Civic Intelligence

Institute for Protein Innovation Inc

EIN 81-3250208 • 501(c)3 • Boston, MA

Profile

The institute for protein innovation is advancing protein science to accelerate research and improve human health.

4 Blackfan Circle 921Boston, MA 02115

proteininnovation.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

16th percentile

0.03x

Higher debt load relative to assets than 16% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2025

Liabilities / Revenue

66th percentile

0.72x

Higher debt load relative to revenue than 66% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2025

Net Margin

1st percentile

-134%

Higher net margin than 1% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Source year 2025

Top Officer Pay

73rd percentile

$809,046

Higher top officer pay than 73% of similar nonprofits.

Top officer pay equals 10.8% of source-year revenue.

501(c)3 • $100M-$250M nonprofits • Source year 2025

Asset Growth

29th percentile

1.3%

Faster asset growth than 29% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2024 to 2025

Revenue Growth

89th percentile

61%

Faster revenue growth than 89% of similar nonprofits.

501(c)3 • $100M-$250M nonprofits • Annualized from 2024 to 2025

Assets

Up

$204,496,998

Up $2,597,524 (+1.3%) from 2024

Liabilities

Up

$5,373,958

Up $1,088,095 (+25%) from 2024

Net Assets

Up

$199,123,040

Up $1,509,429 (+0.8%) from 2024

Revenue

Up

$7,481,529

Up $2,833,600 (+61%) from 2024

Expenses

Up

$17,537,203

Up $2,934,835 (+20%) from 2024

Net Income

Down

-$10,055,674

Down $101,235 (-1.0%) from 2024

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$300M$200M$100M$0Assets 2017: $9,755,889Liabilities 2017: $191,882Net Assets 2017: $9,564,0072017Assets 2018: $15,361,567Liabilities 2018: $1,415,179Net Assets 2018: $13,946,3882018Assets 2019: $9,234,111Liabilities 2019: $782,545Net Assets 2019: $8,451,5662019Assets 2020: $26,558,611Liabilities 2020: $1,009,130Net Assets 2020: $25,549,4812020Assets 2021: $219,080,402Liabilities 2021: $1,107,147Net Assets 2021: $217,973,2552021Assets 2022: $191,011,980Liabilities 2022: $1,081,048Net Assets 2022: $189,930,9322022Assets 2023: $196,826,153Liabilities 2023: $5,622,463Net Assets 2023: $191,203,6902023Assets 2024: $201,899,474Liabilities 2024: $4,285,863Net Assets 2024: $197,613,6112024Assets 2025: $204,496,998Liabilities 2025: $5,373,958Net Assets 2025: $199,123,0402025

Highlighted filing

2025

Assets$204,496,998
Liabilities$5,373,958
Net Assets$199,123,040

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$300M$200M$100M$0-$100MRevenue 2017: $10,096,202Expenses 2017: $532,195Net Income 2017: $9,564,0072017Revenue 2018: $8,755,283Expenses 2018: $3,855,437Net Income 2018: $4,899,8462018Revenue 2019: $1,521,195Expenses 2019: $7,094,240Net Income 2019: -$5,573,0452019Revenue 2020: $24,674,930Expenses 2020: $7,577,015Net Income 2020: $17,097,9152020Revenue 2021: $200,786,087Expenses 2021: $9,301,960Net Income 2021: $191,484,1272021Revenue 2022: $5,178,433Expenses 2022: $10,986,031Net Income 2022: -$5,807,5982022Revenue 2023: $4,022,792Expenses 2023: $13,197,650Net Income 2023: -$9,174,8582023Revenue 2024: $4,647,929Expenses 2024: $14,602,368Net Income 2024: -$9,954,4392024Revenue 2025: $7,481,529Expenses 2025: $17,537,203Net Income 2025: -$10,055,6742025

Highlighted filing

2025

Revenue$7,481,529
Expenses$17,537,203
Net Income-$10,055,674

Filings

Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jul 1, 2024 to Jun 30, 2025
Signed
Nov 21, 2025
Return Version
2024v5.2
Gross Receipts
$74,209,892
Mission and Program Overview

Mission

The institute for protein innovation is advancing protein science to accelerate research and improve human health.

To advance protein science to accelerate research and improve human health.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$188,859,805$185,747,029▼ $3,112,776
Investments Other Securities$3,323,493$5,957,988▲ $2,634,495
Land, Buildings, and Equipment, Net$3,500,502$5,136,340▲ $1,635,838
Savings and Temporary Cash Investments$1,598,098$2,256,250▲ $658,152
Prepaid Expenses and Deferred Charges$678,068$881,861▲ $203,793
Cash and Non-Interest-Bearing Accounts$455,833$262,232▼ $193,601
Pledges and Grants Receivable$18,263$15,194▼ $3,069
Total Assets$201,899,474$204,496,998▲ $2,597,524
Other Assets Total$3,465,412$4,240,104▲ $774,692
Liabilities
Other Liabilities$3,588,265$4,317,218▲ $728,953
Accounts Payable and Accrued Expenses$697,598$1,056,740▲ $359,142
Total Liabilities$4,285,863$5,373,958▲ $1,088,095
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$197,613,611$198,863,481▲ $1,249,870
Net Assets With Donor Restrictions-$259,559-
Total Net Assets Fund Balance$197,613,611$199,123,040▲ $1,509,429
Total Liabilities and Net Assets / Fund Balance$201,899,474$204,496,998▲ $2,597,524

Asset Categories

AssetBook ValueDepreciationBasis
Equipment$5,013,553$4,751,775$9,765,328
Leasehold Improvements$122,787$232,579$355,366
Compensation and Service Providers

Employees

NameTitleFull / Part TimeBaseOtherTotal
Kenneth FasmanPresident & CEO/ex-officioFT$533,793$275,253$809,046
Rob MeijersSenior Director Antibody PlatformFT$271,339$58,989$330,328
Bettina StevensCFO (until 10/24)FT$248,242$45,959$294,201
Trisha GuraDirector of CommunicationsFT$239,660$44,295$283,955
Andre TeixeiraSr. Director of Antibody PlatformFT$238,270$45,072$283,342
Deborah MoshinskyDirector Antibody CharacterizationFT$210,606$69,777$280,383
Curtis WaltonDirector of Laboratory AutomationFT$233,334$44,154$277,488

Board Members and Trustees

NameTitle
Samantha SingerChair
Dr Timothy a SpringerCo-founder/director
Dr Amir NashatDirector
Dr Auro NairDirector
Dr Maykin HoDirector
Dr Rusty WilliamsDirector
Dr Stephen BlacklowDirector
Dr Steven C AlmoDirector
Israel RozenDirector
Dr Jeffrey FlierDirector (until 12/24)
MICHAEL O'HARATreasurer

Highest Paid Contractors

ContractorServicesLocationCompensation
Nelson Mullins Riley & Scarborough LLPLegal ServicesPO BOX 11070, Columbia, SC 29211$204,918
Danforth Advisors LLCAccounting Services300 FIFTH AVE PO BOX 335, Waltham, MA 01772$154,750
Revenue and Support

Revenue Composition

Contributions and Grants
$500,000
Program Service Revenue
$97,790
Investment Income
$6,883,739
Other Revenue
$0
All Other Contributions
$500,000
Change in Net Assets
$-10,055,674

Audited Revenue Reconciliation

Revenue per Audited Statements
$7,148,339
Revenue Not Reported on Financial Statements
$333,190
Revenue Not Reported on Form 990
$11,565,103
Total Revenue per Audited Statements
$18,713,442
Total Revenue per Form 990
$7,481,529
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$8,983,702
Salaries, Compensation, and Employee Benefits$8,553,501
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$4,758,969$1,381,571-$6,140,540
Occupancy$2,027,495$658,936-$2,686,431
Depreciation Depletion$1,002,141$12,331-$1,014,472
Other Employee Benefits$697,539$157,494-$855,033
Current Officers, Directors, Trustees, and Key Employees-$806,940-$806,940
Fees for Services Other$119,905$457,324-$577,229
Payroll Taxes$315,581$115,447-$431,028
Other Expenses$131,282$238,770-$370,052
Fees for Service Investment Mgmnt Fees-$333,190-$333,190
Pension Plan Contributions$259,842$60,118-$319,960
Fees for Services Accounting-$106,751-$106,751
Fees for Services Legal$28,242$11,980-$40,222
Information Technology$1,750$5,995-$7,745
Total Functional Expenses$12,971,110$4,566,093$0$17,537,203

Audited Expense Reconciliation

Line ItemAmount
Total Expenses per Form 990$17,537,203
Expenses per Audited Statements$17,204,013
Total Expenses per Audited Statements$17,204,013
Expenses Not Reported on Financial Statements$333,190
Expenses Not Reported on Form 990$0
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Operating Lease Obligation$4,317,218
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

Timothy springer and amir nashat have a business relationship as defined by the irs. Amir nashat and jeffrey flier also have a business relationship as defined by the irs.

Form 990, Part VI, Section B, Line 11B

The form 990 is prepared by the institute's independent external audit firm based on information provided by management. The finance director, ceo, and controller review the draft form 990 for accuracy. Once any corrections and revisions are made, the form is then provided to the institute's legal counsel and audit and finance committee of the board of directors. The audit and finance committee meets with the external audit firm to review the draft. After approval by the audit and finance committee, the form 990 is submitted to each member of the board of directors for review and approval prior to filing with the irs.

Form 990, Part VI, Section B, Line 12C

The institute has a conflict of interest policy that applies to all officers, directors and key employees. The policy is monitored by the institute's conflict of interest committee and legal counsel. The policy requires each director to submit, on an annual basis, a coi disclosure of any situations that could give rise to the appearance of a conflict of interest for review by legal counsel and the coi committee. Each director has a continuing obligation, under the policy, to disclose any potential conflicts of interest at the time they arise during the course of the year to the coi committee. All submissions are reviewed by legal counsel and the coi committee for a determination and appropriate action.

Form 990, Part VI, Section B, Line 15

Compensation of executive officer(s) and key employees is reviewed and approved by the board of directors. The board of directors are independent of employment of the institute and are guided by the compensation committee of the board of directors. The compensation committee, as described in the committee's charter, is comprised of two or more directors as prescribed by the bylaws, each of whom is independent and free from any relationship that would interfere in their responsibilities as a member of the compensation committee. The committee reviews, on an annual basis, the corporate goals and objectives relevant to the compensation of the ceo and evaluates the ceo's performance considering the goals and objectives. Based on this review and evaluation, the committee then recommends the ceo's compensation to the board for approval. The ceo makes recommendations for key employee compensation for employees in a direct reporting relationship to the ceo with respect to: (a) salary; (b) bonus or other incentive awards; (c) supplemental benefits, including retirement benefits and deferred compensation; (d) employment agreements and severance arrangements; and (e ) prerequisites. The committee reviews and approves the ceo's recommendation as well as provides oversight for the process. As part of the annual budget process, the compensation committee in conjunction with the audit and finance committee reviews and approves annual proposed compensation plans for the coming fiscal year for salary increases and employee benefit plan terms. The board utilizes the radford compensation survey data to determine the appropriate compensation range for positions and engages a compensation consultant with specialized nonprofit practice expertise to assist the committee in reviewing executive officer and key employee compensation, including analysis of comparability data for the board's review.

Form 990, Part VI, Section C, Line 19

The institute's governing documents, conflict of interest policy, and financial statements are available to the public upon request.

Filing and Contact Details

Filer

Filer Name
Institute for Protein Innovation Inc
EIN
81-3250208
Phone
6173147970
Address
4 BLACKFAN CIRCLE 921, BOSTON, MA 02115

Signing Officer

Name
Kenneth Fasman Phd
Title
President & CEO
Phone
6173147970
Signed
2025-11-21
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Kenneth Fasman Phd
Formed
2016
Legal Domicile
Ma
Voting Board Members
11
Independent Board Members
10
Employees
63
Volunteers
33

Preparer

Firm
Aafcpas Inc
Address
50 WASHINGTON STREET, WESTBOROUGH, MA 01581
Preparer
Thomas F Muldoon CPA
Phone
5083669100
Supplemental Narrative

Additional Explanations

FORM 990, PART I, LINE 6:

The institute does not formally track volunteers but has included the number of board of directors and scientific advisory board members that are uncompensated.

FORM 990, PART XII, LINE 2C:

The board of directors is responsible for oversight of the audit process and review of the financial statements.

Financial Statement Notes

PART X, LINE 2:

The institute accounts for uncertainty in income taxes in accordance with asc topic, income taxes. This standard clarifies the accounting for uncertainty in tax positions and prescribes a recognition threshold and measurement attribute for the financial statements regarding a tax position taken or expected to be taken in a tax return. The institute has determined that there are no uncertain tax positions which qualify for either recognition or disclosure in the financial statements at june 30, 2025. The institute's information returns are subject to examination by the federal and state jurisdictions.

Raw XML AppendixShowing 400 of 631 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Form990PartVIISectionAGrp/PersonNm1SAMANTHA SINGER
IRS990/Form990PartVIISectionAGrp/PersonNm2MICHAEL O'HARA
IRS990/Form990PartVIISectionAGrp/PersonNm3DR TIMOTHY A SPRINGER
IRS990/Form990PartVIISectionAGrp/PersonNm4DR STEVEN C ALMO
IRS990/Form990PartVIISectionAGrp/PersonNm5DR MAYKIN HO
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IRS990/Form990PartVIISectionAGrp/PersonNm17CURTIS WALTON
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IRS990/Form990PartVIISectionAGrp/ReportableCompFromRltdOrgAmt160
IRS990/Form990PartVIISectionAGrp/ReportableCompFromRltdOrgAmt170
IRS990/Form990PartVIISectionAGrp/TitleTxt0PRESIDENT & CEO/EX-OFFICIO
IRS990/Form990PartVIISectionAGrp/TitleTxt1CHAIR
IRS990/Form990PartVIISectionAGrp/TitleTxt2TREASURER
IRS990/Form990PartVIISectionAGrp/TitleTxt3CO-FOUNDER/DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt4DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt5DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt6DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt7DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt8DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt9DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt10DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt11DIRECTOR (UNTIL 12/24)
IRS990/Form990PartVIISectionAGrp/TitleTxt12CFO (UNTIL 10/24)
IRS990/Form990PartVIISectionAGrp/TitleTxt13SENIOR DIRECTOR ANTIBODY PLATFORM
IRS990/Form990PartVIISectionAGrp/TitleTxt14DIR. OF COMMUNICATIONS
IRS990/Form990PartVIISectionAGrp/TitleTxt15SR. DIR. OF ANTIBODY PLATFORM
IRS990/Form990PartVIISectionAGrp/TitleTxt16DIRECTOR ANTIBODY CHARACTERIZATION
IRS990/Form990PartVIISectionAGrp/TitleTxt17DIRECTOR OF LABORATORY AUTOMATION
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IRS990/FormationYr02016
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IRS990/FSAuditedInd01
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IRS990/GoverningBodyVotingMembersCnt011
IRS990/GrantsToIndividualsInd00
IRS990/GrantsToOrganizationsInd00
IRS990/GrantToRelatedPersonInd00
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IRS990/InformationTechnologyGrp/ManagementAndGeneralAmt05995
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IRS990/LandBldgEquipCostOrOtherBssAmt010120694
IRS990/LegalDomicileStateCd0MA
IRS990/LessCostOthBasisSalesExpnssGrp/OtherAmt09244
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IRS990/LoanOutstandingInd00
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IRS990/LocalChaptersInd00
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IRS990/MembersOrStockholdersInd00
IRS990/MethodOfAccountingAccrualInd0X
IRS990/MinutesOfCommitteesInd01
IRS990/MinutesOfGoverningBodyInd01
IRS990/MissionDesc0THE INSTITUTE FOR PROTEIN INNOVATION IS ADVANCING PROTEIN SCIENCE TO ACCELERATE RESEARCH AND IMPROVE HUMAN HEALTH.
IRS990/MoreThan5000KToIndividualsInd00
IRS990/MoreThan5000KToOrgInd00
IRS990/NetAssetsOrFundBalancesBOYAmt0197613611
IRS990/NetAssetsOrFundBalancesEOYAmt0199123040
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IRS990/OccupancyGrp/ProgramServicesAmt02027495
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IRS990/OfficerMailingAddressInd00
IRS990/OperateHospitalInd00
IRS990/Organization501c3Ind0X
IRS990/OrganizationFollowsFASB117Ind0X
IRS990/OtherAssetsTotalGrp/BOYAmt03465412
IRS990/OtherAssetsTotalGrp/EOYAmt04240104
IRS990/OtherChangesInNetAssetsAmt00
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IRS990/OtherEmployeeBenefitsGrp/ProgramServicesAmt0697539
IRS990/OtherEmployeeBenefitsGrp/TotalAmt0855033
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IRS990/PledgesAndGrantsReceivableGrp/BOYAmt018263
IRS990/PledgesAndGrantsReceivableGrp/EOYAmt015194
IRS990/PoliticalCampaignActyInd00
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IRS990/PrepaidExpensesDefrdChargesGrp/EOYAmt0881861
IRS990/PrincipalOfficerNm0KENNETH FASMAN PHD
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IRS990/ProgramServiceRevenueGrp/Desc0LICENSING REVENUE
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IRS990/ProgramServiceRevenueGrp/Desc2ANTIBODY SALES
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IRS990/ProgramServiceRevenueGrp/RelatedOrExemptFuncIncomeAmt131467
IRS990/ProgramServiceRevenueGrp/RelatedOrExemptFuncIncomeAmt222725
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IRS990/ProgramServiceRevenueGrp/TotalRevenueColumnAmt131467
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IRS990/PYOtherRevenueAmt00
IRS990/PYProgramServiceRevenueAmt042841
IRS990/PYRevenuesLessExpensesAmt0-9954439
IRS990/PYSalariesCompEmpBnftPaidAmt07647734
IRS990/PYTotalExpensesAmt014602368
IRS990/PYTotalProfFndrsngExpnsAmt00
IRS990/PYTotalRevenueAmt04647929
IRS990/QuidProQuoContributionsInd00
IRS990/RcvFndsToPayPrsnlBnftCntrctInd00
IRS990/ReconcilationRevenueExpnssAmt0-10055674
IRS990/RegularMonitoringEnfrcInd01
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IRS990/RelatedOrganizationCtrlEntInd00
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IRS990/ReportLandBuildingEquipmentInd01
IRS990/ReportOtherAssetsInd00
IRS990/ReportOtherLiabilitiesInd01
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IRS990/RevenueAmt097790
IRS990/SavingsAndTempCashInvstGrp/BOYAmt01598098
IRS990/SavingsAndTempCashInvstGrp/EOYAmt02256250
IRS990ScheduleA/Form990ScheduleAPartVIGrp/ExplanationTxt0THE INSTITUTE IS A MEDICAL RESEARCH ORGANIZATION FOR ITS TAXABLE YEAR ENDED JUNE 30, 2025, AS ITS MEDICAL RESEARCH PROGRAM EXPENSES OF $12,971,110 FOR THAT YEAR EXCEEDED THE MRO REQUIREMENT OF $6,709,676 (3.5% OF ITS ENDOWMENT).
IRS990ScheduleA/Form990ScheduleAPartVIGrp/FormAndLineReferenceDesc0PART 1, LINE 4:
IRS990ScheduleA/HospitalNameAndAddressGrp/CityNm0BOSTON
IRS990ScheduleA/HospitalNameAndAddressGrp/StateAbbreviationCd0MA
IRS990ScheduleA/HospitalNameAndAddressGrp/SupportedOrganizationName/BusinessNameLine1Txt0BOSTON CHILDREN'S HOSPITAL
IRS990ScheduleA/MedicalResearchOrganizationInd0X
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IRS990ScheduleB/ContributorInformationGrp/ContributorNum0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine10RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine20RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/City0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/State0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/ZIPCode0RESTRICTED
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IRS990/ScheduleBRequiredInd01
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IRS990ScheduleD/EquipmentGrp/DepreciationAmt04751775
IRS990ScheduleD/EquipmentGrp/OtherCostOrOtherBasisAmt09765328
IRS990ScheduleD/ExpensesNotReportedAmt00
IRS990ScheduleD/ExpensesNotRptFinclStmtAmt0333190
IRS990ScheduleD/ExpensesSubtotalAmt017204013
IRS990ScheduleD/FootnoteTextInd0X
IRS990ScheduleD/InvestmentExpensesNotIncld2Amt0333190
IRS990ScheduleD/InvestmentExpensesNotIncldAmt0333190
IRS990ScheduleD/LeaseholdImprovementsGrp/BookValueAmt0122787
IRS990ScheduleD/LeaseholdImprovementsGrp/DepreciationAmt0232579
IRS990ScheduleD/LeaseholdImprovementsGrp/OtherCostOrOtherBasisAmt0355366
IRS990ScheduleD/NetUnrealizedGainsInvstAmt011565103
IRS990ScheduleD/OtherLiabilitiesOrgGrp/Amt04317218
IRS990ScheduleD/OtherLiabilitiesOrgGrp/Desc0OPERATING LEASE OBLIGATION
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IRS990ScheduleD/RevenueNotReportedFinclStmtAmt0333190
IRS990ScheduleD/RevenueSubtotalAmt07148339

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