Liabilities / Assets
78th percentile
Higher debt load relative to assets than 78% of similar nonprofits.
Siviq Scores
Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.
0.60x
Liabilities / Revenue
Score unavailable
Liabilities-to-revenue requires both liabilities and revenue on this filing.
Net Margin
Score unavailable
Net margin requires both revenue and expenses on this filing.
Top Officer Pay
Score unavailable
This filing does not contain officer compensation rows.
Asset Growth
20th percentile
Faster asset growth than 20% of similar nonprofits.
Revenue Growth
Score unavailable
No valid filing value is available for this score.
Balance Sheet
Assets
Down$8,716,861
Down $351,832 (-3.9%) from 2012
Net Assets
Down$3,511,621
Down $453,261 (-11%) from 2012
Liabilities
Up$5,205,240
Up $101,429 (+2.0%) from 2012
Revenue And Expenses
Revenue
-
No earlier filing loaded for comparison.
Expenses
Down$9,349,630
Down $1,056,809 (-10%) from 2012
Net Income
-
No earlier filing loaded for comparison.
Historical Trend
Jump To
Filing Snapshot
- Filing Period
- Jul 1, 2012 to Jun 30, 2013
- Signed
- Feb 7, 2014
- Return Version
- 2012v2.1
- Gross Receipts
- $8,915,362
Mission and Program Overview
Mission
The critical path institute is a catalyst in the development of new approaches that advance medical innovation and regulatory science. This is achieved by leading teams that share data, knowledge and expertise resulting in sound, consensus based science.
Filing and Contact Details
Filer
- EIN
- 20-1991334
Raw XML AppendixShowing 400 of 944 raw XML fields
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990/ActivityOrMissionDescription | 0 | FOSTER AND CONDUCT RESEARCH AND EDUCATIONAL PROGRAMS THAT WILL LEAD TO SAFER MEDICAL PRODUCTS. |
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| IRS990/Description | 0 | THE CRITICAL PATH INSTITUTE (C-PATH) IS AN INDEPENDENT, NON-PROFIT ORGANIZATION UNIQUELY DEDICATED TO IMPLEMENTING THE FDA'S CRITICAL PATH INITIATIVE BY CREATING COLLABORATIONS AMONG REGULATORS (SCIENTISTS FROM THE FDA) AND THE REGULATED (MEDICAL PRODUCT INDUSTRY) THAT RESULT IN ACCELERATED DEVELOPMENT OF SAFE, NEW MEDICAL PRODUCTS. THE ACCOMPLISHMENTS FOR THIS FISCAL YEAR ARE SUMMARIZED BELOW.THE COALITION AGAINST MAJOR DISEASES (CAMD) WAS CREATED TO DEVELOP TOOLS AND PROCESSES TO ACCELERATE PROGRESS IN THE PREVENTION, TREATMENT AND CURE OF MAJOR NEURODEGENERATIVE DISEASES, INITIALLY FOCUSING ON ALZHEIMER'S AND PARKINSON'S DISEASES. ACCOMPLISHMENTS INCLUDE: 1) A PUBLIC DATABASE OF ALZHEIMER'S DISEASE CLINICAL TRIALS CONTINUES TO GROW IN SIZE AND USE. DATA FROM TWENTY FOUR CLINICAL TRIALS OF MEMBER COMPANIES COMPRISING 6,500 PATIENTS HAVE BEEN REMAPPED INTO THE NEW DATA STANDARD. THE DATABASE IS BEING USED BY NEARLY 250 SCIENTISTS FROM AROUND THE WORLD. 2) A DISEASE PROGRESSION MODEL CREATED FROM USE OF THE DATA FROM THE DATABASE, AND DATA FROM THE ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE STUDIES. THE MODEL, ALONG WITH A SIMULATION INFRASTRUCTURE, HAS BEEN FORMALLY ENDORSED BY THE FDA AND EMA FOR USE IN DESIGNING CLINICAL TRIALS FOR ALZHEIMER'S DISEASE. 3) A SERIES OF CEREBRAL SPINAL FLUID (CSF) AND HIPPOCAMPAL IMAGING BIOMARKERS WHICH HAVE BEEN STUDIED FOR USE IN IDENTIFYING EARLY SYMPTOMATIC PATIENTS WITH A HIGH LIKELIHOOD OF PROGRESSION TO DEMENTIA IN A SHORT PERIOD OF TIME. SUCH PATIENTS WOULD BE INCLUDED IN CLINICAL TRIALS OF THERAPIES FOR ALZHEIMER'S DISEASE. LOW HIPPOCAMPAL VOLUME HAS BEEN QUALIFIED BY THE EUROPEAN MEDICINES AGENCY (EMA), AND A RESEARCH PLAN FOR BOTH SETS OF BIOMARKERS HAS BEEN SUBMITTED TO THE FDA. CAMD MEMBERS HAVE MET WITH AND RECEIVED FEEDBACK FROM THE FDA, HAVE RESPONDED TO THEIR QUESTIONS AND ARE NOW EXECUTING THE RESEARCH PLAN. 4) THE CLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM (CDISC) STANDARD FOR PARKINSON'S DISEASE HAS BEEN DEVELOPED AND PUBLISHED AND IS AVAILABLE FOR USE. 5) AN UPDATED VERSION OF THE ALZHEIMER'S DISEASE CDISC STANDARD WAS DEVELOPED TO INCLUDE DATA ELEMENTS FOR PRE-DEMENTIA, ADDITIONAL COGNITIVE SCALES, AND ADDITIONAL BIOMARKERS. 6) A BRIEFING PACKAGE FOR SPECT IMAGING OF DOPAMINE TRANSPORT ACTIVITY FOR USE AS A CLINICAL TRIAL ENRICHMENT CRITERION FOR PARKINSON'S DISEASE HAS BEEN SUBMITTED TO THE FDA FOR ADVICE. 7) AN EFFORT HAS BEGUN TO DEVELOP AN IMPROVED CLINICAL OUTCOME ASSESSMENT INSTRUMENT FOR EARLY STAGES OF ALZHEIMER'S DISEASE.THE PATIENT-REPORTED OUTCOME CONSORTIUM (PRO) WAS CREATED TO IDENTIFY AND PRIORITIZE THE MEDICAL PRODUCT DEVELOPMENT AREAS WHERE PRO INSTRUMENTS ARE NEEDED, AS WELL AS TO SUBMIT QUALIFICATION DOSSIERS TO REGULATORY AGENCIES FOR QUALIFICATION OF PRO INSTRUMENTS FOR USE IN REGULATORY AND DRUG DEVELOPMENT DECISION MAKING. THE FOLLOWING WORKING GROUPS HAVE SUBMITTED BRIEFING DOSSIERS TO THE FDA THAT INCLUDE THEIR QUALITATIVE RESEARCH AND A DRAFT INSTRUMENT: COGNITION, IRRITABLE BOWEL SYNDROME, ASTHMA, AND DEPRESSION. TWO WORKING GROUPS, NON-SMALL CELL LUNG CANCER AND FUNCTIONAL DYSPEPSIA, HAVE SUBMITTED BRIEFING DOSSIERS TO THE FDA THAT INCLUDE THE RESULTS OF THEIR CONCEPT ELICITATION, THE PROTOCOL, AND THEIR STUDY DOCUMENTS, AS PART OF THE CONSULTATION AND ADVICE STAGE. RHEUMATOID ARTHRITIS IS COMPLETING THEIR GAP ANALYSIS AND LITERATURE REVIEW.THE PREDICTIVE SAFETY TESTING CONSORTIUM (PSTC) COMPILES, GENERATES, AND SUBMITS FOR REGULATORY REVIEW DATA ON NEW SAFETY BIOMARKERS TO BE USED IN DRUG DEVELOPMENT, THUS ADVANCING THE DRUG SAFETY ASSESSMENT PROCESS. THE NEPHROTOXICITY WORKING GROUP HAS SUBMITTED TWO IMPORTANT BRIEFING PACKAGES TO THE FDA AND EMA: ONE ON KIDNEY CLINICAL SAFETY BIOMARKERS WITH THE LEARNING-PHASE DATA FROM THE HEALTHY VOLUNTEER STUDY AND THE OTHER ON KIDNEY RODENT SAFETY BIOMARKERS FOR A FINAL EVALUATION. STUDIES TO MONITOR THE BIOMARKERS' PERFORMANCE IN PATIENTS WHO ARE ALREADY BEING MONITORED DUE TO NECESSARY TREATMENT W |
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| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 17 | 126599 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 18 | 367689 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 19 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 20 | 98516 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 21 | 139925 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 22 | 100109 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 23 | 30927 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 24 | 172772 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 25 | 242980 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 26 | 180595 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 27 | 166457 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 28 | 149258 |
| IRS990/Form990PartVIISectionA/ReportableCompFromOrganization | 29 | 148918 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 0 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 1 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 2 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 3 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 4 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 5 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 6 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 7 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 8 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 9 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 10 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 11 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 12 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 13 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 14 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 15 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 16 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 17 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 18 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 19 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 20 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 21 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 22 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 23 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 24 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 25 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 26 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 27 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 28 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 29 | 0 |
| IRS990/Form990PartVIISectionA/Title | 0 | BOARD MEMBER/ED, CPTR CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 1 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 2 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 3 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 4 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 5 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 6 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 7 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 8 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 9 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 10 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 11 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 12 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 13 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 14 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 15 | CHAIRMAN OF THE BOARD |
| IRS990/Form990PartVIISectionA/Title | 16 | VICE CHAIRMAN |
| IRS990/Form990PartVIISectionA/Title | 17 | PRESIDENT AND CEO THRU JAN 2012 |
| IRS990/Form990PartVIISectionA/Title | 18 | PRESIDENT AND CEO THRU FEB 2013 |
| IRS990/Form990PartVIISectionA/Title | 19 | PRESIDENT AND CEO AS OF FEB 2013 |
| IRS990/Form990PartVIISectionA/Title | 20 | SECRETARY/TREASURER TO SEP 2012 |
| IRS990/Form990PartVIISectionA/Title | 21 | SECRETARY AS OF NOV 2012 |
| IRS990/Form990PartVIISectionA/Title | 22 | TREASURER AS OF SEPT 2012 |
| IRS990/Form990PartVIISectionA/Title | 23 | COO THRU MAR 2012 |
| IRS990/Form990PartVIISectionA/Title | 24 | COO, TREASURER AS OF APR 2013 |
| IRS990/Form990PartVIISectionA/Title | 25 | ED, PSTC CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 26 | CHIEF SCIENCE OFFICER |
| IRS990/Form990PartVIISectionA/Title | 27 | ED, PRO CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 28 | ED, CAMD CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 29 | ED, CPTR CONSORTIUM |
| IRS990/Form990ProvidedToGoverningBody | 0 | 0 |
| IRS990/FormersListed | 0 | 0 |
| IRS990/FSAudited | 0 | 1 |
| IRS990/FSAuditedBasis/FinancialStatementSeparate | 0 | X |
| IRS990/FundraisingActivities | 0 | 0 |
| IRS990/FundsToPayPremiums | 0 | 0 |
| IRS990/GainOrLoss/Other | 0 | -2432 |
| IRS990/Gaming | 0 | 0 |
| IRS990/GovernmentGrants | 0 | 2165121 |
| IRS990/Grants | 0 | 778641 |
| IRS990/GrantsAndSimilarAmntsCY | 0 | 778641 |
| IRS990/GrantsAndSimilarAmntsPriorYear | 0 | 463426 |
| IRS990/GrantsToDomesticOrgs/ProgramServices | 0 | 778641 |
| IRS990/GrantsToDomesticOrgs/Total | 0 | 778641 |
| IRS990/GrantsToIndividuals | 0 | 0 |
| IRS990/GrantsToOrganizations | 0 | 1 |
| IRS990/GrantToRelatedPerson | 0 | 0 |
| IRS990/GrossAmountSalesAssets/Other | 0 | 550 |
| IRS990/GrossReceipts | 0 | 8915362 |
| IRS990/GrossRents/Real | 0 | 16322 |
| IRS990/GroupReturnForAffiliates | 0 | 0 |
| IRS990/Hospital | 0 | 0 |
| IRS990/IndependentAuditFinancialStmt | 0 | 1 |
| IRS990/IndoorTanningServices | 0 | 0 |
| IRS990/InfoInScheduleOPartIII | 0 | X |
| IRS990/InfoInScheduleOPartIX | 0 | X |
| IRS990/InfoInScheduleOPartVI | 0 | X |
| IRS990/InformationTechnology/Fundraising | 0 | 406 |
| IRS990/InformationTechnology/ManagementAndGeneral | 0 | 17845 |
| IRS990/InformationTechnology/ProgramServices | 0 | 129744 |
| IRS990/InformationTechnology/Total | 0 | 147995 |
| IRS990/Insurance/Fundraising | 0 | 233 |
| IRS990/Insurance/ManagementAndGeneral | 0 | 10232 |
| IRS990/Insurance/ProgramServices | 0 | 22756 |
| IRS990/Insurance/Total | 0 | 33221 |
| IRS990/InvestmentIncomeCurrentYear | 0 | 2525 |
| IRS990/InvestmentIncome/ExclusionAmount | 0 | 4957 |
| IRS990/InvestmentIncomePriorYear | 0 | 21292 |
| IRS990/InvestmentIncome/TotalRevenueColumn | 0 | 4957 |
| IRS990/InvestmentInJointVenture | 0 | 0 |
| IRS990/InvestmentsPubTradedSecurities/BOY | 0 | 3217568 |
| IRS990/InvestmentsPubTradedSecurities/EOY | 0 | 2403428 |
| IRS990/LandBldgEquipmentAccumDeprec | 0 | 730313 |
| IRS990/LandBuildingsEquipmentBasis | 0 | 906504 |
| IRS990/LandBuildingsEquipmentBasisNet/BOY | 0 | 328372 |
| IRS990/LandBuildingsEquipmentBasisNet/EOY | 0 | 176191 |
| IRS990/LessCostOthBasisSalesExpenses/Other | 0 | 2982 |
| IRS990/LessRentalExpenses/Real | 0 | 16011 |
| IRS990/LoanToOfficerOrDQP | 0 | 0 |
| IRS990/LobbyingActivities | 0 | 1 |
| IRS990/LocalChapters | 0 | 0 |
| IRS990/MaterialDiversionOrMisuse | 0 | 0 |
| IRS990/MembersOrStockholders | 0 | 0 |
| IRS990/MethodOfAccountingAccrual | 0 | X |
| IRS990/MinutesOfCommittees | 0 | 0 |
| IRS990/MinutesOfGoverningBody | 0 | 1 |
| IRS990/MissionDescription | 0 | THE CRITICAL PATH INSTITUTE IS A CATALYST IN THE DEVELOPMENT OF NEW APPROACHES THAT ADVANCE MEDICAL INNOVATION AND REGULATORY SCIENCE. THIS IS ACHIEVED BY LEADING TEAMS THAT SHARE DATA, KNOWLEDGE AND EXPERTISE RESULTING IN SOUND, CONSENSUS BASED SCIENCE. |
| IRS990/MoreThan5000KToIndividuals | 0 | 0 |
| IRS990/MoreThan5000KToOrganizations | 0 | 0 |
| IRS990/NameOfPrincipalOfficerPerson | 0 | MARTHA BRUMFIELD PHD |
| IRS990/NbrIndependentVotingMembers | 0 | 12 |
Document Assets
No mirrored PDF or thumbnail assets are attached yet.
Filings
Displayed year
2013 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.
- Assets
- $8,716,861
- Liabilities
- $5,205,240
- Net assets
- $3,511,621
- Revenue
- -
- Expenses
- $9,349,630
- Net income
- -