Civic Intelligence

Prion Alliance Inc.

990 • Fiscal year 2020 • EIN 46-0732060

Jan 01, 2020 to Dec 31, 2020 • Filed on Mar 30, 2021

Organization Profileprionalliance.org
PO Box 391953Cambridge, MA 02139

(617) 714-8261

Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

55th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

2020 filings • 501(c)3 • <$500k nonprofits • Source year 2020

Liabilities / Revenue

55th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

2020 filings • 501(c)3 • <$500k nonprofits • Source year 2020

Net Margin

82nd percentile

36%

Higher net margin than 82% of similar nonprofits.

2020 filings • 501(c)3 • <$500k nonprofits • Source year 2020

Top Officer Pay

76th percentile

$0

Higher top officer pay than 76% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

2020 filings • 501(c)3 • <$500k nonprofits • Source year 2020

Asset Growth

76th percentile

38%

Faster asset growth than 76% of similar nonprofits.

2020 filings • 501(c)3 • <$500k nonprofits • Annualized from 2019 to 2020

Revenue Growth

34th percentile

-32%

Faster revenue growth than 34% of similar nonprofits.

2020 filings • 501(c)3 • <$500k nonprofits • Annualized from 2019 to 2020

Balance Sheet
Liabilities / Assets55th percentile

Assets

Up

$249,694

Up $68,902 (+38%) from 2019

Net Assets

Up

$249,694

Up $68,902 (+38%) from 2019

Liabilities

Flat

$0

Flat from 2019

Revenue And Expenses
Liabilities / Revenue55th percentileNet Margin82nd percentile

Revenue

Down

$190,882

Down $89,276 (-32%) from 2019

Expenses

Down

$121,980

Down $155,138 (-56%) from 2019

Net Income

Up

$68,902

Up $65,862 (+2167%) from 2019

Historical Trend

Balance Sheet Trend

Asset Growth76th percentile

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$800K$600K$400K$200K$0Assets 2017: $74,613Liabilities 2017: $0Net Assets 2017: $74,6132017Assets 2018: $177,751Liabilities 2018: $0Net Assets 2018: $177,7512018Assets 2019: $180,792Liabilities 2019: $0Net Assets 2019: $180,7922019Assets 2020: $249,694Liabilities 2020: $0Net Assets 2020: $249,6942020Assets 2021: $591,141Liabilities 2021: $0Net Assets 2021: $591,1412021Assets 2022: $412,041Liabilities 2022: $0Net Assets 2022: $412,0412022Assets 2023: $693,106Liabilities 2023: $9,429Net Assets 2023: $683,6772023Assets 2024: $417,060Liabilities 2024: $400Net Assets 2024: $416,6602024

Highlighted filing

2020

Assets$249,694
Liabilities$0
Net Assets$249,694
Open 2020 Filing

Operations Trend

Revenue Growth34th percentile

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$1.0M$500K$0-$500KRevenue 2017: $101,500Expenses 2017: $128,546Net Income 2017: -$27,0462017Revenue 2018: $247,110Expenses 2018: $143,972Net Income 2018: $103,1382018Revenue 2019: $280,158Expenses 2019: $277,118Net Income 2019: $3,0402019Revenue 2020: $190,882Expenses 2020: $121,980Net Income 2020: $68,9022020Revenue 2021: $535,617Expenses 2021: $194,170Net Income 2021: $341,4472021Revenue 2022: $245,129Expenses 2022: $424,229Net Income 2022: -$179,1002022Revenue 2023: $645,259Expenses 2023: $470,956Net Income 2023: $174,3032023Revenue 2024: $419,737Expenses 2024: $686,754Net Income 2024: -$267,0172024

Highlighted filing

2020

Revenue$190,882
Expenses$121,980
Net Income$68,902
Open 2020 Filing
Jump To
Filing Snapshot
Filing Period
Jan 1, 2020 to Dec 31, 2020
Signed
Mar 30, 2021
Return Version
2020v4.0
Gross Receipts
$190,882
Mission and Program Overview

Mission

Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.

Balance Sheet Detail
LineBeginningEndChange
Assets
Cash and Non-Interest-Bearing Accounts$180,792$249,694▲ $68,902
Savings and Temporary Cash Investments$0$0→ $0
Accounts Receivable$0$0→ $0
Other Notes and Loans Receivable, Net$0$0→ $0
Pledges and Grants Receivable$0$0→ $0
Receivable From Disqualified Prsn$0$0→ $0
Receivables From Officers Etc$0$0→ $0
Investments Other Securities$0$0→ $0
Investments Program Related$0$0→ $0
Investments in Publicly Traded Securities$0$0→ $0
Intangible Assets$0$0→ $0
Inventories for Sale or Use$0$0→ $0
Loans From Officers Directors$0$0→ $0
Prepaid Expenses and Deferred Charges$0$0→ $0
Total Assets$180,792$249,694▲ $68,902
Other Assets Total$0$0→ $0
Liabilities
Accounts Payable and Accrued Expenses$0$0→ $0
Grants Payable$0$0→ $0
Mortgage Notes Payable Secured by Investment Property$0$0→ $0
Unsecured Notes Loans Payable$0$0→ $0
Other Liabilities$0--
Deferred Revenue$0$0→ $0
Escrow Account Liability$0$0→ $0
Tax Exempt Bond Liabilities$0$0→ $0
Total Liabilities$0$0→ $0
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$180,792$249,694▲ $68,902
Net Assets With Donor Restrictions$0$0→ $0
Total Net Assets Fund Balance$180,792$249,694▲ $68,902
Total Liabilities and Net Assets / Fund Balance$180,792$249,694▲ $68,902
Compensation and Service Providers
Top Officer Pay76th percentile

Board Members and Trustees

NameTitle
Sonia VallabhPresident
Greta BeekhuisCo-director
Eric MinikelTreasurer
Revenue and Support

Revenue Composition

Contributions and Grants
$190,882
Program Service Revenue
$0
Investment Income
$0
Other Revenue
$0
All Other Contributions
$190,882
Change in Net Assets
$68,902
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$121,980
Other Expenses$0
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$121,980--$121,980
Total Functional Expenses$121,980$0$0$121,980
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Fundraising Direct Expenses$0
Fundraising Gross Income$0
Gaming Direct Expenses$0
Gaming Gross Income$0
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Loans from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Receivables from Disqualified Persons$0$0→ $0
Receivables from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
No
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

“Sonia Vallabh and Eric Minikel are married.”

Form 990, Part VI, Section B, Line 11B

“The form was filled out, saved as a draft, printed to PDF and emailed to directors for review.”

Form 990, Part VI, Section C, Line 19

“website, prionalliance.org”

Filing and Contact Details

Filer

Filer Name
Prion Alliance Inc
EIN
46-0732060
Phone
6177148261
Address
PO Box 391953, Cambridge, MA 02139

Signing Officer

Name
Eric Minikel
Title
Treasurer
Phone
6177148261
Signed
2021-03-30

Organization Details

Principal Officer
Eric Minikel
Formed
2012
Legal Domicile
Ma
Voting Board Members
3
Independent Board Members
3
Employees
0
Volunteers
3
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IRS990/ActivityOrMissionDesc0Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.
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IRS990/Desc0We maintained and characterized two transgenic mouse lines that our organization developed for the purposes of enabling discovery and development of human prion protein-lowering drugs.
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IRS990/MissionDesc0Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.
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IRS990/PrincipalOfficerNm0Eric Minikel
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IRS990/ProfessionalFundraisingInd00
IRS990/ProgSrvcAccomActy2Grp/Desc0We partnered with researchers at Utah State University to develop a new PRNP knockout hamster as a tool for PrP-lowering drug development.
IRS990/ProgSrvcAccomActy2Grp/ExpenseAmt020000
IRS990/ProgSrvcAccomActy2Grp/GrantAmt020000
IRS990/ProgSrvcAccomActy2Grp/RevenueAmt00
IRS990/ProgSrvcAccomActy3Grp/Desc0We initiated development of a new PRNP knockout rat model as a tool for PrP-lowering drug development.
IRS990/ProgSrvcAccomActy3Grp/ExpenseAmt012675
IRS990/ProgSrvcAccomActy3Grp/GrantAmt012675
IRS990/ProgSrvcAccomActy3Grp/RevenueAmt00
IRS990/ProgSrvcAccomActyOtherGrp/Desc0We undertook a variety of other efforts to support development of prion protein-lowering drugs.
IRS990/ProgSrvcAccomActyOtherGrp/ExpenseAmt021358
IRS990/ProgSrvcAccomActyOtherGrp/GrantAmt021358
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IRS990ScheduleA/PublicOrganization170Ind0X
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IRS990ScheduleA/PublicSupportPY170Pct00.70520
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Filings

Displayed year

2020 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$249,694
Liabilities
$0
Net assets
$249,694
Revenue
$190,882
Expenses
$121,980
Net income
$68,902
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$4.17$0.00$4.17$4.20$6.87$2.67
2023Detailed filing. Detailed filing data is available for this year.$6.93$0.09$6.84$6.45$4.71$1.74
2022Detailed filing. Detailed filing data is available for this year.$4.12$0.00$4.12$2.45$4.24$1.79
2021Detailed filing. Detailed filing data is available for this year.$5.91$0.00$5.91$5.36$1.94$3.41
2020Detailed filing. Detailed filing data is available for this year.$2.50$0.00$2.50$1.91$1.22$0.69
2019Detailed filing. Detailed filing data is available for this year.$1.81$0.00$1.81$2.80$2.77$0.03
2018Detailed filing. Detailed filing data is available for this year.$1.78$0.00$1.78$2.47$1.44$1.03
2017Detailed filing. Detailed filing data is available for this year.$0.75$0.00$0.75$1.02$1.29$0.27