Liabilities / Assets
42nd percentile
Higher debt load relative to assets than 42% of similar nonprofits.
EIN 87-1876876 • 501(c)3 • New York, NY
Profile
The purposes for which the foundation is formed are to address the unmet medical needs of patiens with polg-related disorders with the goal of being able to mitigate or cure such disorders. The foundation intends to (i) identify high-quality scientific research and discoveries in the treatment and diagnosis of polg-related disorders, (ii) provide capital to assist in the development of new treatments and diagnostic tools for such disorders; and (iii) fund research [and] clinical trials, and invest in mission-related business.
Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.
Liabilities / Assets
42nd percentile
Higher debt load relative to assets than 42% of similar nonprofits.
Liabilities / Revenue
77th percentile
Higher debt load relative to revenue than 77% of similar nonprofits.
Net Margin
3rd percentile
Higher net margin than 3% of similar nonprofits.
Top Officer Pay
Score unavailable
No filing with officer rows is available for this organization yet.
Asset Growth
14th percentile
Faster asset growth than 14% of similar nonprofits.
Revenue Growth
1st percentile
Faster revenue growth than 1% of similar nonprofits.
Assets
Down$6,529,501
Down $998,734 (-13%) from 2023
Liabilities
Down$448,201
Down $139,761 (-24%) from 2023
Net Assets
Down$6,081,300
Down $858,973 (-12%) from 2023
Revenue
Up$1,297,847
Up $314,336 (+32%) from 2023
Expenses
Up$2,097,172
Up $9,481 (+0.5%) from 2023
Net Income
Up-$799,325
Up $304,855 (+28%) from 2023
Most recent year
2024 • Form 990Detailed filing. Detailed filing data is available for this year.
The purposes for which the Foundation is formed are to address the unmet medical needs of patients with PolG-related disorders with the goal of being able to mitigate or cure such disorders. The foundation intends to (i) identify high-quality scientific research and discoveries in the treatment and diagnosis of PolG-related disorders, (ii) provide capital to assist in the development of new treatments and diagnostic tools for such disorders; and (iii) fund research [and] clinical trials, and invest in mission-related businesses.
Support research to find treatments and a cure for polg-related mitochondrial disorders.
| Line | Beginning | End | Change |
|---|---|---|---|
| Assets | |||
| Investments in Publicly Traded Securities | $4,764,360 | $4,474,729 | ▼ $289,631 |
| Cash and Non-Interest-Bearing Accounts | $1,589,858 | $1,029,526 | ▼ $560,332 |
| Investments Other Securities | $942,997 | $925,246 | ▼ $17,751 |
| Pledges and Grants Receivable | $223,020 | $100,000 | ▼ $123,020 |
| Savings and Temporary Cash Investments | - | $0 | - |
| Accounts Receivable | - | $0 | - |
| Other Notes and Loans Receivable, Net | - | $0 | - |
| Receivable From Disqualified Prsn | - | $0 | - |
| Receivables From Officers Etc | - | $0 | - |
| Investments Program Related | - | $0 | - |
| Land, Buildings, and Equipment, Net | - | $0 | - |
| Intangible Assets | - | $0 | - |
| Inventories for Sale or Use | - | $0 | - |
| Prepaid Expenses and Deferred Charges | - | $0 | - |
| Total Assets | $7,528,235 | $6,529,501 | ▼ $998,734 |
| Other Assets Total | $8,000 | $0 | ▼ $8,000 |
| Liabilities | |||
| Grants Payable | $569,926 | $429,788 | ▼ $140,138 |
| Accounts Payable and Accrued Expenses | $18,036 | $18,413 | ▲ $377 |
| Total Liabilities | $587,962 | $448,201 | ▼ $139,761 |
| Net Assets / Fund Balance | |||
| Net Assets Without Donor Restrictions | $6,740,273 | $5,981,300 | ▼ $758,973 |
| Net Assets With Donor Restrictions | $200,000 | $100,000 | ▼ $100,000 |
| Total Net Assets Fund Balance | $6,940,273 | $6,081,300 | ▼ $858,973 |
| Total Liabilities and Net Assets / Fund Balance | $7,528,235 | $6,529,501 | ▼ $998,734 |
| Name | Title | Full / Part Time | Base | Total |
|---|---|---|---|---|
| Samuel Seward | Executive Director | FT | $196,923 | $196,923 |
| Brian Tseng | Director | FT | $149,813 | $149,813 |
| Name | Title |
|---|---|
| Robert De Luxembourg | Chairman |
| Julie De Luxembourg | Vice Chair |
| Allyson Ocean | Director |
| Cindy Gavin | Director |
| Francesco De Rubertis | Director |
| Jennifer Adams | Director |
| Jrg Duschmale | Director |
| Remy Best | Director |
| Stven Altschuler | Director |
| Eileen Kane | Corp. Secretary |
| Marcus Siezing | Treasurer |
| Contractor | Services | Location | Compensation |
|---|---|---|---|
| Brian Tseng | Outsourced Research | PO Box 3791, Estes Park, CO 80517 | $149,813 |
| Contribution Type | Contribution Count | Reported Amount | Valuation Method |
|---|---|---|---|
| Securities Publicly Traded | 1 | $100,266 | Fair Market Value (FMV) |
| Total Noncash Contributions | 1 | $100,266 | - |
| Line Item | Amount |
|---|---|
| Grants and Similar Amounts Paid | $1,327,408 |
| Other Expenses | $557,444 |
| Salaries, Compensation, and Employee Benefits | $212,320 |
| Professional Fundraising Fees | $0 |
| Total Fundraising Expense | $0 |
| Line Item | Program | Management | Fundraising | Total |
|---|---|---|---|---|
| Grants to Domestic Orgs | $666,554 | - | - | $666,554 |
| Foreign Grants | $660,854 | - | - | $660,854 |
| Fees for Services Other | $246,686 | $91,400 | - | $338,086 |
| Current Officers, Directors, Trustees, and Key Employees | $196,923 | - | - | $196,923 |
| Fees for Services Accounting | $58,500 | $21,675 | - | $80,175 |
| Conferences and Meetings | $32,806 | - | - | $32,806 |
| Travel | $32,784 | - | - | $32,784 |
| Payroll Taxes | $15,397 | - | - | $15,397 |
| Other Expenses | $21,590 | $10,685 | - | $10,685 |
| Fees for Services Legal | $3,559 | $1,319 | - | $4,878 |
| Advertising | $4,057 | - | - | $4,057 |
| Total Functional Expenses | $1,963,560 | $133,612 | $0 | $2,097,172 |
| Line Item | Amount |
|---|---|
| Expenses per Audited Statements | $2,097,172 |
| Total Expenses per Audited Statements | $2,097,172 |
| Total Expenses per Form 990 | $2,097,172 |
| Recipient | Location | Category | Purpose | Amount |
|---|---|---|---|---|
| The Broad Institute | Cambridge, MA | - | Variant-to-function map of POLG | $310,000 |
| The Broad Institute | Cambridge, MA | - | Variant-to-function map of POLG | $305,000 |
| Columbia University IMC | New York, NY | - | Report of post-mortem analysis | $25,000 |
| Childrens Hospital of PA | Philadelphia, PA | - | POLG Retrospective Data Query | $13,262 |
| Childrens Hospital of PA | Philadelphia, PA | - | POLG Retrospective Data Query | $13,262 |
| Region | Activity | Services | Offices | Employees | Spending |
|---|---|---|---|---|---|
| Europe | Research Grant | Research Grant | 0 | 0 | $660,854 |
| Line Item | Amount |
|---|---|
| Professional Fundraising Fees | $0 |
| Line Item | Beginning | End | Change |
|---|---|---|---|
| Receivables from Disqualified Persons | - | $0 | - |
| Receivables from Officers, Directors, Trustees, and Key Employees | - | $0 | - |
“Robert and julie de luxembourg are married.”
“Management reviewed a draft of the form 990 with the treasurer and secretary and provided edits to the tax preparer. After this process was performed, the form 990 was sent to the full board of directors prior to being filed with the irs.”
“The organization has a written conflict of interest policy. The written policy requires disclosures by all members of the board of directors, officers and employees of the organzation that could give rise to conflict. The organization regularly monitors and enforces the compliance of the conflict of interest policy. There were no conflicts of interest for the tax year ended december 31, 2024.”
“AVAILABLE UPON REQUEST.”
“The foundation does not believe its financial statements include any material, uncertain tax positions. Tax filings for the period ended december 31, 2021, the foundation's initial filing, and later are subject to examination by applicable taxing authorities.”
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990/Form990PartVIISectionAGrp/TitleTxt | 3 | Vice Chair |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 4 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 5 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 6 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 7 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 8 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 9 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 10 | Director |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 11 | Corp. Secretary |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 12 | Treasurer |
| IRS990/Form990ProvidedToGvrnBodyInd | 0 | true |
| IRS990/FormationYr | 0 | 2021 |
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| IRS990/FSAuditedInd | 0 | true |
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| IRS990/GamingActivitiesInd | 0 | false |
| IRS990/GoverningBodyVotingMembersCnt | 0 | 10 |
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| IRS990/GrantsPayableGrp/EOYAmt | 0 | 429788 |
| IRS990/GrantsToDomesticIndividualsGrp/TotalAmt | 0 | 0 |
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| IRS990/GrantsToDomesticOrgsGrp/TotalAmt | 0 | 666554 |
| IRS990/GrantsToIndividualsInd | 0 | false |
| IRS990/GrantsToOrganizationsInd | 0 | true |
| IRS990/GrantToRelatedPersonInd | 0 | false |
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| IRS990/GrossReceiptsAmt | 0 | 3072175 |
| IRS990/GroupReturnForAffiliatesInd | 0 | false |
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| IRS990/IndependentAuditFinclStmtInd | 0 | true |
| IRS990/IndependentVotingMemberCnt | 0 | 8 |
| IRS990/IndivRcvdGreaterThan100KCnt | 0 | 2 |
| IRS990/IndoorTanningServicesInd | 0 | false |
| IRS990/InfoInScheduleOPartIXInd | 0 | X |
| IRS990/InfoInScheduleOPartVIInd | 0 | X |
| IRS990/InformationTechnologyGrp/TotalAmt | 0 | 0 |
| IRS990/InsuranceGrp/TotalAmt | 0 | 0 |
| IRS990/IntangibleAssetsGrp/EOYAmt | 0 | 0 |
| IRS990/InterestGrp/TotalAmt | 0 | 0 |
| IRS990/InventoriesForSaleOrUseGrp/EOYAmt | 0 | 0 |
| IRS990/InvestmentIncomeGrp/ExclusionAmt | 0 | 235293 |
| IRS990/InvestmentIncomeGrp/TotalRevenueColumnAmt | 0 | 235293 |
| IRS990/InvestmentInJointVentureInd | 0 | false |
| IRS990/InvestmentsOtherSecuritiesGrp/BOYAmt | 0 | 942997 |
| IRS990/InvestmentsOtherSecuritiesGrp/EOYAmt | 0 | 925246 |
| IRS990/InvestmentsProgramRelatedGrp/EOYAmt | 0 | 0 |
| IRS990/InvestmentsPubTradedSecGrp/BOYAmt | 0 | 4764360 |
| IRS990/InvestmentsPubTradedSecGrp/EOYAmt | 0 | 4474729 |
| IRS990/IRPDocumentCnt | 0 | 3 |
| IRS990/IRPDocumentW2GCnt | 0 | 0 |
| IRS990/LandBldgEquipBasisNetGrp/EOYAmt | 0 | 0 |
| IRS990/LegalDomicileStateCd | 0 | DE |
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| IRS990/LoanOutstandingInd | 0 | false |
| IRS990/LobbyingActivitiesInd | 0 | false |
| IRS990/LocalChaptersInd | 0 | false |
| IRS990/MaterialDiversionOrMisuseInd | 0 | false |
| IRS990/MembersOrStockholdersInd | 0 | false |
| IRS990/MethodOfAccountingAccrualInd | 0 | X |
| IRS990/MinutesOfCommitteesInd | 0 | true |
| IRS990/MinutesOfGoverningBodyInd | 0 | true |
| IRS990/MissionDesc | 0 | THE PURPOSES FOR WHICH THE FOUNDATION IS FORMED ARE TO ADDRESS THE UNMET MEDICAL NEEDS OF PATIENS WITH POLG-RELATED DISORDERS WITH THE GOAL OF BEING ABLE TO MITIGATE OR CURE SUCH DISORDERS. THE FOUNDATION INTENDS TO (I) IDENTIFY HIGH-QUALITY SCIENTIFIC RESEARCH AND DISCOVERIES IN THE TREATMENT AND DIAGNOSIS OF POLG-RELATED DISORDERS, (II) PROVIDE CAPITAL TO ASSIST IN THE DEVELOPMENT OF NEW TREATMENTS AND DIAGNOSTIC TOOLS FOR SUCH DISORDERS; AND (III) FUND RESEARCH [AND] CLINICAL TRIALS, AND INVEST IN MISSION-RELATED BUSINESS. |
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| IRS990/MoreThan5000KToOrgInd | 0 | false |
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| IRS990/NetGainOrLossInvestmentsGrp/TotalRevenueColumnAmt | 0 | 110856 |
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| IRS990/NetIncomeFromGamingGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetIncomeOrLossGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetRentalIncomeOrLossGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetUnrlzdGainsLossesInvstAmt | 0 | -59648 |
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| IRS990/NoDonorRestrictionNetAssetsGrp/EOYAmt | 0 | 5981300 |
| IRS990/NoncashContributionsAmt | 0 | 100266 |
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| IRS990/OfficeExpensesGrp/TotalAmt | 0 | 0 |
| IRS990/OfficerMailingAddressInd | 0 | false |
| IRS990/OperateHospitalInd | 0 | false |
| IRS990/Organization501c3Ind | 0 | X |
| IRS990/OrganizationFollowsFASB117Ind | 0 | X |
| IRS990/OtherAssetsTotalGrp/BOYAmt | 0 | 8000 |
| IRS990/OtherAssetsTotalGrp/EOYAmt | 0 | 0 |
| IRS990/OtherEmployeeBenefitsGrp/TotalAmt | 0 | 0 |
| IRS990/OtherExpensesGrp/Desc | 0 | OTHER EXPENSES |
| IRS990/OtherExpensesGrp/Desc | 1 | Postage and Shipping |
| IRS990/OtherExpensesGrp/Desc | 2 | BANK CHARGES |
| IRS990/OtherExpensesGrp/ManagementAndGeneralAmt | 0 | 8533 |
| IRS990/OtherExpensesGrp/ManagementAndGeneralAmt | 1 | 10685 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 0 | 23850 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 1 | 21590 |
| IRS990/OtherExpensesGrp/TotalAmt | 0 | 32383 |
| IRS990/OtherExpensesGrp/TotalAmt | 1 | 21590 |
| IRS990/OtherExpensesGrp/TotalAmt | 2 | 10685 |
| IRS990/OtherRevenueMiscGrp/Desc | 0 | OTHER REVENUE |
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| IRS990/OtherRevenueMiscGrp/TotalRevenueColumnAmt | 0 | 5235 |
| IRS990/OtherRevenueTotalAmt | 0 | 5235 |
| IRS990/OtherSalariesAndWagesGrp/TotalAmt | 0 | 0 |
| IRS990/OthNotesLoansReceivableNetGrp/EOYAmt | 0 | 0 |
| IRS990/OwnWebsiteInd | 0 | X |
| IRS990/PartialLiquidationInd | 0 | false |
| IRS990/PaymentsToAffiliatesGrp/TotalAmt | 0 | 0 |
| IRS990/PayPremiumsPrsnlBnftCntrctInd | 0 | false |
| IRS990/PayrollTaxesGrp/ProgramServicesAmt | 0 | 15397 |
| IRS990/PayrollTaxesGrp/TotalAmt | 0 | 15397 |
| IRS990/PensionPlanContributionsGrp/TotalAmt | 0 | 0 |
| IRS990/PledgesAndGrantsReceivableGrp/BOYAmt | 0 | 223020 |
| IRS990/PledgesAndGrantsReceivableGrp/EOYAmt | 0 | 100000 |
| IRS990/PoliticalCampaignActyInd | 0 | false |
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| IRS990/ProfessionalFundraisingInd | 0 | false |
| IRS990/ProhibitedTaxShelterTransInd | 0 | false |
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| IRS990/PYExcessBenefitTransInd | 0 | false |
| IRS990/PYGrantsAndSimilarPaidAmt | 0 | 1394890 |
| IRS990/PYInvestmentIncomeAmt | 0 | 313007 |
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| IRS990/PYOtherRevenueAmt | 0 | 6888 |
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| IRS990/PYTotalExpensesAmt | 0 | 2087691 |
| IRS990/PYTotalRevenueAmt | 0 | 983511 |
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| IRS990/ReceivablesFromOfficersEtcGrp/EOYAmt | 0 | 0 |
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| IRS990/RegularMonitoringEnfrcInd | 0 | true |
| IRS990/RelatedEntityInd | 0 | false |
| IRS990/RelatedOrganizationCtrlEntInd | 0 | false |
| IRS990/ReportInvestmentsOtherSecInd | 0 | true |
| IRS990/ReportLandBuildingEquipmentInd | 0 | false |
| IRS990/ReportOtherAssetsInd | 0 | false |
| IRS990/ReportOtherLiabilitiesInd | 0 | false |
| IRS990/ReportProgramRelatedInvstInd | 0 | false |
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| IRS990/RoyaltiesRevenueGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/SavingsAndTempCashInvstGrp/EOYAmt | 0 | 0 |
| IRS990ScheduleA/First5Years170Ind | 0 | X |
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| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus1YearAmt | 0 | 663616 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 2414743 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus3YearsAmt | 0 | 840696 |
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| IRS990ScheduleA/OtherIncome170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 50325 |
| IRS990ScheduleA/OtherIncome170Grp/TotalAmt | 0 | 62448 |
| IRS990ScheduleA/PublicOrganization170Ind | 0 | X |
| IRS990ScheduleA/PublicSupportCY170Pct | 0 | 0.00000 |
| IRS990ScheduleA/PublicSupportTotal170Amt | 0 | 4865518 |
| IRS990ScheduleA/SubstantialContributorsTotAmt | 0 | 0 |
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| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearAmt | 0 | 946463 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus1YearAmt | 0 | 663616 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 2414743 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus3YearsAmt | 0 | 840696 |
| IRS990ScheduleA/TotalCalendarYear170Grp/TotalAmt | 0 | 4865518 |
| IRS990ScheduleA/TotalSupportAmt | 0 | 5398215 |
| IRS990ScheduleA/UnrelatedBusinessNetIncm170Grp/TotalAmt | 0 | 0 |
| IRS990ScheduleB/ContributorInformationGrp/ContributorBusinessName/BusinessNameLine1 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorNum | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine1 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine2 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/City | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/State | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/ZIPCode | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/TotalContributionsAmt | 0 | RESTRICTED |
| IRS990/ScheduleBRequiredInd | 0 | true |
| IRS990ScheduleD/ExpensesSubtotalAmt | 0 | 2097172 |
| IRS990ScheduleD/FootnoteTextInd | 0 | X |
| IRS990ScheduleD/NetUnrealizedGainsInvstAmt | 0 | -59648 |
| IRS990ScheduleD/RevenueNotReportedAmt | 0 | -59648 |
| IRS990ScheduleD/RevenueSubtotalAmt | 0 | 1297847 |
| IRS990ScheduleD/SupplementalInformationDetail/ExplanationTxt | 0 | THE FOUNDATION DOES NOT BELIEVE ITS FINANCIAL STATEMENTS INCLUDE ANY MATERIAL, UNCERTAIN TAX POSITIONS. TAX FILINGS FOR THE PERIOD ENDED DECEMBER 31, 2021, THE FOUNDATION'S INITIAL FILING, AND LATER ARE SUBJECT TO EXAMINATION BY APPLICABLE TAXING AUTHORITIES. |
| IRS990ScheduleD/SupplementalInformationDetail/FormAndLineReferenceDesc | 0 | Part X : FIN48 Footnote |
| IRS990ScheduleD/TotalBookValueSecuritiesAmt | 0 | 925246 |
| IRS990ScheduleD/TotalExpensesPerForm990Amt | 0 | 2097172 |
| IRS990ScheduleD/TotalRevenuePerForm990Amt | 0 | 1297847 |
| IRS990ScheduleD/TotalRevEtcAuditedFinclStmtAmt | 0 | 1238199 |
| IRS990ScheduleD/TotExpnsEtcAuditedFinclStmtAmt | 0 | 2097172 |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/EmployeeCnt | 0 | 0 |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/OfficesCnt | 0 | 0 |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/RegionTotalExpendituresAmt | 0 | 660854 |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/RegionTxt | 0 | EUROPE |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/SpecificServicesProvidedTxt | 0 | RESEARCH GRANT |
| IRS990ScheduleF/AccountActivitiesOutsideUSGrp/TypeOfActivitiesConductedTxt | 0 | RESEARCH GRANT |
| IRS990ScheduleF/BoycottCountriesInd | 0 | false |
| IRS990ScheduleF/ForeignCorpOwnershipInd | 0 | false |
| IRS990ScheduleF/ForeignPartnershipInd | 0 | false |
| IRS990ScheduleF/InterestInForeignTrustInd | 0 | false |
| IRS990ScheduleF/PassiveForeignInvestmestCoInd | 0 | false |
| IRS990ScheduleF/SubtotalSpentAmt | 0 | 660854 |
| IRS990ScheduleF/TotalSpentAmt | 0 | 660854 |
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