Magee-Womens Research Institute and Foundation

“The initial draft of Form 990, which is prepared by the MWRIF Project Manager-Finance, is reviewed by the Sr. Director of Finance. It is then reviewed by a representative of MWRIF's external auditors Maher Duessel. After that, the Audit Committee, a sub-committee of the Board of Directors, reviews and provides a report to the Board. A copy of the Form 990 is provided to the full Board of Directors prior to filing with the IRS.”

“The organization has a conflict of interest policy that is driven by the classification of each individual as follows: Board members are required to sign a formal conflict of interest questionnaire annually prior to the beginning of each fiscal year for which they are a member. The forms are reviewed internally by the CEO and actual or potential conflicts are reported to the Board Chair. * Designated individuals (managers and above, and any employee holding a position of influence or trust) supporting MWRIF who are employed by UPMC are required to follow their employer mandated conflict of interest policy which includes annual electronic disclosures, as well as additional disclosures as related circumstances change. These are reviewed and monitored by the UPMC Ethics and Compliance Committee. If potential and actual conflicts are identified, a Conflict Management Plan must be developed and submitted to the Committee. Failure to disclose potential conflicts or to follow the approved conflict management plan will result in disciplinary action. * Designated individuals (all faculty, staff with administrator IV title or above and any others designated based on their responsibilities) working at MWRIF who are employees of the University of Pittsburgh are required to follow their employer mandated conflict of interest policy which includes annual electronic conflict of interest disclosures, as well as additional disclosures as related circumstances change. These are reviewed by the individual's department head and reported to University senior management as well as maintained by the Conflict of Interest Committee. Potential or actual conflicts are handled by the employees first line supervisor and a management plan developed. The plan is submitted to senior management as well as the COI committee for review. Sanctions may be applied for non-compliance with the requirements of the policy or with management plans, including a letter of reprimand, special monitoring of future work, removal from the particular project, probation, suspension, salary reduction, or initiation of steps leading to possible reduction in rank or termination of employment.”

“The (Interim) Executive Director of MWRIF is dually employed by both the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC). The (Interim) Executive Director's time is spent on medical research, their Executive Director's responsibilities, and their clinical responsibilities to take care of patients. MWRIF is financially responsible for the (Interim) Executive Director's compensation related to medical research and their Executive Director's responsibilities; MWRIF reimburses the University of Pittsburgh and UPMC for this compensation. Each of the three organizations are involved in evaluating the Executive Director's compensation taking into consideration their accomplishments, responsibilities, and comparing against AAMC (American Association of Medical Colleges) benchmarks. The initial salary as well as any subsequent adjustments are approved by senior management of the University of Pittsburgh and UPMC and by selected external members of the MWRIF Board. All paperwork regarding the process and approvals is maintained by the respective organizations. The CEO's initial salary as well as any subsequent adjustments are reviewed by both UPMC and select independent directors of the MWRIF Board, taking into consideration accomplishments, responsibilities and a review of salaries for comparable positions in the marketplace. All related paperwork is maintained by UPMC. Since 100% of the CEO's time is spent in supporting the mission of MWRIF, MWRIF is financially responsible for the entire salary and any subsequent adjustments and incentives.”

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“The Conflict of Interest Policy, governing documents, and financial statements are available at the Organization's business office located at 204 Craft Ave, Pittsburgh, PA 15213.”

“Dr. Yoel Sadovsky stepped down from his position as Executive Director of MWRIF effective June 30, 2024. He remained employed as Principal Investigator until June 30, 2025. Dr. Pamela Moalli became Interim Executive Director effective July 1st, 2024.”

“The research conducted at MWRIF occurs in a facility located at 204 Craft Avenue. UPMC owns this building, and MWRIF is renting the space from them. Since the lease agreement with UPMC is long term (30 years), for accounting purposes it has to be recorded as a liability on MWRIF's books. This is the mortgage/note payable disclosed on Line 24 of Part X. The lease agreement does not contain any terms implying that MWRIF will ever own or have the option to buy the building. The rental income disclosed in Part VIII is generated by subleases between MWRIF and several research labs that are part of the University of Pittsburgh, allowing them to occupy a portion of the space MWRIF is renting from UPMC. These particular University of Pittsburgh researchers collaborate with MWRIF researchers on a regular basis on large biomedical research projects where physical proximity facilitates the collaborative process and allows them to meet, share equipment and other resources as needed to make the collaboration more efficient and hopefully more successful. The objective in renting the space to the University of Pittsburgh is to facilitate the collaboration, not to generate profit. So, the rental income disclosed in Part VIII is sublease income that offsets a portion of MWRIF's lease expense. MWRIF has no acquisition indebtedness which would require the rental income to be disclosed as unrelated business income.”

“(and Part V, Line 2a) - MWRIF doesn't have any employees of its own. All individuals who work in support of the mission of MWRIF are employed either by the University of Pittsburgh or the University of Pittsburgh Medical Center (UPMC). MWRIF is billed by each organization for the cost of salary and fringe benefits corresponding to the effort these individuals expend in support of the MWRIF mission. MWRIF records such costs as compensation on its financial statements. Payroll taxes are filed by the employer organizations.”

“Magee-Womens Research Institute (MWRI) is one of the largest research institutes worldwide devoted exclusively to women's health research. Our mission is to advance scientific knowledge in the field of reproductive sciences and women's health; to accelerate the translation of that research into practice and improved clinical outcomes; to train the next generation of scientists in the field; to change the world's thinking on women's health and its investment in women's health research; and to expand our worldwide collaborative research. We focus on seven areas of research, including reproductive endocrinology and infertility; reproductive development; pregnancy and newborn medicine; gynecology; infectious diseases; women's cancers and women's wellness and health services.”

“Magee-Womens Research Institute (MWRI) is one of the largest research institutes worldwide devoted exclusively to reproductive sciences and women's health research. MWRI is making discoveries and advancing knowledge in many areas affecting women including: reproductive biology and development, female cancer genomics and personalized therapies, HIV immunization and prevention, fertility preservation, and pelvic floor research. Through our revolutionary 9-90TM research, we focus on how pregnancy and fetal development can affect health and disease prevention for future generations. We firmly believe that new insights into the role of early human development in defining short- and long-term health and wellness will transform our understanding of disease development, treatment and prevention for future generations. Researchers concentrate on seven key areas of discovery: reproductive endocrinology and infertility (including ovarian biology, female and male germ cell development, infertility and restoration of fertility); reproductive development (including reproductive development, stem cell biology, germ cell development and differentiation and microbiome and development); pregnancy and newborn medicine (including prenatal genetics, feto-placental development, preterm birth, preeclampsia, newborn medicine); gynecology (including family planning, benign gynecological disorders, urogynecology and pelvic floor dysfunction); infectious diseases (including HIV and vaginal microbicides, reproductive tract infections, pharmaceutics and drug delivery); women's cancers (reproductive tract cancers); and women's wellness and health services outcomes (including patient-provider communication, substance use disorders, behavioral health and alternative medicine). Considering our depth and breadth, MWRI strives to advance scientific discovery and translate the results of scientific research into knowledge pertinent to women's health. To ensure the future of women's health research, MWRI has established educational programs at all levels of academic development, including opportunities for faculty and postdoctoral scholars as well as graduate and medical students, college students and high school students. MWRI hosts the Magee-Womens Research Summit, an international conference of physicians, researchers and corporate leaders focused on women's health. The centerpiece of the summit is the award of a $1 million prize for collaborative and transformative research within the reproductive sciences. Dedicated to solving real-world problems and improving lives today and for future generations as well as to coaching the next generation of scientists, MWRI is committed to a better, healthier world in which women's health has the scientific prominence and cultural status it deserves.”