Civic Intelligence

Altius Institute for Biomedical Sciences

EIN 47-2231080 • 501(c)3 • Seattle, WA

Profile

The mission of the altius institute for biomedical sciences (altius) is to advance the science of gene regulation for the benefit of human health. Altius aims to accomplish this mission by radically advancing biomedical discovery through the development and application of new technologies and approaches for illuminating cell and tissue functions in both health and disease states. To enable its mission, altius utilizes a new type of scientific and technological discovery environment designed to foster leaps in innovation by enabling its scientists to move from ideas to data faster than in any other academic or biotechnology setting. Altius continually strives to translate its data and technology into novel approaches for diagnosing and treating disease and for improving human health.

2211 Elliott Avenue 600Seattle, WA 98121

www.altiusinstitute.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

70th percentile

0.45x

Higher debt load relative to assets than 70% of similar nonprofits.

501(c)3 • $25M-$50M nonprofits • Source year 2024

Liabilities / Revenue

52nd percentile

0.30x

Higher debt load relative to revenue than 52% of similar nonprofits.

501(c)3 • $25M-$50M nonprofits • Source year 2024

Net Margin

9th percentile

-26%

Higher net margin than 9% of similar nonprofits.

501(c)3 • $25M-$50M nonprofits • Source year 2024

Top Officer Pay

92nd percentile

$925,296

Higher top officer pay than 92% of similar nonprofits.

Top officer pay equals 1.7% of source-year revenue.

501(c)3 • $25M-$50M nonprofits • Source year 2022

Asset Growth

2nd percentile

-34%

Faster asset growth than 2% of similar nonprofits.

501(c)3 • $25M-$50M nonprofits • Annualized from 2022 to 2024

Revenue Growth

7th percentile

-32%

Faster revenue growth than 7% of similar nonprofits.

501(c)3 • $25M-$50M nonprofits • Annualized from 2022 to 2024

Assets

Down

$17,386,206

Down $22,343,353 (-56%) from 2022

Liabilities

Down

$7,754,901

Down $5,471,257 (-41%) from 2022

Net Assets

Down

$9,631,305

Down $16,872,096 (-64%) from 2022

Revenue

Down

$25,521,018

Down $29,825,547 (-54%) from 2022

Expenses

Down

$32,275,657

Down $21,889,675 (-40%) from 2022

Net Income

Down

-$6,754,639

Down $7,935,872 (-672%) from 2022

Trend Graphs

Balance Sheet Trend

Grouped bars show assets, liabilities, and net assets across loaded filings.

$80M$60M$40M$20M$0Assets 2016: $21,682,398Liabilities 2016: $8,902,692Net Assets 2016: $12,779,7062016Assets 2017: $26,358,989Liabilities 2017: $12,624,203Net Assets 2017: $13,734,7862017Assets 2018: $19,497,322Liabilities 2018: $7,651,704Net Assets 2018: $11,845,6182018Assets 2019: $17,764,328Liabilities 2019: $9,778,672Net Assets 2019: $7,985,6562019Assets 2020: $20,723,085Liabilities 2020: $8,197,072Net Assets 2020: $12,526,0132020Assets 2021: $61,078,390Liabilities 2021: $37,458,008Net Assets 2021: $23,620,3822021Assets 2022: $39,729,559Liabilities 2022: $13,226,158Net Assets 2022: $26,503,4012022Assets 2024: $17,386,206Liabilities 2024: $7,754,901Net Assets 2024: $9,631,3052024

Highlighted filing

2024

Assets$17,386,206
Liabilities$7,754,901
Net Assets$9,631,305

Operations Trend

Revenue, expenses, and net income by year, with the latest filing highlighted.

$60M$40M$20M$0-$20MRevenue 2016: $27,959,116Expenses 2016: $20,271,920Net Income 2016: $7,687,1962016Revenue 2017: $22,821,561Expenses 2017: $21,866,481Net Income 2017: $955,0802017Revenue 2018: $21,469,277Expenses 2018: $23,358,445Net Income 2018: -$1,889,1682018Revenue 2019: $16,965,373Expenses 2019: $20,825,335Net Income 2019: -$3,859,9622019Revenue 2020: $25,217,625Expenses 2020: $22,201,302Net Income 2020: $3,016,3232020Revenue 2021: $44,158,765Expenses 2021: $33,064,396Net Income 2021: $11,094,3692021Revenue 2022: $55,346,565Expenses 2022: $54,165,332Net Income 2022: $1,181,2332022Revenue 2024: $25,521,018Expenses 2024: $32,275,657Net Income 2024: -$6,754,6392024

Highlighted filing

2024

Revenue$25,521,018
Expenses$32,275,657
Net Income-$6,754,639

Filings

Latest Detailed Filing

The latest 2024 filing currently has linked XML that has not been fully parsed yet. Showing the latest detailed filing from 2022 below.

Jump To
Filing Snapshot
Filing Period
Jan 1, 2022 to Dec 31, 2022
Signed
Nov 14, 2023
Return Version
2022v5.0
Gross Receipts
$55,545,324
Mission and Program Overview

Mission

The mission of the altius institute for biomedical sciences (altius) is to radically enable and advance biomedical discovery through the development and exploratory application of new technologies and approaches for illuminating cell and tissue states and function. To achieve this vision, altius is establishing a wholly new type of scientific and technological discovery environment designed to foster leaps in innovation. Altius will leverage its cutting-edge technologies to span the chasm between basic biological discoveries related to the function of cells and tissues and the translation of these insights into the clinical arena and the development of novel medicines.

To advance the science of gene regulation for the benefit of human health.

Balance Sheet Detail
LineBeginningEndChange
Assets
Land, Buildings, and Equipment, Net$12,472,040$13,088,404▲ $616,364
Savings and Temporary Cash Investments$6,014,193$12,665,062▲ $6,650,869
Accounts Receivable$38,513,962$1,749,718▼ $36,764,244
Cash and Non-Interest-Bearing Accounts$2,252,615$1,538,455▼ $714,160
Prepaid Expenses and Deferred Charges$1,547,727$1,447,796▼ $99,931
Inventories for Sale or Use$247,428$885,540▲ $638,112
Intangible Assets$16,225$16,225→ $0
Total Assets$61,078,390$39,729,559▼ $21,348,831
Other Assets Total$14,200$8,338,359▲ $8,324,159
Liabilities
Other Liabilities$243,615$8,243,689▲ $8,000,074
Accounts Payable and Accrued Expenses$8,641,581$4,283,083▼ $4,358,498
Deferred Revenue$28,572,812$699,386▼ $27,873,426
Total Liabilities$37,458,008$13,226,158▼ $24,231,850
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$23,620,382$26,503,401▲ $2,883,019
Total Net Assets Fund Balance$23,620,382$26,503,401▲ $2,883,019
Total Liabilities and Net Assets / Fund Balance$61,078,390$39,729,559▼ $21,348,831

Asset Categories

AssetBook ValueDepreciationBasis
Equipment$7,314,316$10,822,214$18,136,530
Leasehold Improvements$4,984,064$2,040,534$7,024,598
Other Land Buildings$790,024$864,198$1,654,222
Other Assets Org$8,280,159--
Compensation and Service Providers

Employees

NameTitleFull / Part TimeBaseOtherTotal
John StamatoyannopoulosScientific Director & TreasurerFT$879,375$45,921$925,296
Alister FunnellDeputy DirectorFT$600,000$51,596$651,596
Chad LundbergChief of StaffFT$534,375$42,245$576,620
Michael CockrillChief Technology OfficerFT$396,667$68,461$465,128
Jeffrey VierstraPrincipal InvestigatorFT$309,375$56,854$366,229
Lori TonnesGeneral Counsel & SecretaryFT$278,333$61,856$340,189
Wouter MeulemanPrincipal InvestigatorFT$275,000$61,254$336,254
Peter HandrinosBoard Member-$47,500-$47,500
Harry DietzBoard Member-$47,500-$47,500

Board Members and Trustees

NameTitle
Christopher MillerBoard Member
John LeporeBoard Member

Highest Paid Contractors

ContractorServicesLocationCompensation
Keith GrochowSoftware Engineering1425 BROADWAY, Seattle, WA 98122$149,150
Revenue and Support

Revenue Composition

Contributions and Grants
$42,586,134
Program Service Revenue
$12,797,574
Investment Income
$-128,964
Other Revenue
$91,821
All Other Contributions
$41,046,151
Change in Net Assets
$1,181,233
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Other Expenses$35,448,848
Salaries, Compensation, and Employee Benefits$18,716,484
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Other Salaries and Wages$11,415,331$2,534,142-$13,949,473
Fees for Services Other$3,585,939$1,978,149-$5,564,088
Depreciation Depletion$4,220,413--$4,220,413
Occupancy$2,205,953$252,971-$2,458,924
Information Technology$1,946,962$263,420-$2,210,382
Other Employee Benefits$1,178,140$224,782-$1,402,922
Current Officers, Directors, Trustees, and Key Employees$972,796$387,689-$1,360,485
Payroll Taxes$826,456$193,860-$1,020,316
Pension Plan Contributions$796,463$186,825-$983,288
Fees for Services Legal$542,677--$542,677
Office Expenses$34,298$349,817-$384,115
Travel-$282,914-$282,914
Other Expenses$2,070$264,231-$266,301
Fees for Services Accounting-$188,877-$188,877
Insurance-$138,595-$138,595
Conferences and Meetings-$8,841-$8,841
Total Functional Expenses$46,910,219$7,255,113$0$54,165,332
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Debt and Bond Financing

Other Reported Liabilities

LiabilityAmount
Lease Liability$8,243,689
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Audit committee
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
Yes
Other officer compensation reviewed
Yes
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
Yes
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 6

The organization has one class of membership which includes two members, dr. John stamatoyannopoulos (or his designee) and glaxosmithkline llc.

Form 990, Part VI, Section A, Line 7A

The members of the organization are entitled to elect directors of the board and remove only directors which they have appointed.

Form 990, Part VI, Section A, Line 7B

The glaxosmithkline llc member may elect and remove glaxosmithkline llc directors of the board while john stamatoyannopoulos as a member may elect and remove john stamatoyannopoulos directors of the board. Common directors of the board are elected and removed by unanimous action of john stamatoyannopoulos and glaxosmithkline llc members.

Form 990, Part VI, Section B, Line 11B

The president/scientific director, audit committee, and general counsel will review the form 990 prior to its submission to the irs.

Form 990, Part VI, Section B, Line 12C

The organization's conflict of interest policy requires covered persons, defined as any director, officer, or member of a committee of the board of directors, to complete and sign an annual conflict of interest questionnaire. The questionnaire requires disclosure of any potential or actual conflicts of interest and is signed by the covered person, affirming that the individual has received a copy of, read, understands, and will comply with the organization's conflict of interest policy. If a potential or actual conflict of interest arises, the individual must recuse himself or herself from voting on the matter and must not be present when any such vote is taken. The board of directors evaluates all disclosures reported to determine whether an actual conflict of interest exists. Potential or actual conflicts of interest are documented in the minutes of meetings of the board of directors and committee's of the board.

Form 990, Part VI, Section B, Line 15

A compensation study was conducted by an outside consultant in 2021 to determine the compensation for the president. The compensation study was approved by the compensation committee. The study is effective through 2022. The next study is in the process of being compiled.

Form 990, Part VI, Section C, Line 19

The governing documents, conflict of interest policy and financial statements are made available to the public upon request.

Filing and Contact Details

Filer

Filer Name
Altius Institute for Biomedical Sciences
EIN
47-2231080
Phone
2062671091
Address
2211 ELLIOTT AVENUE 600, SEATTLE, WA 98121

Signing Officer

Name
John Stamatoyannopoulos
Title
President/scientific Director
Phone
2062671091
Signed
2023-11-14
Discuss with paid preparer
Yes

Organization Details

Principal Officer
John Stamatoyannopoulos
Formed
2014
Legal Domicile
De
Voting Board Members
4
Independent Board Members
3
Employees
156
Volunteers
2

Preparer

Firm
Clark Nuber Ps
Address
10900 NE 4TH STREET SUITE 1400, BELLEVUE, WA 98004
Preparer
Sara Elizabeth H Jones
Phone
4254544919
Supplemental Narrative

Additional Explanations

FORM 990, PART I, LINE 6:

The volunteer is made up of two uncompensated board members.

Form 990, Part IX, Line 11G

Contract services: program service expenses 398,600. Management and general expenses 1,451,477. Fundraising expenses 0. Total expenses 1,850,077. Recruiting costs: program service expenses 0. Management and general expenses 169,112. Fundraising expenses 0. Total expenses 169,112. Board fees: program service expenses 0. Management and general expenses 100,000. Fundraising expenses 0. Total expenses 100,000. Other professional fees: program service expenses 3,187,339. Management and general expenses 257,560. Fundraising expenses 0. Total expenses 3,444,899.

PART IX, FUNCTIONAL EXPENSE ALLOCATION:

All expenses associated with obtaining grants are included in program and general and administrative expenses as allowed under the indirect cost recovery provisions of the grant agreement.

FORM 990, PART XI, LINE 9:

Add'l revenue recognized on py audited financials after filing of form 990 1,271,798. Reversal of over accrued prior year expense 429,988.

PART XII, LINE 2B:

The organization's financial statement audit has not been finalized at the time of the tax return filing.

Raw XML AppendixShowing 400 of 620 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0ALTIUS DIRECTLY CONDUCTS AN ACTIVE AND MULTIFACETED PROGRAM OF BASIC SCIENCE RESEARCH IN THE FIELDS OF GENETICS, GENOMICS, AND BIOTECHNOLOGY. WE CONDUCT THE MAJORITY OF RESEARCH PROGRAMS DIRECTLY IN OUR OWN LABORATORIES LOCATED IN SEATTLE, WASHINGTON, AND ALSO COLLABORATE WITH ACADEMIC RESEARCH HOSPITALS. ALTIUS AIMS TO DISCOVER, DEVELOP, AND TRANSLATE FOR CLINICAL USE BOTH DATA AND TRANSFORMATIVE TECHNOLOGIES THAT ILLUMINATE OR ENABLE THE CONTROL OF HUMAN GENES IN MEDICALLY IMPORTANT BIOLOGICAL CONTEXTS. OUR RESEARCH PROGRAMS FOCUS ON GAINING A RICHER UNDERSTANDING OF HUMAN CELL FUNCTION IN HEALTH AND DISEASE FOR THE PURPOSE OF DEVELOPING NEW APPROACHES TO DIAGNOSIS AND THERAPY. TOWARD THESE GOALS, ALTIUS RESEARCH PROGRAM FOCUSES ON THE DEVELOPMENT, SCALING AND TRANSLATIONAL APPLICATION OF DIVERSE TECHNOLOGY PLATFORMS, INCLUDING GENETIC AND GENOMIC ANALYSES, CELL AND GENOME ENGINEERING, SINGLE MOLECULE DNA AND CHROMATIN ANALYSIS, AND HIGH-RESOLUTION CELL IMAGING. THESE TECHNOLOGIES PROVIDE NEW WINDOWS INTO CELLULAR RESPONSES AND THEY COLLECTIVELY OPEN NEW DOORS TO THE DISCOVERY OF NEW MEDICINES.IN RESPONSE TO THE PANDEMIC AND RELATED DISASTER DECLARATION, ALTIUS LEVERAGED ITS SCIENTIFIC EXPERTISE TO CREATE AND PROVIDE COVID-19 GENETIC TESTING SERVICES UNDER EMERGENCY CONTRACTS WITH GOVERNMENTAL AGENCIES. THESE SERVICES WERE FUNDED DIRECTLY OR INDIRECTLY BY ONE-TIME EMERGENCY APPROPRIATIONS WITHOUT CHARGE TO END RECIPIENTS. ALTIUS ALSO PROVIDED COVID-19 GENETIC TESTING SERVICES TO LOCAL AND NONPROFIT EDUCATIONAL ORGANIZATIONS. IN ADDITION, ALTIUS UTILIZED DATA FROM ITS GENETIC TESTING TO CONDUCT RESEARCH INTO COVID-19 EPIDEMIOLOGY AND VARIANTS IN COLLABORATION WITH GOVERNMENTAL AGENCIES AND ACADEMIC INSTITUTIONS.
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IRS990/Form990PartVIISectionAGrp/TitleTxt8CHIEF TECHNOLOGY OFFICER
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IRS990/Form990PartVIISectionAGrp/TitleTxt10PRINCIPAL INVESTIGATOR
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IRS990/MissionDesc0THE MISSION OF THE ALTIUS INSTITUTE FOR BIOMEDICAL SCIENCES (ALTIUS) IS TO ADVANCE THE SCIENCE OF GENE REGULATION FOR THE BENEFIT OF HUMAN HEALTH. ALTIUS AIMS TO ACCOMPLISH THIS MISSION BY RADICALLY ADVANCING BIOMEDICAL DISCOVERY THROUGH THE DEVELOPMENT AND APPLICATION OF NEW TECHNOLOGIES AND APPROACHES FOR ILLUMINATING CELL AND TISSUE FUNCTIONS IN BOTH HEALTH AND DISEASE STATES. TO ENABLE ITS MISSION, ALTIUS UTILIZES A NEW TYPE OF SCIENTIFIC AND TECHNOLOGICAL DISCOVERY ENVIRONMENT DESIGNED TO FOSTER LEAPS IN INNOVATION BY ENABLING ITS SCIENTISTS TO MOVE FROM IDEAS TO DATA FASTER THAN IN ANY OTHER ACADEMIC OR BIOTECHNOLOGY SETTING. ALTIUS CONTINUALLY STRIVES TO TRANSLATE ITS DATA AND TECHNOLOGY INTO NOVEL APPROACHES FOR DIAGNOSING AND TREATING DISEASE AND FOR IMPROVING HUMAN HEALTH.
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