Liabilities / Assets
Score unavailable
Liabilities-to-assets requires both liabilities and assets on this filing.
990 • Fiscal year 2010 • EIN 35-2023710
Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.
Liabilities / Assets
Score unavailable
Liabilities-to-assets requires both liabilities and assets on this filing.
Liabilities / Revenue
Score unavailable
Liabilities-to-revenue requires both liabilities and revenue on this filing.
Net Margin
Score unavailable
Net margin requires both revenue and expenses on this filing.
Top Officer Pay
Score unavailable
This filing does not contain officer compensation rows.
Asset Growth
Score unavailable
No earlier valid filing was available within the previous three public years.
Revenue Growth
Score unavailable
No valid filing value is available for this score.
Assets
$0
No earlier filing loaded for comparison.
Net Assets
$0
No earlier filing loaded for comparison.
Liabilities
$0
No earlier filing loaded for comparison.
Revenue
-
No earlier filing loaded for comparison.
Expenses
$4,551,556
No earlier filing loaded for comparison.
Net Income
-
No earlier filing loaded for comparison.
Engage primarily in the continuous active conduct of medical research and in general to engage in, promote and support the advancement of medical and surgical science.
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990/ActivityOrMissionDescription | 0 | TO ENGAGE IN THE CONTINUOUS ACTIVE CONDUCT OF CLINICAL AND TRANSITIONAL BIOMEDICAL RESEARCH. |
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| IRS990/Description | 0 | PLANNED PROGRAMS AND CORPORATE SUPPORT FUNCTIONS Methodist Research Institute's focus is clinical and transitional biomedical research. Current "cutting edge" research project areas include: - Cellular Biochemistry & Nutrition - Cryobiology - Education - Experimental Pathology of Cardiovascular Disease - Neuroscience - Non- & Minimally-Invasive Surgical Techniques - Oncology - Outcomes Research - Trauma Protocols Necessary to these research efforts are the Clinical Research Nurses who manage, monitor, and counsel patients in drug and device clinical research trials for Cardiovascular Disease, Diabetes, Infectious Disease, Renal disease, Oncology, Organ Transplantation, Radiology, Respiratory Disease, and Pain Management. Also integral to all research is the on-site Animal Laboratory, unique to the region, supporting clinical research and surgical practices by providing laboratory space, equipment, animals, certified technicians, and training. Methodist Research Insititute, Inc. ("MRI") works together with its parent company Indiana University Health, Inc. ("IU Health") and related hospital facility under IU Health, Indiana Health Methodist Hospital. Corporate support functions include secretarial staff, biostatistical support, data services, account and grant management functions, medical writing support, and executive management. Cellular Biochemistry & Nutrition The Cellular Biochemistry Research Laboratory continues to study dietary additives and their beneficial effects on human health. It has been determined that nutrient treatments affect adhesion, migration, and proliferation of breast cancer cells. Studies focused on investigating how Omega-3 polyunsaturated fatty acids modulate cellular activities, which then leads to their beneficial effects on the cardiovascular system and their preventive effects on cancer were done in 2010. Current Research - DHA + Curcumin breast cancer research: We were awarded a two year NIH-RO3 for studying the synergistic anticancer effects of DHA and Curcumin in Breast Cancer. The preliminary studies indicate DHA + Curcumin induce synergistic anticancer effects in a SKBR3 breast cancer (Estrogen receptor-negative, Her-positive) cell line. Our whole genome wide micro-array analysis suggests that synergistic effects of DHA and curcumin to regulate cellular events that involved in both initiation and progression of breast cancer growth. At present we are about to start animal studies to further validate our findings in cell culture studies. - Fatty acid regulation of endothelial activation: Investigating how fatty acids modulate endothelial cell activation in vitro. The data collected during almost 3 years of research was used for ten presentations. Three manuscripts are published (J Clinical Nutrition, J Lipid Research, Lipids) and currently two additional manuscripts are under preparation for publication. - Effect of nutritional compounds on muscle protein synthesis/degradation: The Cellular Biochemistry Laboratory has investigated the effects of nutritional compounds on protein synthesis/degradation in myocytes. - Effect of DHA on niacin-induced flushing: This project investigates the effects of omega-3 fatty acids on niacin-induced prostaglandin production. One publication is under preparation and we anticipate offering a presentation from this work to the American Heart Association in 2011. Cryobiology The Cryobiology Research Laboratory investigates aspects of cryobiology and hypothermia. Transplantation is made possible by applying techniques to slow the progression of injury when there is a lack of blood flow and oxygen to cells, tissues, or organs. Simple strategies such as cryopreservation are successfully applied to isolated cells but are destructive to tissues and organs that have complex structure-function relationships. In these cases, hypothermia is used to slow the metabolic demand for oxygen and reduce ischemic injury. However, hypothermia disturbs homeostatic processes and as |
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| IRS990/MissionDescription | 0 | TO ENGAGE PRIMARILY IN THE CONTINUOUS ACTIVE CONDUCT OF MEDICAL RESEARCH, INCLUDING BASIC AND CLINICAL INVESTIGATIONS, EXPERIMENTS AND STUDIES TO DISCOVER, DEVELOP OR VERIFY KNOWLEDGE RELATING TO THE CAUSES, DIAGNOSIS, TREATMENT, PREVENTION OR CONTROL OF PHYSICAL OR MENTAL DISEASES OR IMPAIRMENTS OF MAN, AND IN GENERAL TO ENGAGE IN, PROMOTE AND SUPPORT THE ADVANCEMENT OF MEDICAL AND SURGICAL SCIENCE THROUGH ALL PROPER AND LEGITIMATE AGENCIES AND MEANS. |
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| IRS990ScheduleJ/Form990ScheduleJPartII/DeferredCompFilingOrg | 6 | 0 |
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| IRS990ScheduleJ/Form990ScheduleJPartII/DeferredCompRelatedOrgs | 6 | 92653 |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation | 0 | Methodist Research Institute, Inc. relied on Indiana University Health, Inc. to determine the compensation of the CEO. Indiana University Health, Inc., a 501(c)(3) tax-exempt hospital, uses a compensation committee, independent compensation consultant, written employee contract, compensation survey or study, and approval by the board or compensation committee to establish compensation. |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation | 1 | John Kohne, M.D. participates in an Indiana University Health, Inc. supplemental retirement plan, provisions of which are designed to retain critical employees. Included in Part II, column c, deferred compensation, is an amount that represents the current year increase in the accrued benefit and/or current year deposits. No amount was actually paid to the executive during the year. The plan provides for an additional retirement benefit for service through normal retirement or other key dates. If the executive leaves prior to retirement or other key dates, the benefit may be forfeited or reduced. |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation | 2 | Amounts disclosed in Column B(ii) include a long-term and short-term incentive for certain executives and short-term incentive for other employees. Although these plans are based on a fixed formula that has been approved by the Indiana University Health, Inc. Board of Directors based upon certain qualitative and quantitative factors and goals, all discretionary incentive plans must be approved by the Indiana University Health, Inc. Committee on Personnel and Compensation and Board of Directors prior to any incentive payout. |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation | 3 | Compensation paid by related parties represents amounts which are reimbursed to Indiana University School of Medicine by Indiana University Health, Inc. to cover a portion of Dr. Williams' salary. |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier | 0 | SCHEDULE J, PART I |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier | 1 | SCHEDULE J, PART I |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier | 2 | Schedule J, Part I |
| IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier | 3 | Schedule J, Part II |
| IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference | 0 | Line 3 - Establishment of CEO/Executive Director Compensation |
| IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference | 1 | LINE 4B - SUPPLEMENTAL NONQUALIFIED RETIREMENT PLAN |
| IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference | 2 | Line 7 - Non-fixed Payments |
| IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference | 3 | COMPENSATION - ERIC WILLIAMS, M.D. |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 0 | JAMES E LINGEMAN MD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 1 | KEITH MARCH MD PHD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 2 | JOHN BLACK MD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 3 | ERIC WILLIAMS MD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 4 | ART COFFEY MD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 5 | CARY N MARIASH MD |
| IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson | 6 | JOHN KOHNE MD |
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| IRS990ScheduleJ/Form990ScheduleJPartII/NontaxableBenefitsRelatedOrgs | 3 | 112 |
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| IRS990ScheduleJ/Form990ScheduleJPartII/NontaxableBenefitsRelatedOrgs | 5 | 0 |
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| IRS990ScheduleJ/Form990ScheduleJPartII/OtherCompensationFilingOrg | 5 | 2772 |
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Displayed year
2010 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.
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