Civic Intelligence

Prion Alliance Inc.

990 • Fiscal year 2019 • EIN 46-0732060

Jan 01, 2019 to Dec 31, 2019 • Filed on Feb 17, 2020

Organization Profileprionalliance.org
PO Box 391953Cambridge, MA 02139

(617) 714-8261

Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

57th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

2019 filings • 501(c)3 • <$500k nonprofits • Source year 2019

Liabilities / Revenue

57th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

2019 filings • 501(c)3 • <$500k nonprofits • Source year 2019

Net Margin

44th percentile

1.1%

Higher net margin than 44% of similar nonprofits.

2019 filings • 501(c)3 • <$500k nonprofits • Source year 2019

Top Officer Pay

77th percentile

$0

Higher top officer pay than 77% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

2019 filings • 501(c)3 • <$500k nonprofits • Source year 2019

Asset Growth

49th percentile

1.7%

Faster asset growth than 49% of similar nonprofits.

2019 filings • 501(c)3 • <$500k nonprofits • Annualized from 2018 to 2019

Revenue Growth

66th percentile

13%

Faster revenue growth than 66% of similar nonprofits.

2019 filings • 501(c)3 • <$500k nonprofits • Annualized from 2018 to 2019

Balance Sheet
Liabilities / Assets57th percentile

Assets

Up

$180,792

Up $3,041 (+1.7%) from 2018

Net Assets

Up

$180,792

Up $3,041 (+1.7%) from 2018

Liabilities

Flat

$0

Flat from 2018

Revenue And Expenses
Liabilities / Revenue57th percentileNet Margin44th percentile

Revenue

Up

$280,158

Up $33,048 (+13%) from 2018

Expenses

Up

$277,118

Up $133,146 (+92%) from 2018

Net Income

Down

$3,040

Down $100,098 (-97%) from 2018

Historical Trend

Balance Sheet Trend

Asset Growth49th percentile

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$800K$600K$400K$200K$0Assets 2017: $74,613Liabilities 2017: $0Net Assets 2017: $74,6132017Assets 2018: $177,751Liabilities 2018: $0Net Assets 2018: $177,7512018Assets 2019: $180,792Liabilities 2019: $0Net Assets 2019: $180,7922019Assets 2020: $249,694Liabilities 2020: $0Net Assets 2020: $249,6942020Assets 2021: $591,141Liabilities 2021: $0Net Assets 2021: $591,1412021Assets 2022: $412,041Liabilities 2022: $0Net Assets 2022: $412,0412022Assets 2023: $693,106Liabilities 2023: $9,429Net Assets 2023: $683,6772023Assets 2024: $417,060Liabilities 2024: $400Net Assets 2024: $416,6602024

Highlighted filing

2019

Assets$180,792
Liabilities$0
Net Assets$180,792
Open 2019 Filing

Operations Trend

Revenue Growth66th percentile

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$1.0M$500K$0-$500KRevenue 2017: $101,500Expenses 2017: $128,546Net Income 2017: -$27,0462017Revenue 2018: $247,110Expenses 2018: $143,972Net Income 2018: $103,1382018Revenue 2019: $280,158Expenses 2019: $277,118Net Income 2019: $3,0402019Revenue 2020: $190,882Expenses 2020: $121,980Net Income 2020: $68,9022020Revenue 2021: $535,617Expenses 2021: $194,170Net Income 2021: $341,4472021Revenue 2022: $245,129Expenses 2022: $424,229Net Income 2022: -$179,1002022Revenue 2023: $645,259Expenses 2023: $470,956Net Income 2023: $174,3032023Revenue 2024: $419,737Expenses 2024: $686,754Net Income 2024: -$267,0172024

Highlighted filing

2019

Revenue$280,158
Expenses$277,118
Net Income$3,040
Open 2019 Filing
Jump To
Filing Snapshot
Filing Period
Jan 1, 2019 to Dec 31, 2019
Signed
Feb 17, 2020
Return Version
2019v5.0
Gross Receipts
$280,158
Mission and Program Overview

Mission

Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.

Balance Sheet Detail
LineBeginningEndChange
Assets
Cash and Non-Interest-Bearing Accounts$177,751$180,792▲ $3,041
Savings and Temporary Cash Investments$0$0→ $0
Accounts Receivable$0$0→ $0
Other Notes and Loans Receivable, Net$0$0→ $0
Pledges and Grants Receivable$0$0→ $0
Receivable From Disqualified Prsn$0$0→ $0
Receivables From Officers Etc$0$0→ $0
Investments Other Securities$0$0→ $0
Investments Program Related$0$0→ $0
Investments in Publicly Traded Securities$0$0→ $0
Land, Buildings, and Equipment, Net$0--
Intangible Assets$0$0→ $0
Inventories for Sale or Use$0$0→ $0
Loans From Officers Directors$0$0→ $0
Prepaid Expenses and Deferred Charges$0$0→ $0
Total Assets$177,751$180,792▲ $3,041
Other Assets Total$0$0→ $0
Liabilities
Accounts Payable and Accrued Expenses$0$0→ $0
Grants Payable$0$0→ $0
Mortgage Notes Payable Secured by Investment Property$0$0→ $0
Unsecured Notes Loans Payable$0$0→ $0
Other Liabilities$0--
Deferred Revenue$0$0→ $0
Escrow Account Liability$0$0→ $0
Tax Exempt Bond Liabilities$0$0→ $0
Total Liabilities$0$0→ $0
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$177,751$180,792▲ $3,041
Net Assets With Donor Restrictions$0$0→ $0
Total Net Assets Fund Balance$177,751$180,792▲ $3,041
Total Liabilities and Net Assets / Fund Balance$177,751$180,792▲ $3,041
Compensation and Service Providers
Top Officer Pay77th percentile

Board Members and Trustees

NameTitle
Sonia VallabhPresident
Greta BeekhuisCo-director
Eric MinikelTreasurer
Revenue and Support

Revenue Composition

Contributions and Grants
$280,158
Program Service Revenue
$0
Investment Income
$0
Other Revenue
$0
All Other Contributions
$280,158
Change in Net Assets
$3,040
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$277,118
Other Expenses$0
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$277,118--$277,118
Total Functional Expenses$277,118$0$0$277,118
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Fundraising Direct Expenses$0
Fundraising Gross Income$0
Gaming Direct Expenses$0
Gaming Gross Income$0
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Loans from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Receivables from Disqualified Persons$0$0→ $0
Receivables from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
No
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

“Sonia Vallabh and Eric Minikel are married.”

Form 990, Part VI, Section A, Line 8B

“There are no committees with authority to act on behalf of the governing body; all decisions are taken directly by the directors.”

Form 990, Part VI, Section B, Line 11B

“The form was filled out in draft by Treasurer Eric Minikel and circulated to the other directors for review before submission.”

Form 990, Part VI, Section C, Line 19

“Website (prionalliance.org)”

Filing and Contact Details

Filer

Filer Name
Prion Alliance Inc
EIN
46-0732060
Phone
6177148261
Address
PO Box 391953, Cambridge, MA 02139

Signing Officer

Name
Eric Minikel
Title
Treasurer
Phone
6177148261
Signed
2020-02-17

Organization Details

Principal Officer
Eric Minikel
Formed
2012
Legal Domicile
Ma
Voting Board Members
3
Independent Board Members
3
Employees
0
Volunteers
3
Supplemental Narrative

Additional Explanations

Form 990, Part XI, Line 9

“Correcting a rounding error.”

Raw XML AppendixShowing 400 of 523 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/ActivityOrMissionDesc0Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.
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IRS990/Desc0We supported efforts at the Broad Institute to develop prion protein-lowering therapeutics for prion disease, including preclinical efficacy studies and fluid biomarker studies. See the following publications for details: Vallabh et al, PMID: 30936307; Raymond et al, PMID: 31361599; Minikel & Kuhn et al, PMID: 31558565; Reidenbach & Minikel et al, PMID: 31861275; and Vallabh et al, DOI: https://doi.org/10.1101/2019.12.13.19014217
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IRS990/MissionDesc0Prion Alliance, Inc aims to catalyze the development of a treatment or cure for human prion diseases by funding, organizing and promoting scientific research. Our organization supports research directed at understanding prion disease biology, discovering and testing therapeutics, and developing novel lab and computational methodologies needed for furthering this research. Our operational model is to raise funds and disburse these to the most worthy scientific projects, with a view to the projects' relevance to our ultimate goal of a treatment or cure, as well as to the projects' ability to leverage Prion Alliance, Inc seed funding in order to pursue outside funding sources for continued research. We also strive to bring together top scientific minds to share data, methodology, and findings in a spirit of openness and collaboration.
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IRS990/PrincipalOfficerNm0Eric Minikel
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IRS990/ProgSrvcAccomActy2Grp/Desc0We continued to work with Cambridge Biomedical (now Bioagilytix) to develop a quantitative assay for cross-species prion protein quantification as a tool for preclinical and clinical development of prion protein-lowering drugs.
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Filings

Displayed year

2019 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$180,792
Liabilities
$0
Net assets
$180,792
Revenue
$280,158
Expenses
$277,118
Net income
$3,040
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$4.17$0.00$4.17$4.20$6.87$2.67
2023Detailed filing. Detailed filing data is available for this year.$6.93$0.09$6.84$6.45$4.71$1.74
2022Detailed filing. Detailed filing data is available for this year.$4.12$0.00$4.12$2.45$4.24$1.79
2021Detailed filing. Detailed filing data is available for this year.$5.91$0.00$5.91$5.36$1.94$3.41
2020Detailed filing. Detailed filing data is available for this year.$2.50$0.00$2.50$1.91$1.22$0.69
2019Detailed filing. Detailed filing data is available for this year.$1.81$0.00$1.81$2.80$2.77$0.03
2018Detailed filing. Detailed filing data is available for this year.$1.78$0.00$1.78$2.47$1.44$1.03
2017Detailed filing. Detailed filing data is available for this year.$0.75$0.00$0.75$1.02$1.29$0.27