Form 990, Part VI, Section B, Line 11B
“A copy of the Form 990 was provided to the officers and directors for review and comment prior to filing.”
Active Site Research Inc
EIN 93-2180352 • 501(c)3 • Cambridge, MA
NTEE H99
Profile
To eliminate the risks posed by pandemic threats through the advancement of science and innovation in medical countermeasure development, ensuring the health and well-being of individuals and communities worldwide.
Siviq Scores
Scores are not available for this record yet.
Balance Sheet
Assets
Up$1,352,366
Up $1,225,539 (+966%) from 2024
Liabilities
Up$37,462
Up $19,911 (+113%) from 2024
Net Assets
Up$1,314,904
Up $1,205,628 (+1103%) from 2024
Operations
Revenue
Up$2,258,848
Up $1,404,513 (+164%) from 2024
Expenses
Up$1,053,220
Up $308,161 (+41%) from 2024
Net Income
Up$1,205,628
Up $1,096,352 (+1003%) from 2024
Trend Graphs
Filings
Most recent year
2025 • Form 990Detailed filing. Detailed filing data is available for this year.
- Assets
- $1,352,366
- Liabilities
- $37,462
- Net assets
- $1,314,904
- Revenue
- $2,258,848
- Expenses
- $1,053,220
- Net income
- $1,205,628
Latest Filing Detail
Jump To
Filing Snapshot
- Filing Period
- Jun 1, 2024 to May 31, 2025
- Signed
- Mar 18, 2026
- Return Version
- 2024v5.2
- Gross Receipts
- $2,258,848
Mission and Program Overview
Mission
To eliminate the risks posed by pandemic threats through the advancement of science and innovation in medical countermeasure development, ensuring the health and well-being of individuals and communities worldwide.
Balance Sheet Detail
| Line | Beginning | End | Change |
|---|---|---|---|
| Assets | |||
| Cash and Non-Interest-Bearing Accounts | $90,453 | $1,046,342 | ▲ $955,889 |
| Pledges and Grants Receivable | - | $225,000 | - |
| Prepaid Expenses and Deferred Charges | $36,374 | $81,024 | ▲ $44,650 |
| Savings and Temporary Cash Investments | - | $0 | - |
| Accounts Receivable | - | $0 | - |
| Other Notes and Loans Receivable, Net | - | $0 | - |
| Receivable From Disqualified Prsn | - | $0 | - |
| Receivables From Officers Etc | - | $0 | - |
| Investments Other Securities | - | $0 | - |
| Investments Program Related | - | $0 | - |
| Investments in Publicly Traded Securities | - | $0 | - |
| Land, Buildings, and Equipment, Net | - | $0 | - |
| Intangible Assets | - | $0 | - |
| Inventories for Sale or Use | - | $0 | - |
| Total Assets | $126,827 | $1,352,366 | ▲ $1,225,539 |
| Other Assets Total | - | $0 | - |
| Liabilities | |||
| Accounts Payable and Accrued Expenses | $17,551 | $37,462 | ▲ $19,911 |
| Total Liabilities | $17,551 | $37,462 | ▲ $19,911 |
| Net Assets / Fund Balance | |||
| Net Assets With Donor Restrictions | - | $988,710 | - |
| Net Assets Without Donor Restrictions | $109,276 | $326,194 | ▲ $216,918 |
| Total Net Assets Fund Balance | $109,276 | $1,314,904 | ▲ $1,205,628 |
| Total Liabilities and Net Assets / Fund Balance | $126,827 | $1,352,366 | ▲ $1,225,539 |
Compensation and Service Providers
Employees
| Name | Title | Full / Part Time | Base | Other | Total |
|---|---|---|---|---|---|
| Brian Wang VP thru 3-2025 | Vice President | FT | $74,776 | $8,719 | $83,495 |
| Alexander Kleinman beg 3-2025 | Treasurer | FT | $69,802 | $8,154 | $77,956 |
| Joe Torres beg 3-2025 | President | FT | $75,000 | - | $75,000 |
Board Members and Trustees
| Name | Title |
|---|---|
| Ales Flidr | Chairman |
| Jacob Swett | Director |
| William Bradshaw | Secretary |
Revenue and Support
Revenue Composition
- Contributions and Grants
- $2,215,714
- Program Service Revenue
- $37,893
- Investment Income
- $0
- Other Revenue
- $5,241
- All Other Contributions
- $2,215,714
- Change in Net Assets
- $1,205,628
Audited Revenue Reconciliation
- Revenue per Audited Statements
- $2,258,848
- Total Revenue per Audited Statements
- $2,258,848
- Total Revenue per Form 990
- $2,258,848
Expenses and Functional Allocation
Major Expense Lines
| Line Item | Amount |
|---|---|
| Other Expenses | $752,078 |
| Salaries, Compensation, and Employee Benefits | $301,142 |
| Total Fundraising Expense | $21,129 |
| Grants and Similar Amounts Paid | $0 |
| Professional Fundraising Fees | $0 |
Functional Expense Allocation
| Line Item | Program | Management | Fundraising | Total |
|---|---|---|---|---|
| Current Officers, Directors, Trustees, and Key Employees | $182,376 | $31,911 | $11,989 | $226,276 |
| Occupancy | $61,954 | $94,999 | $1,696 | $158,649 |
| Other Salaries and Wages | $42,232 | $7,191 | $2,602 | $52,025 |
| Fees for Services Other | $35,188 | $7,100 | $500 | $42,788 |
| Fees for Services Accounting | - | $25,420 | - | $25,420 |
| Payroll Taxes | $17,651 | $2,916 | $1,084 | $21,651 |
| Office Expenses | $15,269 | $5,977 | - | $21,246 |
| Advertising | $3,435 | $12,516 | $52 | $16,003 |
| Fees for Services Legal | $111 | $14,120 | - | $14,231 |
| Information Technology | $4,897 | $7,729 | - | $12,626 |
| Travel | $1,541 | $2,115 | $3,125 | $6,781 |
| Insurance | - | $3,940 | - | $3,940 |
| Other Expenses | $3,000 | $3,018 | - | $3,018 |
| All Other Expenses | $733 | $939 | - | $1,672 |
| Other Employee Benefits | $870 | $239 | $81 | $1,190 |
| Total Functional Expenses | $810,587 | $221,504 | $21,129 | $1,053,220 |
Audited Expense Reconciliation
| Line Item | Amount |
|---|---|
| Expenses per Audited Statements | $1,053,220 |
| Total Expenses per Audited Statements | $1,053,220 |
| Total Expenses per Form 990 | $1,053,220 |
Fundraising, Events, and Gaming
- Fundraising activities
- No
- Gaming activities
- No
- Professional fundraiser used
- No
Fundraising and Gaming Totals
| Line Item | Amount |
|---|---|
| Professional Fundraising Fees | $0 |
Political and Lobbying Activity
- Political campaign activity
- No
- Lobbying activity
- No
- Subject to proxy tax
- No
Insider Transactions and Loans
Loans and Receivables
| Line Item | Beginning | End | Change |
|---|---|---|---|
| Receivables from Disqualified Persons | - | $0 | - |
| Receivables from Officers, Directors, Trustees, and Key Employees | - | $0 | - |
Governance and Compliance
Governance Checklist
- Compiled or reviewed by an accountant
- No
- Annual disclosure for covered persons
- Yes
- Audit committee
- Yes
- Backup withholding compliance
- Yes
- Business relationship with 35% controlled entity
- No
- Business relationship with family members
- No
- Business relationship with organization members
- No
- Material changes to governing documents
- No
- Compensation from other sources disclosed
- No
- CEO compensation reviewed
- Yes
- Other officer compensation reviewed
- Yes
- Conflict-of-interest policy
- Yes
- Audited financial statements prepared
- No
- Key decisions subject to board approval
- No
- Management duties delegated
- No
Governance Explanations
Form 990, Part VI, Section B, Line 12C
“Upon engagement, election, or hiring, directors, officers, and key employees agree to comply with the conflict of interest policy and to disclose any conflicts of interest, which are then handled in accordance with the policy.”
Form 990, Part VI, Section B, Line 15A
“It is the organization's policy that compensation of any director, officer, or key employee is reasonable. Accordingly, compensation of the executive director was determined based on relevant comparability data followed by written resolution of a disinterested board approving the compensation in compliance with Treas. Reg. 53.4958-6.”
Form 990, Part VI, Section B, Line 15B
“See response to Form 990, Part VI, Line 15a.”
Form 990, Part VI, Section C, Line 18
“The organization's Form 1023 and Form 990 returns are accessible to the public through the California Attorney General Charities Registry. The organization can also make such documents available upon written request.”
Form 990, Part VI, Section C, Line 19
“Documents subject to public disclosure or inspection are accessible through the California Attorney General Charities Registry or can be made available upon written request to the organization.”
Filing and Contact Details
Filer
- Filer Name
- Active Site Research Inc
- EIN
- 93-2180352
- Phone
- 6174175428
- Address
- 1 Broadway Suite 13-100, Cambridge, MA 02142
Signing Officer
- Name
- Joe Torres
- Title
- President
- Signed
- 2026-03-18
- Discuss with paid preparer
- Yes
Organization Details
- Principal Officer
- Joe Torres
- Formed
- 2023
- Legal Domicile
- De
- Voting Board Members
- 4
- Independent Board Members
- 3
- Employees
- 11
Preparer
- Firm
- Tovella Dowling PC
- Address
- 501 W Broadway Ste 1540, San Diego, CA 92101
- Preparer
- Julie U Nguyen Esq
- Phone
- 6199309332
Supplemental Narrative
Additional Explanations
Form 990, Part III, Line 2
“began the PAN-2025-001 and AI/biosecurity programs (see Form 990, Part III, Lines 4b and 4c for program description)”
Form 990, Part III, Line 3
“Discontinued synthetic innate immunity program (see form 990, Part III, Line 4a for program description)”
Financial Statement Notes
Part X : FIN48 Footnote
“The Organization is a not-for-profit organization that has tax-exempt status under the provisions of the Internal Revenue Code section 501(c)(3). Net income from activities unrelated to the Organization's tax-exempt purpose is subject to taxation. The Organization had no significant unrelated business income during the year ended May 31, 2025, or during the period from inception (June 29, 2023) to May 31, 2024, and accordingly, no provision for income taxes has been made in the accompanying financial statements. The Organization annually files IRS Form 990 - Return of Organization Exempt from Income Tax reporting various information that the IRS uses to monitor the activities of tax-exempt entities. There were no tax penalties or interest recognized during the period or accrued at period end.”
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| IRS990/ProgramServiceRevenueGrp/Desc | 0 | AI/Biosecurity Services |
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| IRS990/ProgSrvcAccomActy2Grp/Desc | 0 | PAN-2025-001 is a single-site, two-arm, parallel-group superiority randomized controlled trial (RCT) with 1:1 allocation, designed to evaluate whether large language model (LLM) use improves the ability of novice lab participants to independently perform complex biological tasks. Participants attempt a fixed sequence of five laboratory obstacles that represent the core skills required to create a virus via reverse genetics with or without LLM assistance. |
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| IRS990/ProgSrvcAccomActy3Grp/Desc | 0 | The organization periodically provides subject-matter expertise in molecular biology and related life sciences disciplines to AI companies. Such services include responding to technical inquiries and developing advanced scientific problem sets designed to evaluate complex biological reasoning and analytical capabilities in emerging AI technologies. These activities further the organizations scientific research mission and promote the responsible development and evaluation of AI tools. |
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| IRS990ScheduleD/SupplementalInformationDetail/ExplanationTxt | 0 | The Organization is a not-for-profit organization that has tax-exempt status under the provisions of the Internal Revenue Code section 501(c)(3). Net income from activities unrelated to the Organization's tax-exempt purpose is subject to taxation. The Organization had no significant unrelated business income during the year ended May 31, 2025, or during the period from inception (June 29, 2023) to May 31, 2024, and accordingly, no provision for income taxes has been made in the accompanying financial statements. The Organization annually files IRS Form 990 - Return of Organization Exempt from Income Tax reporting various information that the IRS uses to monitor the activities of tax-exempt entities. There were no tax penalties or interest recognized during the period or accrued at period end. |
| IRS990ScheduleD/SupplementalInformationDetail/FormAndLineReferenceDesc | 0 | Part X : FIN48 Footnote |
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| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 0 | began the PAN-2025-001 and AI/biosecurity programs (see Form 990, Part III, Lines 4b and 4c for program description) |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 1 | Discontinued synthetic innate immunity program (see form 990, Part III, Line 4a for program description) |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 2 | A copy of the Form 990 was provided to the officers and directors for review and comment prior to filing. |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 3 | Upon engagement, election, or hiring, directors, officers, and key employees agree to comply with the conflict of interest policy and to disclose any conflicts of interest, which are then handled in accordance with the policy. |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 4 | It is the organization's policy that compensation of any director, officer, or key employee is reasonable. Accordingly, compensation of the executive director was determined based on relevant comparability data followed by written resolution of a disinterested board approving the compensation in compliance with Treas. Reg. 53.4958-6. |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 5 | See response to Form 990, Part VI, Line 15a. |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 6 | The organization's Form 1023 and Form 990 returns are accessible to the public through the California Attorney General Charities Registry. The organization can also make such documents available upon written request. |
| IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt | 7 | Documents subject to public disclosure or inspection are accessible through the California Attorney General Charities Registry or can be made available upon written request to the organization. |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 0 | Form 990, Part III, Line 2 |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 1 | Form 990, Part III, Line 3 |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 2 | Form 990, Part VI, Section B, Line 11b |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 3 | Form 990, Part VI, Section B, Line 12c |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 4 | Form 990, Part VI, Section B, Line 15a |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 5 | Form 990, Part VI, Section B, Line 15b |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 6 | Form 990, Part VI, Section C, Line 18 |
| IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc | 7 | Form 990, Part VI, Section C, Line 19 |
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