Civic Intelligence

Global Coalition for Adaptive Research

EIN 82-1199380 • 501(c)3 • Larkspur, CA

Profile

Our mission is to lead the development and ongoing management of clinical trial platforms to accelerate the discovery and development of cures for patients with rare and deadly diseases.

700 Larkspur Landing Circle 199Larkspur, CA 94939-1754

gcaresearch.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

63rd percentile

0.38x

Higher debt load relative to assets than 63% of similar nonprofits.

501(c)3 • $50M-$100M nonprofits • Source year 2024

Liabilities / Revenue

73rd percentile

0.88x

Higher debt load relative to revenue than 73% of similar nonprofits.

501(c)3 • $50M-$100M nonprofits • Source year 2024

Net Margin

14th percentile

-12%

Higher net margin than 14% of similar nonprofits.

501(c)3 • $50M-$100M nonprofits • Source year 2024

Top Officer Pay

87th percentile

$1,004,529

Higher top officer pay than 87% of similar nonprofits.

Top officer pay equals 3.6% of source-year revenue.

501(c)3 • $50M-$100M nonprofits • Source year 2024

Asset Growth

53rd percentile

6.7%

Faster asset growth than 53% of similar nonprofits.

501(c)3 • $50M-$100M nonprofits • Annualized from 2023 to 2024

Revenue Growth

22nd percentile

-3.8%

Faster revenue growth than 22% of similar nonprofits.

501(c)3 • $50M-$100M nonprofits • Annualized from 2023 to 2024

Balance Sheet
Liabilities / Assets63rd percentile

Assets

Up

$63,602,270

Up $3,991,540 (+6.7%) from 2023

Liabilities

Up

$24,355,112

Up $4,737,652 (+24%) from 2023

Net Assets

Down

$39,247,158

Down $746,112 (-1.9%) from 2023

Operations
Liabilities / Revenue73rd percentileNet Margin14th percentile

Revenue

Down

$27,688,488

Down $1,090,672 (-3.8%) from 2023

Expenses

Up

$30,895,157

Up $1,184,530 (+4.0%) from 2023

Net Income

Down

-$3,206,669

Down $2,275,202 (-244%) from 2023

Trend Graphs

Balance Sheet Trend

Asset Growth53rd percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$80M$60M$40M$20M$0-$20MAssets 2017: $44,119Liabilities 2017: $300,000Net Assets 2017: -$105,8812017Assets 2018: $109,128Liabilities 2018: $157,655Net Assets 2018: -$48,5272018Assets 2019: $7,395,124Liabilities 2019: $755,402Net Assets 2019: $6,639,7222019Assets 2020: $28,309,589Liabilities 2020: $23,032,332Net Assets 2020: $5,277,2572020Assets 2021: $40,740,875Liabilities 2021: $13,880,420Net Assets 2021: $26,860,4552021Assets 2022: $59,575,227Liabilities 2022: $21,752,254Net Assets 2022: $37,822,9732022Assets 2023: $59,610,730Liabilities 2023: $19,617,460Net Assets 2023: $39,993,2702023Assets 2024: $63,602,270Liabilities 2024: $24,355,112Net Assets 2024: $39,247,1582024

Highlighted filing

2024

Assets$63,602,270
Liabilities$24,355,112
Net Assets$39,247,158
Open 2024 Filing

Operations Trend

Revenue Growth22nd percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$40M$20M$0-$20MRevenue 2017: $0Expenses 2017: $105,881Net Income 2017: -$105,8812017Revenue 2018: $2,525,750Expenses 2018: $2,468,396Net Income 2018: $57,3542018Revenue 2019: $11,915,160Expenses 2019: $5,226,911Net Income 2019: $6,688,2492019Revenue 2020: $15,863,066Expenses 2020: $10,452,245Net Income 2020: $5,410,8212020Revenue 2021: $38,719,697Expenses 2021: $19,203,165Net Income 2021: $19,516,5322021Revenue 2022: $35,373,148Expenses 2022: $24,083,323Net Income 2022: $11,289,8252022Revenue 2023: $28,779,160Expenses 2023: $29,710,627Net Income 2023: -$931,4672023Revenue 2024: $27,688,488Expenses 2024: $30,895,157Net Income 2024: -$3,206,6692024

Highlighted filing

2024

Revenue$27,688,488
Expenses$30,895,157
Net Income-$3,206,669
Open 2024 Filing

Filings

Most recent year

2024 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$63,602,270
Liabilities
$24,355,112
Net assets
$39,247,158
Revenue
$27,688,488
Expenses
$30,895,157
Net income
-$3,206,669
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$63.6$24.4$39.2$27.7$30.9$3.21
2023Detailed filing. Detailed filing data is available for this year.$59.6$19.6$40.0$28.8$29.7$0.93
2022Detailed filing. Detailed filing data is available for this year.$59.6$21.8$37.8$35.4$24.1$11.3
2021Detailed filing. Detailed filing data is available for this year.$40.7$13.9$26.9$38.7$19.2$19.5
2020Detailed filing. Detailed filing data is available for this year.$28.3$23.0$5.28$15.9$10.5$5.41
2019Detailed filing. Detailed filing data is available for this year.$7.40$0.76$6.64$11.9$5.23$6.69
2018Detailed filing. Detailed filing data is available for this year.$0.11$0.16$0.05$2.53$2.47$0.06
2017Detailed filing. Detailed filing data is available for this year.$0.04$0.30$0.11$0.00$0.11$0.11
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
May 13, 2025
Return Version
2024v5.1
Gross Receipts
$46,057,995
Mission and Program Overview

Mission

Our mission is to lead the development and ongoing management of clinical trial platforms to accelerate the discovery and development of cures for patients with rare and deadly diseases.

To lead the development and ongoing management of clinical trial platforms to accelerate the discovery and development of treatments for patients with rare and deadly diseases.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$40,029,401$37,399,235▼ $2,630,166
Investments Other Securities$8,859,855$12,416,075▲ $3,556,220
Accounts Receivable$2,040,738$4,705,822▲ $2,665,084
Savings and Temporary Cash Investments$1,546,512$3,948,737▲ $2,402,225
Prepaid Expenses and Deferred Charges$2,848,349$3,555,673▲ $707,324
Cash and Non-Interest-Bearing Accounts$3,206,238$874,264▼ $2,331,974
Pledges and Grants Receivable$1,079,637$702,464▼ $377,173
Total Assets$59,610,730$63,602,270▲ $3,991,540
Liabilities
Deferred Revenue$11,938,542$18,132,292▲ $6,193,750
Accounts Payable and Accrued Expenses$6,428,918$5,722,820▼ $706,098
Other Liabilities$1,250,000$500,000▼ $750,000
Total Liabilities$19,617,460$24,355,112▲ $4,737,652
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$39,993,270$39,247,158▼ $746,112
Total Net Assets Fund Balance$39,993,270$39,247,158▼ $746,112
Total Liabilities and Net Assets / Fund Balance$59,610,730$63,602,270▲ $3,991,540

Asset Categories

AssetBook ValueDepreciationBasis
Other Securities$12,416,075--
Compensation and Service Providers
Top Officer Pay87th percentile

Employees

NameTitleFull / Part TimeBaseOtherTotal
Meredith BuxtonChief Executive Officer/presidentFT$581,800$422,729$1,004,529
Robert MurrayChief Business and Strategy OfficerFT$359,076$190,833$549,909
Rachael ColemanCFO/COO/treasurerFT$349,999$185,826$535,825
Ashley PowellVice President, Trial OperationsFT$285,000$171,468$456,468
Matthew VivaDirector, Legal/secretaryFT$201,672$85,190$286,862
Tracey RobertsDirector, Trial OperationsFT$210,000$66,426$276,426
Sarah UntchDirector, Trial OperationsFT$201,507$67,109$268,616
Rachel Rosenstein SissonSr Dir, Communications/learning and DevelopmentFT$196,700$20,273$216,973
Rachel Rosenstein SissonSr Dir, Communications/learning and-$166,950$50,023$216,973
Heather KlingSenior Clinical ScientistFT$166,827$48,605$215,432
Naween TamjidiSr. Mgr,trial OperationsFT$164,983$47,975$212,958
Gary Gordon Md PhdSenior Medical Advisor and DirectorPT$165,000-$165,000
Timothy Cloughesy MdChief Medical Officer and DirectorPT$165,000-$165,000
Wk Alfred Yung MdInvestigator International Chair & Director-$26,628-$26,628

Board Members and Trustees

NameTitle
Faramarz Yousefzadeh Jd LlmChairman of the Board
Brian Alexander Md MphDirector
John Frishkopf MmsDirector
Sujuan Ba PhdDirector
Webster Cavenee PhdDirector

Highest Paid Contractors

ContractorServicesLocationCompensation
IqviaCro Services1700 PERIMETER PARK DR, Morrisville, NC 27560$15,877,603
MedidataData Services350 HUDSON ST 9TH FLOOR, New York, NY 10014$457,758
Berry Consultants LLCStatistical Consultation3345 BEE CAVES RD STE 201, Austin, TX 78746$260,000
VoiantClinical Research1171 S ROBERTSON BLVD PMB 414, Los Angeles, CA 90035$210,634
Revenue and Support

Revenue Composition

Contributions and Grants
$1,668,304
Program Service Revenue
$24,168,345
Investment Income
$1,851,839
Other Revenue
$0
All Other Contributions
$1,668,304
Change in Net Assets
$-3,206,669

Audited Revenue Reconciliation

Revenue per Audited Statements
$27,688,488
Revenue Not Reported on Financial Statements
$0
Revenue Not Reported on Form 990
$2,438,403
Total Revenue per Audited Statements
$30,126,891
Total Revenue per Form 990
$27,688,488
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$23,254,301
Salaries, Compensation, and Employee Benefits$7,624,837
Grants and Similar Amounts Paid$16,019
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Fees for Services Other$21,195,588$1,832-$21,197,420
Other Salaries and Wages$2,597,563$1,022,855-$3,620,418
Current Officers, Directors, Trustees, and Key Employees$2,265,885$924,336-$3,190,221
Other Expenses-$1,224,000-$1,224,000
Payroll Taxes$249,834$101,916-$351,750
Other Employee Benefits$239,065$97,523-$336,588
Travel$78,633$216,935-$295,568
Insurance$17,620$123,820-$141,440
Pension Plan Contributions$89,393$36,467-$125,860
Information Technology$11,043$98,905-$109,948
Fees for Service Investment Mgmnt Fees-$66,764-$66,764
Conferences and Meetings$3,422$50,525-$53,947
Fees for Services Accounting-$53,804-$53,804
Office Expenses$7,203$38,119-$45,322
Fees for Services Legal$29,253$15,569-$44,822
Grants to Domestic Orgs$16,019--$16,019
Occupancy-$12,927-$12,927
Advertising-$8,339-$8,339
Total Functional Expenses$26,800,521$4,094,636$0$30,895,157

Audited Expense Reconciliation

Line ItemAmount
Total Expenses per Form 990$30,895,157
Total Expenses per Audited Statements$30,873,003
Expenses per Audited Statements$30,828,393
Expenses Not Reported on Financial Statements$66,764
Expenses Not Reported on Form 990$44,610
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
National Brain Tumor SocietyNewton, MA501(c)(3)Gbm Awareness Day and Walk Sponsorship$10,000
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Refundable Advance$500,000
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section B, Line 11B

“Cfo will review with accounting firm. Once near final will review with ceo. When form is final, form is reviewed with the entire board.”

Form 990, Part VI, Section B, Line 12C

“Each director and officer is required to submit an updated conflict of interest statement on an annual basis. To the extent that relationships are identified via these statements and other information, the individual's constituent record in the company database is updated to include this information, facilitating periodic queries, as necessary. Any board member with a conflict must identify the conflict at any board meeting where the conflict is relevant. The member cannot be present at any part of the meeting where the relevant topic is discussed or voted on. The member cannot be counted for a quorum.”

Form 990, Part VI, Section B, Line 15

“The compensation committee and board of directors are responsible for the review and approval of top level executive management compensation annually. Independent professional experts are called upon for higher level positions and assist in establishing executive salaries in the competitive marketplace. Salaries in both for profit and not for profit organizations are evaluated with the intent on ensuring that the executive compensation program falls within a reasonable range of competitive practices for comparable positions among similarly situated organizations. The review includes incentive plans and all fringe benefits as well as base salary arrangements.”

Form 990, Part VI, Section C, Line 19

“The organization makes its governing documents, conflict of interest policy, and financial statements available to the public upon request.”

Filing and Contact Details

Filer

Filer Name
Global Coalition for Adaptive Research
EIN
82-1199380
Phone
4154948020
Address
700 LARKSPUR LANDING CIRCLE 199, LARKSPUR, CA 94939-1754

Signing Officer

Name
Rachael Coleman
Title
CFO/COO
Phone
4154948020
Signed
2025-05-13
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Meredith Buxton
Formed
2017
Legal Domicile
Md
Voting Board Members
8
Independent Board Members
5
Employees
39
Volunteers
5

Preparer

Firm
Wegner Cpas Llp
Address
419 N LEE ST, ALEXANDRIA, VA 22314-2301
Preparer
Glenn Miller CPA
Phone
7035190990
Supplemental Narrative

Additional Explanations

Form 990, Part III, Line 3

“Activ-4, a small federally funded program supporting covid-19 research concluded its wind-down phase and officially ended in june 2024”

Form 990, Part IX, Line 11G

“Trial expenses: program service expenses 21,195,588. Management and general expenses 0. Fundraising expenses 0. Total expenses 21,195,588. 401k management: program service expenses 0. Management and general expenses 1,832. Fundraising expenses 0. Total expenses 1,832.”

Financial Statement Notes

PART XI, LINE 2D - OTHER ADJUSTMENTS:

“INVESTMENT FEES -66,764.”

Raw XML AppendixShowing 400 of 752 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Form990PartVIISectionAGrp/PersonNm4BRIAN ALEXANDER MD MPH
IRS990/Form990PartVIISectionAGrp/PersonNm5FARAMARZ YOUSEFZADEH JD LLM
IRS990/Form990PartVIISectionAGrp/PersonNm6JOHN FRISHKOPF MMS
IRS990/Form990PartVIISectionAGrp/PersonNm7WEBSTER CAVENEE PHD
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IRS990/Form990PartVIISectionAGrp/PersonNm9MEREDITH BUXTON
IRS990/Form990PartVIISectionAGrp/PersonNm10RACHAEL COLEMAN
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IRS990/Form990PartVIISectionAGrp/PersonNm13RACHEL ROSENSTEIN SISSON
IRS990/Form990PartVIISectionAGrp/PersonNm14SARAH UNTCH
IRS990/Form990PartVIISectionAGrp/PersonNm15TRACEY ROBERTS
IRS990/Form990PartVIISectionAGrp/PersonNm16HEATHER KLING
IRS990/Form990PartVIISectionAGrp/PersonNm17NAWEEN TAMJIDI
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IRS990/Form990PartVIISectionAGrp/TitleTxt0SENIOR MEDICAL ADVISOR AND DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt1CHIEF MEDICAL OFFICER AND DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt2INVESTIGATOR INTERNATIONAL CHAIR & DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt3DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt4DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt5CHAIRMAN OF THE BOARD
IRS990/Form990PartVIISectionAGrp/TitleTxt6DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt7DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt8DIRECTOR, LEGAL/SECRETARY
IRS990/Form990PartVIISectionAGrp/TitleTxt9CHIEF EXECUTIVE OFFICER/PRESIDENT
IRS990/Form990PartVIISectionAGrp/TitleTxt10CFO/COO/TREASURER
IRS990/Form990PartVIISectionAGrp/TitleTxt11VICE PRESIDENT, TRIAL OPERATIONS
IRS990/Form990PartVIISectionAGrp/TitleTxt12CHIEF BUSINESS AND STRATEGY OFFICER
IRS990/Form990PartVIISectionAGrp/TitleTxt13SR DIR, COMMUNICATIONS/LEARNING AND DEVELOPMENT
IRS990/Form990PartVIISectionAGrp/TitleTxt14DIRECTOR, TRIAL OPERATIONS
IRS990/Form990PartVIISectionAGrp/TitleTxt15DIRECTOR, TRIAL OPERATIONS
IRS990/Form990PartVIISectionAGrp/TitleTxt16SENIOR CLINICAL SCIENTIST
IRS990/Form990PartVIISectionAGrp/TitleTxt17SR. MGR,TRIAL OPERATIONS
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IRS990/MissionDesc0OUR MISSION IS TO LEAD THE DEVELOPMENT AND ONGOING MANAGEMENT OF CLINICAL TRIAL PLATFORMS TO ACCELERATE THE DISCOVERY AND DEVELOPMENT OF TREATMENTS FOR PATIENTS WITH RARE AND DEADLY DISEASES.
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IRS990/ProgSrvcAccomActy2Grp/Desc0PROGRAMS IN DEVELOPMENT. ADDITIONAL EFFORTS ARE DEDICATED TO SUPPORTING THE LAUNCH, DESIGN, EDUCATION, OUTREACH, AND CLINICAL COMMUNITY ENGAGEMENT FOR MULTIPLE PROGRAMS CURRENTLY IN DEVELOPMENT, INCLUDING THOSE FOCUSED ON PANCREATIC CANCER, OVARIAN CANCER, AND PTSD. THESE ARE ALL RARE AND/OR LIFE-THREATENING CONDITIONS WITH AN URGENT NEED FOR INNOVATIVE TREATMENT OPTIONS.ONE SMALLER FEDERALLY FUNDED PROGRAM SUPPORTING COVID-19 RESEARCH CONCLUDED ITS WIND-DOWN PHASE AND OFFICIALLY ENDED IN JUNE 2024.
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