Civic Intelligence

Alfred E Mann Foundation For

EIN 95-4002032 • 501(c)3 • Santa Clarita, CA

View Organization Page

Profile

The alfred mann foundation is a medical research organization dedicated to bringing advanced medical technologies to the public to provide significant improvements to the health, security and quality of life for people suffering from debilitating medical conditions.

25134 Rye Canyon LoopSanta Clarita, CA 91355

www.aemf.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

10th percentile

0.02x

Higher debt load relative to assets than 10% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2025

Liabilities / Revenue

39th percentile

0.35x

Higher debt load relative to revenue than 39% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2025

Net Margin

1st percentile

-130%

Higher net margin than 1% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2025

Top Officer Pay

Score unavailable

No value available

No filing with officer rows is available for this organization yet.

Asset Growth

12th percentile

-5.1%

Faster asset growth than 12% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Annualized from 2024 to 2025

Revenue Growth

2nd percentile

-59%

Faster revenue growth than 2% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Annualized from 2024 to 2025

Balance Sheet
Liabilities / Assets10th percentile

Assets

Down

$353,361,768

Down $19,176,088 (-5.1%) from 2024

Liabilities

Down

$6,385,007

Down $284,948 (-4.3%) from 2024

Net Assets

Down

$346,976,761

Down $18,891,140 (-5.2%) from 2024

Operations
Liabilities / Revenue39th percentileNet Margin1st percentile

Revenue

Down

$18,144,382

Down $26,002,877 (-59%) from 2024

Expenses

Up

$41,776,524

Up $9,931,588 (+31%) from 2024

Net Income

Down

-$23,632,142

Down $35,934,465 (-292%) from 2024

Trend Graphs

Balance Sheet Trend

Asset Growth12th percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$400M$300M$200M$100M$0Assets 2011: $149,147,272Liabilities 2011: $15,477,095Net Assets 2011: $133,670,1772011Assets 2012: $127,153,690Liabilities 2012: $14,940,475Net Assets 2012: $112,213,2152012Assets 2013: $121,867,281Liabilities 2013: $15,413,443Net Assets 2013: $106,453,8382013Assets 2014: $114,740,000Liabilities 2014: $11,197,787Net Assets 2014: $103,542,2132014Assets 2015: $108,633,540Liabilities 2015: $15,219,334Net Assets 2015: $93,414,2062015Assets 2016: $82,113,434Liabilities 2016: $8,156,995Net Assets 2016: $73,956,4392016Assets 2017: $63,522,432Liabilities 2017: $1,651,881Net Assets 2017: $61,870,5512017Assets 2018: $50,020,916Liabilities 2018: $656,801Net Assets 2018: $49,364,1152018Assets 2019: $93,529,351Liabilities 2019: $7,095,338Net Assets 2019: $86,434,0132019Assets 2020: $59,071,014Liabilities 2020: $11,490,776Net Assets 2020: $47,580,2382020Assets 2021: $307,411,437Liabilities 2021: $2,731,424Net Assets 2021: $304,680,0132021Assets 2022: $374,343,975Liabilities 2022: $2,647,791Net Assets 2022: $371,696,1842022Assets 2023: $344,680,217Liabilities 2023: $5,996,723Net Assets 2023: $338,683,4942023Assets 2024: $372,537,856Liabilities 2024: $6,669,955Net Assets 2024: $365,867,9012024Assets 2025: $353,361,768Liabilities 2025: $6,385,007Net Assets 2025: $346,976,7612025

Highlighted filing

2025

Assets$353,361,768
Liabilities$6,385,007
Net Assets$346,976,761
Open 2025 Filing

Operations Trend

Revenue Growth2nd percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$300M$200M$100M$0-$100MExpenses 2011: $21,995,3702011Expenses 2012: $24,699,7402012Expenses 2013: $22,317,5392013Revenue 2014: $19,639,842Expenses 2014: $24,203,179Net Income 2014: -$4,563,3372014Revenue 2015: $7,594,704Expenses 2015: $17,902,645Net Income 2015: -$10,307,9412015Revenue 2016: $4,540,535Expenses 2016: $17,253,210Net Income 2016: -$12,712,6752016Revenue 2017: $986,677Expenses 2017: $15,345,907Net Income 2017: -$14,359,2302017Revenue 2018: $431,624Expenses 2018: $13,081,377Net Income 2018: -$12,649,7532018Revenue 2019: $334,706Expenses 2019: $8,041,139Net Income 2019: -$7,706,4332019Revenue 2020: $2,312,474Expenses 2020: $13,859,108Net Income 2020: -$11,546,6342020Revenue 2021: $225,963,433Expenses 2021: $22,418,205Net Income 2021: $203,545,2282021Revenue 2022: $128,538,828Expenses 2022: $18,142,697Net Income 2022: $110,396,1312022Revenue 2023: $31,054,042Expenses 2023: $22,822,234Net Income 2023: $8,231,8082023Revenue 2024: $44,147,259Expenses 2024: $31,844,936Net Income 2024: $12,302,3232024Revenue 2025: $18,144,382Expenses 2025: $41,776,524Net Income 2025: -$23,632,1422025

Highlighted filing

2025

Revenue$18,144,382
Expenses$41,776,524
Net Income-$23,632,142
Open 2025 Filing

Filings

Most recent year

2025 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.

Open filing
Assets
$353,361,768
Liabilities
$6,385,007
Net assets
$346,976,761
Revenue
$18,144,382
Expenses
$41,776,524
Net income
-$23,632,142
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2025Facts available. Structured filing facts are available, but richer extracted sections are limited.$353$6.39$347$18.1$41.8$23.6
2024XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$373$6.67$366$44.1$31.8$12.3
2023Facts available. Structured filing facts are available, but richer extracted sections are limited.$345$6.00$339$31.1$22.8$8.23
2022Facts available. Structured filing facts are available, but richer extracted sections are limited.$374$2.65$372$129$18.1$110
2021Facts available. Structured filing facts are available, but richer extracted sections are limited.$307$2.73$305$226$22.4$204
2020Facts available. Structured filing facts are available, but richer extracted sections are limited.$59.1$11.5$47.6$2.31$13.9$11.5
2019Summary only. Only limited summary data is available for this year.$93.5$7.10$86.4$0.33$8.04$7.71
2018XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$50.0$0.66$49.4$0.43$13.1$12.6
2017XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$63.5$1.65$61.9$0.99$15.3$14.4
2016XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$82.1$8.16$74.0$4.54$17.3$12.7
2015Detailed filing. Detailed filing data is available for this year.$109$15.2$93.4$7.59$17.9$10.3
2014Detailed filing. Detailed filing data is available for this year.$115$11.2$104$19.6$24.2$4.56
2013Facts available. Structured filing facts are available, but richer extracted sections are limited.$122$15.4$106$22.3
2012Facts available. Structured filing facts are available, but richer extracted sections are limited.$127$14.9$112$24.7
2011Facts available. Structured filing facts are available, but richer extracted sections are limited.$149$15.5$134$22.0
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Apr 1, 2024 to Mar 31, 2025
Signed
Aug 4, 2025
Return Version
2024v5.2
Gross Receipts
$57,137,773
Mission and Program Overview

Mission

The alfred mann foundation is a medical research organization dedicated to bringing advanced medical technologies to the public to provide significant improvements to the health, security and quality of life for people suffering from debilitating medical conditions.

Conduct medical and scientific research

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$195,028,530$194,030,607▼ $997,923
Savings and Temporary Cash Investments$116,082,439$88,774,317▼ $27,308,122
Investments Other Securities$49,977,919$61,869,909▲ $11,891,990
Land, Buildings, and Equipment, Net$3,255,116$4,469,669▲ $1,214,553
Intangible Assets$1,004,764$1,062,425▲ $57,661
Cash and Non-Interest-Bearing Accounts$3,936,641$602,819▼ $3,333,822
Prepaid Expenses and Deferred Charges$258,166$296,888▲ $38,722
Accounts Receivable$1,225$0▼ $1,225
Total Assets$372,537,856$353,361,768▼ $19,176,088
Other Assets Total$2,993,056$2,255,134▼ $737,922
Liabilities
Accounts Payable and Accrued Expenses$3,970,204$4,289,806▲ $319,602
Other Liabilities$2,699,751$2,095,201▼ $604,550
Total Liabilities$6,669,955$6,385,007▼ $284,948
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$365,867,901$346,976,761▼ $18,891,140
Total Net Assets Fund Balance$365,867,901$346,976,761▼ $18,891,140
Total Liabilities and Net Assets / Fund Balance$372,537,856$353,361,768▼ $19,176,088

Asset Categories

AssetBook ValueDepreciationBasis
Equipment$3,809,755$5,118,076$8,927,831
Other Land Buildings$255,601$1,428,970$1,684,571
Leasehold Improvements$404,313$1,133,713$1,538,026
Other Securities$1,910,729--
Compensation and Service Providers
Top Officer PayScore unavailable

Employees

NameTitleFull / Part TimeBaseOtherTotal
Robert GreenbergCEO/president/chair of the BoardFT$586,299$735,842$1,322,141
Farah BoroomandChief Financial Officer/treasurerFT$323,038$251,760$574,798
Corey DishmonChief Business and Legal OfficerFT$329,036$98,890$427,926
John RiveraVice President, Product DevelopmentFT$297,355$92,324$389,679
Neil TalbotVP, Research and TechnologyFT$264,743$96,379$361,122
Shawn LewisVice President, Human ResourcesFT$277,247$80,322$357,569
Cedric NavarroV.p. Quality Assurance, Reg. Affairs, InterimFT$283,665$53,331$336,996
Cedric NavarroV.p. Quality Assurance, Reg. Affairs-$248,665$88,331$336,996
Carl BuiceSenior Director, Project ManagementFT$243,841$80,904$324,745
Brian MechVP, StrategyFT$277,507$39,277$316,784
Valma KleinVP, Clinical AffairsFT$210,791$95,716$306,507
Philip LeeSecretary/assistant General CounselFT$190,982$65,153$256,135

Board Members and Trustees

NameTitle
David GillBoard Member
Heather PageBoard Member
Ken WeatherwaxBoard Member
Richard WaughBoard Member

Highest Paid Contractors

ContractorServicesLocationCompensation
Morgan Lewis & Bockius LLPLegal Services1701 MARKET STREET, Philadelphia, PA 19103$3,758,302
Stuart Karten Design (dba Karten DesignR&d Consultants4204 GLENCOE AVENUE, Marina Del Rey, CA 90292$595,720
Medix Staffing Solutions INCSoftware Consultants222 S RIVERSIDE PLAZA SUITE 2120, Chicago, IL 60606$396,451
Lewis Roca Rothgerber Christie LLPLegal Services (patents)201 EAST WASHINGTON STREET, Phoenix, AZ 85004$320,656
Ubs Investment ManagementInvestment Management Fees299 PARK AVENUE, New York, NY 10171$309,937
Revenue and Support

Revenue Composition

Contributions and Grants
$378
Program Service Revenue
$420,079
Investment Income
$14,822,058
Other Revenue
$2,901,867
All Other Contributions
$378
Change in Net Assets
$-23,632,142

Audited Revenue Reconciliation

Revenue per Audited Statements
$18,144,382
Revenue Not Reported on Financial Statements
$0
Revenue Not Reported on Form 990
$4,741,002
Total Revenue per Audited Statements
$22,885,384
Total Revenue per Form 990
$18,144,382
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Salaries, Compensation, and Employee Benefits$21,161,843
Other Expenses$20,604,681
Grants and Similar Amounts Paid$10,000
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$12,630,345$1,697,166-$14,327,511
Fees for Services Legal$8,590,486$238,474-$8,828,960
Fees for Services Other$3,976,059$115,073-$4,091,132
Current Officers, Directors, Trustees, and Key Employees$2,674,495$873,872-$3,548,367
Office Expenses$2,263,341$117,369-$2,380,710
Other Employee Benefits$1,555,851$158,895-$1,714,746
Occupancy$1,253,956$171,077-$1,425,033
Fees for Service Investment Mgmnt Fees-$1,212,875-$1,212,875
Payroll Taxes$1,006,689$132,004-$1,138,693
Depreciation Depletion$1,026,186$93,151-$1,119,337
Information Technology$607,753$12,863-$620,616
Pension Plan Contributions$380,911$51,615-$432,526
Travel$182,477$34,294-$216,771
Insurance$126,321$16,381-$142,702
Fees for Services Accounting-$115,214-$115,214
Conferences and Meetings$82,603$31,134-$113,737
Other Expenses$13,266$2,616-$15,882
Grants to Domestic Orgs$10,000--$10,000
Total Functional Expenses$36,564,880$5,211,644$0$41,776,524

Audited Expense Reconciliation

Line ItemAmount
Expenses per Audited Statements$41,776,524
Total Expenses per Audited Statements$41,776,524
Total Expenses per Form 990$41,776,524
Expenses Not Reported on Financial Statements$0
Expenses Not Reported on Form 990$0
International Activity

International Summary

Offices
0
Employees
4
Spending
$29,323,846

International Compliance

Activity in boycott countries
No
Foreign corporation ownership
Yes
Foreign partnership interest
Yes
Interest in foreign trust
No
Passive foreign investment company interest
Yes
Transfers to foreign corporations
Yes

International Activities

RegionActivityServicesOfficesEmployeesSpending
Central America and the CaribbeanInvestmentsR&d Software Services00$28,807,085
South AsiaProgram ServicesClinical Research01$323,509
North AmericaProgram Services-00$111,700
Europe (including Iceland & Greenland)Program ServicesSoftware Services02$78,081
North AmericaInvestmentsSoftware Services00$3,150
Central America and the CaribbeanProgram Services-01$321
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Operating Lease Liabilities$2,095,201
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section B, Line 11B

“A draft of the 990 will be presented by management to the audit committee of the board of directors for their review and discussion. A full copy of the form will be provided to all voting members prior to filing with the irs.”

Form 990, Part VI, Section B, Line 12C

“Conflict of interest disclosures are updated annually and potential conflicts are reviewed prior to participating in transactions. If a conflict exists, the person with a conflict does not vote.”

Form 990, Part VI, Section B, Line 15

“The board of directors reviews and approves the compensation of the ceo and his direct reports including the cfo. It also reviews and approves the overall annual adjustments to compensation of other employees. Specific adjustments for other employees are handled by the ceo and head of human resources using comparisons to salary surveys for similar positions and experience. The board of directors approved compensation for the ceo and his direct reports including the cfo on 3/13/2025. This process was documented and used detailed information and analysis from an independent national executive compensation analysis firm.”

Form 990, Part VI, Section C, Line 19

“Members of the public or interested parties may request to review or recieve a copy of the governing documents, conflict of interest policy, and financial statements by phone or mail.”

Filing and Contact Details

Filer

Filer Name
The Alfred E Mann Foundation for
EIN
95-4002032
Phone
6617026700
Address
25134 RYE CANYON LOOP, SANTA CLARITA, CA 91355
Doing Business As
Humannity Medtec

Signing Officer

Name
Robert Greenberg
Title
CEO
Phone
6617026700
Signed
2025-08-04
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Robert Greenberg
Formed
1985
Legal Domicile
CA
Voting Board Members
5
Independent Board Members
4
Employees
137
Volunteers
5

Preparer

Firm
Baker Tilly Advisory Group Lp
Address
21700 OXNARD ST STE 300, WOODLAND HILLS, CA 91367
Preparer
Wendy Campos
Phone
8185771900
Supplemental Narrative

Financial Statement Notes

PART X, LINE 2:

“The alfred e. Mann foundation for scientific research is exempt from federal income and california franchise taxes under section 501(c)(3) of the internal revenue code and the corresponding california provisions. The alfred e. Mann foundation for scientific research had no significant unrelated business income tax during the year ended march 31, 2025. Accordingly, no tax provision for unrelated business income has been made in the accompanying financial statements for the year ended march 31, 2024 and 2025. The foundation, under the provisions of asc 740, income taxes, had no uncertain tax positions requiring accrual as of march 31, 2024 and 2025.”

Raw XML AppendixShowing 400 of 811 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

Path#Value
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IRS990/Desc0NEUROMODULATION SYSTEMADVANCED IMPLANTABLE NEUROMODULATION SYSTEM DEVELOPMENT:THIS PROGRAM COVERS (A) THE MONITORING AND EVALUATION OF SEVERAL EARLY-STAGE ADVANCED RESEARCH AND DEVELOPMENT EFFORTS UNDERWAY THAT ARE DIRECTED AT DEVELOPING INNOVATIVE TECHNOLOGIES, PROJECT IDEAS AND CONCEPTS BEFORE THEY PROGRESS TO THE STATUS OF FULL-FLEDGED DEVELOPMENT PROGRAMS, AND (B) ONGOING EFFORTS RELATED TO THE ADVANCEMENT OF COMMERCIAL READINESS AND PROTECTION OF RELATED INTELLECTUAL PROPERTY ACROSS THE DEVELOPMENT LIFECYCLE. THE TEAM COMPRISES THE FULL RANGE OF EXPERTISE AVAILABLE AT AMF, INCLUDING EXECUTIVE MANAGEMENT, RESEARCH SCIENTISTS AND ENGINEERS, LEGAL AND INTELLECTUAL PROPERTY EXPERTS, BUSINESS DEVELOPMENT STRATEGISTS AND ANALYSTS.STATUS RESEARCH AND DEVELOPMENT ACTIVITIES ARE UNDERWAY TO ENHANCE THE CAPABILITIES OF A NEUROMODULATION SYSTEM, COMPRISED OF ADVANCED TECHNOLOGIES AND SYSTEM SOLUTIONS IN SUPPORT OF NEW BUSINESS DEVELOPMENT STRATEGIES.
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IRS990/ProgramServiceRevenueGrp/Desc0NEW PROJECTS
IRS990/ProgramServiceRevenueGrp/Desc1IMPLANTABLE DRUG PUMP (IDP)
IRS990/ProgramServiceRevenueGrp/Desc2IMPLANTABLE MYOELECTRIC SENSOR II
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IRS990/ProgSrvcAccomActy2Grp/Desc0NEW PROJECT DEVELOPMENTTHIS PROGRAM COVERS (A) THE MONITORING AND EVALUATION OF SEVERAL EARLY STAGE ADVANCED RESEARCH AND DEVELOPMENT EFFORTS UNDERWAY THAT ARE DIRECTED AT DEVELOPING - INNOVATIVE TECHNOLOGIES, PROJECT IDEAS AND CONCEPTS BEFORE THEY PROGRESS TO THE STATUS OF FULL-FLEDGED DEVELOPMENT PROGRAMS, AND (B) ONGOING EFFORTS RELATED TO THE ADVANCEMENT OF COMMERCIAL DEVELOPMENT AND PROTECTION OF INTELLECTUAL PROPERTY OF THESE PROJECTS ACROSS THE DEVELOPMENT LIFECYCLE. THE TEAM COMPRISES THE FULL RANGE OF EXPERTISE AVAILABLE AT AMF, INCLUDING - EXECUTIVE MANAGEMENT, RESEARCH SCIENTISTS AND ENGINEERS, LEGAL AND INTELLECTUAL PROPERTY EXPERTS, BUSINESS DEVELOPMENT STRATEGISTS AND ANALYSTS.EXPENSES MAY INCLUDE ONGOING PARTICIPATION IN THE DEVELOPMENT EFFORT INCLUDING RESEARCH AND DEVELOPMENT SUPPORT, COLLABORATION MANAGEMENT, CONFERENCE AND PROFESSIONAL SOCIETY MEETING ATTENDANCE, SERVICE IN MANAGEMENT OR ON THE BOARD OF DIRECTORS OF SPINOUT ENTITIES, PATENT PROSECUTION AND THE PROSECUTION OF INFRINGEMENT ACTIONS TO PROTECT THE VALUE OF THE INTELLECTUAL PROPERTY WE CREATE. IN ADDITION TO PAYROLL EXPENSES AND DIRECT EXPENSES PAID TO OUTSIDE VENDORS FOR GOODS AND SERVICES RELATED TO PROJECTS, EXPENSES IN THIS PROGRAM MAY INCLUDE TRAVEL EXPENSES, PATENT PROSECUTION EXPENSES AND FEES, LEGAL FEES (FOR INTERNAL AND OUTSIDE LEGAL COUNSEL) FOR EXPENSES TO CREATE, PRESERVE AND PROTECT INTELLECTUAL PROPERTY FROM INFRINGEMENT AND REMEDY PAST INFRINGEMENT, AND INCENTIVE AND OTHER COMPENSATION PAYMENTS TO EMPLOYEES AND OTHERS RELATED TO THESE PROGRAMS AND ACTIONS. IN SOME CASES, CERTAIN OF THESE EXPENDITURES MIGHT BE INCURRED LONG AFTER THE PROJECTS HAVE BEEN LAUNCHED INTO SPINOUT COMPANIES OR LICENSED TO THIRD PARTIES.REVENUES ASSOCIATED WITH THESE PROJECTS (SOME OF WHICH MAY ACCRUE LONG AFTER THE PROJECT AND ANY RELATED PROGRAM HAVE BEEN OUT-LICENSED OR LAUNCHED INTO A SPINOUT COMPANY) MAY INCLUDE RECOVERIES OF JUDGMENTS OR SETTLEMENTS FROM PATENT INFRINGEMENT MATTERS, ROYALTIES ON NET SALES OF LICENSED PRODUCTS, MILESTONE PAYMENTS, ONGOING CONTRACT R&D FROM PARTNERS, LICENSEES AND SPINOUT COMPANIES, INTEREST, AND PROCEEDS OF LIQUIDITY EVENTS (E.G., INITIAL PUBLIC OFFERINGS, ACQUISITIONS) INVOLVING RETAINED EQUITY INTERESTS IN PROJECTS THAT HAVE BEEN SPUN OUT AS STARTUP COMPANIES.STATUS:DESIGN AND DEVELOPMENT ACTIVITIES ARE UNDERWAY FOR A NEW BIOELECTRONIC PROGRAM BASED ON THE BUSINESS CASE ANALYSIS CONDUCTED IN THE PRIOR YEAR. THESE ACTIVITIES INCLUDED GENERATION OF INITIAL SYSTEM REQUIREMENTS, ASSEMBLY OF A TEAM OF KEY OPINION LEADERS WITH DOMAIN EXPERTISE, AND THE INITIATION OF SOME FUNDAMENTAL APPLIED RESEARCH IN THE AREA OF NOVEL ELECTRODE DESIGN, INCLUDING COMPLETION OF PRE-CLINICAL TESTING. ADDITIONALLY, THE BUSINESS DEVELOPMENT TEAM, ALONG WITH EXECUTIVE MANAGEMENT AND OTHER STAFF, PERFORMED PRELIMINARY DUE DILIGENCE ON A NUMBER OF ASSETS.
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IRS990/ProgSrvcAccomActy3Grp/Desc0IMPLANTABLE NEUROMODULATION PROJECT #1 TO TREAT CHRONIC DISEASE THE AIM OF THE AMF PROGRAM IS TO DEVELOP A NEUROSTIMULATION SYSTEM THAT WILL IMPROVE MEDICAL OUTCOMES AT A LOWER COST AND/OR HIGHER PATIENT SATISFACTION THAN CURRENTLY AVAILABLE TREATMENT OPTIONS. SUCH A SYSTEM WILL CONSIST OF A FULLY IMPLANTABLE NEURAL STIMULATOR FOR SEAMLESS OPERATION AND REQUIRING MINIMAL INTERACTION FROM A PATIENT, WITH THE GOAL OF OFFERING A HIGHER LEVEL OF PATIENT SATISFACTION, ADOPTION, AND COMPLIANCE.STATUS:FINAL DESIGN VERIFICATION TESTING ACTIVITIES OF THE IMPLANTABLE DEVICE AND EXTERNALS ARE UNDERWAY IN SUPPORT OF A FIRST-IN-HUMAN STUDY. DESIGN AND MANUFACTURING IMPROVEMENTS HAVE BEEN MADE; PRE-CLINICAL ANIMAL STUDIES WERE COMPLETED.
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IRS990/ProgSrvcAccomActyOtherGrp/Desc0IMPLANTABLE NEUROMODULATION PROJECT #2: - TO TREAT A RANGE OF NEUROLOGICAL CONDITIONS. THE SYSTEM WILL CONSIST OF AN IMPLANTABLE NEURAL STIMULATOR AND EXTERNALS DESIGNED TO MAXIMIZE THERAPY OUTCOMES AND PATIENT SATISFACTION WHILE MINIMIZING SYSTEM COSTS.STATUS:PLANNING, DESIGN, AND DEVELOPMENT OF THE FIRST IN-HUMAN IMPLANT AND EXTERNALS IS UNDERWAY; FEASIBILITY PLANNING AND INITIATIVES INCLUDE PRE-CLINICAL STUDIES AND COMPUTATIONAL MODELING OF TARGETED NEURAL STRUCTURES.
IRS990/ProgSrvcAccomActyOtherGrp/Desc1IMPLANTABLE DRUG PUMP (IDP)THE IDP IS A SOPHISTICATED, HIGHLY PROGRAMMABLE DRUG INFUSION DEVICE THAT IS IMPLANTED IN THE BODY AND REFILLED VIA A HYPODERMIC NEEDLE THROUGH THE SKIN. INFUSION RATES AND SCHEDULES MAY BE PROGRAMMED, AND VIA VARIOUS FORMS OF CATHETERS, DRUGS CAN BE DELIVERED INTRATHECALLY TO THE SPINAL COLUMN, INTO THE ABDOMEN, INTO THE BRAIN, OR INTRAVENOUSLY. STATUS: AMF HAS SOLD THE IDP TECHNOLOGY TO A STRATEGIC PARTNER THAT IS AN INTERNATIONAL MEDICAL DEVICE COMPANY. AMF CONTINUES TO SUPPORT THE STRATEGIC PARTNER AS IT WORKS TO ADAPT THE DESIGN FOR DIABETES BY DELIVERING INSULIN TO THE ABDOMEN AND READY IT FOR COMMERCIALIZATION FOR THE BENEFIT OF PATIENTS WITH HARD-TO-TREAT TYPE 1 DIABETES. FIRST-IN-HUMAN IMPLANTATION HAS BEEN ACCOMPLISHED.
IRS990/ProgSrvcAccomActyOtherGrp/Desc2IMPLANTABLE NEUROMODULATION PROJECT #2 - TO TREAT A RANGE OF NEUROLOGICAL CONDITIONS. THE SYSTEM WILL CONSIST OF AN IMPLANTABLE NEURAL STIMULATOR AND EXTERNALS DESIGNED TO MAXIMIZE THERAPY OUTCOMES AND PATIENT SATISFACTION WHILE MINIMIZING SYSTEM COSTS.STATUS PLANNING, DESIGN, AND DEVELOPMENT OF THE FIRST-IN-HUMAN IMPLANT AND EXTERNALS IS UNDERWAY; FEASIBILITY PLANNING AND INITIATIVES INCLUDE PRE-CLINICAL STUDIES AND COMPUTATIONAL MODELING OF TARGETED NEURAL STRUCTURES.
IRS990/ProgSrvcAccomActyOtherGrp/Desc3IMPLANTABLE MYOELECTRIC SENSOR II (IMES INFINITY)THE TECHNOLOGY HAS BEEN LICENSED TO A STRATEGIC PARTNER THAT IS AN INTERNATIONAL MEDICAL DEVICE COMPANY.STATUS:ADDITIONAL ANALYSIS AND DEVELOPMENT WORK WAS DONE TO PREDICT FEASIBILITY OF THE USE OF THE DEVICE ON LOWER LIMBS; DESIGN TRANSFER SUPPORT ACTIVITIES WERE ALSO CONDUCTED.
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