Civic Intelligence

The J David Gladstone Institutes

EIN 23-7203666 • 501(c)3 • San Francisco, CA

Profile

To drive a new era of discovery in disease oriented science and to mentor tomorrow's leaders in an inspiring and diverse environment.

Refreshing map…

1650 Owens StreetSan Francisco, CA 94158

www.gladstoneinstitutes.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

70th percentile

0.55x

Higher debt load relative to assets than 70% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2024

Liabilities / Revenue

83rd percentile

1.72x

Higher debt load relative to revenue than 83% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2024

Net Margin

8th percentile

-22%

Higher net margin than 8% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Source year 2024

Top Officer Pay

63rd percentile

$1,182,258

Higher top officer pay than 63% of similar nonprofits.

Top officer pay equals 1.0% of source-year revenue.

501(c)3 • $250M-$1B nonprofits • Source year 2024

Asset Growth

30th percentile

1.8%

Faster asset growth than 30% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Annualized from 2023 to 2024

Revenue Growth

22nd percentile

-0.0%

Faster revenue growth than 22% of similar nonprofits.

501(c)3 • $250M-$1B nonprofits • Annualized from 2023 to 2024

Assets

Up

$371,967,489

Up $13,637,003 (+3.8%) from 2022

Liabilities

Up

$204,371,515

Up $13,684,353 (+7.2%) from 2022

Net Assets

Down

$167,595,974

Down $47,350 (-0.0%) from 2022

Revenue

Down

$119,155,911

Down $25,618,910 (-18%) from 2022

Expenses

Up

$144,808,821

Up $25,852,175 (+22%) from 2022

Net Income

Down

-$25,652,910

Down $51,471,085 (-199%) from 2022

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$400M$300M$200M$100M$0Assets 2010: $338,133,259Liabilities 2010: $164,000,129Net Assets 2010: $174,133,1302010Assets 2012: $311,301,015Liabilities 2012: $155,322,409Net Assets 2012: $155,978,6062012Assets 2013: $292,117,051Liabilities 2013: $137,176,462Net Assets 2013: $154,940,5892013Assets 2014: $287,366,861Liabilities 2014: $132,917,509Net Assets 2014: $154,449,3522014Assets 2016: $259,825,160Liabilities 2016: $140,800,298Net Assets 2016: $119,024,8622016Assets 2017: $270,741,190Liabilities 2017: $138,137,842Net Assets 2017: $132,603,3482017Assets 2018: $257,431,204Liabilities 2018: $126,333,372Net Assets 2018: $131,097,8322018Assets 2019: $314,172,354Liabilities 2019: $189,331,529Net Assets 2019: $124,840,8252019Assets 2020: $318,407,379Liabilities 2020: $197,575,119Net Assets 2020: $120,832,2602020Assets 2021: $367,466,101Liabilities 2021: $191,340,783Net Assets 2021: $176,125,3182021Assets 2022: $358,330,486Liabilities 2022: $190,687,162Net Assets 2022: $167,643,3242022Assets 2024: $371,967,489Liabilities 2024: $204,371,515Net Assets 2024: $167,595,9742024

Highlighted filing

2024

Assets$371,967,489
Liabilities$204,371,515
Net Assets$167,595,974

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$150M$100M$50M$0-$50MExpenses 2010: $78,754,7622010Expenses 2012: $82,921,0172012Revenue 2013: $80,164,886Expenses 2013: $78,842,979Net Income 2013: $1,321,9072013Revenue 2014: $86,317,449Expenses 2014: $81,593,162Net Income 2014: $4,724,2872014Revenue 2016: $67,385,094Expenses 2016: $84,543,592Net Income 2016: -$17,158,4982016Revenue 2017: $84,597,148Expenses 2017: $83,899,382Net Income 2017: $697,7662017Revenue 2018: $86,315,298Expenses 2018: $83,576,420Net Income 2018: $2,738,8782018Revenue 2019: $62,831,350Expenses 2019: $82,269,244Net Income 2019: -$19,437,8942019Revenue 2020: $84,274,665Expenses 2020: $93,512,759Net Income 2020: -$9,238,0942020Revenue 2021: $143,049,979Expenses 2021: $103,017,350Net Income 2021: $40,032,6292021Revenue 2022: $144,774,821Expenses 2022: $118,956,646Net Income 2022: $25,818,1752022Revenue 2024: $119,155,911Expenses 2024: $144,808,821Net Income 2024: -$25,652,9102024

Highlighted filing

2024

Revenue$119,155,911
Expenses$144,808,821
Net Income-$25,652,910

Filings

Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Facts available. Structured filing facts are available, but richer extracted sections are limited.$372$204$168$119$145$25.7
2022Facts available. Structured filing facts are available, but richer extracted sections are limited.$358$191$168$145$119$25.8
2021Facts available. Structured filing facts are available, but richer extracted sections are limited.$367$191$176$143$103$40.0
2020Facts available. Structured filing facts are available, but richer extracted sections are limited.$318$198$121$84.3$93.5$9.24
2019Facts available. Structured filing facts are available, but richer extracted sections are limited.$314$189$125$62.8$82.3$19.4
2018Facts available. Structured filing facts are available, but richer extracted sections are limited.$257$126$131$86.3$83.6$2.74
2017XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$271$138$133$84.6$83.9$0.70
2016XML pending. An XML filing is linked for this year, but detailed extraction is still pending.$260$141$119$67.4$84.5$17.2
2014Detailed filing. Detailed filing data is available for this year.$287$133$154$86.3$81.6$4.72
2013Detailed filing. Detailed filing data is available for this year.$292$137$155$80.2$78.8$1.32
2012Facts available. Structured filing facts are available, but richer extracted sections are limited.$311$155$156$82.9
2010Facts available. Structured filing facts are available, but richer extracted sections are limited.$338$164$174$78.8
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Nov 12, 2025
Return Version
2024v5.2
Gross Receipts
$146,303,822
Mission and Program Overview

Mission

To drive a new era of discovery in disease oriented science and to mentor tomorrow's leaders in an inspiring and diverse environment.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$97,523,142$109,430,919▲ $11,907,777
Investments Other Securities$90,268,077$98,711,481▲ $8,443,404
Land, Buildings, and Equipment, Net$78,563,497$78,446,018▼ $117,479
Pledges and Grants Receivable$30,417,647$24,144,952▼ $6,272,695
Accounts Receivable$6,637,689$8,268,049▲ $1,630,360
Other Notes and Loans Receivable, Net$5,476,998$5,380,000▼ $96,998
Savings and Temporary Cash Investments$22,114,700$4,498,752▼ $17,615,948
Prepaid Expenses and Deferred Charges$2,516,414$2,300,008▼ $216,406
Receivables From Officers Etc$1,925,000$1,850,000▼ $75,000
Cash and Non-Interest-Bearing Accounts$1,781,894$965,066▼ $816,828
Total Assets$365,291,245$371,967,489▲ $6,676,244
Other Assets Total$28,066,187$37,972,244▲ $9,906,057
Liabilities
Mortgage Notes Payable Secured by Investment Property$155,060,000$164,854,940▲ $9,794,940
Other Liabilities$13,328,541$19,200,017▲ $5,871,476
Deferred Revenue$17,176,342$13,971,611▼ $3,204,731
Accounts Payable and Accrued Expenses$7,300,528$6,344,947▼ $955,581
Total Liabilities$192,865,411$204,371,515▲ $11,506,104
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$93,955,280$103,924,580▲ $9,969,300
Net Assets With Donor Restrictions$78,470,554$63,671,394▼ $14,799,160
Total Net Assets Fund Balance$172,425,834$167,595,974▼ $4,829,860
Total Liabilities and Net Assets / Fund Balance$365,291,245$371,967,489▲ $6,676,244

Asset Categories

AssetBook ValueDepreciationBasis
Buildings$30,433,371$26,382,778$56,816,149
Equipment$14,007,350$42,273,225$56,280,575
Leasehold Improvements$17,541,873$37,458,715$55,000,588
Land$13,546,625-$13,546,625
Other Land Buildings$2,916,799-$2,916,799
Other Assets Org$30,000--
Other Securities$98,711,481--

Endowment Activity

PeriodBeginningContrib.Gain/LossOther UsesEnd
2024$5,093,750-▲ $1,165,500$1,181,125$5,078,125
2023$4,127,375-▲ $1,211,500$245,125$5,093,750
2022$5,125,000-▼ $982,000$15,625$4,127,375
2021$5,140,625-▲ $1,344,500$1,360,125$5,125,000
2020$5,156,250--$15,625$5,140,625
Compensation and Service Providers

Employees

NameTitleFull / Part TimeBaseOtherTotal
Deepak SrivastavaPresidentFT$897,915$284,343$1,182,258
Alex MarsonDirectorFT$479,467$266,669$746,136
Robert ObanaCOOFT$524,443$189,393$713,836
Lennart MuckeDirectorFT$615,101$73,040$688,141
Steven M FinkbeinerDirectorFT$561,776$92,115$653,891
Melanie OttDirectorFT$546,722$97,203$643,925
Katherine PollardDirectorFT$528,424$94,881$623,305
Benoit BruneauDirectorFT$523,221$95,961$619,182
Jennifer CrosbyVP of People ServicesFT$377,151$241,089$618,240
Stephen FreedmanVP for Corp Liaison & VenturesFT$482,821$73,040$555,861
Robert WicksVP of PhilanthropyFT$446,501$62,436$508,937
Katerina AkassoglouSr. InvestigatorFT$336,620$146,359$482,979
Michelle SiblyVP of FinanceFT$374,313$82,560$456,873
Andrew S GarbTrustee-$425,000-$425,000
Nicholas J SimonTrustee-$425,000-$425,000
William PriceTrustee-$425,000-$425,000

Highest Paid Contractors

ContractorServicesLocationCompensation
Service By MedallionCustodial Services455 NATIONAL AVENUE, Mountain View, CA 94043$640,917
Schwegman Lundberg WoessnerLegal Services121 SOUTH EIGHTH STREET, Minneapolis, MN 55402$609,129
Moss Adams LLPAccounting ServicesPO BOX 101822, Pasadena, CA 91189$259,626
Goodwin Procter LLPLegal ServicesPO BOX 789882, Philadelphia, PA 19178$216,990
Dg Architects INCArchitectural ServicesPO BOX 511879, Los Angeles, CA 90051$197,129
Revenue and Support

Revenue Composition

Contributions and Grants
$16,072,228
Program Service Revenue
$94,130,588
Investment Income
$8,303,840
Other Revenue
$649,255
All Other Contributions
$8,857,322
Change in Net Assets
$-25,652,910

Noncash Contribution Practices

Property subject to holding requirements
No
Reviewed unusual noncash gifts
Yes
Third parties used for noncash contributions
No

Noncash Contributions

Contribution TypeContribution CountReported AmountValuation Method
Securities Publicly Traded5$2,891,813Fair Market Value (FMV)
Total Noncash Contributions5$2,891,813-
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Salaries, Compensation, and Employee Benefits$75,367,376
Other Expenses$69,441,445
Total Fundraising Expense$2,352,675
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$38,371,002$9,456,414$1,207,785$49,035,201
Fees for Services Other$21,082,185$565,697$414,419$22,062,301
Office Expenses$14,490,600-$41,580$14,532,180
Other Employee Benefits$8,589,033$2,091,215$470,135$11,150,383
Occupancy$6,885,246$679,840$725$7,565,811
Depreciation Depletion$6,758,348$768,835-$7,527,183
Current Officers, Directors, Trustees, and Key Employees$5,598,983$1,375,348$171,343$7,145,674
Interest$6,023,788$959,632-$6,983,420
Pension Plan Contributions$3,621,906$849,374-$4,471,280
Other Expenses$3,760,378--$3,760,378
Payroll Taxes$2,887,657$677,181-$3,564,838
Information Technology$2,051,861-$5,027$2,056,888
Travel$1,285,457$6,314$12,627$1,304,398
Insurance$863,641$271,301-$1,134,942
Fees for Services Legal$635,658$359,668-$995,326
Fees for Service Investment Mgmnt Fees-$476,219-$476,219
All Other Expenses$305,174$37$15,012$320,223
Advertising$253,280$626$14,022$267,928
Fees for Services Accounting-$256,249-$256,249
Royalties$197,999--$197,999
Total Functional Expenses$123,662,196$18,793,950$2,352,675$144,808,821
International Activity

International Summary

Offices
0
Employees
0
Spending
$53,991,325

International Compliance

Activity in boycott countries
No
Foreign corporation ownership
Yes
Foreign partnership interest
Yes
Interest in foreign trust
No
Passive foreign investment company interest
Yes
Transfers to foreign corporations
Yes

International Activities

RegionActivityServicesOfficesEmployeesSpending
Central America and the CaribbeanInvestmentsN/a00$53,991,325
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Receivables from Officers, Directors, Trustees, and Key Employees$1,925,000$1,850,000▼ $75,000
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Operating Lease Liability$5,557,783
Accrued Payroll Liability$4,911,906
457(b) Tiaa-cref Plan Liability$4,389,531
Intercompany Payable$2,446,077
Bond Interest Payable$1,022,265
Employee Benefits Payable$259,000
Flexible Benefits Payable$223,214
Post-doc Pension Plan Payable$131,500
Accrued Royalties Payable$100,000
Other Refund Clearing$66,505
Health Claims Reserve$50,000
Use Tax Payable$29,738
Other Tenant Deposit Payable$12,498
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
Yes
Key decisions subject to board approval
Yes
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 7B

The superior court of california's approval is required for the election and removal of trustees.

Form 990, Part VI, Section B, Line 11B

The form 990 and its related schedules were given to the trustees for review and approval prior to filing.

Form 990, Part VI, Section B, Line 12C

The j. David gladstone institutes requires that each officer, director, trustee and key employee complete a conflict of interest report and report any conflict he/she may have. Any conflicts that arise during the year are required to be reported to the executive director and the trustees immediately. In the event that a conflict does arise that individual is prohibited from participating in the governing body's deliberations and decisions in that transaction.

Form 990, Part VI, Section B, Line 15

The attorney general for the state of california is advised of trustee compensation and the state of california superior court reviews and approves the compensation. An executive compensation report is completed every three (3) years by an independent consulting firm from salary surveys, non-profit form 990's and other sources on organizations that are comparable in size and complexity to the institutes. The last report was completed on 10/16/2024. The president and directors' compensation is approved by the university of california, san francisco vice dean each year. 2024 salaries were approved on 01/08/2024. The institutes' president and trustees utilize similar resources as guidelines when approving compensation for the institutes' key employees, other officers and direct reports. Compensation was last approved on 01/04/2024.

Form 990, Part VI, Section C, Line 19

The organization makes its financial statements, conflict of interest policy and organizational documents available to the public upon request.

Filing and Contact Details

Filer

Filer Name
The J David Gladstone Institutes
EIN
23-7203666
Phone
4157342000
Address
1650 OWENS STREET, SAN FRANCISCO, CA 94158

Signing Officer

Name
Michelle Sibly
Title
Vice President, Finance
Phone
4157342000
Signed
2025-11-12
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Robert Obana
Formed
1972
Legal Domicile
CA
Voting Board Members
3
Independent Board Members
0
Employees
593
Volunteers
90

Preparer

Firm
Baker Tilly Advisory Group Lp
Address
4747 EXECUTIVE DR SUITE 1300, SAN DIEGO, CA 92121
Preparer
Patricia J Mayer
Phone
8586271400
Supplemental Narrative

Additional Explanations

Form 990, Part IX, Line 11G

Service contracts: program service expenses 1,975,746. Management and general expenses 0. Fundraising expenses 0. Total expenses 1,975,746. Subcontracts: program service expenses 10,992,395. Management and general expenses 0. Fundraising expenses 0. Total expenses 10,992,395. Outside laboratory services: program service expenses 3,278,833. Management and general expenses 0. Fundraising expenses 0. Total expenses 3,278,833. Other services: program service expenses 4,835,211. Management and general expenses 565,697. Fundraising expenses 414,419. Total expenses 5,815,327.

FORM 990, PART XI, LINE 9:

K-1 PASSTHROUGH -135.

Financial Statement Notes

PART V, LINE 4:

The donor restricted endowment funds have been restricted to fund specific scientific research projects. Research will be performed on these projects over the next few years. Permanently restricted fund earnings will be spent on scientific research and administration.

PART X, LINE 2:

The institutes has been granted exemption from income taxes under section 501(c)(3) of the internal revenue code and section 23701d of the california revenue and taxation code. The institutes is subject to unrelated business income tax on certain rental transactions and income from alternative investments. For the years ended december 31, 2024 and 2023, the institutes had approximately $12,061,000 and $12,002,000 of cumulative taxable losses, respectively. Since management believes it is unlikely there will be future income to offset these losses, a valuation allowance has been reflected against the full balance. The institutes files an exempt organization return and applicable unrelated business income tax returns in the u.s. Federal jurisdiction and with the franchise tax board in the state of california. The institutes had no unrecognized tax benefits at december 31, 2024 and 2023.

Raw XML AppendixShowing 400 of 1,162 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0THE INSTITUTE OF NEUROLOGICAL DISEASE MAINTAINS A STRONG FOCUS ON NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES, INCLUDING ALZHEIMER'S DISEASE AND OTHER DEMENTIAS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS (ALS), AND MULTIPLE SCLEROSIS. THE INVESTIGATORS ARE SEARCHING FOR COMMON THREADS THAT WILL ALLOW THEM TO IDENTIFY THERAPEUTIC INTERVENTIONS THAT MIGHT BENEFIT MULTIPLE CONDITIONS. THEY ARE USING UNCONVENTIONAL APPROACHES TO IDENTIFY SUCH MULTI-FACETED SOLUTIONS, WHILE ALSO LEVERAGING CAPABILITIES IN REGENERATIVE AND PERSONALIZED MEDICINE.
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IRS990/MissionDesc0TO DRIVE A NEW ERA OF DISCOVERY IN DISEASE ORIENTED SCIENCE AND TO MENTOR TOMORROW'S LEADERS IN AN INSPIRING AND DIVERSE ENVIRONMENT.
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