Civic Intelligence

Cancer Prevention Initiative Inc.

990 • Fiscal year 2023 • EIN 47-3425850

Jan 01, 2023 to Dec 31, 2023 • Filed on May 13, 2024

Organization Profilewww.cancerpreventioninitiative.org
1722 Routh Street Suite 770Dallas, TX 75201

(844) 437-4891

Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

74th percentile

0.18x

Higher debt load relative to assets than 74% of similar nonprofits.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Source year 2023

Liabilities / Revenue

96th percentile

2.94x

Higher debt load relative to revenue than 96% of similar nonprofits.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Source year 2023

Net Margin

7th percentile

-50%

Higher net margin than 7% of similar nonprofits.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Source year 2023

Top Officer Pay

54th percentile

$0

Higher top officer pay than 54% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Source year 2023

Asset Growth

10th percentile

-22%

Faster asset growth than 10% of similar nonprofits.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Annualized from 2022 to 2023

Revenue Growth

2nd percentile

-81%

Faster revenue growth than 2% of similar nonprofits.

2023 filings • 501(c)3 • $500k-$1M nonprofits • Annualized from 2022 to 2023

Balance Sheet
Liabilities / Assets74th percentile

Assets

Down

$821,212

Down $234,984 (-22%) from 2022

Net Assets

Down

$675,216

Down $24,809 (-3.5%) from 2022

Liabilities

Down

$145,996

Down $210,175 (-59%) from 2022

Revenue And Expenses
Liabilities / Revenue96th percentileNet Margin7th percentile

Revenue

Down

$49,585

Down $207,483 (-81%) from 2022

Expenses

Up

$74,394

Up $55,976 (+304%) from 2022

Net Income

Down

-$24,809

Down $263,459 (-110%) from 2022

Historical Trend

Balance Sheet Trend

Asset Growth10th percentile

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$4.0M$3.0M$2.0M$1.0M$0Assets 2015: $416,306Liabilities 2015: $72,509Net Assets 2015: $343,7972015Assets 2016: $3,210,955Liabilities 2016: $133,500Net Assets 2016: $3,077,4552016Assets 2017: $2,944,284Liabilities 2017: $1,959,664Net Assets 2017: $984,6202017Assets 2018: $2,632,592Liabilities 2018: $985,352Net Assets 2018: $1,647,2402018Assets 2019: $1,943,615Liabilities 2019: $1,083,256Net Assets 2019: $860,3592019Assets 2020: $1,546,694Liabilities 2020: $777,428Net Assets 2020: $769,2662020Assets 2021: $962,671Liabilities 2021: $501,296Net Assets 2021: $461,3752021Assets 2022: $1,056,196Liabilities 2022: $356,171Net Assets 2022: $700,0252022Assets 2023: $821,212Liabilities 2023: $145,996Net Assets 2023: $675,2162023Assets 2024: $2,225,249Liabilities 2024: $580,179Net Assets 2024: $1,645,0702024

Highlighted filing

2023

Assets$821,212
Liabilities$145,996
Net Assets$675,216
Open 2023 Filing

Operations Trend

Revenue Growth2nd percentile

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$4.0M$2.0M$0-$2.0M-$4.0MRevenue 2015: $792,792Expenses 2015: $448,995Net Income 2015: $343,7972015Revenue 2016: $3,281,896Expenses 2016: $548,238Net Income 2016: $2,733,6582016Revenue 2017: $403,489Expenses 2017: $2,496,324Net Income 2017: -$2,092,8352017Revenue 2018: $1,224,228Expenses 2018: $561,608Net Income 2018: $662,6202018Revenue 2019: $297,410Expenses 2019: $1,084,291Net Income 2019: -$786,8812019Revenue 2020: $481,790Expenses 2020: $572,883Net Income 2020: -$91,0932020Revenue 2021: $151Expenses 2021: $308,042Net Income 2021: -$307,8912021Revenue 2022: $257,068Expenses 2022: $18,418Net Income 2022: $238,6502022Revenue 2023: $49,585Expenses 2023: $74,394Net Income 2023: -$24,8092023Revenue 2024: $1,673,681Expenses 2024: $703,827Net Income 2024: $969,8542024

Highlighted filing

2023

Revenue$49,585
Expenses$74,394
Net Income-$24,809
Open 2023 Filing
Jump To
Filing Snapshot
Filing Period
Jan 1, 2023 to Dec 31, 2023
Signed
May 13, 2024
Return Version
2023v5.0
Gross Receipts
$49,585
Mission and Program Overview

Mission

Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer. CPI uses its research, medical and pharmaceutical expertise to invest in first-rate science that will discover new strategies for preventing cancer. Our strategy is to support research on prevention of inherited cancers as a path towards elimination of all cancers. CPI acts as a facilitator to ensure that good ideas can find sufficient funding to turn them into therapeutic solutions such as drugs or vaccines to prevent cancer. CPI provides financial support, guidance and expertise throughout the research and development process to help researchers use the resources (donations) for the highest possible impact.

Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer.

Balance Sheet Detail
LineBeginningEndChange
Assets
Investments in Publicly Traded Securities$1,025,357$804,620▼ $220,737
Cash and Non-Interest-Bearing Accounts$1,165$6,759▲ $5,594
Intangible Assets$8,585$4,995▼ $3,590
Savings and Temporary Cash Investments$14,413$3,826▼ $10,587
Prepaid Expenses and Deferred Charges$6,676$1,012▼ $5,664
Accounts Receivable$0$0→ $0
Other Notes and Loans Receivable, Net$0$0→ $0
Pledges and Grants Receivable$0$0→ $0
Receivable From Disqualified Prsn$0$0→ $0
Receivables From Officers Etc$0$0→ $0
Investments Other Securities$0--
Investments Program Related$0--
Inventories for Sale or Use$0$0→ $0
Loans From Officers Directors$0$0→ $0
Total Assets$1,056,196$821,212▼ $234,984
Other Assets Total$0--
Liabilities
Grants Payable$356,078$145,000▼ $211,078
Accounts Payable and Accrued Expenses$93$955▲ $862
Other Liabilities-$41-
Mortgage Notes Payable Secured by Investment Property$0$0→ $0
Unsecured Notes Loans Payable$0--
Deferred Revenue$0$0→ $0
Escrow Account Liability$0$0→ $0
Tax Exempt Bond Liabilities$0$0→ $0
Total Liabilities$356,171$145,996▼ $210,175
Net Assets / Fund Balance
Net Assets With Donor Restrictions$464,764$411,398▼ $53,366
Net Assets Without Donor Restrictions$235,261$263,818▲ $28,557
Total Net Assets Fund Balance$700,025$675,216▼ $24,809
Total Liabilities and Net Assets / Fund Balance$1,056,196$821,212▼ $234,984
Compensation and Service Providers
Top Officer Pay54th percentile

Board Members and Trustees

NameTitle
Howard JanzenBoard Chair; Chief Financial Officer
Theodora RossPresident & Chief Scientific Officer
Douglas HagerTrustee, Sr. Vice President, Project Management and Operations
Kirk PatrickSecretary, Trustee
Jan Livingston-MokhtariTrustee
Joi MorrisTrustee
Revenue and Support

Revenue Composition

Contributions and Grants
$65
Program Service Revenue
$0
Investment Income
$49,520
Other Revenue
$0
All Other Contributions
$65
Change in Net Assets
$-24,809
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$53,367
Other Expenses$21,027
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$53,367--$53,367
Information Technology$5,682$320-$6,002
Office Expenses$0$4,430-$4,430
Depreciation Depletion-$3,590-$3,590
Fees for Services Accounting-$2,845-$2,845
Insurance-$2,586-$2,586
Other Expenses$0$1,599$0$1,599
Total Functional Expenses$59,049$15,345$0$74,394
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
University of Texas Southwestern Medical CenterDallas, TX-Scientific and administrative oversight of all Cancer Prevention Initiative programs.$200,000
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Loans from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Receivables from Disqualified Persons$0$0→ $0
Receivables from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Credit Card$41
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 8B

“Governing body has no committees with authority to act on behalf of the board.”

Form 990, Part VI, Section B, Line 11B

“All members of the governing body receive a copy of the 990 prior to filing, with the opportunity for input and questions.”

Form 990, Part VI, Section B, Line 12C

“The Board of Trustees annually reviews the Conflict of Interest policy and each covered person is annually required to sign a statement that discloses all potential conflicts of interest and affirms that such person: 1. Has received a copy of the Conflict of Interest Policy; 2. Has read and understand the Conflict of Interest policy; 3. Has agreed to comply with the Conflict of Interest Policy; 4. Understands that CPI is a charitable organization and that in order to maintain its federal tax exemption and the trust of the public it must diligently avoid conflicts of interest or the appearance of any conflict of interest and engage primarily in activities that accomplish one or more of its tax-exempt purposes.”

Form 990, Part VI, Section C, Line 19

“The organization complies with IRC Section 6104 in regard to public disclosure. As such, our annual information returns, Conflict of Interest Policy, audited financial reports, and governing documents are available for public inspection upon request.”

Filing and Contact Details

Filer

Filer Name
Cancer Prevention Initiative Inc
EIN
47-3425850
Phone
8444374891
Address
1722 Routh Street Suite 770, Dallas, TX 75201

Signing Officer

Name
Theodora Ross
Title
President
Phone
8444374891
Signed
2024-05-13

Organization Details

Principal Officer
Theodora Ross
Formed
2015
Legal Domicile
De
Voting Board Members
6
Independent Board Members
6
Employees
0
Volunteers
6
Supplemental Narrative

Additional Explanations

Form 990, Part IX, Line 1

“New grants made in 2023 totaled $200,000 (see Schedule I). This amount is offset by the return of $146,633.26 from a 2018 grant made to Johns Hopkins University. The grantee was unable to complete their contracted project. Net grant expenses for 2023 were $200,000 - $146,633 = $53,367.”

Raw XML AppendixShowing 400 of 448 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0In 2023, Cancer Prevention Initiative (CPI) opened an application cycle to identify new projects to fund. We accepted proposals pertaining to the therapeutic prevention of any inherited cancer, as we wish to expand our research portfolio beyond BRCA1/2 mutated cancers to all inherited cancers. We received applications covering all three strategic categories of research: Discovery research that expands the knowledge of early-pre-cancer stages and mechanisms of cancer initiation, development of early detection tests, and the development of chemo and/or immunotherapeutic agents. The response exceeded our expectations, with a total of 79 applications received. This volume indicates both the need for funding in this area and the enthusiasm of the research community to invest their discovery efforts in prevention. Also in 2023, CPI's ongoing research grant recipients have advanced towards greater understanding of preventing inherited cancers. Ongoing projects include Cleveland Clinic, where investigators seek to identify proteins uniquely and highly expressed in breast cancer of BRCA1 mutation carriers. Identification of these unique proteins is an important link for developing preventative vaccines. Also continuing is a project with Memorial Sloan Kettering Cancer Center to generate a robust cellular assay that would allow for the screening of hundreds of compounds to identify determinants of Loss of Heterozygosity (LoH) of BRCA genes. LoH is a major driver in cancer initiation, and discovery of compounds that cause LoH can be key for prevention discoveries. Other ongoing projects include Harvard's Beth Israel Deaconess Medical Center where they are working to identify cancer risk predictors in the reproductive epithelium in BRCA mutation carriers, and work at the University of Toronto to screen for drugs that can restore normal BRCA1 function to BRCA1 deficient cells.
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IRS990/Form990PartVIISectionAGrp/TitleTxt3Trustee
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IRS990/MissionDesc0Cancer Prevention Initiative, Inc. (CPI) is a nonprofit corporation whose mission is to accelerate the discovery and development of new medicines that prevent cancer. CPI uses its research, medical and pharmaceutical expertise to invest in first-rate science that will discover new strategies for preventing cancer. Our strategy is to support research on prevention of inherited cancers as a path towards elimination of all cancers. CPI acts as a facilitator to ensure that good ideas can find sufficient funding to turn them into therapeutic solutions such as drugs or vaccines to prevent cancer. CPI provides financial support, guidance and expertise throughout the research and development process to help researchers use the resources (donations) for the highest possible impact.
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IRS990/PrincipalOfficerNm0Theodora Ross
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IRS990/ProgSrvcAccomActy2Grp/Desc0Education and engagement programs: As we move closer to our goal of eradicating all cancers through preventative medicines, we believe that educating the public and raising awareness about inherited cancer syndromes will inspire more individuals to take proactive, life-saving preventive measures. One of the goals is to enhance the scientific reach of the organization and raise awareness on cancer prevention to a broader audience of patients, advocates and donors. Updates on scientific and medical research advances, recent clinical trials, and interviews with experts in cancer prevention are published on web-based platforms.
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IRS990/RoyaltiesRevenueGrp/UnrelatedBusinessRevenueAmt00
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IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus2YearsAmt0135
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus3YearsAmt0480096
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IRS990ScheduleA/GovtFurnSrvcFcltsVl170Grp/CurrentTaxYearMinus4YearsAmt00
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IRS990ScheduleD/OtherLiabilitiesOrgGrp/Desc0Credit Card
IRS990ScheduleD/TotalLiabilityAmt041
IRS990ScheduleI/GrantRecordsMaintainedInd01
IRS990ScheduleI/RecipientTable/CashGrantAmt0200000
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt0Scientific and administrative oversight of all Cancer Prevention Initiative programs.
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt0University of Texas Southwestern Medical Center
IRS990ScheduleI/RecipientTable/RecipientEIN0752556007
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt05323 Harry Hines Blvd
IRS990ScheduleI/RecipientTable/USAddress/CityNm0Dallas
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd0TX
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd075390
IRS990ScheduleI/SupplementalInformationDetail/ExplanationTxt0CPI conducts independent scientific peer review on all research applications before making grant award decisions. The Organization requires regular financial and narrative reports for all grant recipients on the use of grant funds and research conducted with the funds. Every grant contract contains specific research milestones and deliverables that are tracked throughout the research process. CPI's reporting requirements include reports on all research results and achievement of scheduled milestones. Annual financial reports must provide details regarding monies spent in comparison to the grant budget. Ongoing research payments are only authorized when milestones have been achieved and satisfactory research reports are received and approved by the scientific team.
IRS990ScheduleI/SupplementalInformationDetail/FormAndLineReferenceDesc0Schedule I, Part I, Line 2
IRS990ScheduleI/Total501c3OrgCnt01
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IRS990/ScheduleJRequiredInd00
IRS990/ScheduleORequiredInd01
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt0Governing body has no committees with authority to act on behalf of the board.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt1All members of the governing body receive a copy of the 990 prior to filing, with the opportunity for input and questions.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt2The Board of Trustees annually reviews the Conflict of Interest policy and each covered person is annually required to sign a statement that discloses all potential conflicts of interest and affirms that such person: 1. Has received a copy of the Conflict of Interest Policy; 2. Has read and understand the Conflict of Interest policy; 3. Has agreed to comply with the Conflict of Interest Policy; 4. Understands that CPI is a charitable organization and that in order to maintain its federal tax exemption and the trust of the public it must diligently avoid conflicts of interest or the appearance of any conflict of interest and engage primarily in activities that accomplish one or more of its tax-exempt purposes.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt3The organization complies with IRC Section 6104 in regard to public disclosure. As such, our annual information returns, Conflict of Interest Policy, audited financial reports, and governing documents are available for public inspection upon request.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt4New grants made in 2023 totaled $200,000 (see Schedule I). This amount is offset by the return of $146,633.26 from a 2018 grant made to Johns Hopkins University. The grantee was unable to complete their contracted project. Net grant expenses for 2023 were $200,000 - $146,633 = $53,367.
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc0Form 990, Part VI, Section A, Line 8b
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc1Form 990, Part VI, Section B, Line 11b
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc2Form 990, Part VI, Section B, Line 12c
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc3Form 990, Part VI, Section C, Line 19
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc4Form 990, Part IX, Line 1
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IRS990/TotalProgramServiceRevenueAmt00

Document Assets

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Filings

Displayed year

2023 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$821,212
Liabilities
$145,996
Net assets
$675,216
Revenue
$49,585
Expenses
$74,394
Net income
-$24,809
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2024Detailed filing. Detailed filing data is available for this year.$2.23$0.58$1.65$1.67$0.70$0.97
2023Detailed filing. Detailed filing data is available for this year.$0.82$0.15$0.68$0.05$0.07$0.02
2022Detailed filing. Detailed filing data is available for this year.$1.06$0.36$0.70$0.26$0.02$0.24
2021Detailed filing. Detailed filing data is available for this year.$0.96$0.50$0.46$0.00$0.31$0.31
2020Detailed filing. Detailed filing data is available for this year.$1.55$0.78$0.77$0.48$0.57$0.09
2019Summary only. Only limited summary data is available for this year.$1.94$1.08$0.86$0.30$1.08$0.79
2018Detailed filing. Detailed filing data is available for this year.$2.63$0.99$1.65$1.22$0.56$0.66
2017Detailed filing. Detailed filing data is available for this year.$2.94$1.96$0.98$0.40$2.50$2.09
2016Detailed filing. Detailed filing data is available for this year.$3.21$0.13$3.08$3.28$0.55$2.73
2015Summary only. Only limited summary data is available for this year.$0.42$0.07$0.34$0.79$0.45$0.34