Musculoskeletal Transplant

“Mtf is organized with two classes of membership which are (1) non- corporate membership and (2) corporate membership. The non-corporate members include academic members, recovery members and research members. The sole corporate member of mtf is biocon, inc.”

“The sole corporate member may appoint all directors subject to the following: the current chairperson and vice chair of mtf's "medical board of trustees" will be appointed to the board. Also, the current chairperson and vice chair of mtf's "donation board of trustees" will be appointed members of the board of directors.”

“Any changes that are a material change to the governing documents of the foundation (ex.by-laws or articles of incorporation) must be approved by the members of the foundation's medical board of trustees and the donation board of trustees. Final approval of these changes must be approved by the board of directors.”

“Members of the audit committee of the board of directors were provided with a copy of form 990. The 990 was reviewed at an open meeting of the audit committee. Subsequent to modifications, if any, as a result of the audit committee meeting, the form 990 is then circulated to all members of the board of directors for their final review and approval before filing.”

“Mtf sends a comprehensive questionnaire annually to board members, officers and key employees requesting disclosure of any conflicts of interest. Mtf is diligent in reviewing the annual disclosure forms submitted by the covered persons, and in screening, compiling and maintaining the submissions.”

“Executive compensation review: each year, mtf reviews and assesses the reasonableness of total compensation arrangements for our executive team, including the ceo. The analysis incorporates compensation survey data, last compiled in july 2023, form 990's of companies of related industries and similar size. A blend of both for-profit and not-for-profit companies is used. Every third year (most recently july 2023), mtf retains the services of an independent compensation consultant to ascertain and determine that mtf is paying and providing a reasonable total compensation package to their executives and to provide an opinion letter of their findings. Compensation committee review: mtf's board of directors established a compensation committee in 1995. The responsibility of the committee includes the review and approval of executive and staff compensation and benefits. The compensation committee typically meets semi-annually to review merit and bonus recommendations. A copy of the compensation committee's charter, agendas, meeting materials, and meeting minutes are maintained.”

“The process is the same as described above in line 15a.”

“Mtf makes its form 990 and other public documents available to the public at its regular place of business in person, requests through email or via us postal service. In addition form 990 is available on the internet at www.guidestar.org.”

“Musculoskeletal transplant foundation, inc. ("mtf- or the "foundation") is dedicated to providing quality allograft tissue for transplantation through a commitment to excellence in education, research, recovery, and care for recipients, donors and their families. Mtf continues to promote the health and welfare of the general public by (1) maximizing the availability of high quality human tissue including bone, dermal and birth tissue; 2) supporting medical, scientific and other educational research with respect to tissue donation, recovery and transplantation; and(3) educating the general public with respect to the importance and benefits of tissue donation and transplantation. The musculoskeletal transplant foundation, inc. Was incorporated on january 30, 1987, as a district of columbia non- profit membership organization and is a 501(c)(3)organization. There is a critical need for musculoskeletal, cardiovascular, skin, birth and ocular tissue for transplantation. In order to accomplish mtf's mission and these activities, the foundation maintains a donor recovery network, supports donor awareness programs for the public, donates bone and other tissue for research, provides research grants, and otherwise supports bone, skin, wound care and cardiovascular tissue transplantation, research and educational programs. The foundation's membership is comprised of 501(c)(3) non-profit organizations. The membership consists of forty-six academic members (orthopedic teaching institutions), thirty-one recovery organizations (organ, eye and tissue procurement organizations) throughout the united states. Biocon, inc., a non-profit 501(c)(3) organization, serves as the sole corporate member of the foundation. The foundation maintains a nationwide donor recovery network that is based on its affiliation with its recovery and referring members. This national network allows the public to quickly access needed allograft tissue. Bone and other allograft tissue recovered through this network is subject to standardized screening criteria for donation established by the foundation's medical board of trustees and donation board of trustees (described below). The foundation also maintains a quality assurance program with respect to allograft tissues recovered through the network. This quality program is based on the policies adopted by the american association of tissue banks and the regulations published by the food & drug administration and other regulatory agencies outside the u.s where the foundation distributes tissue. The foundation provides recovery organization members and the general community they serve with funding for hospital development and donor awareness services. These services also include providing training to recovery organization members, educational symposiums to both recovery organization members and hospital staff, and educational materials for use in seminars to hospital professionals and the general public. As indicated in article iii of the foundation's bylaws, a member of the foundation can be an academic medical institution with an accredited residency training program; a federally chartered opo; or an eye/tissue bank. All members agree to support the foundation's mission either through a services and supply agreement or services and recovery agreement. Some members are eligible for research funding (see schedule i, pt. Iv for grant program overview) from the foundation upon recommendation and/or approval of either the board of directors or the medical board of trustees. Although all of the foundation's members are non-profit 501(c)(3) organizations, the foundation makes its transplantation tissue network and programs available to any person or organization (typically through their hospitals and physicians)in need of allograft tissue. The foundation funds all costs associated with the recovery of donor tissues. It supports these costs with fees intended to cover its expenses (including funding for research) from the user of”

“Compassionate care for donor families is at the heart of our mission at mtf the donor family support services volunteers never forgets the magnitude of the gift our donors and their families make. We've set this site up just for you, a place you can come to learn about tissue donation, find helpful resources and more. Www.mtfbiologics.org/who-we-serve/donors-community/donors-families our volunteers are there to help you cope with your loss, while appreciating the incredible gift your loved one has made to others including periodic personal phone calls, remembrances including sympathy cards, free informative packet with bereavement support literature, support group information and more. Mtf volunteer groups comprised of donor family members and birth tissue donors who share their stories and encourage others to consider donation. Many families have found that being involved with other donor families has a profound effect on their lives and appreciate the opportunity to share the story of their loved ones. Tissue recipients have inspirational stories of how a transplant transformed their lives. Our volunteers are located throughout the country. We can provide you with information on how you can get involved and volunteer by contacting [email protected]. The linking lives program is a voluntary program that gives tissue recipients the opportunity to write a letter of thanks to their donor family. Recipients are encouraged to write a letter which mtf will forward to the agency that coordinated the tissue recovery. We provide tissue recipients with guidelines for writing to their donor family. The recovery agency sends the letter to the donor family. Donor families may not hear from their tissue recipients as many patients are unaware that they can write to their donor families. However, those who do receive a letter from a grateful tissue recipient have shared how important those letters can be.”

“Mtf is a global nonprofit organization that saves and heals lives by honoring donated gifts and serving patients, we collaborate with the medical, scientific, as well as organ and tissue donation communities. Our goal is simple-do what's right for patients, surgeons, tissue donors, and their families through our guiding principles: - we transform by providing safe, high-quality grafts from donated human tissues that are used in a growing array of clinical fields. - we collaborate by forging relationships with experts in tissue and organ recovery, as well as leading physicians and scientists, to accelerate innovation and ensure the best possible experiences and outcomes for patients. - we innovate by advancing the science of transplantation by supporting research within our own organization and among clinicians and researchers worldwide. - we give back by reinvesting in research to positively affect lives across the globe. Since its inception in 1987, mtf, the nation's leading tissue bank, has received tissue donations from over 160,000 donors. In 2022, mtf recovered tissue from over 6,000 donors for use in musculoskeletal and bone allograft applications, over 5,200 donors for use in burn, general, and plastic surgery applications, over 1,000 birth tissue donors for use predominantly in wound care applications and over 900 donors for organs and tissues for research. Overall, mtf distributed approximately 465,000 units of allograft tissue during 2022. Mtf is focused on saving and healing lives and continues to develop and innovate human tissue solutions to solve clinical problems. Mtf has also continued its efforts to provide research tissue and grant funding for research and development performed by academic centers and entrepreneurs alike. In 2022 mtf continued to pursue its mission, and made tissue forms available in the orthopedic, plastic and reconstructive surgery, and wound care markets through both internal and external distribution relationships. Mtf orthopedics launched multiple new tissue forms in 2022 that positioned the foundation and our partners to help many more patients in the years to come. Mtf also initiated process efficiencies that will maximize the gift of donation and will provide more opportunities to surgeons to elevate the continuum of care. In the plastic and reconstructive surgery franchise, mtf continued to take advantage of opportunities in buying group contracts. Continued focus was placed on processing efficiencies and donor recovery methods to maximize the gift of donation. Mtf continued to bolster its inter-industry partnerships, increasing the availability of donated human tissue, and the ability to bring human tissue allografts to surgeons and patients. Mtf's wound care continued growing throughout 2022, expanding its presence in the space via representation and processing capability. Mtf generated more clinical and health care economic data to further the expansion in wound care and plastic and reconstructive surgery procedures, further illustrating the safety and value of its tissue forms. Mtf's mission is to save and heal lives by honoring the donated gift, serving patients and advancing science. For individual stories about donor families, please visit mtf biologics website at https://www.mtfbiologics.org/who-we-serve/donors- community/donors-families. Stories about recipients are also available on the website at https://www.mtfbiologics.org/who-we-serve/donors- community/recipients.”

“CANADA”

“Unrealized foreign exchange 65,000 unrealized foreign exchange -538,473 grants paid 75,423 total -398,050”