Biopontis Alliance for Rare Disease Foundation In

“Expenses dues and subscriptions 48 bank service charges 36 contributions-liquidate 688 total 772”

“Pledges receivable 10,937 0 total 10,937 0”

“Accounts payable and accrued expenses 18,329 0”

“The biopontis alliance rare disease foundation is a nonprofit corporation that brings together rare disease patient advocacy organizations, academic research centers, contract research companies, and the biomedical industry to translate research into potential treatments by focusing on the earliest stages of product development.”

“Alliances and partnerships -- during 2019, the biopontis alliance organization mainly worked on the realization of the promise of our first strategic partnership, which is the project with vib (flemish institute for biotechnology, belgium) and the university of antwerp, belgium on a clinical variant of the peripheral neuropathy charcot-marie- tooth disease. Together with our partners, we have worked on the identification of compounds from a large compound bank, owned by our partners, through assay development and high-throughput screening techniques. That work led to several 'hits', in other words, several compounds that may, after further validation and optimization, potentially be used for the development of a therapy. This positive development not only validates the overall approach taken by the biopontis alliance, but also provides a promising platform for further work towards a potential therapy for the indicated rare disease. We also worked with our partners on the definition of the next steps needed towards therapy development.”