Civic Intelligence

Medical Technology and Practice Patterns

EIN 52-1483174 • 501(c)3 • Bethesda, MD

View Organization Page

Profile

Founded in 1986, mtppi is a research organization specializing in health service research, education and health policy analysis of new and emerging technologies.

4800 Hampden Lane 200Bethesda, MD 20814

www.mtppi.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

65th percentile

0.18x

Higher debt load relative to assets than 65% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Liabilities / Revenue

87th percentile

0.87x

Higher debt load relative to revenue than 87% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Net Margin

13th percentile

-24%

Higher net margin than 13% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Top Officer Pay

Score unavailable

No value available

No filing with officer rows is available for this organization yet.

Asset Growth

51st percentile

4.1%

Faster asset growth than 51% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Annualized from 2023 to 2024

Revenue Growth

51st percentile

7.5%

Faster revenue growth than 51% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Annualized from 2023 to 2024

Balance Sheet
Liabilities / Assets65th percentile

Assets

Up

$4,303,817

Up $169,658 (+4.1%) from 2023

Liabilities

Up

$790,294

Up $182,828 (+30%) from 2023

Net Assets

Down

$3,513,523

Down $13,170 (-0.4%) from 2023

Operations
Liabilities / Revenue87th percentileNet Margin13th percentile

Revenue

Up

$911,470

Up $63,647 (+7.5%) from 2023

Expenses

Up

$1,125,755

Up $17,960 (+1.6%) from 2023

Net Income

Up

-$214,285

Up $45,687 (+18%) from 2023

Trend Graphs

Balance Sheet Trend

Asset Growth51st percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$8.0M$6.0M$4.0M$2.0M$0Assets 2011: $5,576,530Liabilities 2011: $45,301Net Assets 2011: $5,531,2292011Assets 2012: $7,227,521Liabilities 2012: $49,121Net Assets 2012: $7,178,4002012Assets 2013: $5,808,245Liabilities 2013: $527,222Net Assets 2013: $5,281,0232013Assets 2014: $6,383,143Liabilities 2014: $1,080,720Net Assets 2014: $5,302,4232014Assets 2015: $5,115,353Liabilities 2015: $298,903Net Assets 2015: $4,816,4502015Assets 2016: $5,186,495Liabilities 2016: $504,607Net Assets 2016: $4,681,8882016Assets 2017: $5,167,113Liabilities 2017: $280,917Net Assets 2017: $4,886,1962017Assets 2018: $4,363,826Liabilities 2018: $267,626Net Assets 2018: $4,096,2002018Assets 2019: $4,643,164Liabilities 2019: $532,375Net Assets 2019: $4,110,7892019Assets 2020: $4,874,126Liabilities 2020: $598,014Net Assets 2020: $4,276,1122020Assets 2021: $4,682,047Liabilities 2021: $402,156Net Assets 2021: $4,279,8912021Assets 2022: $3,990,256Liabilities 2022: $500,394Net Assets 2022: $3,489,8622022Assets 2023: $4,134,159Liabilities 2023: $607,466Net Assets 2023: $3,526,6932023Assets 2024: $4,303,817Liabilities 2024: $790,294Net Assets 2024: $3,513,5232024

Highlighted filing

2024

Assets$4,303,817
Liabilities$790,294
Net Assets$3,513,523
Open 2024 Filing

Operations Trend

Revenue Growth51st percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$3.0M$2.0M$1.0M$0-$1.0MRevenue 2011: $1,037,543Expenses 2011: $918,614Net Income 2011: $118,9292011Revenue 2012: $2,722,120Expenses 2012: $1,074,949Net Income 2012: $1,647,1712012Revenue 2013: $1,910,922Expenses 2013: $1,772,181Net Income 2013: $138,7412013Revenue 2014: $1,202,426Expenses 2014: $1,515,355Net Income 2014: -$312,9292014Revenue 2015: $779,112Expenses 2015: $1,278,397Net Income 2015: -$499,2852015Revenue 2016: $1,006,652Expenses 2016: $1,317,942Net Income 2016: -$311,2902016Revenue 2017: $1,115,632Expenses 2017: $1,283,584Net Income 2017: -$167,9522017Revenue 2018: $791,621Expenses 2018: $1,263,783Net Income 2018: -$472,1622018Revenue 2019: $889,949Expenses 2019: $1,310,800Net Income 2019: -$420,8512019Revenue 2020: $1,011,370Expenses 2020: $1,257,064Net Income 2020: -$245,6942020Revenue 2021: $864,770Expenses 2021: $1,208,161Net Income 2021: -$343,3912021Revenue 2022: $967,520Expenses 2022: $1,106,081Net Income 2022: -$138,5612022Revenue 2023: $847,823Expenses 2023: $1,107,795Net Income 2023: -$259,9722023Revenue 2024: $911,470Expenses 2024: $1,125,755Net Income 2024: -$214,2852024

Highlighted filing

2024

Revenue$911,470
Expenses$1,125,755
Net Income-$214,285
Open 2024 Filing

Filings

Most recent year

2024 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$4,303,817
Liabilities
$790,294
Net assets
$3,513,523
Revenue
$911,470
Expenses
$1,125,755
Net income
-$214,285
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$4.30$0.79$3.51$0.91$1.13$0.21
2023Detailed filing. Detailed filing data is available for this year.$4.13$0.61$3.53$0.85$1.11$0.26
2022Detailed filing. Detailed filing data is available for this year.$3.99$0.50$3.49$0.97$1.11$0.14
2021Detailed filing. Detailed filing data is available for this year.$4.68$0.40$4.28$0.86$1.21$0.34
2020Detailed filing. Detailed filing data is available for this year.$4.87$0.60$4.28$1.01$1.26$0.25
2019Detailed filing. Detailed filing data is available for this year.$4.64$0.53$4.11$0.89$1.31$0.42
2018Detailed filing. Detailed filing data is available for this year.$4.36$0.27$4.10$0.79$1.26$0.47
2017Detailed filing. Detailed filing data is available for this year.$5.17$0.28$4.89$1.12$1.28$0.17
2016Detailed filing. Detailed filing data is available for this year.$5.19$0.50$4.68$1.01$1.32$0.31
2015Detailed filing. Detailed filing data is available for this year.$5.12$0.30$4.82$0.78$1.28$0.50
2014Detailed filing. Detailed filing data is available for this year.$6.38$1.08$5.30$1.20$1.52$0.31
2013Summary only. Only limited summary data is available for this year.$5.81$0.53$5.28$1.91$1.77$0.14
2012Summary only. Only limited summary data is available for this year.$7.23$0.05$7.18$2.72$1.07$1.65
2011Summary only. Only limited summary data is available for this year.$5.58$0.05$5.53$1.04$0.92$0.12
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Nov 15, 2025
Return Version
2024v5.2
Gross Receipts
$911,470
Mission and Program Overview

Mission

Founded in 1986, medical technology and practice patterns institute(mtppi) is a research organization specializing in health service research, education and health policy analysis of new and emerging technologies.

Founded in 1986, mtppi is a research organization specializing in health service research, education and health policy analysis of new and emerging technologies.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$3,493,448$3,705,409▲ $211,961
Cash and Non-Interest-Bearing Accounts$209,170$290,072▲ $80,902
Pledges and Grants Receivable$407,180$131,562▼ $275,618
Investments Other Securities$14,480$5,300▼ $9,180
Land, Buildings, and Equipment, Net$0$2,469▲ $2,469
Total Assets$4,134,159$4,303,817▲ $169,658
Other Assets Total$9,881$169,005▲ $159,124
Liabilities
Other Liabilities$571,038$776,042▲ $205,004
Accounts Payable and Accrued Expenses$36,428$14,252▼ $22,176
Total Liabilities$607,466$790,294▲ $182,828
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$3,526,693$3,513,523▼ $13,170
Total Net Assets Fund Balance$3,526,693$3,513,523▼ $13,170
Total Liabilities and Net Assets / Fund Balance$4,134,159$4,303,817▲ $169,658

Asset Categories

AssetBook ValueDepreciationBasis
Other Land Buildings$2,469$5,609$8,078
Compensation and Service Providers
Top Officer PayScore unavailable

Employees

NameTitleFull / Part TimeBaseOtherTotal
Mr Dennis CotterPresidentFT$239,027$2,988$242,015
Dr Mae Thamer-nallResearch DirectorFT$195,387$6,500$201,887
Dr Yi ZhangResearch AssociateFT$158,109$7,510$165,619
Nicholas Hamilton-cotterDirector of DevelopmentFT$150,000$5,750$155,750

Board Members and Trustees

NameTitle
Dr Andrew NarvaBoard Member
Mr Amit LambaBoard Member
Tom KeonTreasurer
Revenue and Support

Revenue Composition

Contributions and Grants
$454,198
Program Service Revenue
$196,596
Investment Income
$260,413
Other Revenue
$263
All Other Contributions
$454,198
Change in Net Assets
$-214,285
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Salaries, Compensation, and Employee Benefits$857,975
Other Expenses$267,780
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$408,332$111,359-$519,691
Current Officers, Directors, Trustees, and Key Employees$135,204$105,662-$240,866
Fees for Services Other$80,530$70,561-$151,091
Other Employee Benefits$30,352$27,984-$58,336
Payroll Taxes$24,134$14,948-$39,082
Interest-$34,194-$34,194
Office Expenses$6,972$5,461-$12,433
Other Expenses$4,051$2,717-$4,051
Occupancy$1,904$2,136-$4,040
Information Technology$2,728--$2,728
Depreciation Depletion-$398-$398
All Other Expenses$65$130-$195
Advertising$17$35-$52
Travel$8$9-$17
Total Functional Expenses$739,823$385,932$0$1,125,755
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Interested-Person Transactions

Interested PartyRelationshipDescriptionShared RevenueAmount
Nicholas Hamilton-cotterSon of Dennis Cotter, President of the OrganizationEmployee CompensationNo$150,000
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Line of Credit$633,197
Other Accrued Expenses$142,845
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
Yes
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

“Nicholas hamilton-cotter is the son of dennis cotter”

Form 990, Part VI, Section B, Line 11B

“Draft copy of the form 990 is emailed or mailed via post office as appropriate to the members of the financial committee of mtppi. Each member then sends back his or her approval to the president prior to filing of the form.”

Form 990, Part VI, Section B, Line 12C

“On an annual basis, all personnel subject to the organization's conflict of interest policy are required to review their personal facts and circumstances in order to identify any potential conflicts. If any are identified, the potential conflicts are required to be reported under the procedures described in the policy.”

Form 990, Part VI, Section B, Line 15

“On an annual basis, salaries of the organization's top management official and other key personnel are reviewed by board. The board review consists of the use of compensation studies and other relevant data.”

Form 990, Part VI, Section C, Line 19

“AVAILABLE UPON REQUEST”

Filing and Contact Details

Filer

Filer Name
Medical Technology and Practice Patterns
EIN
52-1483174
Phone
3016524005
Address
4800 HAMPDEN LANE 200, BETHESDA, MD 20814

Signing Officer

Name
Nicholas Hamilton-cotter
Title
Director
Phone
3016524005
Signed
2025-11-15
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Nicholas Hamilton-cotter
Formed
1986
Legal Domicile
Dc
Voting Board Members
4
Independent Board Members
3
Employees
4
Volunteers
0

Preparer

Firm
Lobel Cooper & Associates Pc
Address
6309 EXECUTIVE BLVD, NORTH BETHESDA, MD 20852
Preparer
Andrew S Cooper
Phone
3016377080
Supplemental Narrative

Additional Explanations

Form 990, Part IX, Line 11G

“Consortium and consultants: program service expenses 80,530. Management and general expenses 70,561. Fundraising expenses 0. Total expenses 151,091.”

Financial Statement Notes

PART X, LINE 2:

“For the year ended december 31, 2023, the organizations have documented their consideration of fasb asc 740-10, income taxes, that provides guidance for reporting uncertainty in income taxes and has determined that no material uncertain tax positions qualify for either recognition or disclosure in the consolidated financial statements.”

Raw XML AppendixShowing 400 of 535 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/ActivityOrMissionDesc0FOUNDED IN 1986, MTPPI IS A RESEARCH ORGANIZATION SPECIALIZING IN HEALTH SERVICE RESEARCH, EDUCATION AND HEALTH POLICY ANALYSIS OF NEW AND EMERGING TECHNOLOGIES.
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IRS990/Desc0RESEARCHING BARRIERS TO ARTERIOVENOUS FISTULA USE IN BLACK HEMODIALYSIS PATIENTS IN COLLABORATION WITH THE UNIVERSITY OF ALABAMA AT BIRMINGHAMIN THE FINAL YEAR OF THE 5-YEAR R01 PROJECT WE CONDUCTED TWO MAJOR RESEARCH TASKS. THE FIRST MAJOR TASK WAS TO EXAMINE THE AVF AND AVG MATURATION AND MAINTENANCE PROCEDURAL BURDEN AMONG PATIENTS WHO INITIATE WITH A CVC WITH A LONGER FOLLOW-UP THAN HAD PREVIOUSLY BEEN PUBLISHED AND THAT INCORPORATES ALL SUBSEQUENT ACCESSES AND PROCEDURES (IF THE FIRST ONE FAILED). SPECIFICALLY, IN 2024 WE EXAMINED FOUR CLINICAL SCENARIOS IN THE FIRST YEAR AFTER SURGICAL ACCESS CREATION: (1) MAINTAIN PRIMARY PATENCY, (2) PRIMARY PATENCY LOSS, (3) SECONDARY PATENCY LOSS AFTER AVF/AVG USE, AND (4) AVF/AVG NONUSE. WE ALSO INCLUDED COSTS ASSOCIATED WITH ALL SURGICAL AND PERCUTANEOUS VASCULAR ACCESS PROCEDURES FOR THE DURATION OF PATIENT FOLLOW-UP, INCLUDING PROCEDURES OCCURRING AFTER THE FIRST ACCESS FAILED. VASCULAR ACCESS COSTS, INCLUDING THE COST OF THE INDEX AVF CREATION, WERE CALCULATED FOR YEARS 1, 2 AND 3 AFTER THE INDEX AVF/AVG CREATION DATE AND TOTAL 3 YEARS AFTER INITIAL VA CREATION. THIS STUDY - WHICH WE ARE CURRENTLY IN THE PROCESS OF WRITING UP -- WILL PROVIDE A MORE COMPREHENSIVE ESTIMATE OF THE TRUE VASCULAR ACCESS COSTS IN PATIENTS WHO INITIALLY RECEIVED AN AVF OR AN AVG. GIVEN THE INCREASED FOCUS ON INDIVIDUALIZING THE TYPE OF DIALYSIS ACCESS BASED ON PATIENT CHARACTERISTICS AND VALUES, THE INFORMATION OBTAINED FROM THIS RESEARCH PROJECT MAY PROVIDE GREATER ACCEPTANCE OF AVGS.THE SECOND MAJOR TASK WAS TO DETERMINE PATIENT PERSPECTIVES ON SELECTION OF PERMANENT VASCULAR ACCESS IN HEMODIALYSIS. GIVEN THAT ARTERIOVENOUS FISTULA (AVF) USE AMONG US HEMODIALYSIS (HD) PATIENTS IS SUBOPTIMAL WE INTERVIEWED A GROUP OF UNDERSERVED HD PATIENTS TO PROBE EXPERIENCES AND PERSPECTIVES SURROUNDING STEPS ALONG THE AVF CARE CONTINUUM, WHICH INCLUDES PLACEMENT, MATURATION, AND USE OF AVFS USING INDIVIDUAL SEMI STRUCTURED INTERVIEWS. TRANSCRIPTS WERE CODED AND THEMATICALLY ANALYZED AMONG 53 BLACK AND 6 WHITE PATIENTS AT DIFFERENT STEPS OF THE AVF CARE CONTINUUM: 29 WERE DIALYZING WITH A CENTRAL VENOUS CATHETER (15 HAD NOT UNDERGONE AVF PLACEMENT, 9 HAD A MATURING AVF, AND 5 HAD A NONFUNCTIONAL AVF) AND 30 WERE DIALYZING WITH AN AVF. WE CODED TRANSCRIPTS USING QUALITATIVE THEMATIC ANALYSIS. THREE THEMES EMERGED: (1) THE CIRCUMSTANCES OF DIALYSIS INITIATION SOMETIMES ALTERED THE TIMELINE OF AV ACCESS PLACEMENT; (2) PATIENTS HAD VARIABLE LEVELS OF KNOWLEDGE OF STEPS ALONG THE AVF CONTINUUM; AND (3) THE LIFE IMPACTS OF DIALYSIS ACCESS WERE A SIGNIFICANT FACTOR IN PATIENTS' EXPERIENCE OF DIALYSIS. THE MAJOR LIMITATION WAS THAT THE STUDY WAS CONDUCTED AT A SINGLE-INSTITUTION. WE CONCLUDED THAT, AMONG A GROUP OF UNDERSERVED HD PATIENTS, PERSPECTIVES SURROUNDING THE AVF CARE CONTINUUM INCLUDED CONSIDERATION OF THE CIRCUMSTANCES OF DIALYSIS INITIATION, PATIENT KNOWLEDGE, AND THE LIFE IMPACTS OF DIALYSIS ACCESS. THESE FINDINGS MAY INFORM TARGETED INTERVENTIONS AIMED AT OPTIMIZING DIALYSIS ACCESS USE AND ADDRESSING DISPARITIES ACROSS THE AVF CONTINUUM. THIS WORK WAS PUBLISHED AS FOLLOWS: PATEL DM, CHURILLA BM, LEE TC, THAMER M, ZHANG Y, ALLON M, CREWS DC. PATIENT PERSPECTIVES ON ARTERIOVENOUS FISTULA PLACEMENT, MATURATION, AND USE: A QUALITATIVE STUDY. KIDNEY MED. 2024 OCT 16;6(12):100919. DOI: 10.1016/J.XKME.2024.100919. ECOLLECTION 2024 DEC. PMID: 39634335
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IRS990/MissionDesc0FOUNDED IN 1986, MTPPI IS A RESEARCH ORGANIZATION SPECIALIZING IN HEALTH SERVICE RESEARCH, EDUCATION AND HEALTH POLICY ANALYSIS OF NEW AND EMERGING TECHNOLOGIES.
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IRS990/ProgSrvcAccomActy2Grp/Desc0GILEAD CO-US-998-7081 EVALUATING GENDER SPECIFIC DISPARITIES IN THE VIRAL HEPATITIS CASCADE:IN THIS PERIOD THE PRIMARY OBJECTIVE WAS TO EXAMINE TIMELY TREATMENT OF CHRONIC HEPATITIS B (CHB) GIVEN THE REDUCTION IN RISKS OF CIRRHOSIS AND HEPATOCELLULAR CARCINOMA. GAPS IN TIMELY TREATMENT HAVE HISTORICALLY PERSISTED, ESPECIALLY AMONG UNDERSERVED SAFETY-NET POPULATIONS. WE AIMED TO EVALUATE GAPS AND DISPARITIES IN CHB TREATMENT IN THE UNITED STATES. ADULTS WITH TREATMENT-NAIVE CHB WITHOUT HUMAN IMMUNODEFICIENCY VIRUS WERE IDENTIFIED FROM 2010 TO 2018 ACROSS 3 SAFETY-NET HEALTH SYSTEMS. CHB TREATMENT ELIGIBILITY WAS ASSESSED USING AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES (AASLD) CRITERIA AND ALTERNATIVE CRITERIA, INCLUDING THE SIMPLIFIED APPROACH FOR HEPATITIS B ALGORITHM. DIFFERENCES IN CHB TREATMENT BETWEEN GROUPS WERE EVALUATED USING ?2 METHODS, ADJUSTED KAPLAN-MEIER METHODS, AND ADJUSTED COX PROPORTIONAL HAZARDS MODELS.WE FOUND THAT AMONG 3749 PATIENTS WITH TREATMENT-NAIVE CHB (51.5% WOMEN, 38.7% WHITE, 33.7% AFRICAN AMERICAN, 19.6% ASIAN, 24.6% CIRRHOSIS), 30.0% WERE AASLD TREATMENT ELIGIBLE, AMONG WHOM 31.0% WERE TREATED. MEN WERE MORE LIKELY THAN WOMEN TO BE TREATED (33.5% VS 26.6%, P < .01). ON MULTIVARIABLE REGRESSION, THERE REMAINED A TREND TOWARD GREATER TREATMENT IN MEN VERSUS WOMEN (ADJUSTED HAZARD RATIO [AHR], 1.21 [95% CONFIDENCE INTERVAL {CI}, .96-1.54]). DISPARITIES BY RACE/ETHNICITY AND INSURANCE STATUS WERE OBSERVED. WHEN EXPLORING OUTCOMES USING SABA CRITERIA, SIMILAR TRENDS WERE OBSERVED. AMONG TREATMENT-ELIGIBLE PATIENTS, GREATER LIKELIHOOD OF TREATMENT WAS OBSERVED IN MEN VERSUS WOMEN (AHR, 1.40 [95% CI, 1.14-1.70]) AND IN ASIANS VERSUS WHITES (AHR, 1.50 [95% CI, 1.16-1.94]). WE CONCLUDED THAT AMONG AN ETHNICALLY DIVERSE MULTICENTER SAFETY-NET COHORT OF CHB PATIENTS, LESS THAN ONE-THIRD OF TREATMENT-ELIGIBLE PATIENTS RECEIVED ANTIVIRAL TREATMENT. SIGNIFICANT DISPARITIES IN CHB TREATMENT WERE OBSERVED BY SOCIODEMOGRAPHIC CHARACTERISTICS. THESE FINDINGS RESULTED IN A PUBLICATION AS FOLLOWS: WONG RJ, JAIN MK, NIU B, THERAPONDOS G, KSHIRSAGAR O, THAMER M. SOCIODEMOGRAPHIC DISPARITIES IN HEPATITIS B TREATMENT: A REAL-WORLD ANALYSIS OF 3 SAFETY-NET HEALTH SYSTEMS IN THE UNITED STATES. OPEN FORUM INFECT DIS. 2024 OCT 1;11(10):OFAE571. DOI: 10.1093/OFID/OFAE571. ECOLLECTION 2024 OCT. PMID: 39411222
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IRS990/ProgSrvcAccomActy3Grp/Desc0NIMHD R01 MD017063-01 RACIAL AND ETHNIC DISPARITIES IN HCC SURVEILLANCEIN 2024, WE FOCUSED ON TWO RESEARCH AIMS: AIM 1 WAS TO EVALUATE GAPS AND DISPARITIES IN HCC SURVEILLANCE AMONG ADULTS WITH CIRRHOSIS ACROSS FOUR SAFETY-NET HEALTH SYSTEMS IN THE U.S. WE IDENTIFIED ADULTS WITH CIRRHOSIS FROM MARCH 1, 2017 TO FEBRUARY 28, 2022 ACROSS FOUR SAFETY-NET HEALTH SYSTEMS IN CALIFORNIA, FLORIDA, OHIO, AND TEXAS. CIRRHOSIS WAS IDENTIFIED USING ESTABLISHED DEFINITIONS BASED ON ICD-9/10 CODES. PATIENTS WITH BASELINE HCC DIAGNOSIS WERE EXCLUDED. THE PRIMARY OUTCOME WAS RECEIPT OF HCC SURVEILLANCE IMAGING (ULTRASOUND, CT, OR MRI SCANS OF THE ABDOMEN) WITHIN FIRST 6 MONTHS (HCC6MO) OF CIRRHOSIS DIAGNOSIS DURING THE STUDY PERIOD. AMONG A MULTI-CENTER SAFETY-NET COHORT OF CIRRHOSIS PATIENTS, OVER 70% RECEIVED SOME FORM OF ABDOMINAL IMAGING WITHIN 6 MONTHS, BUT LESS THAN 30% RECEIVED IMAGING SPECIFICALLY FOR AN INDICATION OF HCC SURVEILLANCE. WE CONCLUDED THAT SIGNIFICANT DISPARITIES IN HCC SURVEILLANCE WERE OBSERVED ACROSS SOCIODEMOGRAPHIC FACTORS. THESE FINDINGS WERE PRESENTED AT THE 2024 AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES (AASLD) CONFERENCE: GAPS AND DISPARITIES IN HEPATOCELLULAR CARCINOMA SURVEILLANCE AMONG A MULTI-CENTER SAFETY-NET COHORT OF ADULTS WITH CIRRHOSIS. ROBERT J. WONG, PATRICIA JONES, BOLIN NIU, PAULO PINHEIRO, MAE THAMER5, ONKAR KSHIRSAGAR, YI ZHANG, ET AL. POSTER PRESENTATION AT AASLD NOVEMBER 2024 SAN DIEGO CONVENTION CENTER SAN DIEGO CA.AIM 2 WAS TO EVALUATE CLINICIAN-LEVEL FACTORS CONTRIBUTING TO UNDERUSE OF HCC SURVEILLANCE IN PATIENTS WITH CIRRHOSIS. SURVEILLANCE FOR HEPATOCELLULAR CARCINOMA (HCC) IN PATIENTS WITH CIRRHOSIS IS UNDERUSED. WE SOUGHT TO IDENTIFY POTENTIALLY MODIFIABLE FACTORS TO ADDRESS BARRIERS IN HCC SURVEILLANCE IS CRITICAL TO IMPROVE PATIENT OUTCOMES. WE CONDUCTED A SURVEY STUDY THAT INCLUDED PRIMARY CARE CLINICIANS (PCCS) AND GASTROENTEROLOGY AND HEPATOLOGY CLINICIANS AT 5 SAFETY-NET HEALTH SYSTEMS IN THE US. CLINICIANS WERE SURVEYED FROM MARCH 15 TO SEPTEMBER 15, 2023, TO ASSESS KNOWLEDGE, ATTITUDES, BELIEFS, PERCEIVED BARRIERS, AND COVID-19-RELATED DISRUPTIONS IN HCC SURVEILLANCE IN PATIENTS WITH CIRRHOSIS. THE MAIN OUTCOME MEASURES WERE HCC SURVEILLANCE KNOWLEDGE THAT WAS ASSESSED WITH 6 QUESTIONS QUERYING THE RESPONDENT'S ABILITY TO CORRECTLY IDENTIFY APPROPRIATE USE OF HCC SURVEILLANCE. ATTITUDES, PERCEIVED BARRIERS, AND BELIEFS REGARDING HCC SURVEILLANCE AND PERCEIVED IMPACT OF THE COVID-19 PANDEMIC-RELATED DISRUPTIONS WITH HCC SURVEILLANCE WERE ASSESSED WITH A SERIES OF STATEMENTS USING A 4-POINT LIKERT SCALE AND COMPARED PCCS AND GASTROENTEROLOGY AND HEPATOLOGY CLINICIANS.OVERALL, 347 OF 1362 CLINICIANS RESPONDED TO THE SURVEY (25.5% RESPONSE RATE), AMONG WHOM 142 OF 237 (59.9%) WERE PCCS, 48 OF 237 (20.3%) GASTROENTEROLOGY AND HEPATOLOGY, 190 OF 236 (80.5%) WERE DOCTORS OF MEDICINE AND DOCTORS OF OSTEOPATHIC MEDICINE, AND 46 OF 236 (19.5%) WERE ADVANCED PRACTICE CLINICIANS. ON HCC KNOWLEDGE ASSESSMENT, 144 OF 270 (53.3%) SCORED 5 OR MORE OF 6 QUESTIONS CORRECTLY, 37 OF 48 (77.1%) AMONG GASTROENTEROLOGY AND HEPATOLOGY VS 65 OF 142 (45.8%) AMONG PCCS (P < .001). THOSE WITH HIGHER HCC KNOWLEDGE SCORES WERE LESS LIKELY TO REPORT BARRIERS TO HCC SURVEILLANCE. PCCS WERE MORE LIKELY TO REPORT INADEQUATE TIME TO DISCUSS HCC SURVEILLANCE (37 OF 139 [26.6%] VS 2 OF 48 [4.2%]; P = .001), DIFFICULTY IDENTIFYING PATIENTS WITH CIRRHOSIS (82 OF 141 [58.2%] VS 5 OF 48 [10.4%]; P < .001), AND WERE NOT UP-TO-DATE WITH HCC SURVEILLANCE GUIDELINES (87 OF 139 [62.6%] VS 5 OF 48 [10.4%]; P < .001) COMPARED WITH GASTROENTEROLOGY AND HEPATOLOGY CLINICIANS. WHILE MOST ACKNOWLEDGED DELAYS DURING THE COVID-19 PANDEMIC, 62 OF 136 PCCS (45.6%) AND 27 OF 45 GASTROENTEROLOGY AND HEPATOLOGY CLINICIANS (60.0%) REPORTED THAT PATIENTS WITH CIRRHOSIS COULD CURRENTLY COMPLETE HCC SURVEILLANCE WITHOUT DELAYS. WE CONCLUDED THAT IN THIS SURVEY STUDY, IMPORTANT GAPS IN KNOWLEDGE AND PERCEIVED BARRIERS TO HCC SURVEI
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IRS990/ProgSrvcAccomActyOtherGrp/Desc0HOSPITAL ACQUIRED INFECTIONS IN HEMODIALYSIS POPULATIONMTPPI RESEARCHERS WORKED AS SUBCONTRACTORS TO LIFESPAN HEALTH TO RESEARCH HOSPITAL ACQUIRED INFECTIONS IN HEMODIALYSIS PATIENT POPULATION.
IRS990/ProgSrvcAccomActyOtherGrp/Desc1AMGEN 16465587169 CADAVERIC KIDNEY TRANSPLANTATION OUTCOMES AMONG DIALYSIS AND GOUT PATIENTSIN 2024, MTPPI CONTINUED ITS COLLABORATION WITH AMGEN EXAMINING THE ROLE OF GOUT ACROSS THE DIALYSIS-WAITLIST-TRANSPLANT CONTINUUM IN THE UNITED STATES. SPECIFICALLY, USING USRDS STANDARD ANALYTIC FILES FROM 2016-2021 LINKED WITH MEDICARE CLAIMS AND TRANSPLANT REGISTRY DATA, THE TEAM FINALIZED CONSTRUCTION OF THREE NATIONAL LONGITUDINAL COHORTS REPRESENTING INCIDENT DIALYSIS PATIENTS, TRANSPLANT WAITLIST CANDIDATES, AND FIRST KIDNEY TRANSPLANT RECIPIENTS. MONTHLY EXPANDED DATA STRUCTURES WERE DEVELOPED TO MODEL GOUT AS A TIME-VARYING EXPOSURE BASED ON VALIDATED ICD-10 CODES, WHILE CAPTURING CONTEMPORANEOUS CHANGES IN HOSPITALIZATION PATTERNS, CARDIOVASCULAR EVENTS, AND COMORBIDITY BURDEN. THESE DATA SUPPORTED IMPLEMENTATION OF MARGINAL STRUCTURAL MODELS WITH STABILIZED INVERSE-PROBABILITY WEIGHTS TO ADDRESS CONFOUNDING FROM BOTH BASELINE AND TIME-VARYING CLINICAL FACTORS.THE ANALYSES PERFORMED IN 2024 REVEALED THAT GOUT IS ASSOCIATED WITH CONSISTENTLY ADVERSE OUTCOMES ACROSS THE KIDNEY FAILURE AND TRANSPLANT CONTINUUM. AMONG PATIENTS INITIATING DIALYSIS, GOUT WAS LINKED TO SUBSTANTIALLY HIGHER MORTALITY AND A REDUCED FIVE-YEAR CUMULATIVE PROBABILITY OF TRANSPLANT WAITLISTING, DESPITE NON-SIGNIFICANT ADJUSTED CAUSE-SPECIFIC HAZARD RATIOS FOR WAITLISTING ITSELF. AMONG WAITLISTED CANDIDATES, GOUT WAS ASSOCIATED WITH A LOWER LIKELIHOOD OF RECEIVING A DECEASED-DONOR KIDNEY TRANSPLANT AND ELEVATED WAITLIST MORTALITY. AMONG TRANSPLANT RECIPIENTS, GOUT WAS ASSOCIATED WITH HIGHER RISK OF DEATH-CENSORED GRAFT FAILURE AS WELL AS HIGHER POST-TRANSPLANT MORTALITY. THESE FINDINGS WERE ROBUST IN SENSITIVITY ANALYSES AND REPRESENT THE MOST COMPREHENSIVE NATIONAL EVALUATION TO DATE OF GOUT AS A RISK FACTOR FOR WORSE OUTCOMES IN ESKD AND TRANSPLANT POPULATIONS.IN 2024, THE PROJECT'S ANALYTIC PROGRESS RESULTED IN THE ACCEPTANCE OF TWO NATIONAL ABSTRACTS REFLECTING DISSEMINATION OF THE DIALYSIS AND WAITLIST/TRANSPLANT FINDINGS:NATIONAL KIDNEY FOUNDATION / AJKD (ACCEPTED 2024) PARAJULI S, ZHANG Y, MARDER B. ASSOCIATION OF GOUT WITH ACCESS TO KIDNEY TRANSPLANT WAITLISTING AMONG HEMODIALYSIS PATIENTS. PUBLISHED AS ABSTRACT #G-574 IN AJKD; PRESENTED AT NKF SPRING CLINICAL MEETINGS 2025. DOI:10.1053/J.AJKD.2025.02.575AMERICAN SOCIETY OF NEPHROLOGY KIDNEY WEEK (ACCEPTED 2024) GOUT IS ASSOCIATED WITH WORSE WAIT-LIST OUTCOMES IN PATIENTS ON DIALYSIS AWAITING KIDNEY TRANSPLANT. ABSTRACT FR-PO0973, ASN KIDNEY WEEK 2025. DOI:10.1681/ASN.2025K2D0SMEKTHESE ABSTRACT ACCEPTANCES IN 2024 REFLECT THE SCIENTIFIC READINESS AND COMPLETENESS OF THE PROJECT'S ANALYTIC WORK DURING THE YEAR. ADDITIONAL MATERIALS, INCLUDING A FULL MANUSCRIPT INTEGRATING THE DIALYSIS, WAITLIST, AND TRANSPLANT RESULTS, WERE DRAFTED IN LATE 2024. OVERALL, THE 2024 ACCOMPLISHMENTS UNDERSCORE GOUT AS AN IMPORTANT, UNDERRECOGNIZED CONTRIBUTOR TO MORTALITY, TRANSPLANT ACCESS BARRIERS, AND GRAFT FAILURE RISK ACROSS THE KIDNEY TRANSPLANT CONTINUUM.
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IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/CompReportPrior990RltdOrgsAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/CompReportPrior990RltdOrgsAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/CompReportPrior990RltdOrgsAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/CompReportPrior990RltdOrgsAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompensationFlngOrgAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompensationFlngOrgAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompensationFlngOrgAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompensationFlngOrgAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompRltdOrgsAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompRltdOrgsAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompRltdOrgsAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/DeferredCompRltdOrgsAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsFilingOrgAmt02988
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsFilingOrgAmt16500
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsFilingOrgAmt27510
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsFilingOrgAmt35750
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsRltdOrgsAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsRltdOrgsAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsRltdOrgsAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/NontaxableBenefitsRltdOrgsAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationFilingOrgAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationFilingOrgAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationFilingOrgAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationFilingOrgAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationRltdOrgsAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationRltdOrgsAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationRltdOrgsAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/OtherCompensationRltdOrgsAmt30
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/PersonNm0MR DENNIS COTTER
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/PersonNm1DR MAE THAMER-NALL
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/PersonNm2DR YI ZHANG
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/PersonNm3NICHOLAS HAMILTON-COTTER
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TitleTxt0PRESIDENT
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TitleTxt1RESEARCH DIRECTOR
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TitleTxt2RESEARCH ASSOCIATE
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TitleTxt3DIRECTOR OF DEVELOPMENT
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationFilingOrgAmt0242015
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationFilingOrgAmt1201887
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationFilingOrgAmt2165619
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationFilingOrgAmt3155750
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationRltdOrgsAmt00
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationRltdOrgsAmt10
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationRltdOrgsAmt20
IRS990ScheduleJ/RltdOrgOfficerTrstKeyEmplGrp/TotalCompensationRltdOrgsAmt30
IRS990ScheduleJ/SeverancePaymentInd00
IRS990ScheduleJ/SupplementalInformationDetail/ExplanationTxt0ON AN ANNUAL BASIS, SALARIES OF THE ORGANIZATION'S TOP MANAGEMENT OFFICIAL AND OTHER KEY PERSONNEL ARE REVIEWED BY BOARD. THE BOARD REVIEW CONSISTS OF THE USE OF COMPENSATION STUDIES AND OTHER RELEVANT DATA.
IRS990ScheduleJ/SupplementalInformationDetail/FormAndLineReferenceDesc0PART I, LINE 3

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