The Jackson Laboratory

“The chief operating officer position was eliminated from the officers of the laboratory section of the bylaws. An authorization for the board of trustees to vote by means of remote communication and conducting votes remotely was added to the bylaws. The vote conducted by electronic transmission and remotely must be filed with the minutes of any regular or duly called meeting and has the same effect as an in-person vote, and votes conducted remotely are counted for quorum purposes.”

“The audit and enterprise risk management committee of the jackson laboratory's board of trustees reviews a draft copy of the irs form 990 before it is provided to the board of trustees. After the audit and enterprise risk management committee's review, the irs form 990 is finalized and provided to the board of trustees prior to filing with the internal revenue service.”

“The jackson laboratory requests all officers, board members and key employees complete a "certification of compliance with conflict of interest policy and code of ethics" form and a "conflict of interest disclosure form" questionnaire, and distributes all policies regarding the conflict of interest and code of ethics. This process is done annually. The disclosure and compliance attestations are returned to the general counsel, where they are recorded and tallied for completeness. Disclosures, as well as any follow up questions, are routed through general counsel, and if necessary the audit and enterprise risk committee. Trustees and executives with an apparent or actual conflict of interest recuse themselves from decision making.”

“The compensation and human resources committee of the board of trustees sets compensation and benefits for the chief executive officer and the committee reviews the compensation and benefits for the officers and certain key employees listed in schedule j. Members of the committee are independent trustees selected by the chair of the board of trustees. The committee is guided by compensation market data for similar positions in comparable organizations. Market data is prepared for the committee by an external executive compensation firm which considers compensation information reported in form 990's of comparable organizations and the results of recognized compensation surveys. The chief human resources officer is available to the committee to provide any other data needed. The ceo and coo meets with the committee at least annually to review the compensation of their direct reports. The committee's review process and results are documented in minutes of the meetings.”

“The organization's form 990 is available on www.guidestar.org and on the organization's public website www.jax.org. The organization's financial statements are available at www.jax.org. The governing documents and conflict of interest policy are made available to the public upon request.”

“INTERCOMPANY TRANSACTION - Total Revenue: -1059405, Related or Exempt Function Revenue: -1059405, Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: ;”

“In 2024, approximately 450 mouse strains were donated to the laboratory or developed by jax research staff with academic/foundation or publicly funded research programs. The laboratory makes these resources publicly accessible through its repository, production and research services. Distribution of these strains helps support cures for the world's most prevalent human diseases and accelerates the time to bring new therapies to patients. The laboratory collaborated with other non-profit patient foundations for rare diseases to establish mouse resources to further preclinical therapeutic studies.”

“The purposes of the laboratory are scientific, medical, charitable, and educational to discover precise genomic solutions for disease and empower the biomedical community. To accomplish this mission, the laboratory: 1) conducts basic biomedical research to increase the knowledge of development, growth, reproduction, physiology, and pathophysiology through research with genetically defined experimental mouse models and other models of disease; 2) conducts translational biomedical research to identify the genomic impact on human disease, promote the establishment of more precise, targeted therapies, offer cutting edge genomic diagnostics to improve patient care, and provide advanced computational tools, databases and knowledge management systems to the biomedical research and medical communities; 3) trains and educates students, scientists, physicians, and other professionals in these areas; and 4) promotes scientific discovery through the provision of mouse models and other models of human disease and the provision of research, clinical, computational and information services to the global scientific and medical communities.”

“DEREGISTRATION OF JOINT VENTURE - -6834516; Total - -6834516;”