Receivable$1,756,404$986,607▼ $769,797
Cash and Non-Interest-Bearing Accounts$588,649$386,234▼ $202,415
Prepaid Expenses and Deferred Charges$37,315$50,271▲ $12,956
Total Assets$18,234,308$21,978,294▲ $3,743,986
Other Assets Total$5,405$3,193▼ $2,212
Liabilities
Grants Payable$2,968,806$2,791,613▼ $177,193
Other Liabilities$0$19,681▲ $19,681
Accounts Payable and Accrued Expenses$122,606$17,125▼ $105,481
Total Liabilities$3,091,412$2,828,419▼ $262,993
Net Assets / Fund Balance
Net Assets With Donor Restrictions$12,017,432$15,759,764▲ $3,742,332
Net Assets Without Donor Restrictions$3,125,464$3,390,111▲ $264,647
Total Net Assets Fund Balance$15,142,896$19,149,875▲ $4,006,979
Total Liabilities and Net Assets / Fund Balance$18,234,308$21,978,294▲ $3,743,986

Asset Categories

AssetBook ValueDepreciationBasis
Closely Held Equity Interests$5,137,263--

Endowment Activity

PeriodBeginningContrib.Gain/LossOther UsesEnd
2024$10,208,361-▲ $1,248,253$510,418$10,887,744
2023$8,982,275-▲ $1,732,681$449,114$10,208,361
2022$11,593,322-▼ $1,958,855$579,666$8,982,275
2021$10,244,052-▲ $1,932,598$512,203$11,593,322
2020$9,703,171-▲ $1,026,040$485,159$10,244,052
Compensation and Service Providers
Top Officer PayScore unavailable

Employees

NameTitleFull / Part TimeBaseOtherTotal
Sarah HernandezDirector of Research ProgramsFT$143,929$55,917$199,846
Julie PorterDirector of AdministrationFT$116,065$30,005$146,070
Meghan DonaldsonCEOFT$110,000-$110,000
Erica MatiszDirector of DevelopmentFT$108,500-$108,500
Tim KelleherCFOPT$42,765-$42,765
Karen NewmanChairPT$12,000-$12,000

Board Members and Trustees

NameTitle
Nancy S Wexler PhdPresident
Anne B Young Md PhdVice Chair
Berta a GehryDirector
C Frank Bennett PhdDirector
David Housman PhdDirector
David ZwallyDirector
Frank O GehryDirector
Joan Leiman PhdDirector
Lauren Baker PinkusDirector
Leslie M Thompson PhdDirector
Melissa MoserDirector
Robi BlumensteinDirector
Sandy FoxDirector
Tacie FoxDirector
Herbert Pardes MdDirector (through 4/24)
Alice Wexler PhdSecretary
Bruce DonaldsonTreasurer
Revenue and Support

Revenue Composition

Contributions and Grants
$6,573,281
Program Service Revenue
$0
Investment Income
$1,243,205
Other Revenue
$82,735
All Other Contributions
$6,246,084
Change in Net Assets
$3,375,076

Noncash Contribution Practices

Property subject to holding requirements
No
Reviewed unusual noncash gifts
No
Third parties used for noncash contributions
No

Noncash Contributions

Contribution TypeContribution CountReported AmountValuation Method
Secur Prtnrshp Trust Intrsts1$5,137,263Fair Market Value (FMV)
Securities Publicly Traded6$78,357Fair Market Value (FMV)
Total Noncash Contributions7$5,215,620-

Audited Revenue Reconciliation

Revenue per Audited Statements
$7,809,670
Revenue Not Reported on Financial Statements
$89,551
Revenue Not Reported on Form 990
$631,903
Total Revenue per Audited Statements
$8,441,573
Total Revenue per Form 990
$7,899,221
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$2,869,473
Other Expenses$1,000,193
Salaries, Compensation, and Employee Benefits$654,479
Total Fundraising Expense$294,843
Professional Fundraising Fees$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$2,121,165--$2,121,165
Foreign Grants$748,308--$748,308
Conferences and Meetings$417,369$3,703$14,039$435,111
Other Salaries and Wages$236,594$22,667$111,333$370,594
Fees for Services Other$135,345$19,646$56,931$211,922
Current Officers, Directors, Trustees, and Key Employees$55,000$87,765$22,000$164,765
Fees for Service Investment Mgmnt Fees-$89,551-$89,551
Other Employee Benefits$76,921$3,000$6,001$85,922
Fees for Services Accounting-$77,000-$77,000
Occupancy$23,905$4,563$19,171$47,639
Payroll Taxes$20,143$3,845$9,210$33,198
Other Expenses$24,809$5,548$2,662$33,019
Office Expenses$560$6,969$3,597$11,126
Insurance$4,282$818$1,958$7,058
Total Functional Expenses$3,899,500$329,802$294,843$4,524,145

Audited Expense Reconciliation

Line ItemAmount
Total Expenses per Form 990$4,524,145
Expenses per Audited Statements$4,434,594
Total Expenses per Audited Statements$4,434,594
Expenses Not Reported on Financial Statements$89,551
Expenses Not Reported on Form 990$0
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
Washington University School of Medicine in St LouisSaint Louis, MO501c3Scientific Research$1,104,000
Northwestern UniversityEvanston, IL501c3Scientific Research$200,000
The Board of Trustees of the Leland StanfRedwood City, CA501c3Scientific Research$175,672
CHILDREN'S HOSPITAL OF PHILADELPHIA THEPhiladelphia, PA501c3Scientific Research$100,000
Center for Genomic Medicine Massachusetts General HospitalBoston, MA501c3Scientific Research$100,000
Massachusetts Institute of TechnologyCambridge, MA501c3Scientific Research$100,000
Regents of the Univ of CA - San DiegoLa Jolla, CA501c3Scientific Research$100,000
Regents of the University of CA IrvineIrvine, CA501c3Scientific Research$100,000
The Regents Un of California -losangelesLos Angeles, CA501c3Scientific Research$100,000
Massachusetts Institute of TechnologyCambridge, MA501c3Scientific Research$30,000

International Summary

Offices
0
Employees
0
Spending
$748,308

International Compliance

Foreign grant records maintained
No
Activity in boycott countries
No
Foreign corporation ownership
No
Foreign partnership interest
No
Interest in foreign trust
No
Passive foreign investment company interest
No
Transfers to foreign corporations
No

International Activities

RegionActivityServicesOfficesEmployeesSpending
North America - Canada and Mexico, But Not the United StatesGrants to RecipientsScientific Research--$350,000
East Asia and the PacificGrants to RecipientsScientific Research--$199,892
Europe (including Iceland & Greenland) - Albania, Andorra, Austria, BelgiumGrants to RecipientsScientific Research--$198,416
Fundraising, Events, and Gaming
Fundraising activities
Yes
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Fundraising Direct Expenses$38,303
Fundraising Gross Income$38,303
Professional Fundraising Fees$0

Fundraising Events

EventGross ReceiptsGross RevenueDirect ExpensesNet Income
Hd Benefit$365,500$38,303$4,958$33,345
Total Events$365,500$38,303$38,303$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Funds Held for Others$19,681
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
No
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

“Nancy wexler, president, and alice wexler, secretary, are sisters and both are members of the board of directors. Meghan donaldson, ceo, and bruce donaldson, board member, are married and are both members of the board of directors. Frank gehry and berta gehry are married and both are members of the board of directors. Sandy fox is the aunt of david zwally and both are members of the board of directors. Tacie fox is the daughter of sandy fox and both are members of the board of directors.”

Form 990, Part VI, Section B, Line 11B

“The foundation provides the 990 to the board of directors for approval.”

Form 990, Part VI, Section B, Line 12C

“Annual conflict of interest statements are circulated to all officers, directors, and key employees at the board of directors meeting. Management maintains signed copies of these statements for all such individuals to ensure compliance with this policy.”

Form 990, Part VI, Section B, Line 15A

“A written employee contract is established and approved by the board or compensation committee.”

Form 990, Part VI, Section C, Line 19

“The foundation makes its financial statements and 990 available to the public on its website, www.hdfoundation.org. The foundation makes its governing documents and conflict of interest policy available to the public upon request.”

Form 990, Part VI, Line 13 and 14

“The organization had a draft whistleblower and document retention policy in place as of 12/31/24. The policies were formally approved by the board of directors prior to the 5/15/25 filing of the form 990.”

Filing and Contact Details

Filer

Filer Name
Hereditary Disease Foundation
EIN
23-7376197
Phone
2129282121
Address
601 WEST 168TH STREET 54, NEW YORK, NY 10032

Signing Officer

Name
Meghan Donaldson
Title
CEO
Phone
2129282121
Signed
2025-05-14
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Meghan Donaldson
Formed
1968
Legal Domicile
CA
Voting Board Members
18
Independent Board Members
16
Employees
4
Volunteers
50

Preparer

Firm
Sax Llp
Address
389 INTERPACE PARKWAY STE 3, PARSIPPANY, NJ 07054
Preparer
Marqus White
Phone
9734726250
Supplemental Narrative

Additional Explanations

FORM 990, PART XI, LINE 9:

“Write off of grants payable 75,000.”

Financial Statement Notes

PART X, LINE 2:

“Hdf does not believe its financial statements include any material, uncertain tax positions. Tax filings for the periods ending december 31, 2021 and later are subject to examination by applicable taxing authorities.”

PART XI, LINE 2D - OTHER ADJUSTMENTS:

“Write off of grants payable 75,000.”

Raw XML AppendixShowing 400 of 815 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/ActivityOrMissionDesc0TO FUND TRANSFORMATIVE RESEARCH TO FIND TREATMENTS, AND ULTIMATELY A CURE, FOR HUNTINGTON'S DISEASE.
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IRS990/Desc0THE HEREDITARY DISEASE FOUNDATION (HDF) ADVANCES PARADIGM-CHANGING HUNTINGTON'S DISEASE (HD) RESEARCH THROUGH A COLLABORATIVE APPROACH TO SCIENTIFIC DISCOVERY. WE INVEST IN RESEARCH BY PROVIDING SENIOR SCIENTISTS WITH GRANTS, INCLUDING OUR MILLION-DOLLAR TRANSFORMATIVE RESEARCH AWARDS, WHICH BEGAN IN 2023, AND FUNDING THE WORK OF EARLY CAREER SCIENTISTS THROUGH POSTDOCTORAL FELLOWSHIPS. WE CHAMPION COLLABORATIVE SCIENCE BY ORGANIZING BOTH SMALL THINKTANK-STYLE WORKSHOPS AND LARGE SCIENTIFIC CONFERENCES WHICH ENABLE EXPERTS IN HD TO SHARE THEIR LATEST DISCOVERIES, EXPLORE CUTTING-EDGE TECHNOLOGIES, AND FORM COLLABORATIONS. WE HIGHLIGHT FOR THE PUBLIC NOTABLE WORK OF SCIENTISTS THROUGH OUR WEBINARS.(CONTINUED ON SCHEDULE O)IN ITS EARLY YEARS, RESEARCH ORGANIZED AND FUNDED BY THE HDF WAS THE CATALYST FOR THE WORK THAT ISOLATED THE GENE THAT CAUSES HUNTINGTON'S DISEASE. THIS FINDING LED TO THE DEVELOPMENT OF A GENETIC TEST FOR HD AND LAUNCHED MODERN RESEARCH EFFORTS. THE HEREDITARY DISEASE FOUNDATION SUPPORTS RESEARCH THROUGH SEVERAL FUNDING OPPORTUNITIES.HDF RESEARCH GRANTS: ONE-YEAR GRANTS PROVIDE SENIOR RESEARCHERS WITH SEED FUNDING TO ENABLE THEM TO COLLECT THE PRELIMINARY DATA NEEDED TO OBTAIN MAJOR, LONG-TERM FUNDING FROM OTHER ORGANIZATIONS, INCLUDING THE NIH.HDF POSTDOCTORAL FELLOWSHIPS: TWO-YEAR FELLOWSHIPS FUND THE WORK OF EARLY-CAREER SCIENTISTS. THESE FELLOWSHIPS ARE INTENDED TO ENCOURAGE AND CULTIVATE INTEREST IN HUNTINGTON'S DISEASE RESEARCH.TRANSFORMATIVE RESEARCH AWARDS: THESE MILLION-DOLLAR RESEARCH AWARDS, HDF'S LARGEST GRANTS, FUND COLLABORATIVE RESEARCH TEAMS TO CREATE INNOVATIVE WAYS TO STUDY NEW PATHOGENIC DISEASE MECHANISMS AND TREATMENT MODALITIES IN HUNTINGTON'S DISEASE.HD CAREER ADVANCEMENT GRANTS: THESE ARE OUR NEWEST AWARDS WITH GRANTS BEGINNING IN 2025. THIS INCUBATOR PROGRAM SUPPORTS YOUNG INVESTIGATORS BY PROVIDING RESOURCES AND TOOLS TO BUILD THE NECESSARY SKILLS TO BRIDGE THE TRANSITION FROM POSTDOCTORAL POSITION TO TENURE-TRACK PRIMARY INVESTIGATOR. OUR GOAL THROUGH THIS PROGRAM AND OUR POSTDOCTORAL FELLOWSHIPS IS TO ENGAGE AND RETAIN THE BRIGHTEST MINDS IN HD RESEARCH BY FUNDING AND MENTORING EARLY-CAREER SCIENTISTS.HDF-FUNDED RESEARCHERS HAVE MADE SIGNIFICANT STRIDES IN APPLYING ADVANCED TECHNIQUES SUCH AS ARTIFICIAL INTELLIGENCE (AI), CRISPR AND BRAIN MAPPING, LEADING TO TREMENDOUS PROMISE FOR POTENTIAL TREATMENTS FOR HUNTINGTON'S DISEASE.
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IRS990/Form990PartVIISectionAGrp/TitleTxt1CHAIR
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IRS990/Form990PartVIISectionAGrp/TitleTxt6DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt7DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt8DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt9DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt10DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt11DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt12DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt13DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt14DIRECTOR (THROUGH 4/24)
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IRS990/Form990PartVIISectionAGrp/TitleTxt18DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt19CFO
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