Civic Intelligence

Path Drug Solutions

990 • Fiscal year 2012 • EIN 94-3384500

Jan 01, 2012 to Dec 31, 2012 • Filed on Nov 14, 2013

Organization ProfileWWW.PATH.ORG

View Organization Page

2201 Westlake Avenue No 20098121
Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

27th percentile

0.10x

Higher debt load relative to assets than 27% of similar nonprofits.

2012 filings • 501(c)3 • $25M-$50M nonprofits • Source year 2012

Liabilities / Revenue

Score unavailable

No value available

Liabilities-to-revenue requires both liabilities and revenue on this filing.

Source year 2012

Net Margin

Score unavailable

No value available

Net margin requires both revenue and expenses on this filing.

Source year 2012

Top Officer Pay

Score unavailable

No value available

This filing does not contain officer compensation rows.

Source year 2012

Asset Growth

87th percentile

19%

Faster asset growth than 87% of similar nonprofits.

2012 filings • 501(c)3 • $25M-$50M nonprofits • Annualized from 2011 to 2012

Revenue Growth

Score unavailable

No value available

No valid filing value is available for this score.

Balance Sheet
Liabilities / Assets27th percentile

Assets

Up

$28,999,523

Up $4,714,269 (+19%) from 2011

Net Assets

Up

$26,115,556

Up $3,412,169 (+15%) from 2011

Liabilities

Up

$2,883,967

Up $1,302,100 (+82%) from 2011

Revenue And Expenses
Liabilities / RevenueScore unavailableNet MarginScore unavailable

Revenue

-

No earlier filing loaded for comparison.

Expenses

Down

$11,651,870

Down $2,024,867 (-15%) from 2011

Net Income

-

No earlier filing loaded for comparison.

Historical Trend

Balance Sheet Trend

Asset Growth87th percentile

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$60M$40M$20M$0Assets 2010: $26,215,343Liabilities 2010: $4,437,688Net Assets 2010: $21,777,6552010Assets 2011: $24,285,254Liabilities 2011: $1,581,867Net Assets 2011: $22,703,3872011Assets 2012: $28,999,523Liabilities 2012: $2,883,967Net Assets 2012: $26,115,5562012Assets 2013: $42,859,417Liabilities 2013: $977,931Net Assets 2013: $41,881,4862013Assets 2014: $37,978,413Liabilities 2014: $1,584,692Net Assets 2014: $36,393,7212014Assets 2015: $14,847,024Liabilities 2015: $1,605,303Net Assets 2015: $13,241,7212015Assets 2016: $10,229,897Liabilities 2016: $46,385Net Assets 2016: $10,183,5122016Assets 2017: $7,105,262Liabilities 2017: $708,783Net Assets 2017: $6,396,4792017Assets 2018: $0Liabilities 2018: $0Net Assets 2018: $02018

Highlighted filing

2012

Assets$28,999,523
Liabilities$2,883,967
Net Assets$26,115,556
Open 2012 Filing

Operations Trend

Revenue GrowthScore unavailable

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$30M$20M$10M$0-$10MExpenses 2010: $17,804,3432010Expenses 2011: $13,676,7372011Expenses 2012: $11,651,8702012Revenue 2013: $24,724,025Expenses 2013: $8,958,738Net Income 2013: $15,765,2872013Revenue 2014: $5,270,106Expenses 2014: $10,759,489Net Income 2014: -$5,489,3832014Revenue 2015: $7,139,715Expenses 2015: $5,997,711Net Income 2015: $1,142,0042015Revenue 2016: $216,478Expenses 2016: $3,275,717Net Income 2016: -$3,059,2392016Revenue 2017: $201,146Expenses 2017: $2,548,179Net Income 2017: -$2,347,0332017Revenue 2018: $2,972,163Expenses 2018: $3,576,203Net Income 2018: -$604,0402018

Highlighted filing

2012

Revenue-
Expenses$11,651,870
Net Income-
Open 2012 Filing
Jump To
Filing Snapshot
Filing Period
Jan 1, 2012 to Dec 31, 2012
Signed
Nov 14, 2013
Return Version
2012v2.1
Gross Receipts
$24,403,194
Mission and Program Overview

Mission

Path drug solutions (pds) develops and advances safe and effective medicines for the prevention and treatment of diseases disproportionately affecting women and children in low-resource settings. We work with a variety of public- and private-sector stakeholders to build cross-sector collaborations, secure intellectual property, revisit promising drugs or drug candidates that have been set aside for nonmedical reasons (e.g., lack of earning potential), and harness scientific and manufacturing capacity in high- and low- or middle-income countries to ensure drugs are available, accessible, and affordable to all those who need them.

Major Activities

Activity 2
Maternal and child health: we completed two phase 1 clinical studies in the united states for a new drug candidate to treat acute secretory diarrhea. This work is part of path's wide-reaching efforts to combat diarrhea, one of the leading causes of death among children under five. The studies showed that the treatment was safe, well tolerated, and had no serious adverse events. Based on these outcomes, we will continue to advance this promising drug candidate through further clinical trials in bangladesh in 2013.
Activity 3
Health technologies: we performed work, which will continue into next year, on developing a new formulation of oral rehydration solution that addresses symptoms caused by diarrhea.
Filing and Contact Details

Filer

EIN
94-3384500
Raw XML AppendixShowing 400 of 880 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Activity2/Description0MATERNAL AND CHILD HEALTH: WE COMPLETED TWO PHASE 1 CLINICAL STUDIES IN THE UNITED STATES FOR A NEW DRUG CANDIDATE TO TREAT ACUTE SECRETORY DIARRHEA. THIS WORK IS PART OF PATH'S WIDE-REACHING EFFORTS TO COMBAT DIARRHEA, ONE OF THE LEADING CAUSES OF DEATH AMONG CHILDREN UNDER FIVE. THE STUDIES SHOWED THAT THE TREATMENT WAS SAFE, WELL TOLERATED, AND HAD NO SERIOUS ADVERSE EVENTS. BASED ON THESE OUTCOMES, WE WILL CONTINUE TO ADVANCE THIS PROMISING DRUG CANDIDATE THROUGH FURTHER CLINICAL TRIALS IN BANGLADESH IN 2013.
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IRS990/Description0EMERGING AND EPIDEMIC DISEASES: ALTHOUGH MANY POOR COUNTRIES NEED NEW, MORE EFFECTIVE, AND LOWER-COST MEDICINES TO MEET HEALTH CHALLENGES (INCLUDING MALARIA, DIARRHEA, AND NEGLECTED AND TROPICAL DISEASES), RESEARCH AND DEVELOPMENT FOR THESE DRUGS MAY NOT BE A PRIORITY FOR COMMERCIAL PHARMACEUTICAL GROUPS. PDS OVERCOMES THIS BARRIER BY CREATING CROSS-SECTOR COLLABORATIONS, OPENING DOORS FOR THE SHARING AND DONATION OF INTELLECTUAL PROPERTY, AND HARNESSING THE SCIENTIFIC AND MANUFACTURING CAPACITY OF BOTH DEVELOPED AND DEVELOPING COUNTRIES. WE ASSEMBLE EXPERIENCED AND DEDICATED TEAMS, IDENTIFY PROMISING DRUG CANDIDATES, TRANSLATE THEM INTO SAFE, EFFECTIVE, AND AFFORDABLE MEDICINES, AND COLLABORATE WITH COMPANIES TO MANUFACTURE AND DISTRIBUTE NEWLY APPROVED THERAPIES TO THOSE WHO NEED THEM MOST.IN 2012, THE TEAM ACHIEVED REMARKABLE GAINS, DEVELOPING TRANSFORMATIVE NEW MEDICINES AND RESEARCH WHILE MODELLING AND ADVANCING BEST PRACTICE IN CROSS-SECTOR COLLABORATION.FOR EXAMPLE, THE HIGH COST AND VOLATILE SUPPLY OF ARTEMISININ, THE KEY INGREDIENT IN TOP MALARIA TREATMENTS, CAN PUT THESE LIFESAVING MEDICINES OUT OF REACH FOR PEOPLE WHO ARE MOST AT RISK. WE WORKED WITH PARTNERS TO DEVELOP A SEMISYNTHETIC VERSION OF ARTEMISININ TO SUPPLEMENT FLUCTUATING BOTANICAL SUPPLIES AND, AFTER SUCCESSFULLY COMPLETING PROCESS VALIDATION, PRODUCED SEVERAL TONS OF MATERIALS FOR TESTING BY POTENTIAL CUSTOMERS. PRODUCTION IS SET FOR 40 TONS IN 2013, AND WILL EXPAND SIGNIFICANTLY BY 2014, PROVIDING A MORE DEPENDABLE SUPPLY OF ARTEMISININ, AND ULTIMATELY, LIFESAVING ANTIMALARIAL DRUGS.THE NEW DRUG, AND THE INNOVATIVE SCIENTIFIC PROCESSES THAT ALLOW PRODUCTION AT AN INDUSTRIAL SCALE, ARE BOTH SET TO ACHIEVE GLOBAL IMPACT. IN ADDITION, THE EFFORT DEMONSTRATED SUCCESSFUL COLLABORATION BETWEEN INDUSTRY, SCIENTIFIC, NONPROFIT, AND ACADEMIC PARTNERS. PATH'S TEAM SYNCHRONIZED DIVERGENT GOALS, PROFESSIONAL NORMS, AND INTELLECTUAL PROPERTY CONSIDERATIONS TO BRING THE PRODUCT TO COMMERCIAL PRODUCTION, FURTHERING PATHS EXPERIENCE AND REPUTATION AS A LEADER IN CROSS-SECTOR COLLABORATION FOR PUBLIC HEALTH.IN ADDITION, PDS ADVANCED A NEW TREATMENT OPTION FOR VISCERAL LEISHMANIASIS, A NEGLECTED INFECTIOUS DISEASE ENDEMIC IN 79 COUNTRIES THAT IS TRANSMITTED THROUGH THE BITE OF SAND FLIES, CAUSING SWELLING OF KEY ORGANS, ANEMIA, AND DEATH IF LEFT UNTREATED. WE ADVANCED A NEW ANTIBIOTIC CALLED THE PAROMOMYCIN INTRAMUSCULAR INJECTION (PMIM), DEVELOPED TO TREAT THE DISEASE. IN 2012, IT WAS REGISTERED BY THE GOVERNMENT OF NEPAL, AND WE COMPLETED A PHASE 3(B) CLINICAL TRIAL IN BANGLADESH, SUPPORTING EFFORTS TO REGISTER PMIM THERE AND CONTRIBUTING TO A NATIONAL ELIMINATION STRATEGY.
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Document Assets

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Filings

Displayed year

2012 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.

Open filing
Assets
$28,999,523
Liabilities
$2,883,967
Net assets
$26,115,556
Revenue
-
Expenses
$11,651,870
Net income
-
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2018Detailed filing. Detailed filing data is available for this year.$0.00$0.00$0.00$2.97$3.58$0.60
2017Detailed filing. Detailed filing data is available for this year.$7.11$0.71$6.40$0.20$2.55$2.35
2016Detailed filing. Detailed filing data is available for this year.$10.2$0.05$10.2$0.22$3.28$3.06
2015Detailed filing. Detailed filing data is available for this year.$14.8$1.61$13.2$7.14$6.00$1.14
2014Detailed filing. Detailed filing data is available for this year.$38.0$1.58$36.4$5.27$10.8$5.49
2013Detailed filing. Detailed filing data is available for this year.$42.9$0.98$41.9$24.7$8.96$15.8
2012Facts available. Structured filing facts are available, but richer extracted sections are limited.$29.0$2.88$26.1$11.7
2011Facts available. Structured filing facts are available, but richer extracted sections are limited.$24.3$1.58$22.7$13.7
2010Facts available. Structured filing facts are available, but richer extracted sections are limited.$26.2$4.44$21.8$17.8