Civic Intelligence

International AIDS Vaccine

EIN 13-3870223 • 501(c)3 • New York, NY

Profile

A nonprofit scientific research organization that develops vaccines and antibodies for hiv, tuberculosis, emerging infectious diseases, and neglected diseases.

125 Broad Street 9th FLNew York, NY 10004

www.iavi.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

74th percentile

0.60x

Higher debt load relative to assets than 74% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Liabilities / Revenue

61st percentile

0.60x

Higher debt load relative to revenue than 61% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Net Margin

15th percentile

-9.0%

Higher net margin than 15% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Top Officer Pay

72nd percentile

$784,374

Higher top officer pay than 72% of similar nonprofits.

Top officer pay equals 0.6% of source-year revenue.

501(c)3 • $100M-$250M nonprofits • Source year 2024

Asset Growth

44th percentile

4.5%

Faster asset growth than 44% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2023 to 2024

Revenue Growth

30th percentile

1.2%

Faster revenue growth than 30% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2023 to 2024

Assets

Up

$129,852,638

Up $5,618,695 (+4.5%) from 2023

Liabilities

Up

$78,459,588

Up $18,149,397 (+30%) from 2023

Net Assets

Down

$51,393,050

Down $12,530,702 (-20%) from 2023

Revenue

Up

$131,181,475

Up $1,503,075 (+1.2%) from 2023

Expenses

Up

$143,043,595

Up $10,147,358 (+7.6%) from 2023

Net Income

Down

-$11,862,120

Down $8,644,283 (-269%) from 2023

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$150M$100M$50M$0Assets 2010: $116,319,236Liabilities 2010: $21,524,437Net Assets 2010: $94,794,7992010Assets 2011: $99,007,459Liabilities 2011: $22,673,858Net Assets 2011: $76,333,6012011Assets 2012: $90,186,843Liabilities 2012: $21,657,630Net Assets 2012: $68,529,2132012Assets 2013: $105,112,068Liabilities 2013: $29,307,883Net Assets 2013: $75,804,1852013Assets 2014: $92,681,919Liabilities 2014: $39,972,128Net Assets 2014: $52,709,7912014Assets 2015: $85,094,617Liabilities 2015: $28,190,268Net Assets 2015: $56,904,3492015Assets 2016: $89,152,233Liabilities 2016: $42,089,479Net Assets 2016: $47,062,7542016Assets 2017: $81,959,513Liabilities 2017: $38,044,228Net Assets 2017: $43,915,2852017Assets 2018: $83,382,669Liabilities 2018: $46,200,945Net Assets 2018: $37,181,7242018Assets 2019: $74,755,062Liabilities 2019: $37,098,538Net Assets 2019: $37,656,5242019Assets 2020: $81,721,759Liabilities 2020: $42,470,719Net Assets 2020: $39,251,0402020Assets 2021: $107,049,023Liabilities 2021: $56,078,728Net Assets 2021: $50,970,2952021Assets 2022: $128,948,484Liabilities 2022: $62,681,430Net Assets 2022: $66,267,0542022Assets 2023: $124,233,943Liabilities 2023: $60,310,191Net Assets 2023: $63,923,7522023Assets 2024: $129,852,638Liabilities 2024: $78,459,588Net Assets 2024: $51,393,0502024

Highlighted filing

2024

Assets$129,852,638
Liabilities$78,459,588
Net Assets$51,393,050

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$150M$100M$50M$0-$50MExpenses 2010: $81,998,2952010Revenue 2011: $60,597,835Expenses 2011: $79,059,033Net Income 2011: -$18,461,1982011Expenses 2012: $69,073,4112012Revenue 2013: $66,366,876Expenses 2013: $58,739,167Net Income 2013: $7,627,7092013Revenue 2014: $52,466,584Expenses 2014: $59,988,992Net Income 2014: -$7,522,4082014Revenue 2015: $72,394,949Expenses 2015: $67,690,431Net Income 2015: $4,704,5182015Revenue 2016: $65,023,177Expenses 2016: $73,947,939Net Income 2016: -$8,924,7622016Revenue 2017: $80,526,964Expenses 2017: $85,397,465Net Income 2017: -$4,870,5012017Revenue 2018: $77,192,773Expenses 2018: $83,383,050Net Income 2018: -$6,190,2772018Revenue 2019: $88,458,944Expenses 2019: $87,783,507Net Income 2019: $675,4372019Revenue 2020: $97,111,665Expenses 2020: $96,068,184Net Income 2020: $1,043,4812020Revenue 2021: $126,352,598Expenses 2021: $113,151,683Net Income 2021: $13,200,9152021Revenue 2022: $146,782,280Expenses 2022: $131,188,762Net Income 2022: $15,593,5182022Revenue 2023: $129,678,400Expenses 2023: $132,896,237Net Income 2023: -$3,217,8372023Revenue 2024: $131,181,475Expenses 2024: $143,043,595Net Income 2024: -$11,862,1202024

Highlighted filing

2024

Revenue$131,181,475
Expenses$143,043,595
Net Income-$11,862,120

Filings

Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Facts available. Structured filing facts are available, but richer extracted sections are limited.$130$78.5$51.4$131$143$11.9
2023Detailed filing. Detailed filing data is available for this year.$124$60.3$63.9$130$133$3.22
2022Detailed filing. Detailed filing data is available for this year.$129$62.7$66.3$147$131$15.6
2021Detailed filing. Detailed filing data is available for this year.$107$56.1$51.0$126$113$13.2
2020Detailed filing. Detailed filing data is available for this year.$81.7$42.5$39.3$97.1$96.1$1.04
2019Detailed filing. Detailed filing data is available for this year.$74.8$37.1$37.7$88.5$87.8$0.68
2018Detailed filing. Detailed filing data is available for this year.$83.4$46.2$37.2$77.2$83.4$6.19
2017Detailed filing. Detailed filing data is available for this year.$82.0$38.0$43.9$80.5$85.4$4.87
2016Detailed filing. Detailed filing data is available for this year.$89.2$42.1$47.1$65.0$73.9$8.92
2015Detailed filing. Detailed filing data is available for this year.$85.1$28.2$56.9$72.4$67.7$4.70
2014Detailed filing. Detailed filing data is available for this year.$92.7$40.0$52.7$52.5$60.0$7.52
2013Detailed filing. Detailed filing data is available for this year.$105$29.3$75.8$66.4$58.7$7.63
2012Facts available. Structured filing facts are available, but richer extracted sections are limited.$90.2$21.7$68.5$69.1
2011Summary only. Only limited summary data is available for this year.$99.0$22.7$76.3$60.6$79.1$18.5
2010Facts available. Structured filing facts are available, but richer extracted sections are limited.$116$21.5$94.8$82.0
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Oct 30, 2025
Return Version
2024v5.2
Gross Receipts
$139,202,371
Mission and Program Overview

Mission

International aids vaccine initiative (iavi) is a global initiative dedicated to ensure the development of safe, effective, accessible, preventive hiv vaccines for use throughout the world.

Translate scientific discoveries into affordable, globally accessible public health solutions

Balance Sheet Detail
LineBeginningEndChange
Assets
Pledges and Grants Receivable$46,434,558$43,074,450▼ $3,360,108
Investments in Publicly Traded Securities$33,407,409$36,526,217▲ $3,118,808
Savings and Temporary Cash Investments$34,403,229$18,632,887▼ $15,770,342
Land, Buildings, and Equipment, Net$927,381$841,193▼ $86,188
Prepaid Expenses and Deferred Charges$146,763$241,274▲ $94,511
Accounts Receivable$279,535$219,130▼ $60,405
Total Assets$124,233,943$129,852,638▲ $5,618,695
Other Assets Total$8,635,068$30,317,487▲ $21,682,419
Liabilities
Deferred Revenue$28,968,880$31,126,467▲ $2,157,587
Other Liabilities$10,139,300$30,129,065▲ $19,989,765
Grants Payable$11,781,746$9,292,944▼ $2,488,802
Accounts Payable and Accrued Expenses$9,420,265$7,911,112▼ $1,509,153
Total Liabilities$60,310,191$78,459,588▲ $18,149,397
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$32,056,013$27,604,225▼ $4,451,788
Net Assets With Donor Restrictions$31,867,739$23,788,825▼ $8,078,914
Total Net Assets Fund Balance$63,923,752$51,393,050▼ $12,530,702
Total Liabilities and Net Assets / Fund Balance$124,233,943$129,852,638▲ $5,618,695

Asset Categories

AssetBook ValueDepreciationBasis
Equipment$539,348$27,259,816$27,799,164
Leasehold Improvements$301,845$20,003,216$20,305,061
Other Assets Org$29,791,571--
Compensation and Service Providers

Employees

NameTitleFull / Part TimeBaseOtherTotal
Mark B FeinbergPresident/CEOFT$594,776$189,598$784,374
Ana Cespedes MontoyaChief Operating OfficerFT$456,945$157,189$614,134
Swati GuptaVP, Head of Eid and EpidemiologyFT$336,711$134,025$470,736
Christopher ParksAss. VP, Viral Vacc. & Head of DdlFT$315,208$136,879$452,087
Mario GaglianoChief People Officer, VP of HrFT$336,672$108,513$445,185
Dagna LauferVP and Head of Clinical DevelopmentFT$339,864$101,922$441,786
Min DingGeneral Counsel/board SecretaryFT$306,375$134,643$441,018
Louis D SchwartzAsst. Sec., Chief Fin. & Admin Off.FT$293,701$128,405$422,106
Marion GruberVP, Public Health & Reg. ScienceFT$330,252$91,825$422,077
Sangeetha SagarVice President, PdcFT$352,921$66,922$419,843
Brandon SaftDeputy Chief Financial OfficerFT$217,613$60,465$278,078

Board Members and Trustees

NameTitle
Eric Paul GoosbyBoard Chair
Alexis M PintoBoard Member
Anne Martin SimondsBoard Member
David BlumbergBoard Member
Jim ConnollyBoard Member
John W ShiverBoard Member
Linda-gail BeckerBoard Member
Marijke WijnroksBoard Member
Mark DybulBoard Member
Rajeev VenkayyaBoard Member
Susan SilbermannBoard Member
Wafaa El-sadrBoard Member
Robert GoldbergBoard Treasurer

Highest Paid Contractors

ContractorServicesLocationCompensation
Emmes CorporationClinical Research Studies401 N WASHINGTON ST STE 700, Rockville, MD 20850, Ca$1,294,397
Itr Laboratories Canada INCReg. Affairs/pre-clinical Cons.1425 PLAIN CITY-GEORGESVILLE RD, West Jefferson, OH 43162, Sf$752,190
WhcProgram ConsultantPO BOX 253, Vermont, VICTORIA, As$551,389
AmplifybioReg. Affairs/pre-clinical Cons.-$426,100
Australian Biologics Pty LtdLegal Services-$376,692
Revenue and Support

Revenue Composition

Contributions and Grants
$126,009,254
Program Service Revenue
$2,511,798
Investment Income
$2,295,284
Other Revenue
$365,139
All Other Contributions
$60,250,518
Change in Net Assets
$-11,862,120

Audited Revenue Reconciliation

Revenue per Audited Statements
$130,907,412
Revenue Not Reported on Financial Statements
$274,063
Revenue Not Reported on Form 990
$1,547,560
Other Revenue Adjustments
$198,635
Total Revenue per Audited Statements
$132,454,972
Total Revenue per Form 990
$131,181,475
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$58,512,176
Salaries, Compensation, and Employee Benefits$50,838,786
Grants and Similar Amounts Paid$33,692,633
Total Fundraising Expense$223,595
Professional Fundraising Fees$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$28,906,033$8,788,918$19,325$37,714,276
Foreign Grants$25,741,228--$25,741,228
Grants to Domestic Orgs$7,951,405--$7,951,405
Occupancy$4,017,180$436,835-$4,454,015
Other Employee Benefits$3,877,629$64,440-$3,942,069
Pension Plan Contributions$3,378,540--$3,378,540
Current Officers, Directors, Trustees, and Key Employees$182,329$2,802,568-$2,984,897
Payroll Taxes$2,819,004--$2,819,004
Travel$1,853,259$329,461$4,445$2,187,165
Information Technology$1,625,717$485,041-$2,110,758
Office Expenses$737,670$366,968-$1,104,638
Fees for Services Other$106,489$961,755-$1,068,244
Depreciation Depletion$535,859$45,904-$581,763
Fees for Services Legal$146,199$399,742-$545,941
Insurance$329,698$135,639-$465,337
Other Expenses$288,378$22,757-$288,378
All Other Expenses$112,487$131,618$19,825$263,930
Fees for Services Accounting-$201,935-$201,935
Fees for Services Lobbying--$180,000$180,000
Fees for Service Investment Mgmnt Fees-$75,428-$75,428
Total Functional Expenses$127,097,658$15,722,342$223,595$143,043,595

Audited Expense Reconciliation

Line ItemAmount
Total Expenses per Audited Statements$143,484,259
Total Expenses per Form 990$143,043,595
Expenses per Audited Statements$131,208,183
Expenses Not Reported on Form 990$12,276,076
Expenses Not Reported on Financial Statements$11,835,412
Other Expense Adjustments$11,759,984
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
The Scripps Research Institute - OspLa Jolla, CA501(c)(3)Research & Development$2,739,912
Fhi Clinical IncDurham, NC-Research & Development$1,375,993
Boston UniversityBoston, MA501(c)(3)Research & Development$936,607
Resilience Government Services IncAlachua, FL501(c)(3)Research & Development$520,971
Emory UniversityAtlanta, GA501(c)(3)Research & Development$352,302
SEATTLE CHILDREN'S HOSPITALSeattle, WA501(c)(3)Research & Development$309,599
La Jolla Institute for Allergy & ImmunologyLa Jolla, CA501(c)(3)Research & Development$277,125
Massachusetts General HospitalBoston, MA-Research & Development$232,251
Northwestern UniversityChicago, IL501(c)(3)Research & Development$200,000
The Mitchell Group Inc (tmg)Washington, DC501(c)(3)Research & Development$168,266
University of North Caroline Chapel HillChapel Hill, NC501(c)(3)Research & Development$138,380
Resilience US IncLa Jolla, CA-Research & Development$127,099
THE BRIGHAM AND WOMEN'S HOPITAL INCBoston, MA501(c)(3)Research & Development$115,765
Applied Biomedical Science InstituteSan Diego, CA501(c)(3)Research & Development$86,085
Genscript USA IncorporatedPiscataway, NJ-Research & Development$77,610
Texas Biomedical Research InstituteSan Antonio, TX501(c)(3)Research & Development$61,388
Johns Hopkins UniversityBaltimore, MD-Research & Development$51,745
Lsb Research Group LLCMiles, TX501(c)(3)Research & Development$47,500
Suny Graduate SchoolAlbany, NY501(c)(3)Research & Development$39,028
The Population Council IncNew York, NY501(c)(3)Research & Development$36,925
Fred Hutchinson Cancer Reseach CenterSeattle, WA501(c)(3)Research & Development$19,309
PathWashington, DC-Research & Development$19,000
George Washington UniversityAshburn, VA501(c)(3)Research & Development$12,122
Abcam IncWaltham, MA-Research & Development$6,423

International Summary

Offices
2
Employees
36
Spending
$64,973,087

International Compliance

Foreign grant records maintained
Yes
Activity in boycott countries
No
Foreign corporation ownership
No
Foreign partnership interest
No
Interest in foreign trust
No
Passive foreign investment company interest
No
Transfers to foreign corporations
Yes

International Activities

RegionActivityServicesOfficesEmployeesSpending
North AmericaProgram Service ActivitiesResearch/advocacy/policy00$25,110,856
Sub-saharan AfricaGrants to Recipients Located in RegionResearch/advocacy/policy00$19,840,392
Europe (including Iceland & Greenland)Program Service ActivitiesResearch/advocacy/policy111$9,867,346
Europe (including Iceland & Greenland)Grants to Recipients Located in RegionResearch/advocacy/policy00$5,398,035
East Asia and the PacificProgram Service Activities-00$1,679,158
South AsiaProgram Service Activities-125$1,410,343
Sub-saharan AfricaProgram Service Activities-00$1,104,127
South AsiaGrants to Recipients Located in RegionResearch/advocacy/policy00$331,974
Middle East and North AfricaGrants to Recipients Located in RegionResearch/advocacy/policy00$170,827
Middle East and North AfricaProgram Service ActivitiesResearch/advocacy/policy00$38,948
South AmericaProgram Service Activities-00$21,081
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
Yes
Subject to proxy tax
No
Insider Transactions and Loans

Interested-Person Transactions

Interested PartyRelationshipDescriptionShared RevenueAmount
-An Iavi Board Member Is the Deputy Director and COO of the Entity.Iavi Has a Sub-award Agreement With Desmond Tutu Institute for Hiv Research Foundation.No$58,769
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Operating Lease Liabilities$29,628,865
Deferred Compensation Payable$500,200
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
Yes
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
Yes
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section B, Line 11B

The form 990 was reviewed in detail by the controller and cfo against the audited financial statements before filed with the irs. Please note that the financial statements are first reviewed and approved by the audit and finance committee and shared with the full board of directors.

Form 990, Part VI, Section B, Line 12C

Iavi has a conflict of interest policy which applies to all directors, officers, key persons, employees, consultants and advisory committee members. The policy requires that all directors, officers, key persons, employees and advisory committee members file an annual disclosure form, indicating whether there are any possible or actual conflicts as defined under the policy. In addition, all are required to disclose any possible or actual conflicts on an ongoing basis. Annual disclosure forms, as well other conflict of interest disclosures that arise during the year, are filed with and reviewed by the general counsel's office. In addition, the audit & finance committee reviews conflict of interest disclosures that involve a director, officer, or key person. In each case, the review ensures that any conflict of interest or possible conflict of interest is properly addressed, mitigated, and/or managed. Conflict of interest disclosures are summarized and provided to the chair of the audit & finance committee for review by the audit & finance committee. If any conflict of interest or possible conflict of interest disclosure involves the chair of the audit & finance committee, the committee meets without the chair.

Form 990, Part VI, Section B, Line 15

The compensation committee of the board can periodically commission a compensation survey of the ceo's compensation package. When done this survey compares compensation packages of ceos of organizations that are comparable to iavi. Then the committee reviews the results and makes recommendations, discusses this with the board before providing specific guidance and approval to iavi's management. The compensation committee determines the appropriate package for the ceo and the board chair shares this information with human resources for implementation. Iavi makes use of data from a specialized compensation firm to conduct the survey and provide recommendation to the compensation committee. The deliberations of the compensation committee of the board are documented in the compensation committee minutes for each meeting of the members. Also, the same is captured in the board minutes as reported out by the compensation committee chair for board discussions and approval. The last compensation review took place in december 2024. The committee had not requested a compensation survey specfic to ceo pay this year so management referenced extenral data sources to determine the competitive landscape and develop annual increase recommendations for the ceo and other key personnel. The committee reviews the results and recommendations from these sources and provides management with specific guidance in addressing any disparities. Using benchmark job classifications, iavi purchases external salary survey data, and uses this data across all its offices to determine the competitiveness of its compensation programs and to enable the organization to continue to attract and retain the right talent in these various markets. In most cases the local labor market is considered and for certain positions, regional markets must be targeted. Salary recommendations and external data trends may be reviewed with the compensation committee of the board, which gives management overall guidance on compensation direction. Based on recommendations and guidance of the compensation committee, the executive office and human resources communicate changes to any affected employees. Any compensation changes are determined based on external competiveness, relative internal value, individual performance, team dynamic, and iavi's ability to pay.

Form 990, Part VI, Section C, Line 19

The organization makes its governing documents, conflict of interest policy, and financial statements available on its website.

Filing and Contact Details

Filer

Filer Name
International Aids Vaccine
EIN
13-3870223
Phone
2128471111
Address
125 BROAD STREET 9TH FL, NEW YORK, NY 10004
Doing Business As
Iavi

Signing Officer

Name
Brandon Saft
Title
CFO
Phone
2128471111
Signed
2025-10-30
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Mark B Feinberg
Formed
1996
Legal Domicile
De
Voting Board Members
14
Independent Board Members
13
Employees
260
Volunteers
13

Preparer

Firm
Gelman Rosenberg & Freedman
Address
4550 MONTGOMERY AVE SUITE 800N, BETHESDA, MD 20814-2930
Preparer
Richard J Locastro CPA
Phone
3019519090
Supplemental Narrative

Additional Explanations

FORM 990, PART XI, LINE 9:

Foreign exchange gain -716,289. Currency translation 45,885.

Financial Statement Notes

PART XI, LINE 2D - OTHER ADJUSTMENTS:

Revenue of stichting international aids vaccine initiative 57,225. Included in consolidated audit report but excluded for iavi form 990 reporting purposes. Revenue of iavi india, included in consolidated audit 364,050. Report but excluded for iavi form 990 reporting purposes. Revenue of iavi-sa, included in consolidated audit 280,919. Report but excluded for form 990 reporting purposes. Revenue of iavi-africa, included in consolidated audit 843,544. Report but excluded for form 990 reporting purposes.

PART XI, LINE 4B - OTHER ADJUSTMENTS:

Inter-company revenue, eliminated in consolidated audit 198,635. Report but included in iavi, inc. Form 990.

PART XII, LINE 2D - OTHER ADJUSTMENTS:

Expenses of stichting international aids vaccine initiative 2,693,433. Included in consolidated audit report but excluded for iavi form 990 reporting purposes. Expenses of iavi india, included in consolidated audit 221,619. Report but excluded for form 990 reporting purposes. Expenses of iavi-sa, included in consolidated audit 4,125,216. Report but excluded for form 990 reporting purposes. Expenses of iavi-africa, included in consolidated audit 5,235,808. Report but excluded for form 990 reporting purposes.

PART XII, LINE 4B - OTHER ADJUSTMENTS:

Inter-company grant expenses, eliminated in consolidated 11,759,984. Audit report but included in iavi, inc. Form 990.

Raw XML AppendixShowing 400 of 1,496 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0RESEARCH AND DEVELOPMENT: THROUGH SCIENTIFIC AND CLINICAL RESEARCH IN AFRICA, INDIA, EUROPE, AND THE U.S., IAVI DEVELOPS VACCINES AND ANTIBODIES IN AND FOR THE DEVELOPING WORLD AND SEEKS TO ACCELERATE THEIR INTRODUCTION IN LOW-INCOME COUNTRIES. IAVI ADVANCES SCIENTIFIC DISCOVERY AND DEVELOPMENT BY FOSTERING UNIQUE COLLABORATIONS AMONG ACADEMIA, INDUSTRY, LOCAL COMMUNITIES, GOVERNMENTS, AND FUNDERS TO EXPLORE NEW AND BETTER WAYS TO ADDRESS PUBLIC HEALTH THREATS THAT DISPROPORTIONATELY AFFECT PEOPLE LIVING IN POVERTY. VACCINE AND ANTIBODY CANDIDATES ARE PUT THROUGH A RIGOROUS PROCESS OF CLINICAL EVALUATION AMONG KEY POPULATIONS TO ESTABLISH THEIR SAFETY AND EFFICACY, AN EFFORT THAT ENABLES IAVI TO STRENGTHEN THE HEALTHCARE INFRASTRUCTURE AND SCIENTIFIC CAPACITY OF COUNTRIES WHERE OUR CLINICAL PARTNERS OPERATE. TO DATE, IAVI AND ITS PARTNERS HAVE ADVANCED DOZENS OF HIV VACCINE CANDIDATES INTO EARLY-STAGE CLINICAL TRIALS, INCLUDING A VACCINE CANDIDATE THAT HAS YIELDED PROMISING EARLY RESULTS AND IS PART OF AN EXCITING NEW APPROACH TO HIV VACCINE DESIGN. OTHER NOTABLE ACHIEVEMENTS INCLUDE THE FIRST HIV VACCINE TRIALS IN SUB-SAHARAN COUNTRIES, WHERE HIV BURDEN IS GREATEST, AND THE FIRST TRIAL OF AN MRNA HIV VACCINE CANDIDATE IN AFRICA. IAVI HAS CONDUCTED MORE THAN 50 EPIDEMIOLOGICAL STUDIES AND PROVIDED VOLUNTARY HIV TESTING, COUNSELING SERVICES, AND HEALTH CARE REFERRALS TO MORE THAN 870,000 INDIVIDUALS IN AFRICA. IAVI ALSO SUPPORTS PRECLINICAL DEVELOPMENT AND CLINICAL TESTING OF VACCINE CANDIDATES FOR OTHER DISEASES, INCLUDING TUBERCULOSIS, LASSA FEVER, MARBURG, AND EBOLA SUDAN, AS WELL AS ANTIBODY CANDIDATES FOR DISEASE PREVENTION AND TREATMENT. IAVI CONDUCTS TRIALS WITH THE HIGHEST SCIENTIFIC AND ETHICAL STANDARDS TO PROTECT THE RIGHTS, WELL-BEING, AND DIGNITY OF TRIAL VOLUNTEERS. IAVI HAS ALSO LAUNCHED RESEARCH CONSORTIA TO ADDRESS MAJOR SCIENTIFIC PROBLEMS OF BIOMEDICAL PRODUCT DEVELOPMENT. A SIGNIFICANT PORTION OF RESEARCH IAVI SUPPORTS IS CONDUCTED IN LOW-INCOME COUNTRIES WHERE THE NEED FOR INFECTIOUS DISEASE PREVENTION IS GREATEST. IAVI ALSO SUPPORTS EXTERNAL RESEARCHERS BY PROVIDING TECHNICAL AND SCIENTIFIC EXPERTISE TO ACCELERATE THE DEVELOPMENT OF THEIR OWN PRODUCTS.
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IRS990/OtherExpensesGrp/Desc2EQUIPMENT MAINT.
IRS990/OtherExpensesGrp/Desc3OFFICE FURNITURE
IRS990/OtherExpensesGrp/ManagementAndGeneralAmt0473333
IRS990/OtherExpensesGrp/ManagementAndGeneralAmt122757
IRS990/OtherExpensesGrp/ProgramServicesAmt038907146
IRS990/OtherExpensesGrp/ProgramServicesAmt14779891
IRS990/OtherExpensesGrp/ProgramServicesAmt2801517
IRS990/OtherExpensesGrp/ProgramServicesAmt3288378
IRS990/OtherExpensesGrp/TotalAmt039380479

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