Liabilities / Assets
56th percentile
Tied with the lowest-debt nonprofits in its peer group.
Siviq Scores
Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.
0.00x
Liabilities / Revenue
56th percentile
Tied with the lowest-debt nonprofits in its peer group.
Net Margin
13th percentile
Higher net margin than 13% of similar nonprofits.
Top Officer Pay
76th percentile
Higher top officer pay than 76% of similar nonprofits.
Top officer pay equals 0.0% of source-year revenue.
Asset Growth
Score unavailable
No earlier valid filing was available within the previous three public years.
Revenue Growth
Score unavailable
No earlier valid filing was available within the previous three public years.
Balance Sheet
Assets
$74,613
No earlier filing loaded for comparison.
Net Assets
$74,613
No earlier filing loaded for comparison.
Liabilities
$0
No earlier filing loaded for comparison.
Revenue And Expenses
Revenue
$101,500
No earlier filing loaded for comparison.
Expenses
$128,546
No earlier filing loaded for comparison.
Net Income
-$27,046
No earlier filing loaded for comparison.
Historical Trend
Jump To
Filing Snapshot
- Filing Period
- Jan 1, 2017 to Dec 31, 2017
- Signed
- Feb 18, 2018
- Return Version
- 2017v2.0
- Gross Receipts
- $101,500
Mission and Program Overview
Mission
Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.
Program Services
| Description | Grants | Expenses |
|---|---|---|
| We launched a clinical research study at Massachusetts General Hospital led by neurologist Dr. Steven Arnold. The study will bring healthy, pre-symptomatic prion protein gene mutation carriers and controls to Boston twice to donate cerebrospinal fluid as well as blood, and undergo a variety of cognitive and laboratory tests. The goal of the study is to establish biomarkers that can eventually be used in clinical trials of preventive drugs for prion disease. For more details see http://www.prionalliance.org/2017/07/19/prion-alliance-sponsors-mgh-research-study/ | $100,000 | $0 |
| We launched preclinical efficacy studies of antisense oligonucleotides against the prion protein gene as therapeutics for prion disease in conjunction with McLaughlin Research Institute in Great Falls, Montana. This study will help to establish proof-of-concept efficacy data to support the development of a human drug candidate against prion disease. | $10,710 | $0 |
| We undertook biomarker studies of cerebrospinal fluid from prion disease patients and controls to establish preliminary evidence supporting biomarkers that could be used in clinical trials of anti-prion drugs. The preliminary data from these studies (in the first half of 2017) informed our launch of the clinical research study at Massachusetts General Hospital later in 2017. These studies were supported in part by this gift from Prion Alliance to the Broad Institute | $10,000 | $0 |
Compensation and Service Providers
Employees
| Name | Title | Full / Part Time | Base | Other | Total |
|---|---|---|---|---|---|
| Eric Minikel | Treasurer | PT | $0 | - | - |
| Sonia Vallabh | President | PT | $0 | - | - |
| Greta Beekhuis | Co-Director | - | $0 | - | - |
Filing and Contact Details
Filer
- Filer Name
- Prion Alliance Inc
- EIN
- 46-0732060
- Phone
- 6177148261
- Address
- PO Box 391953, Cambridge, MA 02139
Signing Officer
- Name
- Eric Minikel
- Title
- Treasurer
- Phone
- 6177148261
- Signed
- 2018-02-18
Raw XML Appendix178 raw XML fields
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990EZ/PrimaryExemptPurposeTxt | 0 | Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration. |
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| ReturnHeader/BuildTS | 0 | 2018-06-14 16:35:46Z |
| ReturnHeader/BusinessOfficerGrp/PersonNm | 0 | Eric Minikel |
| ReturnHeader/BusinessOfficerGrp/PersonTitleTxt | 0 | Treasurer |
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| ReturnHeader/BusinessOfficerGrp/SignatureDt | 0 | 2018-02-18 |
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| ReturnHeader/ReturnTs | 0 | 2018-02-18T09:31:59-07:00 |
| ReturnHeader/ReturnTypeCd | 0 | 990EZ |
| ReturnHeader/TaxPeriodBeginDt | 0 | 2017-01-01 |
| ReturnHeader/TaxPeriodEndDt | 0 | 2017-12-31 |
| ReturnHeader/TaxYr | 0 | 2017 |
Document Assets
No mirrored PDF or thumbnail assets are attached yet.
Filings
Displayed year
2017 • Form 990EZDetailed filing. Detailed filing data is available for this year.
- Assets
- $74,613
- Liabilities
- $0
- Net assets
- $74,613
- Revenue
- $101,500
- Expenses
- $128,546
- Net income
- -$27,046