Liabilities / Assets
73rd percentile
Higher debt load relative to assets than 73% of similar nonprofits.
Siviq Scores
Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.
0.56x
Liabilities / Revenue
Score unavailable
Liabilities-to-revenue requires both liabilities and revenue on this filing.
Net Margin
Score unavailable
Net margin requires both revenue and expenses on this filing.
Top Officer Pay
Score unavailable
This filing does not contain officer compensation rows.
Asset Growth
75th percentile
Faster asset growth than 75% of similar nonprofits.
Revenue Growth
Score unavailable
No valid filing value is available for this score.
Balance Sheet
Assets
Up$9,068,693
Up $858,799 (+10%) from 2011
Net Assets
Up$3,964,882
Up $195,405 (+5.2%) from 2011
Liabilities
Up$5,103,811
Up $663,394 (+15%) from 2011
Revenue And Expenses
Revenue
-
No earlier filing loaded for comparison.
Expenses
Up$10,406,439
Up $1,241,530 (+14%) from 2011
Net Income
-
No earlier filing loaded for comparison.
Historical Trend
Jump To
Filing Snapshot
- Filing Period
- Jul 1, 2011 to Jun 30, 2012
- Signed
- Mar 22, 2013
- Return Version
- 2011v1.5
- Gross Receipts
- $10,603,212
Mission and Program Overview
Mission
The critical path institute is a catalyst in the development of new approaches that advance medical innovation and regulatory science. This is achieved by leading teams that share data, knowledge and expertise resulting in sound, consensus based science.
Filing and Contact Details
Filer
- EIN
- 20-1991334
Raw XML AppendixShowing 400 of 903 raw XML fields
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990/ActivityOrMissionDescription | 0 | FOSTER AND CONDUCT RESEARCH AND EDUCATIONAL PROGRAMS THAT WILL LEAD TO SAFER MEDICAL PRODUCTS. |
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| IRS990/Description | 0 | THE CRITICAL PATH INSTITUTE (C-PATH) IS AN INDEPENDENT, NON-PROFIT ORGANIZATION UNIQUELY DEDICATED TO IMPLEMENTING THE FDA'S CRITICAL PATH INITIATIVE BY CREATING COLLABORATIONS AMONG REGULATORS (SCIENTISTS FROM THE FDA) AND THE REGULATED (MEDICAL PRODUCT INDUSTRY) THAT RESULT IN ACCELERATED DEVELOPMENT OF SAFE, NEW MEDICAL PRODUCTS. THE ACCOMPLISHMENTS FOR THIS FISCAL YEAR REPORT INCLUDE:THE COALITION AGAINST MAJOR DISEASES (CAMD) WAS CREATED TO DEVELOP TOOLS AND PROCESSES TO ACCELERATE PROGRESS IN THE PREVENTION, TREATMENT AND CURE OF MAJOR NEURODEGENERATIVE DISEASES, INITIALLY FOCUSING ON ALZHEIMER'S AND PARKINSON'S DISEASES. ACCOMPLISHMENTS INCLUDE: 1) ITS PUBLIC DATABASE OF ALZHEIMER'S DISEASE CLINICAL TRIALS CONTINUES TO GROW IN SIZE AND USE. DATA FROM TWENTY FOUR CLINICAL TRIALS OF MEMBER COMPANIES COMPRISING 6,500 PATIENTS HAVE BEEN REMAPPED INTO THE NEW DATA STANDARD. THE DATABASE IS BEING USED BY NEARLY 250 SCIENTISTS FROM AROUND THE WORLD. 2) USING THE DATA FROM THAT DATABASE, AND DATA FROM THE ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE STUDIES, AN ALZHEIMER'S DISEASE PROGRESSION MODEL HAS BEEN CREATED. THE MODEL, ALONG WITH A SIMULATION INFRASTRUCTURE, HAS BEEN SUBMITTED TO THE FDA FOR A FORMAL REGULATORY DECISION ON ITS FIT FOR PURPOSE IN DESIGNING CLINICAL TRIALS FOR ALZHEIMER'S DISEASE. 3) A SERIES OF CEREBRAL SPINAL FLUID (CSF) AND HIPPOCAMPAL IMAGING BIOMARKERS HAVE BEEN IDENTIFIED AS POTENTIALLY USEFUL IN IDENTIFYING EARLY SYMPTOMATIC PATIENTS WITH A HIGH LIKELIHOOD OF CONVERSION TO FULL DEMENTIA IN A SHORT PERIOD OF TIME FOR INCLUSION IN CLINICAL TRIALS. LOW HIPPOCAMPAL VOLUME HAS BEEN QUALIFIED BY THE EUROPEAN MEDICINES AGENCY (EMA) FOR USE IN ENRICHING ALZHEIMER'S DISEASE CLINICAL TRIALS. A RESEARCH PLAN FOR BOTH SETS OF BIOMARKERS HAS BEEN WRITTEN AND SUBMITTED TO THE FDA. CAMD MEMBERS HAVE MET WITH THE FDA AND RECEIVED FEEDBACK FROM THE FDA AND HAVE RESPONDED TO THEIR QUESTIONS. THE PLANS ARE BEING EXECUTED NOW. 4) A DRAFT OF THE CLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM (CDISC) STANDARDS FOR PARKINSON'S DISEASE HAS BEEN DEVELOPED AND PUBLISHED AND IS AVAILABLE FOR USE. 5) A BRIEFING PACKAGE FOR SPECT IMAGING OF DOPAMINE TRANSPORT ACTIVITY FOR USE AS A CLINICAL TRIAL ENRICHMENT CRITERIA FOR PARKINSON'S DISEASE HAS BEEN WRITTEN AND IS BEING REVIEWED IN PREPARATION FOR SUBMISSION TO THE FDA. 6) AN EFFORT HAS BEGUN TO DEVELOP AN IMPROVED CLINICAL OUTCOME ASSESSMENT INSTRUMENT FOR EARLY STAGES OF ALZHEIMER'S DISEASE.THE PATIENT-REPORTED OUTCOMES CONSORTIUM (PRO) WAS CREATED TO IDENTIFY AND PRIORITIZE THE MEDICAL PRODUCT DEVELOPMENT AREAS WHERE PRO INSTRUMENTS ARE NEEDED, ESTABLISH QUALIFICATION DOSSIERS TO REGULATORY AGENCIES FOR QUALIFICATION OF PRO INSTRUMENTS FOR USE IN REGULATORY AND DEVELOPMENTAL DECISION MAKING. THE FOLLOWING WORKING GROUPS HAVE SUBMITTED SCOPING STAGE SUMMARY DOCUMENTS TO THE FDA: COGNITION, IRRITABLE BOWEL SYNDROME, ASTHMA, DEPRESSION, NON-SMALL CELL LUNG CANCER, RHEUMATOID ARTHRITIS, AND FUNCTIONAL DYSPEPSIA. ALL HAVE BEEN SUCCESSFULLY REVIEWED. ALL WORKING GROUPS EXCEPT FUNCTIONAL DYSPEPSIA ARE EXECUTING THEIR QUALITATIVE RESEARCH. THE FUNCTIONAL DYSPEPSIA WORKING GROUP IS IN THE FINAL STAGES OF EXECUTING THEIR CONTRACT WITH THE SELECTED CONTRACT RESEARCH ORGANIZATION (CRO). THE COGNITION WORKING GROUP IS REVIEWING THE RESULTS OF THE QUALITATIVE RESEARCH AND IS IN THE PROCESS OF CONTRACTING THE QUANTITATIVE ANALYSIS OF THE DRAFT INSTRUMENT. FULL PSYCHOMETRIC TESTING OF THE INSTRUMENT WILL FOLLOW THAT.THE PREDICTIVE SAFETY TESTING CONSORTIUM (PSTC) COMPILES, GENERATES, AND SUBMITS FOR REGULATORY REVIEW DATA ON NEW SAFETY BIOMARKERS TO BE USED IN DRUG DEVELOPMENT, THUS ADVANCING THE DRUG SAFETY ASSESSMENT PROCESS. THE HEPATOTOXICITY, NEPHROTOXICITY, AND SKELETAL MUSCLE WORKING GROUPS HAVE COMPLETED NEARLY 100 STUDIES AND LOADED THE DATA INTO THE DATABASE FOR ANALYSIS. ALL THREE WORKING GROUPS HAVE SUBMITTED A BRIEFING PACKAGE TO THE FDA FOR REVIEW. THESE THREE WORKING GROUPS HAV |
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| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 12 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 13 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 14 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 15 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 16 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 17 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 18 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 19 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 20 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 21 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 22 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 23 | 0 |
| IRS990/Form990PartVIISectionA/ReportableCompFromRelatedOrgs | 24 | 0 |
| IRS990/Form990PartVIISectionA/Title | 0 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 1 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 2 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 3 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 4 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 5 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 6 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 7 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 8 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 9 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 10 | BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 11 | CHAIRMAN OF THE BOARD |
| IRS990/Form990PartVIISectionA/Title | 12 | VICE CHAIRMAN |
| IRS990/Form990PartVIISectionA/Title | 13 | PRESIDENT AND CEO (THRU JAN 2012) |
| IRS990/Form990PartVIISectionA/Title | 14 | PRESIDENT AND CEO (AS OF FEB 2012) |
| IRS990/Form990PartVIISectionA/Title | 15 | SECRETARY (THRU SEP 2011)/BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 16 | TREASURER/SECRETARY (AS OF SEP 2011) |
| IRS990/Form990PartVIISectionA/Title | 17 | COO (THRU JAN 2012)/BOARD MEMBER |
| IRS990/Form990PartVIISectionA/Title | 18 | COO (AS OF MARCH 2012) |
| IRS990/Form990PartVIISectionA/Title | 19 | CFO (AS OF JUN 2012) |
| IRS990/Form990PartVIISectionA/Title | 20 | CHIEF TECHNOLOGY OFFICER, ABL |
| IRS990/Form990PartVIISectionA/Title | 21 | EDUCATION DIRECTOR |
| IRS990/Form990PartVIISectionA/Title | 22 | ED, CAMD CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 23 | ED, PSTC CONSORTIUM |
| IRS990/Form990PartVIISectionA/Title | 24 | ED, PRO CONSORTIUM |
| IRS990/Form990ProvidedToGoverningBody | 0 | 0 |
| IRS990/FormersListed | 0 | 0 |
| IRS990/FSAudited | 0 | 1 |
| IRS990/FundraisingActivities | 0 | 0 |
| IRS990/FundsToPayPremiums | 0 | 0 |
| IRS990/GainOrLoss/Other | 0 | -1368 |
| IRS990/Gaming | 0 | 0 |
| IRS990/GovernmentGrants | 0 | 2892775 |
| IRS990/Grants | 0 | 463429 |
| IRS990/GrantsAndSimilarAmntsCY | 0 | 463426 |
| IRS990/GrantsAndSimilarAmntsPriorYear | 0 | 320561 |
| IRS990/GrantsToDomesticOrgs/ProgramServices | 0 | 463426 |
| IRS990/GrantsToDomesticOrgs/Total | 0 | 463426 |
| IRS990/GrantsToIndividuals | 0 | 0 |
| IRS990/GrantsToOrganizations | 0 | 1 |
| IRS990/GrantToRelatedPerson | 0 | 0 |
| IRS990/GrossReceipts | 0 | 10603212 |
| IRS990/GroupReturnForAffiliates | 0 | 0 |
| IRS990/Hospital | 0 | 0 |
| IRS990/IndependentAuditFinancialStmt | 0 | 1 |
| IRS990/IndoorTanningServices | 0 | 0 |
| IRS990/InfoInScheduleOPartIII | 0 | X |
| IRS990/InfoInScheduleOPartVI | 0 | X |
| IRS990/InformationTechnology/Fundraising | 0 | 464 |
| IRS990/InformationTechnology/ManagementAndGeneral | 0 | 8915 |
| IRS990/InformationTechnology/ProgramServices | 0 | 200679 |
| IRS990/InformationTechnology/Total | 0 | 210058 |
| IRS990/Insurance/Fundraising | 0 | 640 |
| IRS990/Insurance/ManagementAndGeneral | 0 | 12313 |
| IRS990/Insurance/ProgramServices | 0 | 27571 |
| IRS990/Insurance/Total | 0 | 40524 |
| IRS990/InvestmentIncomeCurrentYear | 0 | 21292 |
| IRS990/InvestmentIncome/ExclusionAmount | 0 | 22660 |
| IRS990/InvestmentIncomePriorYear | 0 | 16840 |
| IRS990/InvestmentIncome/TotalRevenueColumn | 0 | 22660 |
| IRS990/InvestmentInJointVenture | 0 | 0 |
| IRS990/InvestmentsPubTradedSecurities/BOY | 0 | 3346595 |
| IRS990/InvestmentsPubTradedSecurities/EOY | 0 | 3217568 |
| IRS990/LandBldgEquipmentAccumDeprec | 0 | 581933 |
| IRS990/LandBuildingsEquipmentBasis | 0 | 910305 |
| IRS990/LandBuildingsEquipmentBasisNet/BOY | 0 | 460501 |
| IRS990/LandBuildingsEquipmentBasisNet/EOY | 0 | 328372 |
| IRS990/LessCostOthBasisSalesExpenses/Other | 0 | 1368 |
| IRS990/LoanToOfficerOrDQP | 0 | 0 |
| IRS990/LobbyingActivities | 0 | 1 |
| IRS990/LocalChapters | 0 | 0 |
| IRS990/MaterialDiversionOrMisuse | 0 | 0 |
| IRS990/MembersOrStockholders | 0 | 0 |
| IRS990/MethodOfAccountingAccrual | 0 | X |
| IRS990/MinutesOfCommittees | 0 | 0 |
| IRS990/MinutesOfGoverningBody | 0 | 1 |
| IRS990/MissionDescription | 0 | TO IMPROVE HUMAN HEALTH AND WELL-BEING BY DEVELOPING NEW TECHNOLOGIES AND METHODS TO ACCELERATE THE DEVELOPMENT AND REVIEW OF MEDICAL PRODUCTS. |
| IRS990/MoreThan5000KToIndividuals | 0 | 0 |
| IRS990/MoreThan5000KToOrganizations | 0 | 0 |
| IRS990/NameOfPrincipalOfficerPerson | 0 | CAROLYN COMPTON MD PHD |
| IRS990/NbrIndependentVotingMembers | 0 | 13 |
| IRS990/NbrVotingGoverningBodyMembers | 0 | 15 |
| IRS990/NbrVotingMembersGoverningBody | 0 | 15 |
| IRS990/NetAssetsOrFundBalancesBOY | 0 | 3769477 |
| IRS990/NetAssetsOrFundBalancesEOY | 0 | 3964882 |
| IRS990/NetGainOrLossInvestments/ExclusionAmount | 0 | -1368 |
| IRS990/NetGainOrLossInvestments/TotalRevenueColumn | 0 | -1368 |
| IRS990/NetUnrelatedBusinessTxblIncome | 0 | 0 |
| IRS990/NoncashContributions | 0 | 1064 |
| IRS990/NonDeductibleContributions | 0 | 0 |
| IRS990/NumberFormsTransmittedWith1096 | 0 | 47 |
| IRS990/NumberIndependentVotingMembers | 0 | 13 |
| IRS990/NumberIndividualsGT100K | 0 | 16 |
| IRS990/NumberOfContractorsGT100K | 0 | 10 |
| IRS990/NumberOfEmployees | 0 | 73 |
| IRS990/NumberW2GIncluded | 0 | 0 |
| IRS990/Occupancy/Fundraising | 0 | 6236 |
| IRS990/Occupancy/ManagementAndGeneral | 0 | 213457 |
| IRS990/Occupancy/ProgramServices | 0 | 214483 |
| IRS990/Occupancy/Total | 0 | 434176 |
| IRS990/OfficeExpenses/Fundraising | 0 | 3889 |
| IRS990/OfficeExpenses/ManagementAndGeneral | 0 | 51337 |
| IRS990/OfficeExpenses/ProgramServices | 0 | 205261 |
| IRS990/OfficeExpenses/Total | 0 | 260487 |
| IRS990/OfficerEntityWithBsnssRltnshp | 0 | 0 |
| IRS990/OfficerMailingAddress | 0 | 0 |
| IRS990/Organization501c3 | 0 | X |
| IRS990/OtherAssetsTotal/BOY | 0 | 27141 |
| IRS990/OtherAssetsTotal/EOY | 0 | 27141 |
| IRS990/OtherEmployeeBenefits/Fundraising | 0 | 6032 |
| IRS990/OtherEmployeeBenefits/ManagementAndGeneral | 0 | 88472 |
| IRS990/OtherEmployeeBenefits/ProgramServices | 0 | 242821 |
| IRS990/OtherEmployeeBenefits/Total | 0 | 337325 |
| IRS990/OtherExpensePriorYear | 0 | 3531836 |
| IRS990/OtherExpensesCurrentYear | 0 | 4187345 |
| IRS990/OtherExpenses/Description | 0 | MISCELLANEOUS |
| IRS990/OtherExpenses/Description | 1 | DUES AND SUBSCRIPTIONS |
| IRS990/OtherExpenses/Fundraising | 0 | 713 |
| IRS990/OtherExpenses/Fundraising | 1 | 494 |
| IRS990/OtherExpenses/ManagementAndGeneral | 0 | 1968 |
Document Assets
No mirrored PDF or thumbnail assets are attached yet.
Filings
Displayed year
2012 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.
- Assets
- $9,068,693
- Liabilities
- $5,103,811
- Net assets
- $3,964,882
- Revenue
- -
- Expenses
- $10,406,439
- Net income
- -