Civic Intelligence

Methodist Research Institute Inc

990 • Fiscal year 2010 • EIN 35-2023710

Jan 01, 2010 to Dec 31, 2010 • Filed on Nov 15, 2011

950 N Meridian Street Suite 80046204
Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

Score unavailable

No value available

Liabilities-to-assets requires both liabilities and assets on this filing.

Source year 2010

Liabilities / Revenue

Score unavailable

No value available

Liabilities-to-revenue requires both liabilities and revenue on this filing.

Source year 2010

Net Margin

Score unavailable

No value available

Net margin requires both revenue and expenses on this filing.

Source year 2010

Top Officer Pay

Score unavailable

No value available

This filing does not contain officer compensation rows.

Source year 2010

Asset Growth

Score unavailable

No value available

No earlier valid filing was available within the previous three public years.

Source year 2010

Revenue Growth

Score unavailable

No value available

No valid filing value is available for this score.

Assets

$0

No earlier filing loaded for comparison.

Net Assets

$0

No earlier filing loaded for comparison.

Liabilities

$0

No earlier filing loaded for comparison.

Revenue

-

No earlier filing loaded for comparison.

Expenses

$4,551,556

No earlier filing loaded for comparison.

Net Income

-

No earlier filing loaded for comparison.

Historical Trend

Balance Sheet Trend

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$0Assets 2010: $0Liabilities 2010: $0Net Assets 2010: $02010Assets 2011: $0Liabilities 2011: $0Net Assets 2011: $02011Assets 2012: $0Liabilities 2012: $0Net Assets 2012: $02012Assets 2013: $0Liabilities 2013: $0Net Assets 2013: $02013Assets 2014: $0Liabilities 2014: $0Net Assets 2014: $02014Assets 2015: $0Liabilities 2015: $0Net Assets 2015: $02015Assets 2016: $0Liabilities 2016: $0Net Assets 2016: $02016Assets 2017: $0Liabilities 2017: $0Net Assets 2017: $02017

Highlighted filing

2010

Assets$0
Liabilities$0
Net Assets$0

Operations Trend

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$6.0M$4.0M$2.0M$0Expenses 2010: $4,551,5562010Expenses 2011: $4,451,3662011Expenses 2012: $3,965,4592012Revenue 2013: $3,954,406Expenses 2013: $3,954,406Net Income 2013: $02013Revenue 2014: $3,879,729Expenses 2014: $3,879,729Net Income 2014: $02014Revenue 2015: $2,828,251Expenses 2015: $2,828,251Net Income 2015: $02015Revenue 2016: $2,568,120Expenses 2016: $2,568,120Net Income 2016: $02016Revenue 2017: $2,707,760Expenses 2017: $2,707,760Net Income 2017: $02017

Highlighted filing

2010

Revenue-
Expenses$4,551,556
Net Income-
Jump To
Filing Snapshot
Filing Period
Jan 1, 2010 to Dec 31, 2010
Signed
Nov 15, 2011
Return Version
2010v3.4
Gross Receipts
$4,551,556
Mission and Program Overview

Mission

Engage primarily in the continuous active conduct of medical research and in general to engage in, promote and support the advancement of medical and surgical science.

Filing and Contact Details

Filer

EIN
35-2023710
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IRS990/Description0PLANNED PROGRAMS AND CORPORATE SUPPORT FUNCTIONS Methodist Research Institute's focus is clinical and transitional biomedical research. Current "cutting edge" research project areas include: - Cellular Biochemistry & Nutrition - Cryobiology - Education - Experimental Pathology of Cardiovascular Disease - Neuroscience - Non- & Minimally-Invasive Surgical Techniques - Oncology - Outcomes Research - Trauma Protocols Necessary to these research efforts are the Clinical Research Nurses who manage, monitor, and counsel patients in drug and device clinical research trials for Cardiovascular Disease, Diabetes, Infectious Disease, Renal disease, Oncology, Organ Transplantation, Radiology, Respiratory Disease, and Pain Management. Also integral to all research is the on-site Animal Laboratory, unique to the region, supporting clinical research and surgical practices by providing laboratory space, equipment, animals, certified technicians, and training. Methodist Research Insititute, Inc. ("MRI") works together with its parent company Indiana University Health, Inc. ("IU Health") and related hospital facility under IU Health, Indiana Health Methodist Hospital. Corporate support functions include secretarial staff, biostatistical support, data services, account and grant management functions, medical writing support, and executive management. Cellular Biochemistry & Nutrition The Cellular Biochemistry Research Laboratory continues to study dietary additives and their beneficial effects on human health. It has been determined that nutrient treatments affect adhesion, migration, and proliferation of breast cancer cells. Studies focused on investigating how Omega-3 polyunsaturated fatty acids modulate cellular activities, which then leads to their beneficial effects on the cardiovascular system and their preventive effects on cancer were done in 2010. Current Research - DHA + Curcumin breast cancer research: We were awarded a two year NIH-RO3 for studying the synergistic anticancer effects of DHA and Curcumin in Breast Cancer. The preliminary studies indicate DHA + Curcumin induce synergistic anticancer effects in a SKBR3 breast cancer (Estrogen receptor-negative, Her-positive) cell line. Our whole genome wide micro-array analysis suggests that synergistic effects of DHA and curcumin to regulate cellular events that involved in both initiation and progression of breast cancer growth. At present we are about to start animal studies to further validate our findings in cell culture studies. - Fatty acid regulation of endothelial activation: Investigating how fatty acids modulate endothelial cell activation in vitro. The data collected during almost 3 years of research was used for ten presentations. Three manuscripts are published (J Clinical Nutrition, J Lipid Research, Lipids) and currently two additional manuscripts are under preparation for publication. - Effect of nutritional compounds on muscle protein synthesis/degradation: The Cellular Biochemistry Laboratory has investigated the effects of nutritional compounds on protein synthesis/degradation in myocytes. - Effect of DHA on niacin-induced flushing: This project investigates the effects of omega-3 fatty acids on niacin-induced prostaglandin production. One publication is under preparation and we anticipate offering a presentation from this work to the American Heart Association in 2011. Cryobiology The Cryobiology Research Laboratory investigates aspects of cryobiology and hypothermia. Transplantation is made possible by applying techniques to slow the progression of injury when there is a lack of blood flow and oxygen to cells, tissues, or organs. Simple strategies such as cryopreservation are successfully applied to isolated cells but are destructive to tissues and organs that have complex structure-function relationships. In these cases, hypothermia is used to slow the metabolic demand for oxygen and reduce ischemic injury. However, hypothermia disturbs homeostatic processes and as
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IRS990/MissionDescription0TO ENGAGE PRIMARILY IN THE CONTINUOUS ACTIVE CONDUCT OF MEDICAL RESEARCH, INCLUDING BASIC AND CLINICAL INVESTIGATIONS, EXPERIMENTS AND STUDIES TO DISCOVER, DEVELOP OR VERIFY KNOWLEDGE RELATING TO THE CAUSES, DIAGNOSIS, TREATMENT, PREVENTION OR CONTROL OF PHYSICAL OR MENTAL DISEASES OR IMPAIRMENTS OF MAN, AND IN GENERAL TO ENGAGE IN, PROMOTE AND SUPPORT THE ADVANCEMENT OF MEDICAL AND SURGICAL SCIENCE THROUGH ALL PROPER AND LEGITIMATE AGENCIES AND MEANS.
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IRS990ScheduleA/GeneralExplanation0Methodist Research Institute, Inc. supports Indiana University Health, Inc's primary exempt purpose by performing cutting edge clinical research to ensure Indiana University Health, Inc. can continue to improve the health of patients and communities through innovatoin and excellence in care, education, research and service.
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IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation0Methodist Research Institute, Inc. relied on Indiana University Health, Inc. to determine the compensation of the CEO. Indiana University Health, Inc., a 501(c)(3) tax-exempt hospital, uses a compensation committee, independent compensation consultant, written employee contract, compensation survey or study, and approval by the board or compensation committee to establish compensation.
IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation1John Kohne, M.D. participates in an Indiana University Health, Inc. supplemental retirement plan, provisions of which are designed to retain critical employees. Included in Part II, column c, deferred compensation, is an amount that represents the current year increase in the accrued benefit and/or current year deposits. No amount was actually paid to the executive during the year. The plan provides for an additional retirement benefit for service through normal retirement or other key dates. If the executive leaves prior to retirement or other key dates, the benefit may be forfeited or reduced.
IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation2Amounts disclosed in Column B(ii) include a long-term and short-term incentive for certain executives and short-term incentive for other employees. Although these plans are based on a fixed formula that has been approved by the Indiana University Health, Inc. Board of Directors based upon certain qualitative and quantitative factors and goals, all discretionary incentive plans must be approved by the Indiana University Health, Inc. Committee on Personnel and Compensation and Board of Directors prior to any incentive payout.
IRS990ScheduleJ/Form990ScheduleJPartIII/Explanation3Compensation paid by related parties represents amounts which are reimbursed to Indiana University School of Medicine by Indiana University Health, Inc. to cover a portion of Dr. Williams' salary.
IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier0SCHEDULE J, PART I
IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier1SCHEDULE J, PART I
IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier2Schedule J, Part I
IRS990ScheduleJ/Form990ScheduleJPartIII/Identifier3Schedule J, Part II
IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference0Line 3 - Establishment of CEO/Executive Director Compensation
IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference1LINE 4B - SUPPLEMENTAL NONQUALIFIED RETIREMENT PLAN
IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference2Line 7 - Non-fixed Payments
IRS990ScheduleJ/Form990ScheduleJPartIII/ReturnReference3COMPENSATION - ERIC WILLIAMS, M.D.
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson0JAMES E LINGEMAN MD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson1KEITH MARCH MD PHD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson2JOHN BLACK MD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson3ERIC WILLIAMS MD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson4ART COFFEY MD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson5CARY N MARIASH MD
IRS990ScheduleJ/Form990ScheduleJPartII/NamePerson6JOHN KOHNE MD
IRS990ScheduleJ/Form990ScheduleJPartII/NontaxableBenefitsFilingOrg00
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