Civic Intelligence

Consortium for Top-Down Proteomics

EIN 83-3404154 • 501(c)3 • Cambridge, MA

Profile

Our Mission is to promote collaboration, education, and innovative research that will accelerate the comprehensive analysis of all human proteoforms. This progress will speed developments in the fields of diagnostics, therapeutics, environment, and energy through the detailed, accurate knowledge of proteoforms and their complexes.

245 First Street Suite 1800Cambridge, MA 02142

www.topdownproteomics.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

59th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2024

Liabilities / Revenue

61st percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2024

Net Margin

24th percentile

-18%

Higher net margin than 24% of similar nonprofits.

501(c)3 • <$500k nonprofits • Source year 2024

Top Officer Pay

95th percentile

$36,000

Higher top officer pay than 95% of similar nonprofits.

Top officer pay equals 105.9% of source-year revenue.

501(c)3 • <$500k nonprofits • Source year 2024

Asset Growth

11th percentile

-84%

Faster asset growth than 11% of similar nonprofits.

501(c)3 • <$500k nonprofits • Annualized from 2023 to 2024

Revenue Growth

18th percentile

-47%

Faster revenue growth than 18% of similar nonprofits.

501(c)3 • <$500k nonprofits • Annualized from 2023 to 2024

Assets

Down

$1,172

Down $6,274 (-84%) from 2023

Liabilities

Flat

$0

Flat from 2023

Net Assets

Down

$1,172

Down $6,274 (-84%) from 2023

Revenue

Down

$34,005

Down $30,062 (-47%) from 2023

Expenses

Down

$40,280

Down $19,818 (-33%) from 2023

Net Income

Down

-$6,275

Down $10,244 (-258%) from 2023

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$8.0K$6.0K$4.0K$2.0K$0Assets 2019: $1,941Liabilities 2019: $02019Assets 2020: $4,890Liabilities 2020: $02020Assets 2021: $2,355Liabilities 2021: $0Net Assets 2021: $2,3552021Assets 2022: $3,477Liabilities 2022: $0Net Assets 2022: $3,4772022Assets 2023: $7,446Liabilities 2023: $0Net Assets 2023: $7,4462023Assets 2024: $1,172Liabilities 2024: $0Net Assets 2024: $1,1722024

Highlighted filing

2024

Assets$1,172
Liabilities$0
Net Assets$1,172

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$80K$60K$40K$20K$0-$20KRevenue 2019: $30,079Expenses 2019: $28,138Net Income 2019: $1,9412019Revenue 2020: $23,008Expenses 2020: $20,059Net Income 2020: $2,9492020Revenue 2021: $36,022Expenses 2021: $38,557Net Income 2021: -$2,5352021Revenue 2022: $37,006Expenses 2022: $35,885Net Income 2022: $1,1212022Revenue 2023: $64,067Expenses 2023: $60,098Net Income 2023: $3,9692023Revenue 2024: $34,005Expenses 2024: $40,280Net Income 2024: -$6,2752024

Highlighted filing

2024

Revenue$34,005
Expenses$40,280
Net Income-$6,275

Filings

Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
May 13, 2025
Return Version
2024v5.0
Gross Receipts
$34,005
Mission and Program Overview

Mission

Our Mission is to promote collaboration, education, and innovative research that will accelerate the comprehensive analysis of all human proteoforms. This progress will speed developments in the fields of diagnostics, therapeutics, environment, and energy through the detailed, accurate knowledge of proteoforms and their complexes.

Program Services

DescriptionGrantsExpenses
We delivered the monthly seminar series titled Proteoform Thursdays which highlight younger researchers in this arena. Over 800 people from 50 countries have attended these events which have covered a range of topics including cancer, antibodies, clinical testing, and plant cell biology.$0$9,264
The Human Proteoform Project. We proposed this ambitious initiative to define the human proteome, that is, to generate a definitive reference set of the proteoforms produced from the genome. This is the critical next step in the quest to understand human health and disease. The program has built relationships and gathered support from important members of the research community.$0$8,056
We planned the 3rd International Symposium on Top-Down Proteomics in Hamburg, Germany August 26-28, 2025. The Symposium will be attended by over 150 scientific leaders who are developing innovative technologies and methods that are transforming our understanding of human biology, ushering in the era of proteoform systems biology & medicine, and paving the way for the Human Proteoform Project.$0$2,861
Compensation and Service Providers

Employees

NameTitleFull / Part TimeBaseOtherTotal
Paul DanisCEO, DirectorPT$36,000-$36,000
Neil KelleherPresident, Director-$0--
Lloyd SmithTreasurer, Director-$0--
Ying GeSecretary, Director-$0--
Jeff AgarDirector-$0--
Julia Chamot-RookeDirector-$0--
Joe LooDirector-$0--
Ljiljana PasaTolicDirector-$0--
Hartmut SchlueterDirector-$0--
Maria MartinDirector-$0--
Filing and Contact Details

Filer

Filer Name
Consortium for Top-down Proteomics
EIN
83-3404154
Phone
6173363280
Address
245 First Street Suite 1800, Cambridge, MA 02142

Signing Officer

Name
Paul Danis
Title
CEO
Phone
6173363280
Signed
2025-05-13
Supplemental Narrative

Additional Explanations

Form 990-EZ, Part I, Line 16

Communications/marketing $1,378; Internet $1,002; Filing fees $36

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