Institute for Systems Biology

“Leroy hood and mark ashida have a business relationship.”

“Form 990 is prepared with assistance from a paid professional advisor based on information prepared by staff. The draft return is reviewed in turn by the director of finance, the coo, and then by the audit committee of the board of directors. The filing version of the return is distributed electronically to all board members prior to filing with the irs.”

“Isb has formal written conflict of interest (coi) policies for all fiduciaries (board members and officers) and research investigators. Both policies require disclosures of any potential conflicts that might exist to be disclosed when conflicts arise and to be summarized annually by completion of a questionnaire. The board of directors delegates investigation and evaluation of potential conflicts to a coi committee (coic). The isb coic is a committee to which the institute delegates the authority to create policies and procedures to address actual and apparent conflicts of interest (fcoi) relating to institute research. If it is determined that a fcoi exists, the isb coic will create and monitor a management plan designed to address the fcoi. The coic is charged with providing appropriate oversight via the isb investigator coi policy, which is intended to ensure that all financial interests are disclosed, that the conduct of funded research is not biased by fcoi, and that the interests of isb are protected. In addition, the coic reviews isb spin-out or start-up companies and advises the isb board's technology transfer committee (ttc) on any potential fcoi issues arising from isb personnel activities and/or interests in the prospective company. The coic is comprised of 8 members: 5 permanent voting, 2 rotating voting, and 1 ex-officio as follows: associate director, compliance (chair of coic) director of sponsored projects (designated institutional official) director of human resources director of finance chief operating officer faculty representative (1 year term) senior research scientist (1 year term) chief compliance officer (ex-officio) the coic meets at least once per quarter to, among other things, review newly identified potential or actual fcoi, discuss the ongoing monitoring of existing fcoi, and assess progress and adherence of management plans. In addition, the coic meets on an ad hoc basis whenever potential fcoi are identified. In the event of a fcoi, the coic will create and monitor a management plan. Management may include but is not limited to: investigator public disclosure of fcoi limitations regarding work/role on a conflicted project divestiture of interests the coic is an independent body which may report, through the chief compliance officer, concerns to the isb board of directors. The policies also require that if a conflict does arise, the covered person will recuse himself or herself from any discussion or vote on the matter.”

“The compensation of the institute's president was reviewed by a paid consultant to determine its comparability to prevailing market conditions for similar positions at other organizations. This study was presented to and approved by the institute's governing board of directors. Also, the employment agreement for the institute's president was reviewed and approved by the institute's governing board of directors. The review process was last performed in july 2011, when the president's compensation was last changed. The compensation of all officers and key employees are based upon and subject to approval of the president and are reviewed and approved by the board of directors as necessary. Typically, this is done when such positions are refilled due to vacancies. This review process was last performed in december 2015.”

“The institute's governing documents, conflict of interest policy, and financial statements are not made readily available to the public. The institute's application for tax exempt status and its annual form 990 are available for public inspection and review upon request.”

“Twelve volunteers served as individual directors on isb's board of directors during 2015. Other volunteers assisted with fundraising mailings and other related tasks.”