Liabilities / Assets
98th percentile
Higher debt load relative to assets than 98% of similar nonprofits.
EIN 46-2953382 • 501(c)3 • San Diego, CA
Profile
The Institute is a scientific research center dedicated to conducting basic and applied research to advance the understanding of human disease and the improvement of human health. The Institute fosters an innovative research environment with a multidisciplinary and collaborative approach to the discovery process - bringing together physical and life science researchers, clinicians, engineers/ and computational scientists to address the significant health care challenges of heart and vascular disease, obesity, and metabolic disorders through a multi-scale understanding of organ systems. Institute researchers have expertise in both experimental and computational disciplines. The former utilizes the experimental reductionist approach to dissect the biological system into its molecular, cellular and tissue components. The latter use a computational integrative approach to synthesize the parts using laws of physics and chemistry to understand the whole organ. The Institutes multi-discipline
Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.
Liabilities / Assets
98th percentile
Higher debt load relative to assets than 98% of similar nonprofits.
Liabilities / Revenue
74th percentile
Higher debt load relative to revenue than 74% of similar nonprofits.
Net Margin
20th percentile
Higher net margin than 20% of similar nonprofits.
Top Officer Pay
82nd percentile
Higher top officer pay than 82% of similar nonprofits.
Top officer pay equals 4.1% of source-year revenue.
Asset Growth
5th percentile
Faster asset growth than 5% of similar nonprofits.
Revenue Growth
37th percentile
Faster revenue growth than 37% of similar nonprofits.
Assets
Down$1,865,081
Down $768,776 (-29%) from 2023
Liabilities
Down$2,869,590
Down $185,721 (-6.1%) from 2023
Net Assets
Down-$1,004,509
Down $583,055 (-138%) from 2023
Revenue
Up$6,104,330
Up $38,785 (+0.6%) from 2023
Expenses
Up$6,687,385
Up $143,380 (+2.2%) from 2023
Net Income
Down-$583,055
Down $104,595 (-22%) from 2023
Most recent year
2024 • Form 990Detailed filing. Detailed filing data is available for this year.
The Institute is a scientific research center dedicated to conducting basic and applied research to advance the understanding of human disease and the improvement of human health. The Institute fosters an innovative research environment with a multidisciplinary and collaborative approach to the discovery process - bringing together physical and life science researchers, clinicians, engineers/ and computational scientists to address the significant health care challenges of heart and vascular disease, obesity, and metabolic disorders through a multi-scale understanding of organ systems. Institute researchers have expertise in both experimental and computational disciplines. The former utilize the experimental reductionist approach to dissect the biological system into its molecular, cellular and tissue components. The latter use a computational integrative approach to synthesize the parts using laws of physics and chemistry to understand the whole organ. The Institutes multi-discipline
Bringing together physical and life science researchers, clinicians, engineers/ and computational scientists to address the significant health care challenges of heart and vascular disease, obesity, and metabolic disorders through a multi-scale understanding of organ systems.
| Line | Beginning | End | Change |
|---|---|---|---|
| Assets | |||
| Pledges and Grants Receivable | $1,126,563 | $1,063,433 | ▼ $63,130 |
| Cash and Non-Interest-Bearing Accounts | $676,539 | $526,881 | ▼ $149,658 |
| Land, Buildings, and Equipment, Net | $34,415 | $59,364 | ▲ $24,949 |
| Prepaid Expenses and Deferred Charges | $16,884 | $16,430 | ▼ $454 |
| Inventories for Sale or Use | $10,472 | $9,436 | ▼ $1,036 |
| Savings and Temporary Cash Investments | - | $0 | - |
| Accounts Receivable | - | $0 | - |
| Other Notes and Loans Receivable, Net | - | $0 | - |
| Receivable From Disqualified Prsn | - | $0 | - |
| Receivables From Officers Etc | - | $0 | - |
| Investments Other Securities | - | $0 | - |
| Investments Program Related | - | $0 | - |
| Investments in Publicly Traded Securities | - | $0 | - |
| Intangible Assets | - | $0 | - |
| Total Assets | $2,633,857 | $1,865,081 | ▼ $768,776 |
| Other Assets Total | $768,984 | $189,537 | ▼ $579,447 |
| Liabilities | |||
| Mortgage Notes Payable Secured by Investment Property | $1,929,086 | $1,875,611 | ▼ $53,475 |
| Accounts Payable and Accrued Expenses | $329,563 | $720,045 | ▲ $390,482 |
| Other Liabilities | $779,951 | $273,934 | ▼ $506,017 |
| Deferred Revenue | $16,711 | - | - |
| Total Liabilities | $3,055,311 | $2,869,590 | ▼ $185,721 |
| Net Assets / Fund Balance | |||
| Net Assets With Donor Restrictions | $546,116 | $120,498 | ▼ $425,618 |
| Net Assets Without Donor Restrictions | $-967,570 | $-1,125,007 | ▼ $157,437 |
| Total Net Assets Fund Balance | $-421,454 | $-1,004,509 | ▼ $583,055 |
| Total Liabilities and Net Assets / Fund Balance | $2,633,857 | $1,865,081 | ▼ $768,776 |
| Asset | Book Value | Depreciation | Basis |
|---|---|---|---|
| Equipment | $59,364 | $1,350,243 | $1,409,607 |
| Other Assets Org | $146,752 | - | - |
| Name | Title | Full / Part Time | Base | Other | Total |
|---|---|---|---|---|---|
| Ghassan Kassab | Chairman | PT | $196,075 | $51,355 | $247,430 |
| Bhavesh Patel | Assc Research Prof | FT | $183,964 | $31,864 | $215,828 |
| Jenny Choy | Research Professor | FT | $143,103 | $27,248 | $170,351 |
| Ismail Qaddoura | It Manager | FT | $111,393 | $35,126 | $146,519 |
| Sanjay Soundarajan | Assc Research Prof | FT | $121,194 | $17,971 | $139,165 |
| Christopher Marroquin | Software Developer | FT | $107,000 | $17,384 | $124,384 |
| Hans Gregersen | President & CEO | FT | $91,031 | $24,413 | $115,444 |
| Name | Title |
|---|---|
| Abdulkader Rahmo | Board Member |
| Julius Guccione | Board Member |
| Contractor | Services | Location | Compensation |
|---|---|---|---|
| 3dt Holdings | Research Services | 11107 ROSELLE ST STE 213, San Diego, CA 92121 | $260,819 |
| Line Item | Amount |
|---|---|
| Other Expenses | $3,922,977 |
| Salaries, Compensation, and Employee Benefits | $2,764,408 |
| Grants and Similar Amounts Paid | $0 |
| Professional Fundraising Fees | $0 |
| Total Fundraising Expense | $0 |
| Line Item | Program | Management | Fundraising | Total |
|---|---|---|---|---|
| Other Salaries and Wages | $1,572,830 | $221,984 | - | $1,794,814 |
| Occupancy | $590,944 | $79,816 | - | $670,760 |
| Current Officers, Directors, Trustees, and Key Employees | $221,849 | $141,025 | - | $362,874 |
| Other Employee Benefits | $222,439 | $48,362 | - | $270,801 |
| Pension Plan Contributions | $149,384 | $32,459 | - | $181,843 |
| All Other Expenses | $139,276 | $28,564 | - | $167,840 |
| Payroll Taxes | $126,573 | $27,503 | - | $154,076 |
| Fees for Services Other | $81,960 | $61,121 | - | $143,081 |
| Other Expenses | $135,116 | $2,684 | - | $137,800 |
| Travel | $48,524 | $22,883 | - | $71,407 |
| Office Expenses | $28,485 | $3,822 | - | $32,307 |
| Insurance | $28,038 | $3,787 | - | $31,825 |
| Fees for Services Legal | $7,365 | $23,617 | - | $30,982 |
| Depreciation Depletion | $18,437 | $2,490 | - | $20,927 |
| Fees for Services Accounting | - | $18,100 | - | $18,100 |
| Total Functional Expenses | $5,950,963 | $736,422 | $0 | $6,687,385 |
| Line Item | Amount |
|---|---|
| Expenses per Audited Statements | $6,687,385 |
| Total Expenses per Audited Statements | $6,687,385 |
| Total Expenses per Form 990 | $6,687,385 |
| Line Item | Amount |
|---|---|
| Professional Fundraising Fees | $0 |
| Interested Party | Relationship | Description | Shared Revenue | Amount |
|---|---|---|---|---|
| 3dt Holdings LLC | CEO Family Owned | Rent of Facility | No | $252,138 |
| - | CEO Part Owner | Vendor Services | No | $141,069 |
| - | CEO 50% | Services | No | $61,559 |
| Line Item | Beginning | End | Change |
|---|---|---|---|
| Receivables from Disqualified Persons | - | $0 | - |
| Receivables from Officers, Directors, Trustees, and Key Employees | - | $0 | - |
| Liability | Amount |
|---|---|
| Operating Lease Liability | $164,898 |
| Accrued Payroll | $109,036 |
“The Form 990 will be reviewed by Senior Management, President, Board of Directors and outside counsel.”
“The board of directors has adopted two written conflict of interest policies. Thefirst policy (the financial conflict of interest policy) is applicable to officersand directors of the institute. Each officer and each member of the board ofdirectors is required to review and acknowledge their understanding of the financialconflict of interest policy upon appointment to office or to the board. Officersand directors are routinely encouraged to bring any and all potential conflicts ofinterest to the attention of the disinterested board members for review.the second policy (the research conflict policy) is applicable to researchersparticipating in any of the institutes federally funded grants. Researchers arerequired to review the research conflict policy and complete a training program onfinancial conflicts of interest in research at least every four years. Theinstitute takes very seriously its obligation to report any financial conflicts ofinterest to the national institute of health and encourages all researchers to fullydisclose any and all potential conflicts for review by the independent members ofthe board of directors. To the extent that the independent members of the board ofdirectors determine that a significant conflict exists, the following conditions andrestrictions could be imposed: public disclosure of the conflict, monitoring of theresearch by independent reviewers, modification of the research plan or removal ofthe affected researcher from the research, divestiture of significant financial interests, or severance of the relationship that creates the actual or potentialconflicts.”
“The presidents compensation was reviewed and approved by the disinterested members of the board of directors on december 31, 2016. The approved compensation package consists of a base amount, plus incentive bonuses upon successful funding of research grants or contracts, plus contributions to retirement plan. In determining whether the total amount of compensation was reasonable, the disinterested members of the board reviewed and discussed the proposed compensation arrangement and carefully considered the background, education, professional experience, skills and achievements of dr. Ghassan kassab, the unique qualities to the institute to fill the position of president and chief scientific officer, and the reports of compensation levels paid by other similar organizations according to the economic institute report. The disinterested members of the board also reviewed and relied upon the opinion of counsel that the compensation proposed to be paid to dr. Kassab was within the range that would be expected for an employee with dr. Kassabs unique expertise, performing the specified duties for an organization of the size of the institute. The decision of the board of directors was documented in a written consent. Dr. Kassab abstained from the vote. No changes to the presidents compensation package have been made since december 31, 2016. However, in 2019, 2020 and 2021, the president was eligible for certain bonus awards pursuant to the terms of the previously approved compensation package.”
“The Institute makes its application and return available to the public upon request.”
“The Institute makes its governing documents, conflicts of interest policies, and financial statements available to the public upon request.”
“The institutes financial statements are audited by an independent accountant on an annual basis. Rather than appointing a smaller committee to oversee the audit process, the entire board assumes the oversight responsibility for the audit process. Specifically, the board selected an independent accountant after reviewing the qualifications and proposals from at least two independent accountants, considering the federal procurement standards applicable to the selection of external audit firms, and considering the best interests of the institute. The independent accountant reports the findings of the audit directly to the board on an annual basis, during which time any audit deficiencies are disclosed and discussed.”
“The Institute is a public charity and is exempt from income taxes under Section 501(c)(3) of the Internal Revenue Code and Section 23701(d) of the California Revenue and Taxation Code. The Institute believes that it has appropriate support for any tax positions taken, and as such, does not have any uncertain tax positions that are material to the financial statements. The Institute is not a private foundation.”
This appendix keeps the raw XML leaves available for debugging and edge-case review. The human report above is the primary experience.
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| IRS990/AccountsPayableAccrExpnssGrp/EOYAmt | 0 | 720045 |
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| IRS990/ActivityOrMissionDesc | 0 | Bringing together physical and life science researchers, clinicians, engineers/ and computational scientists to address the significant health care challenges of heart and vascular disease, obesity, and metabolic disorders through a multi-scale understanding of organ systems. |
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| IRS990/AllOtherExpensesGrp/ProgramServicesAmt | 0 | 139276 |
| IRS990/AllOtherExpensesGrp/TotalAmt | 0 | 167840 |
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| IRS990/BooksInCareOfDetail/USAddress/CityNm | 0 | SAN DIEGO |
| IRS990/BooksInCareOfDetail/USAddress/StateAbbreviationCd | 0 | CA |
| IRS990/BooksInCareOfDetail/USAddress/ZIPCd | 0 | 92121 |
| IRS990/BusinessRlnWith35CtrlEntInd | 0 | false |
| IRS990/BusinessRlnWithFamMemInd | 0 | false |
| IRS990/BusinessRlnWithOrgMemInd | 0 | false |
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| IRS990/CashNonInterestBearingGrp/EOYAmt | 0 | 526881 |
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| IRS990/CompCurrentOfcrDirectorsGrp/TotalAmt | 0 | 362874 |
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| IRS990/CompensationProcessCEOInd | 0 | true |
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| IRS990/ConflictOfInterestPolicyInd | 0 | true |
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| IRS990/ConsolidatedAuditFinclStmtInd | 0 | false |
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| IRS990/ContractorCompensationGrp/ContractorAddress/USAddress/CityNm | 0 | SAN DIEGO |
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| IRS990/ContractorCompensationGrp/ContractorName/BusinessName/BusinessNameLine1Txt | 0 | 3DT HOLDINGS |
| IRS990/ContractorCompensationGrp/ServicesDesc | 0 | RESEARCH SERVICES |
| IRS990/CreditCounselingInd | 0 | false |
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| IRS990/CYGrantsAndSimilarPaidAmt | 0 | 0 |
| IRS990/CYInvestmentIncomeAmt | 0 | 28311 |
| IRS990/CYOtherExpensesAmt | 0 | 3922977 |
| IRS990/CYOtherRevenueAmt | 0 | 574 |
| IRS990/CYProgramServiceRevenueAmt | 0 | 168529 |
| IRS990/CYRevenuesLessExpensesAmt | 0 | -583055 |
| IRS990/CYSalariesCompEmpBnftPaidAmt | 0 | 2764408 |
| IRS990/CYTotalExpensesAmt | 0 | 6687385 |
| IRS990/CYTotalFundraisingExpenseAmt | 0 | 0 |
| IRS990/CYTotalProfFndrsngExpnsAmt | 0 | 0 |
| IRS990/CYTotalRevenueAmt | 0 | 6104330 |
| IRS990/DecisionsSubjectToApprovaInd | 0 | false |
| IRS990/DeductibleArtContributionInd | 0 | false |
| IRS990/DeductibleNonCashContriInd | 0 | false |
| IRS990/DeferredRevenueGrp/BOYAmt | 0 | 16711 |
| IRS990/DelegationOfMgmtDutiesInd | 0 | false |
| IRS990/DepreciationDepletionGrp/ManagementAndGeneralAmt | 0 | 2490 |
| IRS990/DepreciationDepletionGrp/ProgramServicesAmt | 0 | 18437 |
| IRS990/DepreciationDepletionGrp/TotalAmt | 0 | 20927 |
| IRS990/Desc | 0 | THE INSTITUTE HAS MADE SUBSTANTIAL PROGRESS IN MORE FULLY UNDERSTANDING, ANDDEVELOPING DIAGNOSTIC AND THERAPEUTIC APPROACHES FOR THE MULTIPLE ASPECTS OF HEART FAILURE. THE INSTITUTE HAS ALSO MADE SIGNIFICANT PROGRESS IN THE UNDERSTANDING ANDTREATMENT OF VASCULAR DISEASE, INCLUDING WORK ADVANCING NEXT GENERATION DIAGNOSTICSFOR CORONARY AND PERIPHERAL ARTERY DISEASE AND THERAPEUTICS FOR NEO-VASCULARIZATION OF VEINS, BIOMATERIAL TISSUE CONSTRUCTS TO REPLACE ARTERIES OR VEINS, AND PERCUTANEOUS PROSTHETIC VENOUS VALVES TO TREAT CHRONIC VENOUS INSUFFICIENCY. DURING THE YEAR, THE RESEARCH STAFF AT THE INSTITUTE REGULARLY PRESENTED ITS SCIENTIFIC FINDINGS TO THE PUBLIC VIA PANELS, LECTURES, PUBLICATIONS, AND OTHER SIMILAR PROGRAMS. |
| IRS990/DescribedInSection501c3Ind | 0 | true |
| IRS990/DisregardedEntityInd | 0 | false |
| IRS990/DocumentRetentionPolicyInd | 0 | true |
| IRS990/DonorAdvisedFundInd | 0 | false |
| IRS990/DonorRestrictionNetAssetsGrp/BOYAmt | 0 | 546116 |
| IRS990/DonorRestrictionNetAssetsGrp/EOYAmt | 0 | 120498 |
| IRS990/DonorRstrOrQuasiEndowmentsInd | 0 | false |
| IRS990/ElectionOfBoardMembersInd | 0 | false |
| IRS990/EmployeeCnt | 0 | 29 |
| IRS990/EmploymentTaxReturnsFiledInd | 0 | true |
| IRS990/EngagedInExcessBenefitTransInd | 0 | false |
| IRS990/ExpenseAmt | 0 | 5950963 |
| IRS990/FamilyOrBusinessRlnInd | 0 | false |
| IRS990/FederalGrantAuditPerformedInd | 0 | true |
| IRS990/FederalGrantAuditRequiredInd | 0 | true |
| IRS990/FeesForServicesAccountingGrp/ManagementAndGeneralAmt | 0 | 18100 |
| IRS990/FeesForServicesAccountingGrp/TotalAmt | 0 | 18100 |
| IRS990/FeesForServicesLegalGrp/ManagementAndGeneralAmt | 0 | 23617 |
| IRS990/FeesForServicesLegalGrp/ProgramServicesAmt | 0 | 7365 |
| IRS990/FeesForServicesLegalGrp/TotalAmt | 0 | 30982 |
| IRS990/FeesForServicesLobbyingGrp/TotalAmt | 0 | 0 |
| IRS990/FeesForServicesManagementGrp/TotalAmt | 0 | 0 |
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| IRS990/FeesForServicesProfFundraising/TotalAmt | 0 | 0 |
| IRS990/FeesForSrvcInvstMgmntFeesGrp/TotalAmt | 0 | 0 |
| IRS990/ForeignActivitiesInd | 0 | false |
| IRS990/ForeignFinancialAccountInd | 0 | false |
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| IRS990/ForeignOfficeInd | 0 | false |
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| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRltdOrgRt | 3 | 0.00 |
| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRltdOrgRt | 4 | 0.00 |
| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRltdOrgRt | 5 | 0.00 |
| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRltdOrgRt | 6 | 0.00 |
| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRltdOrgRt | 7 | 0.00 |
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| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRt | 0 | 30.00 |
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| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRt | 7 | 2.00 |
| IRS990/Form990PartVIISectionAGrp/AverageHoursPerWeekRt | 8 | 2.00 |
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| IRS990/Form990PartVIISectionAGrp/IndividualTrusteeOrDirectorInd | 1 | X |
| IRS990/Form990PartVIISectionAGrp/IndividualTrusteeOrDirectorInd | 2 | X |
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| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 1 | 31864 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 2 | 27248 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 3 | 35126 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 4 | 17971 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 5 | 17384 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 6 | 24413 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 7 | 0 |
| IRS990/Form990PartVIISectionAGrp/OtherCompensationAmt | 8 | 0 |
| IRS990/Form990PartVIISectionAGrp/PersonNm | 0 | Ghassan Kassab |
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| IRS990/Form990PartVIISectionAGrp/PersonNm | 2 | JENNY CHOY |
| IRS990/Form990PartVIISectionAGrp/PersonNm | 3 | ISMAIL QADDOURA |
| IRS990/Form990PartVIISectionAGrp/PersonNm | 4 | SANJAY SOUNDARAJAN |
| IRS990/Form990PartVIISectionAGrp/PersonNm | 5 | CHRISTOPHER MARROQUIN |
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| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 2 | 143103 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 3 | 111393 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 4 | 121194 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 5 | 107000 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 6 | 91031 |
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| IRS990/Form990PartVIISectionAGrp/ReportableCompFromOrgAmt | 8 | 0 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromRltdOrgAmt | 0 | 0 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromRltdOrgAmt | 1 | 0 |
| IRS990/Form990PartVIISectionAGrp/ReportableCompFromRltdOrgAmt | 2 | 0 |
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| IRS990/Form990PartVIISectionAGrp/TitleTxt | 0 | Chairman |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 1 | ASSC RESEARCH PROF |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 2 | RESEARCH PROFESSOR |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 3 | IT MANAGER |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 4 | ASSC RESEARCH PROF |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 5 | SOFTWARE DEVELOPER |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 6 | President & CEO |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 7 | BOARD MEMBER |
| IRS990/Form990PartVIISectionAGrp/TitleTxt | 8 | BOARD MEMBER |
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| IRS990/FormationYr | 0 | 2013 |
| IRS990/FormerOfcrEmployeesListedInd | 0 | false |
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| IRS990/FSAuditedInd | 0 | true |
| IRS990/FundraisingActivitiesInd | 0 | false |
| IRS990/GamingActivitiesInd | 0 | false |
| IRS990/GoverningBodyVotingMembersCnt | 0 | 4 |
| IRS990/GovernmentGrantsAmt | 0 | 5906916 |
| IRS990/GrantsToDomesticIndividualsGrp/TotalAmt | 0 | 0 |
| IRS990/GrantsToDomesticOrgsGrp/TotalAmt | 0 | 0 |
| IRS990/GrantsToIndividualsInd | 0 | false |
| IRS990/GrantsToOrganizationsInd | 0 | false |
| IRS990/GrantToRelatedPersonInd | 0 | false |
| IRS990/GrossReceiptsAmt | 0 | 6104330 |
| IRS990/GroupReturnForAffiliatesInd | 0 | false |
| IRS990/IncludeFIN48FootnoteInd | 0 | true |
| IRS990/IncmFromInvestBondProceedsGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/IndependentAuditFinclStmtInd | 0 | true |
| IRS990/IndependentVotingMemberCnt | 0 | 2 |
| IRS990/IndivRcvdGreaterThan100KCnt | 0 | 6 |
| IRS990/IndoorTanningServicesInd | 0 | false |
| IRS990/InfoInScheduleOPartVIInd | 0 | X |
| IRS990/InfoInScheduleOPartXIIInd | 0 | X |
| IRS990/InformationTechnologyGrp/TotalAmt | 0 | 0 |
| IRS990/InsuranceGrp/ManagementAndGeneralAmt | 0 | 3787 |
| IRS990/InsuranceGrp/ProgramServicesAmt | 0 | 28038 |
| IRS990/InsuranceGrp/TotalAmt | 0 | 31825 |
| IRS990/IntangibleAssetsGrp/EOYAmt | 0 | 0 |
| IRS990/InterestGrp/TotalAmt | 0 | 0 |
| IRS990/InventoriesForSaleOrUseGrp/BOYAmt | 0 | 10472 |
| IRS990/InventoriesForSaleOrUseGrp/EOYAmt | 0 | 9436 |
| IRS990/InvestmentIncomeGrp/ExclusionAmt | 0 | 28311 |
| IRS990/InvestmentIncomeGrp/TotalRevenueColumnAmt | 0 | 28311 |
| IRS990/InvestmentInJointVentureInd | 0 | false |
| IRS990/InvestmentsOtherSecuritiesGrp/EOYAmt | 0 | 0 |
| IRS990/InvestmentsProgramRelatedGrp/EOYAmt | 0 | 0 |
| IRS990/InvestmentsPubTradedSecGrp/EOYAmt | 0 | 0 |
| IRS990/IRPDocumentCnt | 0 | 13 |
| IRS990/IRPDocumentW2GCnt | 0 | 0 |
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| IRS990/LandBldgEquipBasisNetGrp/BOYAmt | 0 | 34415 |
| IRS990/LandBldgEquipBasisNetGrp/EOYAmt | 0 | 59364 |
| IRS990/LandBldgEquipCostOrOtherBssAmt | 0 | 1409607 |
| IRS990/LegalDomicileStateCd | 0 | CA |
| IRS990/LoanOutstandingInd | 0 | false |
| IRS990/LobbyingActivitiesInd | 0 | false |
| IRS990/LocalChaptersInd | 0 | false |
| IRS990/MaterialDiversionOrMisuseInd | 0 | false |
| IRS990/MembersOrStockholdersInd | 0 | false |
| IRS990/MethodOfAccountingAccrualInd | 0 | X |
| IRS990/MinutesOfCommitteesInd | 0 | false |
| IRS990/MinutesOfGoverningBodyInd | 0 | true |
| IRS990/MissionDesc | 0 | The Institute is a scientific research center dedicated to conducting basic and applied research to advance the understanding of human disease and the improvement of human health. The Institute fosters an innovative research environment with a multidisciplinary and collaborative approach to the discovery process - bringing together physical and life science researchers, clinicians, engineers/ and computational scientists to address the significant health care challenges of heart and vascular disease, obesity, and metabolic disorders through a multi-scale understanding of organ systems. Institute researchers have expertise in both experimental and computational disciplines. The former utilizes the experimental reductionist approach to dissect the biological system into its molecular, cellular and tissue components. The latter use a computational integrative approach to synthesize the parts using laws of physics and chemistry to understand the whole organ. The Institutes multi-discipline |
| IRS990/MoreThan5000KToIndividualsInd | 0 | false |
| IRS990/MoreThan5000KToOrgInd | 0 | false |
| IRS990/MortgNotesPyblScrdInvstPropGrp/BOYAmt | 0 | 1929086 |
| IRS990/MortgNotesPyblScrdInvstPropGrp/EOYAmt | 0 | 1875611 |
| IRS990/NetAssetsOrFundBalancesBOYAmt | 0 | -421454 |
| IRS990/NetAssetsOrFundBalancesEOYAmt | 0 | -1004509 |
| IRS990/NetGainOrLossInvestmentsGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetIncmFromFundraisingEvtGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetIncomeFromGamingGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetIncomeOrLossGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetRentalIncomeOrLossGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/NetUnrelatedBusTxblIncmAmt | 0 | 1525 |
| IRS990/NoDonorRestrictionNetAssetsGrp/BOYAmt | 0 | -967570 |
| IRS990/NoDonorRestrictionNetAssetsGrp/EOYAmt | 0 | -1125007 |
| IRS990/NondeductibleContributionsInd | 0 | false |
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| IRS990/OccupancyGrp/ProgramServicesAmt | 0 | 590944 |
| IRS990/OccupancyGrp/TotalAmt | 0 | 670760 |
| IRS990/OfficeExpensesGrp/ManagementAndGeneralAmt | 0 | 3822 |
| IRS990/OfficeExpensesGrp/ProgramServicesAmt | 0 | 28485 |
| IRS990/OfficeExpensesGrp/TotalAmt | 0 | 32307 |
| IRS990/OfficerMailingAddressInd | 0 | false |
| IRS990/OperateHospitalInd | 0 | false |
| IRS990/Organization501c3Ind | 0 | X |
| IRS990/OrganizationFollowsFASB117Ind | 0 | X |
| IRS990/OtherAssetsTotalGrp/BOYAmt | 0 | 768984 |
| IRS990/OtherAssetsTotalGrp/EOYAmt | 0 | 189537 |
| IRS990/OtherEmployeeBenefitsGrp/ManagementAndGeneralAmt | 0 | 48362 |
| IRS990/OtherEmployeeBenefitsGrp/ProgramServicesAmt | 0 | 222439 |
| IRS990/OtherEmployeeBenefitsGrp/TotalAmt | 0 | 270801 |
| IRS990/OtherExpensesGrp/Desc | 0 | CONSORTIUM |
| IRS990/OtherExpensesGrp/Desc | 1 | RESEARCH SUPPLIES & SERVICES |
| IRS990/OtherExpensesGrp/Desc | 2 | UTILITIES |
| IRS990/OtherExpensesGrp/Desc | 3 | MINOR EQUIPMENT |
| IRS990/OtherExpensesGrp/ManagementAndGeneralAmt | 0 | 18205 |
| IRS990/OtherExpensesGrp/ManagementAndGeneralAmt | 1 | 2684 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 0 | 2196810 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 1 | 253019 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 2 | 129914 |
| IRS990/OtherExpensesGrp/ProgramServicesAmt | 3 | 135116 |
| IRS990/OtherExpensesGrp/TotalAmt | 0 | 2196810 |
| IRS990/OtherExpensesGrp/TotalAmt | 1 | 253019 |
| IRS990/OtherExpensesGrp/TotalAmt | 2 | 148119 |
| IRS990/OtherExpensesGrp/TotalAmt | 3 | 137800 |
| IRS990/OtherInd | 0 | X |
| IRS990/OtherLiabilitiesGrp/BOYAmt | 0 | 779951 |
| IRS990/OtherLiabilitiesGrp/EOYAmt | 0 | 273934 |
| IRS990/OtherRevenueMiscGrp/BusinessCd | 0 | 900099 |
| IRS990/OtherRevenueMiscGrp/Desc | 0 | OTHER INCOME |
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| IRS990/OtherRevenueTotalAmt | 0 | 574 |
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| IRS990/OtherSalariesAndWagesGrp/ProgramServicesAmt | 0 | 1572830 |
| IRS990/OtherSalariesAndWagesGrp/TotalAmt | 0 | 1794814 |
| IRS990/OthNotesLoansReceivableNetGrp/EOYAmt | 0 | 0 |
| IRS990/PartialLiquidationInd | 0 | false |
| IRS990/PaymentsToAffiliatesGrp/TotalAmt | 0 | 0 |
| IRS990/PayPremiumsPrsnlBnftCntrctInd | 0 | false |
| IRS990/PayrollTaxesGrp/ManagementAndGeneralAmt | 0 | 27503 |
| IRS990/PayrollTaxesGrp/ProgramServicesAmt | 0 | 126573 |
| IRS990/PayrollTaxesGrp/TotalAmt | 0 | 154076 |
| IRS990/PensionPlanContributionsGrp/ManagementAndGeneralAmt | 0 | 32459 |
| IRS990/PensionPlanContributionsGrp/ProgramServicesAmt | 0 | 149384 |
| IRS990/PensionPlanContributionsGrp/TotalAmt | 0 | 181843 |
| IRS990/PledgesAndGrantsReceivableGrp/BOYAmt | 0 | 1126563 |
| IRS990/PledgesAndGrantsReceivableGrp/EOYAmt | 0 | 1063433 |
| IRS990/PoliticalCampaignActyInd | 0 | false |
| IRS990/PrepaidExpensesDefrdChargesGrp/BOYAmt | 0 | 16884 |
| IRS990/PrepaidExpensesDefrdChargesGrp/EOYAmt | 0 | 16430 |
| IRS990/PrincipalOfficerNm | 0 | Ghassan Kassab |
| IRS990/ProfessionalFundraisingInd | 0 | false |
| IRS990/ProgramServiceRevenueGrp/BusinessCd | 0 | 900099 |
| IRS990/ProgramServiceRevenueGrp/BusinessCd | 1 | 900099 |
| IRS990/ProgramServiceRevenueGrp/Desc | 0 | CONTRACT REVENUE |
| IRS990/ProgramServiceRevenueGrp/Desc | 1 | VENDOR SERVICES |
| IRS990/ProgramServiceRevenueGrp/TotalRevenueColumnAmt | 0 | 168529 |
| IRS990/ProgramServiceRevenueGrp/UnrelatedBusinessRevenueAmt | 0 | 168529 |
| IRS990/ProhibitedTaxShelterTransInd | 0 | false |
| IRS990/PYContributionsGrantsAmt | 0 | 5755723 |
| IRS990/PYExcessBenefitTransInd | 0 | false |
| IRS990/PYInvestmentIncomeAmt | 0 | 18383 |
| IRS990/PymtTravelEntrtnmntPubOfclGrp/TotalAmt | 0 | 0 |
| IRS990/PYOtherExpensesAmt | 0 | 4060877 |
| IRS990/PYOtherRevenueAmt | 0 | 855 |
| IRS990/PYProgramServiceRevenueAmt | 0 | 290584 |
| IRS990/PYRevenuesLessExpensesAmt | 0 | -478460 |
| IRS990/PYSalariesCompEmpBnftPaidAmt | 0 | 2483128 |
| IRS990/PYTotalExpensesAmt | 0 | 6544005 |
| IRS990/PYTotalRevenueAmt | 0 | 6065545 |
| IRS990/QuidProQuoContributionsInd | 0 | false |
| IRS990/RcvblFromDisqualifiedPrsnGrp/EOYAmt | 0 | 0 |
| IRS990/RcvFndsToPayPrsnlBnftCntrctInd | 0 | false |
| IRS990/ReceivablesFromOfficersEtcGrp/EOYAmt | 0 | 0 |
| IRS990/ReconcilationRevenueExpnssAmt | 0 | -583055 |
| IRS990/RegularMonitoringEnfrcInd | 0 | true |
| IRS990/RelatedEntityInd | 0 | false |
| IRS990/RelatedOrganizationCtrlEntInd | 0 | false |
| IRS990/ReportInvestmentsOtherSecInd | 0 | false |
| IRS990/ReportLandBuildingEquipmentInd | 0 | true |
| IRS990/ReportOtherAssetsInd | 0 | true |
| IRS990/ReportOtherLiabilitiesInd | 0 | true |
| IRS990/ReportProgramRelatedInvstInd | 0 | false |
| IRS990/RevenueAmt | 0 | 168529 |
| IRS990/RoyaltiesGrp/TotalAmt | 0 | 0 |
| IRS990/RoyaltiesRevenueGrp/TotalRevenueColumnAmt | 0 | 0 |
| IRS990/SavingsAndTempCashInvstGrp/EOYAmt | 0 | 0 |
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| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus1YearAmt | 0 | 5755723 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 3679055 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus3YearsAmt | 0 | 3707863 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus4YearsAmt | 0 | 3889272 |
| IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/TotalAmt | 0 | 22938829 |
| IRS990ScheduleA/GovtFurnSrvcFcltsVl170Grp/TotalAmt | 0 | 0 |
| IRS990ScheduleA/GrossInvestmentIncome170Grp/TotalAmt | 0 | 0 |
| IRS990ScheduleA/GrossReceiptsRltdActivitiesAmt | 0 | 158507 |
| IRS990ScheduleA/OtherIncome170Grp/TotalAmt | 0 | 0 |
| IRS990ScheduleA/PublicOrganization170Ind | 0 | X |
| IRS990ScheduleA/PublicSupportCY170Pct | 0 | 0.94870 |
| IRS990ScheduleA/PublicSupportPY170Pct | 0 | 0.93850 |
| IRS990ScheduleA/PublicSupportTotal170Amt | 0 | 21900525 |
| IRS990ScheduleA/SubstantialContributorsTotAmt | 0 | 1038304 |
| IRS990ScheduleA/TaxRevLeviedOrgnztnlBnft170Grp/TotalAmt | 0 | 0 |
| IRS990ScheduleA/ThirtyThrPctSuprtTestsCY170Ind | 0 | X |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearAmt | 0 | 5906916 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus1YearAmt | 0 | 5755723 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 3679055 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus3YearsAmt | 0 | 3707863 |
| IRS990ScheduleA/TotalCalendarYear170Grp/CurrentTaxYearMinus4YearsAmt | 0 | 3889272 |
| IRS990ScheduleA/TotalCalendarYear170Grp/TotalAmt | 0 | 22938829 |
| IRS990ScheduleA/TotalSupportAmt | 0 | 23084779 |
| IRS990ScheduleA/UnrelatedBusinessNetIncm170Grp/CurrentTaxYearMinus2YearsAmt | 0 | 38885 |
| IRS990ScheduleA/UnrelatedBusinessNetIncm170Grp/CurrentTaxYearMinus3YearsAmt | 0 | 66563 |
| IRS990ScheduleA/UnrelatedBusinessNetIncm170Grp/CurrentTaxYearMinus4YearsAmt | 0 | 40502 |
| IRS990ScheduleA/UnrelatedBusinessNetIncm170Grp/TotalAmt | 0 | 145950 |
| IRS990ScheduleB/ContributorInformationGrp/ContributorBusinessName/BusinessNameLine1 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorNum | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine1 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/AddressLine2 | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/City | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/State | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/ContributorUSAddress/ZIPCode | 0 | RESTRICTED |
| IRS990ScheduleB/ContributorInformationGrp/TotalContributionsAmt | 0 | RESTRICTED |
| IRS990/ScheduleBRequiredInd | 0 | true |
| IRS990ScheduleD/EquipmentGrp/BookValueAmt | 0 | 59364 |
| IRS990ScheduleD/EquipmentGrp/DepreciationAmt | 0 | 1350243 |
| IRS990ScheduleD/EquipmentGrp/OtherCostOrOtherBasisAmt | 0 | 1409607 |
| IRS990ScheduleD/ExpensesSubtotalAmt | 0 | 6687385 |
| IRS990ScheduleD/FootnoteTextInd | 0 | X |
| IRS990ScheduleD/OtherAssetsOrgGrp/BookValueAmt | 0 | 42785 |
| IRS990ScheduleD/OtherAssetsOrgGrp/BookValueAmt | 1 | 146752 |
| IRS990ScheduleD/OtherAssetsOrgGrp/Desc | 0 | DEPOSIT |
| IRS990ScheduleD/OtherAssetsOrgGrp/Desc | 1 | RIGHT OF USE ASSET |
| IRS990ScheduleD/OtherLiabilitiesOrgGrp/Amt | 0 | 109036 |
| IRS990ScheduleD/OtherLiabilitiesOrgGrp/Amt | 1 | 164898 |
| IRS990ScheduleD/OtherLiabilitiesOrgGrp/Desc | 0 | ACCRUED PAYROLL |
| IRS990ScheduleD/OtherLiabilitiesOrgGrp/Desc | 1 | OPERATING LEASE LIABILITY |
| IRS990ScheduleD/RevenueSubtotalAmt | 0 | 6104330 |
| IRS990ScheduleD/SupplementalInformationDetail/ExplanationTxt | 0 | The Institute is a public charity and is exempt from income taxes under Section 501(c)(3) of the Internal Revenue Code and Section 23701(d) of the California Revenue and Taxation Code. The Institute believes that it has appropriate support for any tax positions taken, and as such, does not have any uncertain tax positions that are material to the financial statements. The Institute is not a private foundation. |
| IRS990ScheduleD/SupplementalInformationDetail/FormAndLineReferenceDesc | 0 | Part X : FIN48 Footnote |
| IRS990ScheduleD/TotalBookValueLandBuildingsAmt | 0 | 59364 |
| IRS990ScheduleD/TotalBookValueOtherAssetsAmt | 0 | 189537 |
| IRS990ScheduleD/TotalExpensesPerForm990Amt | 0 | 6687385 |
| IRS990ScheduleD/TotalLiabilityAmt | 0 | 273934 |
| IRS990ScheduleD/TotalRevenuePerForm990Amt | 0 | 6104330 |
| IRS990ScheduleD/TotalRevEtcAuditedFinclStmtAmt | 0 | 6104330 |
| IRS990ScheduleD/TotExpnsEtcAuditedFinclStmtAmt | 0 | 6687385 |
| IRS990ScheduleJ/AnyNonFixedPaymentsInd | 0 | false |
| IRS990ScheduleJ/BoardOrCommitteeApprovalInd | 0 | X |
| IRS990ScheduleJ/CompBasedOnRevenueOfFlngOrgInd | 0 | false |
| IRS990ScheduleJ/CompBsdNetEarnsFlngOrgInd | 0 | false |
| IRS990ScheduleJ/CompBsdNetEarnsRltdOrgsInd | 0 | false |
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