Musculoskeletal Transplant Foundation Inc.

“Mtf is organized with two classes of membership which are (1) non- corporate membership and (2) corporate membership. The non-corporate members include academic members, recovery members and research members. The sole corporate member of mtf is biocon, inc.”

“The sole corporate member may appoint all directors subject to the following: the current chairperson and vice chair of mtf's "medical board of trustees" will be appointed to the board. Also, the current chairperson and vice chair of mtf's "donation board of trustees" will be appointed members of the board of directors.”

“Any changes that are a material change to the governing documents of the foundation (ex.by-laws or articles of incorporation) must be approved by the members of the foundation's medical board of trustees and the donation board of trustees. Final approval of these changes must be approved by the board of directors.”

“Members of the audit committee of the board of directors were provided with a paper copy of form 990. The 990 was reviewed at an open meeting of the audit committee. Subsequent to modifications, if any, as a result of the audit committee meeting, the form 990 is then circulated to all members of the board of directors for their final review and approval before filing.”

“Mtf sends a comprehensive questionnaire annually to board members, officers and key employees requesting disclosure of any conflicts of interest.”

“Executive compensation review: each year, mtf reviews and assesses the reasonableness of total compensation arrangements for our executive team, including the ceo. The analysis incorporates compensation survey data, form 990's of companies of related industries and similar size. A blend of both for-profit and not-for-profit companies is used. Every third year, mtf retains the services of an independent compensation consultant to ascertain and determine that mtf is paying and providing a reasonable total compensation package to their executives and to provide an opinion letter of their findings. Compensation committee review mtf's board of directors established a compensation committee in 1995. The responsibility of the committee was to initially review and recommend to the board approval of executive and staff compensation and changes to benefits. In 2000, the authority of the committee was expanded to include the approval of such compensation and benefits and reporting such approvals to the board. The compensation committee typically meets semi-annually to review merit and bonus recommendations. A copy of the compensation committee's charter, agendas, meeting materials, and meeting minutes are maintained.”

“Yes. The process is the same as described above in line 15a.”

“Upon request, mtf will provide public documents through email, mailings, or office visits.”

“Musculoskeletal transplant foundation, inc. ("mtf- or the "foundation") is dedicated to providing quality allograft tissue for transplantation through a commitment to excellence in education, research, recovery, and care for recipients, donors and their families. Mtf continues to promote the health and welfare of the general public by (1)maximizing the availability of high quality human tissue including bone and dermal tissue; 2)supporting medical, scientific and other educational research with respect to tissue donation, recovery and transplantation; (3)educating the general public with respect to the importance and benefits of tissue donation and transplantation; and (4)otherwise promoting tissue donation through a commitment to excellence in education, research, recovery and care for donors, recipients, and their families. The musculoskeletal transplant foundation, inc. Was incorporated on january 30, 1987, as a district of columbia non-profit membership organization and is a 501(c)(3) organization. There is a critical need for musculoskeletal, cardiovascular, skin and ocular tissue for transplantation. In order to accomplish mtf's mission and these activities, the foundation maintains a donor recovery network, supports donor awareness programs for the public, donates bone and other tissue for research, provides research grants, and otherwise supports bone, skin, woundcare and cardiovascular tissue transplantation, research and educational programs. The foundation's membership is comprised of 501(c)(3) non-proit organizations. The membership consists of fifty academic members (orthopaedic teaching institutions), twenty-five recovery organizations (organ, eye and tissue procurement organizations)throughout the united states. Biocon,inc., a non-profit 501(c)(3) organization, serves as the sole corporate member of the foundation. The foundation maintains a nationwide donor recovery network that is based on its affiliation with its recovery and referring members. This national network allows the public to quickly access needed allograft tissue. Bone and other allograft tissue recovered through this network is subject to standardized screening criteria for donation established by the foundation's medical board of trustees and donation board of trustees (described below). The foundation also maintains a quality assurance program with respect to allograft tissues recovered through the network. This quality program is based on the policies adopted by the american association of tissue banks and the regulations published by the food & drug administration and other regulatory agencies outside the u.s where the oundation distributes tissue. The foundation provides recovery organization members and the general community they serve with funding for hospital development and donor awareness services. These services also include providing training to recovery organization members, educational symposiums to both recovery organization members and hospital staff, and educational materials for use in seminars to hospital professionals and the general public. As indicated in article iii of the foundation's bylaws, a member of the foundation can be an academic medical institution with an accredited residency trainng program; a federally chartered opo; or an eye/tissue bank. All members agree to support the foundation's mission either through a services and supply agreement or services and recovery agreement. Some members are eligible for research funding (see sched. I, pt. Iv for grant program overview) from the foundation upon recommendation and/or approval of either the board of directors or the medical board of trustees. Although all of the foundation's members are non-profit 501(c)(3) organizations, the foundation makes its transplantation tissue network and programs available to any person or organization (typically through their hospitals and physicians) in need of allograft tissue. The foundation funds all costs associated with the recove”

“Donor family services volunteer roles - clerical: packet development, photocopying, assisting with mailings, organizing materials, filing, preparation and mailing of sympathy, birthday and anniversary, and thinking of you cards, packaging, preparation and mailing of shawls,etc. Data entry: survey data entry special projects: review of materials, program development, research,public relations, web design and information,newsletter design and information, etc. Speaker's bureau: participation with mtf staff to educate the public and professionals, media interviews, health fairs, etc. Donor family council: participation on council with other donor families through telephone calls, email, and other written communication for the following: donor family program development and implementation, including: follow-up bereavement program for families, review process, review letter and brochures, review surveys, review bereavement materials, ethical issues”

“Orthopadedic and general surgical applications. Mtf continues to seek new applications for the use of the gift of allograft tissues to resolve unmet clinical needs and continues to provide special tissue for research performed by members of the armed forces institute of regenerative medicine which is an organization dedicated to developing medical therapies and treatments for wounded soldiers. In 2017, mtf experienced continued progress in orthopaedics markets including sports medicine and spine and continued expansion of tissue forms in plastic and reconstructive surgery and wound care. Highlights include; the introduction of new technology that extends the useful life of fresh osteochondral grafts, thereby, providing more time to match donor tissue to a recipient; new precision and demineralized bone fiber based tissue platforms for inner body spine applications. In plastic and reconstructive surgery, mtf expanded use of renuva, an allograft adipose matrix to treat small volume defects; profile pre-shaped cartilage segments for rhineoplasty procedures, mitigating the need to harvest a rib segment from the patient; mtf's flex hd dermal tissue line was expanded to include larger sizes of flex hd pliable to accommodate the emerging pre- pec technique, offering ease of use for plastic surgeons and improved aesthetic outcomes for breast reconstruction patients post mastectomy. In wound care (allograft based biologic), mtf continued the development of existing offerings while expanding the line to include viable amnioband sheets for the treatment of diabetic and venous ulcers. Mtf's continued support (since 2013) of the american society of plastic surgeons (asps) and the plastic surgery foundation (psf)includes participation in breast recontruction awareness day in october each year. As a sponsor, mtf, joined the world's largest organization of board certified plastic surgeons in a campaign to support breast cancer survivors' rights to make an informed decision when choosing breast reconstruction options. Mtf also extended its support of biologic research through the plastic surgery foundation (psf), with a financial pledge of 1m over five years. In 2017 mtf enhanced its compendium of clincal studies providing for expanded reimbursement coverage for tissue therapies in wound care and breast reconstruction throughout the united states. Mtf also initiated the first ever prospective randomized clinical trial for acellular dermal matrix used for breast reconstruction following mastectomy. In 2016 mtf made significant progress in orthopaedics including sports medicine and spine; successful expansion of tissue forms in plastic and reconstructive surgery and wound care. A new tissue platform was introduced for spine applications with plans to make these tissue forms available in chronic wound care applications. The properties of this tissue provide new options for treatment of surgical and chronic wounds. In plastic and reconstructive surgery, mtf introduced a dehydrated allograft adipose matrix that can be stored at room temperature and hydrated for injection at the time of use. Mtf's dermal tissue line was expanded to include flex hd max to enhance aesthetic outcomes after breast reconstruction surgery. In 2016 mtf improved the time to healing of wound care tissue forms and expanded the reimbursement coverage for the wound care division throughout the united states. In 2016 the foundation continued with its efforts to expand entry into the wound care market with advanced wound care tissues. Amnioband, dehydrated amnion/chorion membrane based on placental tissue recovery was launched in 2015 for the treatment of diabetic and venous ulcers. Reimbursement was also secured for amnioband and coverage was approved by several medicare administrative contractors during the year. In the orthopedic sports tissue market, mtf launched cam, dehydrated cartilage particles for repair of focal cartilage defects. For individual stories of donor familie”

“Mtf is not required to file form 990-t because mtf's gross income from unrelated business activities is less than 1,000. Mtf may file a form 990-t to establish net operating loss and other carry-forwards to future years.”

“CANADA”

“Net loss on investment in bone biologics, inc. -2,890,280 accrued grants/grants paid 337,284 book /tax depreciation difference 1,083,333 total -1,469,663”