Civic Intelligence

Holobiont Medical Research Foundation

EIN 99-2133246 • 501(c)3 • San Francisco, CA

Profile

The holobiont medical research foundation is dedicated to advancing scientific knowledge and improving human health through research and innovation. Our mission is to unravel the intricate connections between the human microbiome, exposome and physiological processes within the human body that define health and well-being.

953 Indiana StreetSan Francisco, CA 94107

www.holobio.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

60th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2024

Liabilities / Revenue

62nd percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2024

Net Margin

52nd percentile

2.8%

Higher net margin than 52% of similar nonprofits.

501(c)3 • <$500k nonprofits • Source year 2024

Top Officer Pay

81st percentile

$0

Higher top officer pay than 81% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

501(c)3 • <$500k nonprofits • Source year 2024

Asset Growth

Score unavailable

No value available

No earlier valid filing was available within the previous three public years.

Source year 2024

Revenue Growth

Score unavailable

No value available

No earlier valid filing was available within the previous three public years.

Source year 2024

Balance Sheet
Liabilities / Assets60th percentile

Assets

$9,213

No earlier filing loaded for comparison.

Liabilities

$0

No earlier filing loaded for comparison.

Net Assets

$9,213

No earlier filing loaded for comparison.

Operations
Liabilities / Revenue62nd percentileNet Margin52nd percentile

Revenue

$335,001

No earlier filing loaded for comparison.

Expenses

$325,788

No earlier filing loaded for comparison.

Net Income

$9,213

No earlier filing loaded for comparison.

Trend Graphs

Balance Sheet Trend

Asset GrowthScore unavailable

Grouped bars show assets, liabilities, and net assets across loaded filings.

$10K$5.0K$0Assets 2024: $9,213Liabilities 2024: $0Net Assets 2024: $9,2132024

Highlighted filing

2024

Assets$9,213
Liabilities$0
Net Assets$9,213
Open 2024 Filing

Operations Trend

Revenue GrowthScore unavailable

Revenue, expenses, and net income by year, with the latest filing highlighted.

$400K$300K$200K$100K$0Revenue 2024: $335,001Expenses 2024: $325,788Net Income 2024: $9,2132024

Highlighted filing

2024

Revenue$335,001
Expenses$325,788
Net Income$9,213
Open 2024 Filing

Filings

Most recent year

2024 • Form 990Facts available. Structured filing facts are available, but richer extracted sections are limited.

Open filing
Assets
$9,213
Liabilities
$0
Net assets
$9,213
Revenue
$335,001
Expenses
$325,788
Net income
$9,213
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Facts available. Structured filing facts are available, but richer extracted sections are limited.$0.09$0.00$0.09$3.35$3.26$0.09
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Nov 17, 2025
Return Version
2024v5.2
Gross Receipts
$335,001
Mission and Program Overview

Mission

The holobiont medical research foundation is dedicated to advancing scientific knowledge and improving human health through research and innovation. Our mission is to unravel the intricate connections between the human microbiome, exposome and physiological processes within the human body that define health and well-being.

Balance Sheet Detail
LineBeginningEndChange
Assets
Savings and Temporary Cash Investments-$5,600-
Cash and Non-Interest-Bearing Accounts-$3,613-
Accounts Receivable-$0-
Other Notes and Loans Receivable, Net-$0-
Pledges and Grants Receivable-$0-
Receivable From Disqualified Prsn-$0-
Receivables From Officers Etc-$0-
Investments Other Securities-$0-
Investments Program Related-$0-
Investments in Publicly Traded Securities-$0-
Land, Buildings, and Equipment, Net-$0-
Intangible Assets-$0-
Inventories for Sale or Use-$0-
Prepaid Expenses and Deferred Charges-$0-
Total Assets$0$9,213▲ $9,213
Other Assets Total-$0-
Liabilities
Total Liabilities$0$0→ $0
Net Assets / Fund Balance
Net Assets Without Donor Restrictions-$9,213-
Total Net Assets Fund Balance$0$9,213▲ $9,213
Total Liabilities and Net Assets / Fund Balance$0$9,213▲ $9,213
Compensation and Service Providers
Top Officer Pay81st percentile

Board Members and Trustees

NameTitle
Larry WeissPresident
Julia DurackVice President
Howard MaibachDirector
Carlos BustamanteSecretary
Rita ColwellTreasurer
Revenue and Support

Revenue Composition

Contributions and Grants
$335,000
Program Service Revenue
$0
Investment Income
$1
Other Revenue
$0
All Other Contributions
$335,000
Change in Net Assets
$9,213
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$301,770
Other Expenses$24,018
Total Fundraising Expense$16,000
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$301,770--$301,770
Office Expenses-$4,715-$4,715
Fees for Services Other-$1,352-$1,352
Travel-$1,045-$1,045
Other Expenses-$906$16,000$906
Total Functional Expenses$301,770$8,018$16,000$325,788
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
Weiss Bioscience IncSan Francisco, CA-Medical Research$250,770
Biomemimetics LLCSan Francisco, CA-Medical Research$51,000
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Receivables from Disqualified Persons-$0-
Receivables from Officers, Directors, Trustees, and Key Employees-$0-
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Backup withholding compliance
No
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
No
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

“Larry weiss and julia durack are 50/50 members in biomemimetics, llc.”

Form 990, Part VI, Section B, Line 11B

“A draft of the return is provided to the Board of Directors for review. Each director is given an opportunity to ask questions and request revisions before the return is finalized and filed.”

Form 990, Part VI, Section C, Line 19

“No documents available to the public.”

Filing and Contact Details

Filer

Filer Name
Holobiont Medical Research Foundation
EIN
99-2133246
Phone
4152233901
Address
953 INDIANA STREET, SAN FRANCISCO, CA 94107

Signing Officer

Name
Larry Weiss
Title
President
Signed
2025-11-17
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Larry Weiss
Formed
2024
Legal Domicile
CA
Voting Board Members
5
Independent Board Members
3
Employees
0

Preparer

Firm
Bregante Company Llp Cpas
Address
50 CALIFORNIA STREET SUITE 1500, SAN FRANCISCO, CA 94111
Preparer
Jennifer L Ruth
Phone
4157771001
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This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt0LARRY WEISS AND JULIA DURACK ARE 50/50 MEMBERS IN BIOMEMIMETICS, LLC.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt1A draft of the return is provided to the Board of Directors for review. Each director is given an opportunity to ask questions and request revisions before the return is finalized and filed.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt2No documents available to the public.
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc0Form 990, Part VI, Section A, Line 2
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc1Form 990, Part VI, Section B, Line 11b
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc2Form 990, Part VI, Section C, Line 19
IRS990/SchoolOperatingInd0false
IRS990/SignificantChangeInd0false
IRS990/SignificantNewProgramSrvcInd0false
IRS990/StatesWhereCopyOfReturnIsFldCd0CA
IRS990/SubjectToExcsTaxNetInvstIncInd0false
IRS990/SubjectToProxyTaxInd0false
IRS990/SubjToTaxRmnrtnExPrchtPymtInd0false
IRS990/TaxablePartyNotificationInd0false
IRS990/TaxExemptBondsInd0false
IRS990/TerminateOperationsInd0false
IRS990/TotalAssetsEOYAmt09213
IRS990/TotalAssetsGrp/BOYAmt00
IRS990/TotalAssetsGrp/EOYAmt09213
IRS990/TotalCompGreaterThan150KInd0false
IRS990/TotalContributionsAmt0335000
IRS990/TotalEmployeeCnt00
IRS990/TotalFunctionalExpensesGrp/FundraisingAmt016000
IRS990/TotalFunctionalExpensesGrp/ManagementAndGeneralAmt08018
IRS990/TotalFunctionalExpensesGrp/ProgramServicesAmt0301770
IRS990/TotalFunctionalExpensesGrp/TotalAmt0325788
IRS990/TotalGrossUBIAmt00
IRS990/TotalLiabilitiesEOYAmt00
IRS990/TotalLiabilitiesGrp/BOYAmt00
IRS990/TotalLiabilitiesGrp/EOYAmt00
IRS990/TotalNetAssetsFundBalanceGrp/BOYAmt00
IRS990/TotalNetAssetsFundBalanceGrp/EOYAmt09213
IRS990/TotalProgramServiceExpensesAmt0301770
IRS990/TotalProgramServiceRevenueAmt00
IRS990/TotalRevenueGrp/ExclusionAmt01
IRS990/TotalRevenueGrp/TotalRevenueColumnAmt0335001
IRS990/TotLiabNetAssetsFundBalanceGrp/BOYAmt00
IRS990/TotLiabNetAssetsFundBalanceGrp/EOYAmt09213
IRS990/TravelGrp/ManagementAndGeneralAmt01045
IRS990/TravelGrp/TotalAmt01045
IRS990/TrnsfrExmptNonChrtblRltdOrgInd0false
IRS990/TypeOfOrganizationCorpInd0X
IRS990/UnrelatedBusIncmOverLimitInd0false
IRS990/UponRequestInd0X
IRS990/USAddress/AddressLine1Txt0953 INDIANA STREET
IRS990/USAddress/CityNm0SAN FRANCISCO
IRS990/USAddress/StateAbbreviationCd0CA
IRS990/USAddress/ZIPCd094107
IRS990/VotingMembersGoverningBodyCnt05
IRS990/VotingMembersIndependentCnt03
IRS990/WebsiteAddressTxt0WWW.HOLOBIO.ORG
IRS990/WhistleblowerPolicyInd0false
ReturnHeader/BuildTS02025-03-06 01:10:19Z
ReturnHeader/BusinessOfficerGrp/DiscussWithPaidPreparerInd0true
ReturnHeader/BusinessOfficerGrp/PersonNm0LARRY WEISS
ReturnHeader/BusinessOfficerGrp/PersonTitleTxt0President
ReturnHeader/BusinessOfficerGrp/SignatureDt02025-11-17
ReturnHeader/Filer/BusinessName/BusinessNameLine1Txt0HOLOBIONT MEDICAL RESEARCH FOUNDATION
ReturnHeader/Filer/BusinessNameControlTxt0HOLO
ReturnHeader/Filer/EIN0992133246
ReturnHeader/Filer/PhoneNum04152233901
ReturnHeader/Filer/USAddress/AddressLine1Txt0953 INDIANA STREET
ReturnHeader/Filer/USAddress/CityNm0SAN FRANCISCO
ReturnHeader/Filer/USAddress/StateAbbreviationCd0CA
ReturnHeader/Filer/USAddress/ZIPCd094107
ReturnHeader/IRSResponsiblePrtyInfoCurrInd0true
ReturnHeader/PreparerFirmGrp/PreparerFirmEIN0942861940
ReturnHeader/PreparerFirmGrp/PreparerFirmName/BusinessNameLine1Txt0BREGANTE COMPANY LLP CPAS
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/AddressLine1Txt050 CALIFORNIA STREET SUITE 1500
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/CityNm0SAN FRANCISCO
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/StateAbbreviationCd0CA
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/ZIPCd094111
ReturnHeader/PreparerPersonGrp/PhoneNum04157771001
ReturnHeader/PreparerPersonGrp/PreparerPersonNm0Jennifer L Ruth
ReturnHeader/ReturnTs02025-11-17T05:40:40-08:00
ReturnHeader/ReturnTypeCd0990
ReturnHeader/TaxPeriodBeginDt02024-01-01
ReturnHeader/TaxPeriodEndDt02024-12-31
ReturnHeader/TaxYr02024

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