The Ruth K Broad Biomedical Research Foundation Inc.

“5 individuals are family members of the late ruth k. Broad. Those individuals are: her daughter, ann b. Bussel; and her grandchildren, karen b. Berman, daniel j. Bussel, deborah l. Bussel and john m bussel.”

“The trustees of duke university have the authority to approve or disapprove nominations for directors of the ruth k. Broad biomedical research foundation, inc. Further, the trustees of duke university also have the authority to remove a director of the ruth k. Broad biomedical research foundation.”

“The trustees of duke university have the authority to approve or disapprove any decisions made by the governing body.”

“The ruth k. Broad biomedical research foundation, provides the members of the governing body with a draft of form 990 for individual review prior to filing.”

“The ruth k. Broad biomedical research foundation monitors and enforces compliance related to conflict of interest via the ruth k. Broad biomedical research foundation form 990 conflict of interest questionnaire. This questionnaire is sent out annually.”

“The ruth k. Broad biomedical research foundation form 990 is available to the public on www.guidestar.org. Guidestar independently posts tax-exempt organization's form 990's on their website, obtained from the internal revenue service.”

“The governing documents are available on the north carolina secretary of state website. The ruth k. Broad biomedical research foundation is included in the consolidated, independently audited financial statements of duke university, which are available at https://resources.finance.duke. Edu/resources/docs/financial_reports2018-19.pdf (weblink must be input in all lower case letters).”

“Investment fund duke university (and therefore the ruth k. Broad biomedical research foundation) manages its investment funds in accordance with the uniform prudent management of institutional funds act of north carolina. As permitted by the act, the university (and therefore the ruth k. Broad biomedical research foundation) utilizes two investment pools to invest its funds and these funds operate on a total return concept. It is, therefore, not possible to separate earnings as set forth on lines 3, 4, and 7c; earnings are combined and reported on line 7c.”

“The program as disclosed in part iii, line 4b was approved by the board during the fiscal year ended june 30, 2019, however, the activity will not begin until the following year.”

“Last year the organization endowed a professorship. The professorship was endowed to continue however, no further activity will take place by the organization.”

“Program service accomplishments the foundation continues to be committed to funding collaborative research in neurosciences at duke university school of medicine as well as at other academic medical centers. Funded are faculty principal investigators, postdoctoral fellows, and graduate students. The research is concerned with futhering the knowledge available about causes and potential treatments for alzheimer's disease and related neurological disorders. The foundation also funds the ruth k. Broad seminar series in neurobiology and disease, bringing noted scientists to duke's campus throughout the academic year to share research findings, to promote networking among the scientific community, and to mentor budding scientists. Results of grants awarded by the foundation are shared through this program as well. Results obtained throughout the funding period for the extramural principal investigator grant further defined the molecular interactions between the gene apoe4 and the alzheimer's disease factor ab. These experiments may provide mechanistic insights into the role of apoe4 as a risk factor for the development of alzheimer's disease. There were five lectures held as part of the 2018-2019 ruth k. Broad foundation seminar series. Topics included "systems genomics and gene networks in neuro-developmental and neurodegenerative disorders and "dissecting synaptic and circuitry mechanisms of psychiatric disorders."”

“The organization did not have unrelated business gross income of $1,000 or more during the fiscal year ended june 30, 2019. As a result, form 990-t is not required for the fiscal year ended june 30, 2019.”