Civic Intelligence

Human Proteome Organization - Hupo

EIN 80-0814948 • 501(c)3 • Newton, MA

Profile

promote the development and application of proteome technologies to enhance biological knowledge, global health and wellness through international collaboration, coordination, education and advocacy in an inclusive and empowering environment.

1150 Walnut Street 2nd FloorNewton, MA 02461

www.hupo.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

61st percentile

0.14x

Higher debt load relative to assets than 61% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Liabilities / Revenue

84th percentile

0.64x

Higher debt load relative to revenue than 84% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Net Margin

11th percentile

-28%

Higher net margin than 11% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Top Officer Pay

40th percentile

$0

Higher top officer pay than 40% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

501(c)3 • $1M-$5M nonprofits • Source year 2024

Asset Growth

40th percentile

0.3%

Faster asset growth than 40% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Annualized from 2023 to 2024

Revenue Growth

1st percentile

-85%

Faster revenue growth than 1% of similar nonprofits.

501(c)3 • $1M-$5M nonprofits • Annualized from 2023 to 2024

Assets

Up

$1,062,343

Up $3,112 (+0.3%) from 2023

Liabilities

Up

$149,907

Up $68,632 (+84%) from 2023

Net Assets

Down

$912,436

Down $65,520 (-6.7%) from 2023

Revenue

Down

$233,025

Down $1,314,500 (-85%) from 2023

Expenses

Down

$298,545

Down $1,041,600 (-78%) from 2023

Net Income

Down

-$65,520

Down $272,900 (-132%) from 2023

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$1.5M$1.0M$500K$0Assets 2013: $429,279Liabilities 2013: $2,0002013Assets 2014: $484,700Liabilities 2014: $0Net Assets 2014: $484,7002014Assets 2015: $545,908Liabilities 2015: $44,004Net Assets 2015: $501,9042015Assets 2016: $564,459Liabilities 2016: $77,903Net Assets 2016: $486,5562016Assets 2017: $524,266Liabilities 2017: $52,821Net Assets 2017: $471,4452017Assets 2018: $519,959Liabilities 2018: $61,433Net Assets 2018: $458,5262018Assets 2019: $529,195Liabilities 2019: $69,052Net Assets 2019: $460,1432019Assets 2020: $624,533Liabilities 2020: $66,410Net Assets 2020: $558,1232020Assets 2021: $683,130Liabilities 2021: $78,432Net Assets 2021: $604,6982021Assets 2022: $1,100,150Liabilities 2022: $329,574Net Assets 2022: $770,5762022Assets 2023: $1,059,231Liabilities 2023: $81,275Net Assets 2023: $977,9562023Assets 2024: $1,062,343Liabilities 2024: $149,907Net Assets 2024: $912,4362024

Highlighted filing

2024

Assets$1,062,343
Liabilities$149,907
Net Assets$912,436

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$2.0M$1.5M$1.0M$500K$0-$500KRevenue 2013: $68,693Expenses 2013: $180,750Net Income 2013: -$112,0572013Revenue 2014: $222,375Expenses 2014: $164,954Net Income 2014: $57,4212014Revenue 2015: $151,800Expenses 2015: $128,984Net Income 2015: $22,8162015Revenue 2016: $147,695Expenses 2016: $163,043Net Income 2016: -$15,3482016Revenue 2017: $140,125Expenses 2017: $155,236Net Income 2017: -$15,1112017Revenue 2018: $161,027Expenses 2018: $173,946Net Income 2018: -$12,9192018Revenue 2019: $169,013Expenses 2019: $167,396Net Income 2019: $1,6172019Revenue 2020: $340,198Expenses 2020: $242,218Net Income 2020: $97,9802020Revenue 2021: $537,131Expenses 2021: $490,556Net Income 2021: $46,5752021Revenue 2022: $1,065,685Expenses 2022: $899,807Net Income 2022: $165,8782022Revenue 2023: $1,547,525Expenses 2023: $1,340,145Net Income 2023: $207,3802023Revenue 2024: $233,025Expenses 2024: $298,545Net Income 2024: -$65,5202024

Highlighted filing

2024

Revenue$233,025
Expenses$298,545
Net Income-$65,520

Filings

Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jan 1, 2024 to Dec 31, 2024
Signed
Sep 1, 2025
Return Version
2024v5.2
Gross Receipts
$233,025
Mission and Program Overview

Mission

define and promote proteomics through international cooperation and collaboration in fostering the development of new tecnologies, techniques, and training to better understand human disease

promote the development and application of proteome technologies to enhance biological knowledge, global health and wellness through international collaboration, coordination, education and advocacy in an inclusive and empowering environment.

Balance Sheet Detail
LineBeginningEndChange
Assets
Savings and Temporary Cash Investments$251,725$510,766▲ $259,041
Cash and Non-Interest-Bearing Accounts$761,096$358,167▼ $402,929
Accounts Receivable$26,910$103,410▲ $76,500
Prepaid Expenses and Deferred Charges$19,500$90,000▲ $70,500
Other Notes and Loans Receivable, Net-$0-
Pledges and Grants Receivable-$0-
Receivable From Disqualified Prsn-$0-
Receivables From Officers Etc-$0-
Investments Other Securities-$0-
Investments Program Related-$0-
Investments in Publicly Traded Securities-$0-
Land, Buildings, and Equipment, Net-$0-
Intangible Assets-$0-
Inventories for Sale or Use-$0-
Total Assets$1,059,231$1,062,343▲ $3,112
Other Assets Total-$0-
Liabilities
Accounts Payable and Accrued Expenses$73,080$143,002▲ $69,922
Deferred Revenue$8,195$6,905▼ $1,290
Total Liabilities$81,275$149,907▲ $68,632
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$977,956$912,436▼ $65,520
Total Net Assets Fund Balance$977,956$912,436▼ $65,520
Total Liabilities and Net Assets / Fund Balance$1,059,231$1,062,343▲ $3,112
Compensation and Service Providers

Board Members and Trustees

Highest Paid Contractors

ContractorServicesLocationCompensation
Intl Conference Svcs Ltdgenl mgt/annual conf mgt555 Burrard St, Vancouver, BC, Ca$155,819
Revenue and Support

Revenue Composition

Contributions and Grants
$0
Program Service Revenue
$223,365
Investment Income
$9,060
Other Revenue
$600
Change in Net Assets
$-65,520
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$298,545
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Fees for Services Management$95,456$51,400-$146,856
Conferences and Meetings$120,602--$120,602
Information Technology$5,071$2,730-$7,801
Fees for Services Legal-$6,620-$6,620
Fees for Services Accounting-$5,825-$5,825
Other Expenses$5,067--$5,067
Insurance$2,192$1,180-$3,372
Travel$1,244--$1,244
Office Expenses$753$405-$1,158
Total Functional Expenses$230,385$68,160$0$298,545
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Receivables from Disqualified Persons-$0-
Receivables from Officers, Directors, Trustees, and Key Employees-$0-
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
No
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 6

The organization is governed by a board of directors, referred to as the Council, which consists of up to 48 members who serve 3-year staggered terms. The Council meets once a year at the annual congress. The Council has authorized an Executive Committee, consisting of HUPO's 5 officers and 2 at-large members who serve 2-year terms, to confer monthly via conference call and manage HUPO business between congresses.

Form 990, Part VI, Section B, Line 11B

The organization's financial statements and a prepared 990 are forwarded to the Executive Committee for review. After review and approval the Treasurer signs and files the 990.

Form 990, Part VI, Section C, Line 19

Requests for these documents are processed by the organization's mgmt staff. Contact information for the staff is listed on the organization's website.

Form 990, Part VIII, Line 2A - Meeting Income

The income on this line is from a qualified convention/trade show, which is excluded from "unrelated trade or business" income under Section 513(d)(3)

Filing and Contact Details

Filer

Filer Name
Human Proteome Organization - HUPO
EIN
80-0814948
Phone
6045585498
Address
1150 Walnut Street 2nd Floor, Newton, MA 02461

Signing Officer

Name
Bernd Wollscheid
Title
Treasurer
Signed
2025-09-01
Discuss with paid preparer
Yes

Organization Details

Formed
2004
Legal Domicile
Nm
Voting Board Members
57
Independent Board Members
57
Employees
0

Preparer

Firm
Michael J Cavanaugh PA
Address
5603 Oakmont Avenue, Bethesda, MD 20817
Preparer
Michael J Cavanaugh
Phone
3015649350
Supplemental Narrative

Additional Explanations

Form 990, Part IV, line 14B - Program Service Activities Outside USA

The organiztion did not directly conduct any activities outside the U S. However, it did contract with its affiliate in Germany to host the 23rd Human Proteome Organization Congress in Dresden Germany: the resuults from that Congress are included on this return.

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This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990ScheduleA/InvestmentIncomeAndUBTIGrp/CurrentTaxYearMinus3YearsAmt017
IRS990ScheduleA/InvestmentIncomeAndUBTIGrp/CurrentTaxYearMinus4YearsAmt02178
IRS990ScheduleA/InvestmentIncomeAndUBTIGrp/TotalAmt013490
IRS990ScheduleA/InvestmentIncomeCYPct00.00360
IRS990ScheduleA/InvestmentIncomePYPct00.00380
IRS990ScheduleA/NetIncomeFromOtherUBIGrp/TotalAmt00
IRS990ScheduleA/OtherIncome509Grp/CurrentTaxYearAmt0600
IRS990ScheduleA/OtherIncome509Grp/CurrentTaxYearMinus1YearAmt01700
IRS990ScheduleA/OtherIncome509Grp/CurrentTaxYearMinus2YearsAmt0300
IRS990ScheduleA/OtherIncome509Grp/CurrentTaxYearMinus3YearsAmt0450
IRS990ScheduleA/OtherIncome509Grp/CurrentTaxYearMinus4YearsAmt0100
IRS990ScheduleA/OtherIncome509Grp/TotalAmt03150
IRS990ScheduleA/Post1975UBTIGrp/TotalAmt00
IRS990ScheduleA/PubliclySupportedOrg509a2Ind0X
IRS990ScheduleA/PublicSupportCY509Pct00.80760
IRS990ScheduleA/PublicSupportPY509Pct00.80780
IRS990ScheduleA/PublicSupportTotal509Amt03007009
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/CurrentTaxYearAmt016250
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/CurrentTaxYearMinus1YearAmt0358508
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/CurrentTaxYearMinus2YearsAmt0314607
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/CurrentTaxYearMinus3YearsAmt05625
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/CurrentTaxYearMinus4YearsAmt04925
IRS990ScheduleA/SubstAndDsqlfyPrsnsTotGrp/TotalAmt0699915
IRS990ScheduleA/SubstantialContributorsAmtGrp/CurrentTaxYearMinus1YearAmt0344258
IRS990ScheduleA/SubstantialContributorsAmtGrp/CurrentTaxYearMinus2YearsAmt0301282
IRS990ScheduleA/SubstantialContributorsAmtGrp/TotalAmt0645540
IRS990ScheduleA/TaxRevLeviedOrgnztnlBnft509Grp/TotalAmt00
IRS990ScheduleA/ThirtyThrPctSuprtTestsCY509Ind0X
IRS990ScheduleA/Total509Grp/CurrentTaxYearAmt0223365
IRS990ScheduleA/Total509Grp/CurrentTaxYearMinus1YearAmt01543590
IRS990ScheduleA/Total509Grp/CurrentTaxYearMinus2YearsAmt01065385
IRS990ScheduleA/Total509Grp/CurrentTaxYearMinus3YearsAmt0536664
IRS990ScheduleA/Total509Grp/CurrentTaxYearMinus4YearsAmt0337920
IRS990ScheduleA/Total509Grp/TotalAmt03706924
IRS990ScheduleA/TotalSupportCalendarYearGrp/CurrentTaxYearAmt0233025
IRS990ScheduleA/TotalSupportCalendarYearGrp/CurrentTaxYearMinus1YearAmt01547525
IRS990ScheduleA/TotalSupportCalendarYearGrp/CurrentTaxYearMinus2YearsAmt01065685
IRS990ScheduleA/TotalSupportCalendarYearGrp/CurrentTaxYearMinus3YearsAmt0537131
IRS990ScheduleA/TotalSupportCalendarYearGrp/CurrentTaxYearMinus4YearsAmt0340198
IRS990ScheduleA/TotalSupportCalendarYearGrp/TotalAmt03723564
IRS990/ScheduleBRequiredInd0false
IRS990/ScheduleJRequiredInd0false
IRS990/ScheduleORequiredInd0true
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt0The organization is governed by a board of directors, referred to as the Council, which consists of up to 48 members who serve 3-year staggered terms. The Council meets once a year at the annual congress. The Council has authorized an Executive Committee, consisting of HUPO's 5 officers and 2 at-large members who serve 2-year terms, to confer monthly via conference call and manage HUPO business between congresses.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt1The organization's financial statements and a prepared 990 are forwarded to the Executive Committee for review. After review and approval the Treasurer signs and files the 990.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt2Requests for these documents are processed by the organization's mgmt staff. Contact information for the staff is listed on the organization's website.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt3The organiztion did not directly conduct any activities outside the U S. However, it did contract with its affiliate in Germany to host the 23rd Human Proteome Organization Congress in Dresden Germany: the resuults from that Congress are included on this return.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt4The income on this line is from a qualified convention/trade show, which is excluded from "unrelated trade or business" income under Section 513(d)(3)
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc0Form 990, Part VI, Section A, Line 6
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc1Form 990, Part VI, Section B, Line 11b
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc2Form 990, Part VI, Section C, Line 19
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc3Form 990, Part IV, line 14b - Program Service Activities Outside USA
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc4Form 990, Part VIII, Line 2a - Meeting Income
IRS990/SchoolOperatingInd0false
IRS990/SignificantChangeInd0false
IRS990/SignificantNewProgramSrvcInd0false
IRS990/SubjectToExcsTaxNetInvstIncInd0false
IRS990/SubjectToProxyTaxInd0false
IRS990/SubjToTaxRmnrtnExPrchtPymtInd0false
IRS990/TaxablePartyNotificationInd0false
IRS990/TaxExemptBondsInd0false
IRS990/TerminateOperationsInd0false
IRS990/TotalAssetsBOYAmt01059231
IRS990/TotalAssetsEOYAmt01062343
IRS990/TotalAssetsGrp/BOYAmt01059231
IRS990/TotalAssetsGrp/EOYAmt01062343
IRS990/TotalCompGreaterThan150KInd0false
IRS990/TotalContributionsAmt00
IRS990/TotalEmployeeCnt00
IRS990/TotalFunctionalExpensesGrp/FundraisingAmt00
IRS990/TotalFunctionalExpensesGrp/ManagementAndGeneralAmt068160
IRS990/TotalFunctionalExpensesGrp/ProgramServicesAmt0230385
IRS990/TotalFunctionalExpensesGrp/TotalAmt0298545
IRS990/TotalGrossUBIAmt00
IRS990/TotalLiabilitiesBOYAmt081275
IRS990/TotalLiabilitiesEOYAmt0149907
IRS990/TotalLiabilitiesGrp/BOYAmt081275
IRS990/TotalLiabilitiesGrp/EOYAmt0149907
IRS990/TotalNetAssetsFundBalanceGrp/BOYAmt0977956
IRS990/TotalNetAssetsFundBalanceGrp/EOYAmt0912436
IRS990/TotalProgramServiceExpensesAmt0230385
IRS990/TotalProgramServiceRevenueAmt0223365
IRS990/TotalRevenueGrp/ExclusionAmt09060
IRS990/TotalRevenueGrp/RelatedOrExemptFuncIncomeAmt0223965
IRS990/TotalRevenueGrp/TotalRevenueColumnAmt0233025
IRS990/TotLiabNetAssetsFundBalanceGrp/BOYAmt01059231
IRS990/TotLiabNetAssetsFundBalanceGrp/EOYAmt01062343
IRS990/TravelGrp/ProgramServicesAmt01244
IRS990/TravelGrp/TotalAmt01244
IRS990/TrnsfrExmptNonChrtblRltdOrgInd0false
IRS990/TypeOfOrganizationCorpInd0X
IRS990/UnrelatedBusIncmOverLimitInd0false
IRS990/UponRequestInd0X
IRS990/USAddress/AddressLine1Txt01150 Walnut Street 2nd Floor
IRS990/USAddress/CityNm0Newton
IRS990/USAddress/StateAbbreviationCd0MA
IRS990/USAddress/ZIPCd002461
IRS990/VotingMembersGoverningBodyCnt057
IRS990/VotingMembersIndependentCnt057
IRS990/WebsiteAddressTxt0www.hupo.org
IRS990/WhistleblowerPolicyInd0false
ReturnHeader/BuildTS02025-03-06 01:10:19Z
ReturnHeader/BusinessOfficerGrp/DiscussWithPaidPreparerInd0true
ReturnHeader/BusinessOfficerGrp/PersonNm0Bernd Wollscheid
ReturnHeader/BusinessOfficerGrp/PersonTitleTxt0Treasurer
ReturnHeader/BusinessOfficerGrp/SignatureDt02025-09-01
ReturnHeader/Filer/BusinessName/BusinessNameLine1Txt0Human Proteome Organization - HUPO
ReturnHeader/Filer/BusinessNameControlTxt0HUMA
ReturnHeader/Filer/EIN0800814948
ReturnHeader/Filer/PhoneNum06045585498
ReturnHeader/Filer/USAddress/AddressLine1Txt01150 Walnut Street 2nd Floor
ReturnHeader/Filer/USAddress/CityNm0Newton
ReturnHeader/Filer/USAddress/StateAbbreviationCd0MA
ReturnHeader/Filer/USAddress/ZIPCd002461
ReturnHeader/IRSResponsiblePrtyInfoCurrInd0true
ReturnHeader/PreparerFirmGrp/PreparerFirmEIN0521268358
ReturnHeader/PreparerFirmGrp/PreparerFirmName/BusinessNameLine1Txt0Michael J Cavanaugh PA
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/AddressLine1Txt05603 Oakmont Avenue
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/CityNm0Bethesda
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/StateAbbreviationCd0MD
ReturnHeader/PreparerFirmGrp/PreparerUSAddress/ZIPCd020817
ReturnHeader/PreparerPersonGrp/PhoneNum03015649350
ReturnHeader/PreparerPersonGrp/PreparerPersonNm0Michael J Cavanaugh
ReturnHeader/ReturnTs02025-09-01T09:53:17-07:00
ReturnHeader/ReturnTypeCd0990
ReturnHeader/TaxPeriodBeginDt02024-01-01
ReturnHeader/TaxPeriodEndDt02024-12-31
ReturnHeader/TaxYr02024

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