Civic Intelligence

Quantum Leap Healthcare Collaborative

EIN 20-4284925 • 501(c)3 • San Francisco, CA

View Organization Page

Profile

The mission of quantum leap healthcare collarborative is to provide management and financial support to healthcare research organizations, particularly involving breast cancer research and treatment.

580 California Street 1200San Francisco, CA 94104

www.quantumleaphealth.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

80th percentile

0.72x

Higher debt load relative to assets than 80% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Liabilities / Revenue

62nd percentile

0.63x

Higher debt load relative to revenue than 62% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Net Margin

5th percentile

-37%

Higher net margin than 5% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Top Officer Pay

Score unavailable

No value available

No filing with officer rows is available for this organization yet.

Asset Growth

2nd percentile

-31%

Faster asset growth than 2% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2023 to 2024

Revenue Growth

31st percentile

0.9%

Faster revenue growth than 31% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2023 to 2024

Balance Sheet
Liabilities / Assets80th percentile

Assets

Down

$40,228,761

Down $17,973,199 (-31%) from 2023

Liabilities

Down

$28,835,901

Down $538,822 (-1.8%) from 2023

Net Assets

Down

$11,392,860

Down $17,434,377 (-60%) from 2023

Operations
Liabilities / Revenue62nd percentileNet Margin5th percentile

Revenue

Up

$45,532,346

Up $384,447 (+0.9%) from 2023

Expenses

Up

$62,568,780

Up $14,809,338 (+31%) from 2023

Net Income

Down

-$17,036,434

Down $14,424,891 (-552%) from 2023

Trend Graphs

Balance Sheet Trend

Asset Growth2nd percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$80M$60M$40M$20M$0-$20MAssets 2010: $603,645Liabilities 2010: $35,786Net Assets 2010: $567,8592010Assets 2011: $690,689Liabilities 2011: $68,342Net Assets 2011: $622,3472011Assets 2012: $1,129,206Liabilities 2012: $35,358Net Assets 2012: $1,093,8482012Assets 2013: $8,305,160Liabilities 2013: $337,511Net Assets 2013: $7,967,6492013Assets 2014: $5,173,469Liabilities 2014: $5,265,643Net Assets 2014: -$92,1742014Assets 2015: $6,493,314Liabilities 2015: $11,198,715Net Assets 2015: -$4,705,4012015Assets 2016: $8,443,360Liabilities 2016: $10,538,106Net Assets 2016: -$2,094,7462016Assets 2017: $11,141,939Liabilities 2017: $11,349,148Net Assets 2017: -$207,2092017Assets 2018: $13,623,504Liabilities 2018: $13,096,013Net Assets 2018: $527,4912018Assets 2019: $16,681,889Liabilities 2019: $15,939,504Net Assets 2019: $742,3852019Assets 2020: $46,710,842Liabilities 2020: $28,501,320Net Assets 2020: $18,209,5222020Assets 2021: $64,443,428Liabilities 2021: $33,840,706Net Assets 2021: $30,602,7222021Assets 2022: $60,913,948Liabilities 2022: $30,870,765Net Assets 2022: $30,043,1832022Assets 2023: $58,201,960Liabilities 2023: $29,374,723Net Assets 2023: $28,827,2372023Assets 2024: $40,228,761Liabilities 2024: $28,835,901Net Assets 2024: $11,392,8602024

Highlighted filing

2024

Assets$40,228,761
Liabilities$28,835,901
Net Assets$11,392,860
Open 2024 Filing

Operations Trend

Revenue Growth31st percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$80M$60M$40M$20M$0-$20MExpenses 2010: $851,8832010Expenses 2011: $1,684,8962011Revenue 2012: $1,832,041Expenses 2012: $1,360,540Net Income 2012: $471,5012012Revenue 2013: $6,301,012Expenses 2013: $1,367,479Net Income 2013: $4,933,5332013Revenue 2014: $2,241,657Expenses 2014: $10,301,480Net Income 2014: -$8,059,8232014Revenue 2015: $9,066,877Expenses 2015: $13,699,037Net Income 2015: -$4,632,1602015Revenue 2016: $11,440,896Expenses 2016: $8,277,669Net Income 2016: $3,163,2272016Revenue 2017: $12,489,295Expenses 2017: $10,601,758Net Income 2017: $1,887,5372017Revenue 2018: $12,445,452Expenses 2018: $11,720,572Net Income 2018: $724,8802018Revenue 2019: $15,089,173Expenses 2019: $14,639,065Net Income 2019: $450,1082019Revenue 2020: $40,966,658Expenses 2020: $23,555,958Net Income 2020: $17,410,7002020Revenue 2021: $56,142,324Expenses 2021: $43,755,562Net Income 2021: $12,386,7622021Revenue 2022: $47,253,845Expenses 2022: $47,240,395Net Income 2022: $13,4502022Revenue 2023: $45,147,899Expenses 2023: $47,759,442Net Income 2023: -$2,611,5432023Revenue 2024: $45,532,346Expenses 2024: $62,568,780Net Income 2024: -$17,036,4342024

Highlighted filing

2024

Revenue$45,532,346
Expenses$62,568,780
Net Income-$17,036,434
Open 2024 Filing

Filings

Most recent year

2024 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$40,228,761
Liabilities
$28,835,901
Net assets
$11,392,860
Revenue
$45,532,346
Expenses
$62,568,780
Net income
-$17,036,434
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$40.2$28.8$11.4$45.5$62.6$17.0
2023Detailed filing. Detailed filing data is available for this year.$58.2$29.4$28.8$45.1$47.8$2.61
2022Detailed filing. Detailed filing data is available for this year.$60.9$30.9$30.0$47.3$47.2$0.01
2021Detailed filing. Detailed filing data is available for this year.$64.4$33.8$30.6$56.1$43.8$12.4
2020Detailed filing. Detailed filing data is available for this year.$46.7$28.5$18.2$41.0$23.6$17.4
2019Detailed filing. Detailed filing data is available for this year.$16.7$15.9$0.74$15.1$14.6$0.45
2018Detailed filing. Detailed filing data is available for this year.$13.6$13.1$0.53$12.4$11.7$0.72
2017Detailed filing. Detailed filing data is available for this year.$11.1$11.3$0.21$12.5$10.6$1.89
2016Detailed filing. Detailed filing data is available for this year.$8.44$10.5$2.09$11.4$8.28$3.16
2015Detailed filing. Detailed filing data is available for this year.$6.49$11.2$4.71$9.07$13.7$4.63
2014Detailed filing. Detailed filing data is available for this year.$5.17$5.27$0.09$2.24$10.3$8.06
2013Summary only. Only limited summary data is available for this year.$8.31$0.34$7.97$6.30$1.37$4.93
2012Summary only. Only limited summary data is available for this year.$1.13$0.04$1.09$1.83$1.36$0.47
2011Facts available. Structured filing facts are available, but richer extracted sections are limited.$0.69$0.07$0.62$1.68
2010Facts available. Structured filing facts are available, but richer extracted sections are limited.$0.60$0.04$0.57$0.85
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Nov 17, 2025
Return Version
2024v5.2
Gross Receipts
$123,751,223
Mission and Program Overview

Mission

The mission of Quantum Leap Healthcare Collaborative is to provide management and financial support to healthcare research organizations, particularly involving breast cancer research and treatment.

The mission of quantum leap healthcare collarborative is to provide (continued on schedule o)management and financial support to healthcare research organizations, particularly involving breast cancer research and treatment.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$42,672,001$20,130,413▼ $22,541,588
Accounts Receivable$8,639,920$16,199,006▲ $7,559,086
Cash and Non-Interest-Bearing Accounts$249,898$2,817,987▲ $2,568,089
Prepaid Expenses and Deferred Charges$725,047$683,729▼ $41,318
Savings and Temporary Cash Investments$5,385,955$206,247▼ $5,179,708
Land, Buildings, and Equipment, Net$113,294$80,579▼ $32,715
Pledges and Grants Receivable$279,603$75,000▼ $204,603
Total Assets$58,201,960$40,228,761▼ $17,973,199
Other Assets Total$136,242$35,800▼ $100,442
Liabilities
Accounts Payable and Accrued Expenses$12,880,683$16,757,091▲ $3,876,408
Deferred Revenue$15,030,847$10,615,617▼ $4,415,230
Other Liabilities$1,463,193$1,463,193→ $0
Total Liabilities$29,374,723$28,835,901▼ $538,822
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$28,638,301$11,077,690▼ $17,560,611
Net Assets With Donor Restrictions$188,936$315,170▲ $126,234
Total Net Assets Fund Balance$28,827,237$11,392,860▼ $17,434,377
Total Liabilities and Net Assets / Fund Balance$58,201,960$40,228,761▼ $17,973,199

Asset Categories

AssetBook ValueDepreciationBasis
Other Land Buildings$-10,641$248,388$237,747
Leasehold Improvements$91,220-$91,220
Compensation and Service Providers
Top Officer PayScore unavailable

Employees

NameTitleFull / Part TimeBaseOtherTotal
James PalazzoloCEOFT$600,144$180,506$780,650
Kathryn Watson-feinerVice President of FinanceFT$471,944$50,100$522,044
Imogene MdunnVice Pres. Statistics (thru 11/24)FT$308,260$211,563$519,823
Radhika SivaramakrishnaSr. VP, Clinical Ops & ComplianceFT$344,211$57,369$401,580
Philip BeinekeDirector of Biometrics, OncologyFT$317,177$62,825$380,002
Ami OkadaDirector of I-spy Covid TrialFT$292,216$49,851$342,067
Pinaki ChakrabortyVP Quality AssuranceFT$276,863$56,317$333,180
Karyn DigiorgioChief Collaboration OfficerFT$280,507$46,971$327,478
Paul HendersonSr. Director of CollaborationsFT$248,859$58,813$307,672
Adam AsareChief Data OfficerFT$270,697$15,056$285,753
Sara HortonExecutive Director, DiversityFT$241,574$32,535$274,109
Annuska GlasVP Biomarker & InnovationFT$222,484$29,098$251,582
Dave Mandelkern MsChairmanPT$120,000-$120,000

Board Members and Trustees

NameTitle
Anna Barker PhdDirector
Gregory C SimonDirector
Jeffrey PfefferDirector
Lambert Van Der Walde MbaDirector
Lucas De Breed Phd MbaDirector
Mark Simon MbaDirector
Michele MarkusDirector
N Marcus Thygeson Md MphDirector
Robyn Lawrie Rutledge MbaDirector
Susan Foley CfaDirector
Laura EssermanDirector, Co-founder

Highest Paid Contractors

ContractorServicesLocationCompensation
Regents Of Uc San FranciscoClinical ResearchBOX 0897 1855 FOLSOM ST SUITE 42, San Francisco, CA 94143$7,394,491
University Of California San DiegoCell-free Dna Tests9500 GILMAN DRIVE MC 0009, La Jolla, CA 92093-0009$1,651,000
Natera INCClinical Research1720 2ND AVENUE SOUTH AB 990, Birmingham, AL 35294-0109$1,313,529
University Of Alabama At Birmingham - CoClinical Research1720 2ND AVENUE SOUTH AB 990, Birmingham, AL 35294-0109$1,313,529
Yourway Transport INCClinical Packager & Premium Courier6681 SNOWDRIFT RD, Allentown, PA 18106$1,201,250
Revenue and Support

Revenue Composition

Contributions and Grants
$878,580
Program Service Revenue
$42,490,974
Investment Income
$2,241,408
Other Revenue
$-78,616
All Other Contributions
$878,580
Change in Net Assets
$-17,036,434

Noncash Contribution Practices

Property subject to holding requirements
No
Reviewed unusual noncash gifts
No
Third parties used for noncash contributions
No

Noncash Contributions

Contribution TypeContribution CountReported AmountValuation Method
Drugs and Medical Supplies1$395,956Fair Market Value (FMV)
Total Noncash Contributions1$395,956-

Audited Revenue Reconciliation

Revenue per Audited Statements
$45,532,346
Revenue Not Reported on Financial Statements
$0
Revenue Not Reported on Form 990
$-103,655
Total Revenue per Audited Statements
$45,428,691
Total Revenue per Form 990
$45,532,346
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$39,418,442
Salaries, Compensation, and Employee Benefits$23,150,338
Total Fundraising Expense$562,054
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$11,987,556$2,819,655$351,670$15,158,881
Information Technology$3,071,077$517,687$56,720$3,645,484
Current Officers, Directors, Trustees, and Key Employees$1,850,296$1,255,182-$3,105,478
Other Employee Benefits$2,065,148$568,456$55,445$2,689,049
Fees for Services Other$2,405,958$79,148$38,681$2,523,787
Payroll Taxes$1,236,328$360,979$31,649$1,628,956
Other Expenses$1,543,703$179-$1,543,882
Travel$939,557$451,718$5,153$1,396,428
Pension Plan Contributions$431,075$125,864$11,035$567,974
Occupancy$240,424$87,372$6,383$334,179
Fees for Services Accounting-$223,585-$223,585
Office Expenses$76,347$56,496$2,292$135,135
Insurance$80,010$13,065$1,204$94,279
Depreciation Depletion$68,311$19,361$1,822$89,494
Fees for Services Legal-$76,645-$76,645
Fees for Service Investment Mgmnt Fees-$22,019-$22,019
Conferences and Meetings$39$18-$57
Interest$6$6-$12
Total Functional Expenses$55,329,291$6,677,435$562,054$62,568,780

Audited Expense Reconciliation

Line ItemAmount
Total Expenses per Audited Statements$62,863,068
Expenses per Audited Statements$62,568,780
Total Expenses per Form 990$62,568,780
Expenses Not Reported on Form 990$294,288
Expenses Not Reported on Financial Statements$0
Fundraising, Events, and Gaming
Fundraising activities
Yes
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Fundraising Direct Expenses$294,288
Fundraising Gross Income$215,672
Professional Fundraising Fees$0

Fundraising Events

EventGross ReceiptsGross RevenueDirect ExpensesNet Income
Rise Up$215,672$215,672$287,062$-71,390
Total Events$215,672$215,672$294,288$-78,616
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Interested-Person Transactions

Interested PartyRelationshipDescriptionShared RevenueAmount
David MandelkernDirectorManagement Advisory ServicesNo$120,000
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Other Long Term Liabilities$1,463,193
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
Yes
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section B, Line 11B

“Form 990 is prepared by an independent cpa firm in conjunction with the organization's director of finance. A draft of form 990 is reviewed by the director of finance, and corrections/modifications are made by the outside cpa. The revised draft is then reviewed by the director of finance. Any concerns are raised with the cpa firm and a consensus is achieved. Board members are sent a copy of the tax return prior to filing for their review. The return is then finalized and electronically filed with the taxing authorities.”

Form 990, Part VI, Section B, Line 12C

“The conflict of interest policy is presented and reviewed annually. Each board member is required to acknowledge in writing that no conflict exists.”

Form 990, Part VI, Section B, Line 15

“Compensation of the president of the organization was determined and approved by vote of the board of directors. Personnel of ucsf reviewed job requirements against technical abilities of subcontractors and determined whether or not they matched. All subcontractors were engaged at below-market rates.”

Form 990, Part VI, Section C, Line 19

“All governing documents, audited financial statements and form 990, return of organization exempt from income tax, are provided upon written request or through the quantum leap healthcare collaborative website, as well as to anyone who requests them in writing. They are also available for inspection at the qlhc office during normal business hours.”

Filing and Contact Details

Filer

Filer Name
Quantum Leap Healthcare Collaborative
EIN
20-4284925
Phone
8558660505
Address
580 CALIFORNIA STREET 1200, SAN FRANCISCO, CA 94104

Signing Officer

Name
Dan Dornbusch
Title
Interim CEO
Phone
8558660505
Signed
2025-11-17
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Daniel Dornbusch
Formed
2005
Legal Domicile
CA
Voting Board Members
12
Independent Board Members
11
Employees
114
Volunteers
15

Preparer

Firm
Armanino Advisory LLC
Address
2700 CAMINO RAMON STE 350, SAN RAMON, CA 94583-5004
Preparer
Matthew Petroski
Phone
9257902600
Supplemental Narrative

Financial Statement Notes

PART XI, LINE 2D - OTHER ADJUSTMENTS:

“Direct fundraising expenses 294,288.”

PART XII, LINE 2D - OTHER ADJUSTMENTS:

“Direct fundraising expenses 294,288.”

Raw XML AppendixShowing 400 of 859 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0ISPY 2.2 - I-SPY 2.2 USES A 'SEQUENTIAL MULTIPLE ASSIGNMENT RANDOMIZED TRIAL' (SMART) DESIGN - THAT IS BOTH SMART AND ADAPTIVE. THE TRIAL CONSISTS OF UP TO THREE BLOCKS OF TREATMENT. THE FIRST, BLOCK A, INCLUDES NOVEL TARGETED THERAPIES, WITHOUT STANDARD CHEMOTHERAPY. IF A PATIENT ACHIEVES A COMPLETE RESPONSE AFTER BLOCK A, THEY CAN AVOID TOXIC CHEMOTHERAPY AND GO DIRECTLY TO SURGERY. IF THEY HAVE RESIDUAL CANCER, OR THE TREATMENT IS FOUND TO HAVE LITTLE EFFECT HALFWAY THROUGH THE COURSE OF TREATMENT, THEY ARE RECOMMENDED TO PROCEED TO TREATMENT IN BLOCK B. IN BLOCK B, PATIENTS ARE ASSIGNED A TREATMENT REGIMEN MOST LIKELY TO WORK FOR THEIR SUBTYPE, OFTEN COMBINED WITH CHEMOTHERAPY SINCE THE RISK OF TOXICITY IS MORE ACCEPTABLE IN PATIENTS WITH MORE RESISTANT CANCER. (CONTINUED ON SCHEDULE O)IF BLOCK B TREATMENT IS EFFECTIVE, THE PATIENT CAN SKIP ADDITIONAL CHEMOTHERAPY AND GO TO SURGERY. ONLY IF THEY STILL HAVE TUMOR LEFT AFTER BLOCK B, WILL THE PATIENTT GET RESCUE THERAPY WITH DOXORUBICIN AND CYCLOPHOSPHAMIDE A CHEMOTHERAPY REGIMEN THAT HAS BEEN AROUND FOR DECADES. AVERAGE OVERHEAD BOOKED TO PROGRAM IN FY2024 = 36.9%
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IRS990/Form990PartVIISectionAGrp/TitleTxt1DIRECTOR, CO-FOUNDER
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IRS990/Form990PartVIISectionAGrp/TitleTxt4DIRECTOR
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IRS990/Form990PartVIISectionAGrp/TitleTxt6DIRECTOR
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IRS990/Form990PartVIISectionAGrp/TitleTxt11DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt12CEO
IRS990/Form990PartVIISectionAGrp/TitleTxt13VICE PRESIDENT OF FINANCE
IRS990/Form990PartVIISectionAGrp/TitleTxt14VICE PRES. STATISTICS (THRU 11/24)
IRS990/Form990PartVIISectionAGrp/TitleTxt15SR. VP, CLINICAL OPS & COMPLIANCE
IRS990/Form990PartVIISectionAGrp/TitleTxt16VP QUALITY ASSURANCE
IRS990/Form990PartVIISectionAGrp/TitleTxt17CHIEF DATA OFFICER
IRS990/Form990PartVIISectionAGrp/TitleTxt18VP BIOMARKER & INNOVATION
IRS990/Form990PartVIISectionAGrp/TitleTxt19DIRECTOR OF BIOMETRICS, ONCOLOGY
IRS990/Form990PartVIISectionAGrp/TitleTxt20DIRECTOR OF I-SPY COVID TRIAL
IRS990/Form990PartVIISectionAGrp/TitleTxt21CHIEF COLLABORATION OFFICER
IRS990/Form990PartVIISectionAGrp/TitleTxt22SR. DIRECTOR OF COLLABORATIONS
IRS990/Form990PartVIISectionAGrp/TitleTxt23EXECUTIVE DIRECTOR, DIVERSITY
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IRS990/MissionDesc0THE MISSION OF QUANTUM LEAP HEALTHCARE COLLARBORATIVE IS TO PROVIDE MANAGEMENT AND FINANCIAL SUPPORT TO HEALTHCARE RESEARCH ORGANIZATIONS, PARTICULARLY INVOLVING BREAST CANCER RESEARCH AND TREATMENT.
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