Civic Intelligence

Grace Science Foundation

990 • Fiscal year 2020 • EIN 46-5727883

Jan 01, 2020 to Dec 31, 2020 • Filed on Nov 11, 2021

1142 Crane St 4Menlo Park, CA 94025

(415) 255-7666

Siviq Scores

Precomputed percentiles for this filing year versus similar nonprofits in the same peer cohort.

Liabilities / Assets

16th percentile

0.00x

Higher debt load relative to assets than 16% of similar nonprofits.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Source year 2020

Liabilities / Revenue

16th percentile

0.00x

Higher debt load relative to revenue than 16% of similar nonprofits.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Source year 2020

Net Margin

37th percentile

0.1%

Higher net margin than 37% of similar nonprofits.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Source year 2020

Top Officer Pay

37th percentile

$0

Higher top officer pay than 37% of similar nonprofits.

Top officer pay equals 0.0% of source-year revenue.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Source year 2020

Asset Growth

31st percentile

-0.2%

Faster asset growth than 31% of similar nonprofits.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Annualized from 2019 to 2020

Revenue Growth

37th percentile

-6.9%

Faster revenue growth than 37% of similar nonprofits.

2020 filings • 501(c)3 • $1M-$5M nonprofits • Annualized from 2019 to 2020

Assets

Down

$2,884,506

Down $5,109 (-0.2%) from 2019

Net Assets

Down

$2,884,120

Down $3,294 (-0.1%) from 2019

Liabilities

Down

$386

Down $1,815 (-82%) from 2019

Revenue

Down

$1,454,180

Down $107,122 (-6.9%) from 2019

Expenses

Up

$1,452,901

Up $613,506 (+73%) from 2019

Net Income

Down

$1,279

Down $720,628 (-100%) from 2019

Historical Trend

Balance Sheet Trend

The highlighted filing sits inside the broader history for assets, liabilities, and net assets.

$4.0M$3.0M$2.0M$1.0M$0Assets 2014: $603,778Liabilities 2014: $0Net Assets 2014: $603,7782014Assets 2015: $1,605,814Liabilities 2015: $0Net Assets 2015: $1,605,8142015Assets 2016: $1,336,131Liabilities 2016: $0Net Assets 2016: $1,336,1312016Assets 2017: $2,109,224Liabilities 2017: $16,500Net Assets 2017: $2,092,7242017Assets 2018: $2,196,374Liabilities 2018: $0Net Assets 2018: $2,196,3742018Assets 2019: $2,889,615Liabilities 2019: $2,201Net Assets 2019: $2,887,4142019Assets 2020: $2,884,506Liabilities 2020: $386Net Assets 2020: $2,884,1202020Assets 2021: $3,128,030Liabilities 2021: $29,929Net Assets 2021: $3,098,1012021Assets 2022: $3,183,591Liabilities 2022: $51,224Net Assets 2022: $3,132,3672022Assets 2023: $2,790,274Liabilities 2023: $42,997Net Assets 2023: $2,747,2772023Assets 2024: $2,224,370Liabilities 2024: $1,004Net Assets 2024: $2,223,3662024

Highlighted filing

2020

Assets$2,884,506
Liabilities$386
Net Assets$2,884,120

Operations Trend

Revenue, expenses, and net income across loaded years, with this filing highlighted.

$2.0M$1.0M$0-$1.0MRevenue 2014: $664,490Expenses 2014: $60,712Net Income 2014: $603,7782014Revenue 2015: $1,560,381Expenses 2015: $558,345Net Income 2015: $1,002,0362015Revenue 2016: $600,124Expenses 2016: $869,807Net Income 2016: -$269,6832016Revenue 2017: $1,677,107Expenses 2017: $920,514Net Income 2017: $756,5932017Revenue 2018: $1,199,988Expenses 2018: $1,074,064Net Income 2018: $125,9242018Revenue 2019: $1,561,302Expenses 2019: $839,395Net Income 2019: $721,9072019Revenue 2020: $1,454,180Expenses 2020: $1,452,901Net Income 2020: $1,2792020Revenue 2021: $1,327,113Expenses 2021: $1,113,132Net Income 2021: $213,9812021Revenue 2022: $1,236,228Expenses 2022: $1,218,482Net Income 2022: $17,7462022Revenue 2023: $826,626Expenses 2023: $1,289,174Net Income 2023: -$462,5482023Revenue 2024: $943,011Expenses 2024: $1,519,386Net Income 2024: -$576,3752024

Highlighted filing

2020

Revenue$1,454,180
Expenses$1,452,901
Net Income$1,279
Jump To
Filing Snapshot
Filing Period
Jan 1, 2020 to Dec 31, 2020
Signed
Nov 11, 2021
Return Version
2020v4.1
Gross Receipts
$1,454,180
Mission and Program Overview

Mission

The mission of the foundation is to support and fund the development of life-saving treatment for patients that are deficient in the n-glycanese enzyme and those suffering from related genetic diseases. The activities of the foundation will involve providing grant funding to hospitals and medical research facilities which are conducting medical research in various fields relating to the search for understanding and treatment of this condition, and fostering collaboration between academia, research institutions, hospitals, private companies, and governmental agencies.

The mission of the foundation is to support and fund the development of life-saving treatment for patients that are deficient in the n-glycanese enzyme and those suffering from related genetic diseases.

Balance Sheet Detail
LineBeginningEndChange
Assets
Cash and Non-Interest-Bearing Accounts$2,885,541$2,884,506▼ $1,035
Rtn Earn Endowment Incm Other Fnds$2,887,414$2,884,120▼ $3,294
Investments in Publicly Traded Securities$4,074--
Pd in Cap Srpls Land Bldg Eqp Fund$0$0→ $0
Cap Stk Tr Prin Current Funds$0$0→ $0
Total Assets$2,889,615$2,884,506▼ $5,109
Liabilities
Accounts Payable and Accrued Expenses$2,201$386▼ $1,815
Total Liabilities$2,201$386▼ $1,815
Net Assets / Fund Balance
Total Net Assets Fund Balance$2,887,414$2,884,120▼ $3,294
Total Liabilities and Net Assets / Fund Balance$2,889,615$2,884,506▼ $5,109
Compensation and Service Providers

Board Members and Trustees

NameTitle
Matthew WilseyPresident
Chelsea ClintonDirector
Elle StephensDirector
J Taylor CrandallDirector
Pete BrigerDirector
Egon DurbanChief Financial Officer
Ken DrazanSecretary
Revenue and Support

Revenue Composition

Contributions and Grants
$1,447,474
Program Service Revenue
$0
Investment Income
$6,706
Other Revenue
$0
All Other Contributions
$1,447,474
Change in Net Assets
$1,279
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Grants and Similar Amounts Paid$1,373,067
Other Expenses$79,834
Professional Fundraising Fees$0
Salaries, Compensation, and Employee Benefits$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Grants to Domestic Orgs$1,354,317--$1,354,317
Fees for Services Other-$53,551-$53,551
Foreign Grants$18,750--$18,750
Advertising-$11,225-$11,225
Fees for Services Legal-$5,100-$5,100
Office Expenses$2,823--$2,823
Insurance-$955-$955
Travel$147--$147
Other Expenses-$31-$31
Total Functional Expenses$1,376,037$76,864$0$1,452,901
International Activity

Grant and Assistance Recipients

RecipientLocationCategoryPurposeAmount
Charles River LaboratoriesWilmington, MA501(c)(3)Ngly1 Rat Model$516,323
Stanford UniversityPalo Alto, CA501(c)(3)Ngly1 Work in Bertozzi/snyder/steinmetz Labs & Natural History Protocol Development$375,347
University of Texas Southwestern Medical CenterDallas, TX501(c)(6)Ngly1 Work in Yan Lab$279,337
Salk Institute for Biological StudiesLa Jolla, CA501(c)(3)Ngly1 Work in Gage Lab$82,810
Massachusetts General HospitalBoston, MA501(c)(3)Nygly1 Work in Rukvun Lab$79,250
New York Stem Cell FoundationNew York, NY-Ngly1 Stem Cell Lines$21,250

International Summary

Offices
0
Employees
0
Spending
$0

International Compliance

Activity in boycott countries
No
Foreign corporation ownership
No
Foreign partnership interest
No
Interest in foreign trust
No
Passive foreign investment company interest
No
Transfers to foreign corporations
No
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
No
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section A, Line 2

The president of the foundation has immaterial ownership interest, in the investments of fortress and silver lake, which are managed by two of the directors.

Form 990, Part VI, Section A, Line 7A

The president of the foundation has authority to elect one or more members of the governing body.

Form 990, Part VI, Section A, Line 8A

The governing body of the foundation did not meet during the year.

Form 990, Part VI, Section A, Line 8B

The foundation does not have any committees.

Form 990, Part VI, Section B, Line 11B

Prior to filing from 990, the foundation's president will review the form.

Form 990, Part VI, Section C, Line 18

AVAILABLE UPON REQUEST.

Form 990, Part VI, Section C, Line 19

AVAILABLE UPON REQUEST.

Filing and Contact Details

Filer

Filer Name
Grace Science Foundation
EIN
46-5727883
Phone
4152557666
Address
1142 CRANE ST 4, MENLO PARK, CA 94025

Signing Officer

Name
Matthew R Wilsey
Title
President
Phone
4152557666
Signed
2021-11-11
Discuss with paid preparer
Yes

Organization Details

Principal Officer
Matthew R Wilsey
Formed
2014
Legal Domicile
CA
Voting Board Members
7
Independent Board Members
7
Employees
0
Volunteers
0

Preparer

Firm
Withumsmithbrown Pc
Address
601 CALIFORNIA STREET SUITE 1800, SAN FRANCISCO, CA 94108
Preparer
Bradford Weisert
Phone
4154343744
Supplemental Narrative

Additional Explanations

FORM 990, PART XI, LINE 9:

Prior period adjustment -4,573.

Raw XML AppendixShowing 400 of 450 raw XML fields

This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.

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IRS990/Desc0UNIVERSITY OF TEXAS SOUTHWESTERN (YAN LAB) - TEAM HAS BEEN GENERATING AND CHARACTERIZING SEVERAL MOUSE MODELS OF NGLY1 DEFICIENCY, INCLUDING MODELS IN WHICH THE GENE IS INACTIVATED IN CERTAIN TISSUES AND CONDITIONALLY AFTER BIRTH. THESE MOUSE MODELS HAVE ALLOWED THEM TO CHARACTERIZE NEUROLOGICAL PHENOTYPES, NEUROPATHOLOGICAL CHANGES, INFLAMMATION, SENSORY AND MOTOR DEFECTS, AND DISEASE ASSOCIATED BIOMARKERS. THESE ANIMAL MODELS PROVIDE INSIGHTS INTO THE SPECIFIC DEFECTS THAT RESULT FROM NGLY1 LOSS AND ESTABLISH A FOUNDATION FOR TESTING CANDIDATE THERAPIES, INCLUDING GENE THERAPIES AND SMALL MOLECULE DRUGS. THE TEAM HAS ALSO FOUND THAT NGLY1 DEFICIENCY IN MICE TRIGGERS A SPECIFIC INNATE IMMUNE PATHWAY MEDIATED BY THE CGAS/STING PATHWAY. THEY HAVE BEEN USING GENETIC AND PHARMACOLOGICAL APPROACHES TO TEST WHETHER ACTIVATED STING SIGNALLING CONTRIBUTES TO THE PATHOLOGY ASSOCIATED WITH NGLY1 DEFICIENCY AND WHETHER BLOCKING THIS PATHWAY PROVIDES THERAPEUTIC BENEFIT.
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IRS990/Form990PartVIISectionAGrp/TitleTxt0PRESIDENT
IRS990/Form990PartVIISectionAGrp/TitleTxt1CHIEF FINANCIAL OFFICER
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IRS990/Form990PartVIISectionAGrp/TitleTxt3DIRECTOR
IRS990/Form990PartVIISectionAGrp/TitleTxt4DIRECTOR
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IRS990/MissionDesc0THE MISSION OF THE FOUNDATION IS TO SUPPORT AND FUND THE DEVELOPMENT OF LIFE-SAVING TREATMENT FOR PATIENTS THAT ARE DEFICIENT IN THE N-GLYCANESE ENZYME AND THOSE SUFFERING FROM RELATED GENETIC DISEASES. THE ACTIVITIES OF THE FOUNDATION WILL INVOLVE PROVIDING GRANT FUNDING TO HOSPITALS AND MEDICAL RESEARCH FACILITIES WHICH ARE CONDUCTING MEDICAL RESEARCH IN VARIOUS FIELDS RELATING TO THE SEARCH FOR UNDERSTANDING AND TREATMENT OF THIS CONDITION, AND FOSTERING COLLABORATION BETWEEN ACADEMIA, RESEARCH INSTITUTIONS, HOSPITALS, PRIVATE COMPANIES, AND GOVERNMENTAL AGENCIES.
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IRS990/ProgSrvcAccomActy2Grp/Desc0STANFORD UNIVERSITY NGLY1 NATURAL HISTORY STUDY (MAURA RUZHNIKOV) - TEAM IS CONDUCTING AN NGLY1 NATURAL HISTORY STUDY TO DEFINE THE CLINICAL SPECTRUM OF THE DISEASE AND ITS PROGRESSION, AS WELL AS BIOMARKER ENDPOINTS FOR USE IN THERAPEUTIC TRIALS. THIS STUDY IS LED BY DR. MAURA RUZHNIKOV, MD, A CHILD NEUROLOGIST AND MEDICAL GENETICIST FOCUSED ON THE DIAGNOSIS AND MANAGEMENT OF RARE NEUROLOGIC DISORDERS, INCLUDING GENETIC EPILEPSY SYNDROMES, CHILDHOOD NEURODEGENERATIVE DISEASES, AND UNDIAGNOSED SUSPECTED GENETIC CONDITIONS. TEAM HAS DEVELOPED AND RECEIVED APPROVAL FOR THE STUDY DESIGN, RECRUITED PARTICIPANTS, AND GATHERED UP TO 2 YEARS OF CLINICAL DATA FROM SEVERAL PATIENTS. AS OF THE END OF 2020, THE STUDY HAS ENROLLED TWENTY-NINE INDIVIDUALS CONFIRMED TO HAVE NGLY1 DEFICIENCY AS EITHER ON-SITE OR REMOTE PARTICIPANTS. ULTIMATELY THE STUDY WILL FOLLOW THE PARTICIPANTS LONGITUDINALLY OVER FIVE YEARS.
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IRS990/ProgSrvcAccomActy3Grp/Desc0CHARLES RIVER LABORATORIES - TEAM HAS IMPORTED AND ESTABLISHED A COLONY OF NGLY1 KNOCKOUT RATS FOR USE IN TESTING THERAPIES TO TREAT NGLY1 DEFICIENCY. A BREEDING COLONY HAS BEEN ESTABLISHED, MUTANT PHENOTYPES HAVE BEEN CHARACTERIZED, AND WORK IS UNDERWAY TO USE THESE MODELS TO TEST ADENO-ASSOCIATED VIRUS (AAV)-MEDIATED GENE DELIVERY FOR RESCUE OF DISEASE-ASSOCIATED PHENOTYPES. THIS WORK WILL SERVE AS THE FOUNDATION FOR AN INVESTIGATIONAL NEW DRUG (IND) APPLICAITON TO THE FDA FOR AN NGLY1 DEFICIENCY GENE THERAPY CLINICAL STUDY; THE FINDINGS COULD ALSO SUPPORT TRIALS FOR OTHER THERAPEUTIC AVENUES FOR TREATING NGLY1 DEFICIDENCY
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IRS990/ProgSrvcAccomActyOtherGrp/Desc0SALK INSTITUTE FOR BIOLOICAL SCIENCES (GAGE LAB) - TEAM HAS CONTINUED THEIR DEVELOPMENT AND STUDY OF INDUCED PLURIPOTENT STEM CELLS (IPSCS) FROM NGLY1 DEFICIENT PATIENTS AS A MODEL SYSTEM TO CHARACTERIZE THE FUNCTIONAL CHANGES CAUSED BY NGLY1 LOSS AND TO TEST CANDIDATE THERAPIES FOR REVERSING THESE CHANGES. THEY OBSERVED THE PRESENCE OF PROTEIN AGGREGATES, MITOCHONDIAL DYSFUNCTION, AND REDUCED SYNAPTIC ACTIVITY IN NEURONS DERIVED FROM PATIENT IPSCS COMPARED WITH CONTROLS. THE TEAM HAS VERIFIED THAT THESE PHENOTYPIC CHANGES ARE RESUCED BY REINTRODUCING A FUNCTIONAL HUMAN NGLY1 GENE INTO THE CELLS, AND HAS BEEN CHARACTERIZING THE COMPOSITION OF THE AGGREGATES FOUND IN NGLY1 DEFICIENT CELLS. THESE DISCOVERIES IDENTIFIED PHENOTYPES THAT CAN BE LEVERAGED FOR HIGH-THROUGHPUT DRUG SCREENS AND PROVIDE INSIGHT AS TO THE CELL TYPES AFFECTED BY THE DISEASE IN PATIENTS.
IRS990/ProgSrvcAccomActyOtherGrp/Desc1MASSACHUSETTS GENERAL HOSPITAL (RUVKUN LAB) - TEAM CONTINUED THEIR ANALYSIS OF THE GENETIC MODIFIERS OF PROTEASOME DYSFUNCTION THAT THEY PREVIOUSLY IDENTIFIED IN PNG-1 / NGLY1 DEFICIENT C. ELEGANS. THIS LED TO THE IDENTIFICATION OF SEVERAL PATHWAYS WHOSE DISRUPTION APPEARS BENEFICIAL TO PROTEASOME DYSFUNCTION IN NGLY1 DEFICIENT ANIMALS, A FINDING THAT COULD TRANSLATE INTO A POTENTIAL THERAPY FOR THE DISEASE IN HUMANS. THEY ALSO DEMONSTRATED NGLY1 HAS A CRITICAL FUNCTION GIVEN ITS ABILITY TO EDIT THE PROTEIN SEQUENCE OF ONE OF ITS KEY SUBSTRATES, THE TRANSCRIPTIONAL REGULATOR SKN-1A / NFE2L1, AND THEREBY REGULATE NFE2L1'S FUNCTION IN MAINTAINING PROTEIN HOMEOSTASIS IN THE CELL. ADDITIONALLY, THE TEAM DEMONSTRATED THAT SKN-1A / NFE2L1 IS ACTIVATED BY MISFOLDED PROTEINS, A FINDING WITH POTENTIAL RELEVANCE TO NEURODEGENERATIVE DISEASES. COLLECTIVELY, THESE RESULTS LED TO THREE PUBLICATIONS IN INFLUENTIAL JOURNALS.
IRS990/ProgSrvcAccomActyOtherGrp/Desc2THE NEW YORK STEM CELL FOUNDATION - TEAM IS DEVELOPING ADDITIONAL PATIENT-DERIVED INDUCED PLURIPOTENT STELL CELL (IPSC) LINES TO COMPLEMENT AND EXPAND HUMAN CELL MODELS OF NGLY1 DEFICIENCY. CRISPR-MEDIATED GENOME EDITING WILL BE USED TO PRODUCE ISOGENIC LINES FOR USE AS A CONTROL TO DETEMINE DISEASE-SPECIFIC CHARACTERISTICS. THESE LINES WILL SERVE AS ADDITIONAL MODELS FOR TESTING POTENTIAL THERAPIES TO REVERSE PATHOLOGIES ASSOCIATED WITH NGLY1 DEFICIENCY.
IRS990/ProgSrvcAccomActyOtherGrp/Desc3OTHER PROGRAM SERVICES ARE RELATED TO RESEARCH AND DEVELOMENT TO UNDERSTAND AND CURE DISEASES BEGINNING WITH NGLY1 DEFICIENCY
IRS990/ProgSrvcAccomActyOtherGrp/ExpenseAmt083305
IRS990/ProgSrvcAccomActyOtherGrp/ExpenseAmt179745
IRS990/ProgSrvcAccomActyOtherGrp/ExpenseAmt221745
IRS990/ProgSrvcAccomActyOtherGrp/ExpenseAmt318750
IRS990/ProgSrvcAccomActyOtherGrp/GrantAmt082811
IRS990/ProgSrvcAccomActyOtherGrp/GrantAmt179250
IRS990/ProgSrvcAccomActyOtherGrp/GrantAmt221250
IRS990/ProgSrvcAccomActyOtherGrp/GrantAmt318750
IRS990/ProhibitedTaxShelterTransInd00
IRS990/PYBenefitsPaidToMembersAmt00
IRS990/PYContributionsGrantsAmt01522789
IRS990/PYExcessBenefitTransInd00
IRS990/PYGrantsAndSimilarPaidAmt0709424
IRS990/PYInvestmentIncomeAmt038513
IRS990/PYOtherExpensesAmt0129971
IRS990/PYOtherRevenueAmt00
IRS990/PYProgramServiceRevenueAmt00
IRS990/PYRevenuesLessExpensesAmt0721907
IRS990/PYSalariesCompEmpBnftPaidAmt00
IRS990/PYTotalExpensesAmt0839395
IRS990/PYTotalProfFndrsngExpnsAmt00
IRS990/PYTotalRevenueAmt01561302
IRS990/QuidProQuoContributionsInd00
IRS990/ReconcilationRevenueExpnssAmt01279
IRS990/RegularMonitoringEnfrcInd00
IRS990/RelatedEntityInd00
IRS990/RelatedOrganizationCtrlEntInd00
IRS990/ReportInvestmentsOtherSecInd00
IRS990/ReportLandBuildingEquipmentInd00
IRS990/ReportOtherAssetsInd00
IRS990/ReportOtherLiabilitiesInd00
IRS990/ReportProgramRelatedInvstInd00
IRS990/RtnEarnEndowmentIncmOthFndsGrp/BOYAmt02887414
IRS990/RtnEarnEndowmentIncmOthFndsGrp/EOYAmt02884120
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearAmt01447474
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus1YearAmt01522789
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus2YearsAmt01157365
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus3YearsAmt01677107
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus4YearsAmt0600124
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/TotalAmt06404859
IRS990ScheduleA/PublicOrganization170Ind0X
IRS990ScheduleA/PublicSupportCY170Pct00.65640
IRS990ScheduleA/PublicSupportPY170Pct00.62200
IRS990ScheduleA/PublicSupportTotal170Amt04203901
IRS990ScheduleA/SubstantialContributorsTotAmt02200958
IRS990ScheduleA/ThirtyThrPctSuprtTestsCY170Ind0X
IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearAmt01447474
IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus1YearAmt01522789
IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus2YearsAmt01157365
IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus3YearsAmt01677107
IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus4YearsAmt0600124
IRS990ScheduleA/TotalCalendarYear170Grp/TotalAmt06404859
IRS990ScheduleA/TotalSupportAmt06404859
IRS990ScheduleB/ContributorInformationGrp/ContributorBusinessName/BusinessNameLine10RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorNum0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine10RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine20RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/City0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/State0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/ZIPCode0RESTRICTED
IRS990ScheduleB/ContributorInformationGrp/TotalContributionsAmt0RESTRICTED
IRS990/ScheduleBRequiredInd01
IRS990ScheduleF/BoycottCountriesInd00
IRS990ScheduleF/ContinuationSpentAmt00
IRS990ScheduleF/ContinuationTotalEmployeeCnt00
IRS990ScheduleF/ContinuationTotalOfficeCnt00
IRS990ScheduleF/ForeignCorpOwnershipInd00
IRS990ScheduleF/ForeignPartnershipInd00
IRS990ScheduleF/GrantsToOrgOutsideUSGrp/CashGrantAmt018750
IRS990ScheduleF/GrantsToOrgOutsideUSGrp/MannerOfCashDisbursementTxt0CHECK
IRS990ScheduleF/GrantsToOrgOutsideUSGrp/PurposeOfGrantTxt0NGYL1 WORK IN MOFFAT'S LABS AT UNIVERSITY OF TORONTO
IRS990ScheduleF/GrantsToOrgOutsideUSGrp/RegionTxt0CANADA
IRS990ScheduleF/InterestInForeignTrustInd00
IRS990ScheduleF/PassiveForeignInvestmestCoInd00
IRS990ScheduleF/SubtotalEmployeesCnt00
IRS990ScheduleF/SubtotalOfficesCnt00
IRS990ScheduleF/SubtotalSpentAmt00
IRS990ScheduleF/SupplementalInformationDetail/FormAndLineReferenceDesc0PART III ACCOUNTING METHOD:
IRS990ScheduleF/TotalEmployeeCnt00
IRS990ScheduleF/TotalOfficeCnt00
IRS990ScheduleF/TotalSpentAmt00
IRS990ScheduleF/TransferToForeignCorpInd00
IRS990ScheduleI/GrantRecordsMaintainedInd01
IRS990ScheduleI/RecipientTable/CashGrantAmt0375347
IRS990ScheduleI/RecipientTable/CashGrantAmt179250
IRS990ScheduleI/RecipientTable/CashGrantAmt282810
IRS990ScheduleI/RecipientTable/CashGrantAmt3279337
IRS990ScheduleI/RecipientTable/CashGrantAmt4516323
IRS990ScheduleI/RecipientTable/CashGrantAmt521250
IRS990ScheduleI/RecipientTable/IRCSectionDesc0501(C)(3)
IRS990ScheduleI/RecipientTable/IRCSectionDesc1501(C)(3)
IRS990ScheduleI/RecipientTable/IRCSectionDesc2501(C)(3)
IRS990ScheduleI/RecipientTable/IRCSectionDesc3501(C)(6)
IRS990ScheduleI/RecipientTable/IRCSectionDesc4501(C)(3)
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt0NGLY1 WORK IN BERTOZZI/SNYDER/STEINMETZ LABS & NATURAL HISTORY PROTOCOL DEVELOPMENT
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt1NYGLY1 WORK IN RUKVUN LAB
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt2NGLY1 WORK IN GAGE LAB
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt3NGLY1 WORK IN YAN LAB
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt4NGLY1 RAT MODEL
IRS990ScheduleI/RecipientTable/PurposeOfGrantTxt5NGLY1 STEM CELL LINES
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt0STANFORD UNIVERSITY
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt1MASSACHUSETTS GENERAL HOSPITAL
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt2SALK INSTITUTE FOR BIOLOGICAL STUDIES
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt3UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt4CHARLES RIVER LABORATORIES
IRS990ScheduleI/RecipientTable/RecipientBusinessName/BusinessNameLine1Txt5NEW YORK STEM CELL FOUNDATION
IRS990ScheduleI/RecipientTable/RecipientEIN0941156365
IRS990ScheduleI/RecipientTable/RecipientEIN1041564655
IRS990ScheduleI/RecipientTable/RecipientEIN2952160097
IRS990ScheduleI/RecipientTable/RecipientEIN3756002868
IRS990ScheduleI/RecipientTable/RecipientEIN4202905531
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt03145 PORTER DRIVE
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt132 FRUIT ST
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt210010 N TORREY PINES ROAD
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt35323 HARRY HINES BLVD
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt4251 BALLARDVALE ST
IRS990ScheduleI/RecipientTable/USAddress/AddressLine1Txt5619 W 54TH STREET
IRS990ScheduleI/RecipientTable/USAddress/CityNm0PALO ALTO
IRS990ScheduleI/RecipientTable/USAddress/CityNm1BOSTON
IRS990ScheduleI/RecipientTable/USAddress/CityNm2LA JOLLA
IRS990ScheduleI/RecipientTable/USAddress/CityNm3DALLAS
IRS990ScheduleI/RecipientTable/USAddress/CityNm4WILMINGTON
IRS990ScheduleI/RecipientTable/USAddress/CityNm5NEW YORK
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd0CA
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd1MA
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd2CA
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd3TX
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd4MA
IRS990ScheduleI/RecipientTable/USAddress/StateAbbreviationCd5NY
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd094304
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd102114
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd292037
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd375390
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd401887
IRS990ScheduleI/RecipientTable/USAddress/ZIPCd510019
IRS990ScheduleI/SupplementalInformationDetail/ExplanationTxt0* BEFORE FUNDING A PRINCIPAL INVESTIGATOR, THE FOUNDATION REQUIRES A DETAILED PROPOSAL WITH OBJECTIVES AND MILESTONES * THE PROPOSALS ARE REVIEWED BY THE FOUNDATION AND SCIENTIFIC ADVISORY BOARD * THE PROPOSALS ARE OFTEN REVISED SEVERAL TIMES TO GET THE CORRECT FIT * ONCE FUNDED, EACH PRINCIPAL INVESTIGATOR SUBMITS A WRITTEN SUMMARY EVERY QUARTER * THIS UPDATE IS TWO TO THREE PAGES IN LENGTH * THE REPORTS DISCUSS PROGRESS, HIGHLIGHT ROADBLOCKS AND IDENTIFY WHERE THEY NEED HELP * THE FOUNDATION STEPS-IN WHERE APPROPRIATE TO MAKE SURE OBJECTIVES AND MILESTONES ARE MET * IN ADDITION TO QUARTERLY REPORTS, THE FOUNDATION HOLDS A MONTHLY CONFERENCE CALL WHERE TWO TO THREE PRINCIPAL INVESTIGATORS PRESENT THEIR LATEST WORK * BEYOND THE ABOVE TWO INITIATIVES, THE FOUNDATION HOLDS ONE TO TWO IN-PERSON MEETINGS PER YEAR * DR. KEVIN LEE (CHIEF SCIENTIFIC OFFICER), DR. SELINA DWIGHT (PROGRAM MANAGER), AND MATT WILSEY(PRESIDENT) CONTACT RESEARCHERS AND PRINCIPAL INVESTIGATORS ON A REGULAR BASIS VIA EMAIL, PHONE, OR ONE ON ONE MEETINGS THE PRESIDENT ENSURES THAT EVERY DOLLAR IS USED TO SUPPORT THE GRACE SCIENCE FOUNDATION'S MISSION.
IRS990ScheduleI/SupplementalInformationDetail/FormAndLineReferenceDesc0PART I, LINE 2:
IRS990/ScheduleJRequiredInd00
IRS990/ScheduleORequiredInd01
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt0THE PRESIDENT OF THE FOUNDATION HAS IMMATERIAL OWNERSHIP INTEREST, IN THE INVESTMENTS OF FORTRESS AND SILVER LAKE, WHICH ARE MANAGED BY TWO OF THE DIRECTORS.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt1THE PRESIDENT OF THE FOUNDATION HAS AUTHORITY TO ELECT ONE OR MORE MEMBERS OF THE GOVERNING BODY.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt2THE GOVERNING BODY OF THE FOUNDATION DID NOT MEET DURING THE YEAR.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt3THE FOUNDATION DOES NOT HAVE ANY COMMITTEES.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt4PRIOR TO FILING FROM 990, THE FOUNDATION'S PRESIDENT WILL REVIEW THE FORM.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt5AVAILABLE UPON REQUEST.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt6AVAILABLE UPON REQUEST.
IRS990ScheduleO/SupplementalInformationDetail/ExplanationTxt7PRIOR PERIOD ADJUSTMENT -4,573.
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc0FORM 990, PART VI, SECTION A, LINE 2
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc1FORM 990, PART VI, SECTION A, LINE 7A
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc2FORM 990, PART VI, SECTION A, LINE 8A
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc3FORM 990, PART VI, SECTION A, LINE 8B
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc4FORM 990, PART VI, SECTION B, LINE 11B
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc5FORM 990, PART VI, SECTION C, LINE 18
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc6FORM 990, PART VI, SECTION C, LINE 19
IRS990ScheduleO/SupplementalInformationDetail/FormAndLineReferenceDesc7FORM 990, PART XI, LINE 9:
IRS990/SchoolOperatingInd00
IRS990/SignificantChangeInd00
IRS990/SignificantNewProgramSrvcInd00
IRS990/StatesWhereCopyOfReturnIsFldCd0CA
IRS990/SubjectToExcsTaxNetInvstIncInd00
IRS990/SubjectToProxyTaxInd00
IRS990/SubjToTaxRmnrtnExPrchtPymtInd00
IRS990/TaxablePartyNotificationInd00
IRS990/TaxExemptBondsInd00
IRS990/TerminateOperationsInd00
IRS990/TotalAssetsBOYAmt02889615
IRS990/TotalAssetsEOYAmt02884506
IRS990/TotalAssetsGrp/BOYAmt02889615
IRS990/TotalAssetsGrp/EOYAmt02884506
IRS990/TotalCompGreaterThan150KInd00
IRS990/TotalContributionsAmt01447474
IRS990/TotalEmployeeCnt00
IRS990/TotalFunctionalExpensesGrp/FundraisingAmt00
IRS990/TotalFunctionalExpensesGrp/ManagementAndGeneralAmt076864
IRS990/TotalFunctionalExpensesGrp/ProgramServicesAmt01376037
IRS990/TotalFunctionalExpensesGrp/TotalAmt01452901
IRS990/TotalGrossUBIAmt00
IRS990/TotalLiabilitiesBOYAmt02201
IRS990/TotalLiabilitiesEOYAmt0386
IRS990/TotalLiabilitiesGrp/BOYAmt02201
IRS990/TotalLiabilitiesGrp/EOYAmt0386
IRS990/TotalNetAssetsFundBalanceGrp/BOYAmt02887414
IRS990/TotalNetAssetsFundBalanceGrp/EOYAmt02884120
IRS990/TotalOtherCompensationAmt00
IRS990/TotalOtherProgSrvcExpenseAmt0203545
IRS990/TotalOtherProgSrvcGrantAmt0202061
IRS990/TotalProgramServiceExpensesAmt01376037
IRS990/TotalReportableCompFromOrgAmt00
IRS990/TotalRevenueGrp/ExclusionAmt06706
IRS990/TotalRevenueGrp/RelatedOrExemptFuncIncomeAmt00
IRS990/TotalRevenueGrp/TotalRevenueColumnAmt01454180
IRS990/TotalRevenueGrp/UnrelatedBusinessRevenueAmt00
IRS990/TotalVolunteersCnt00

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