Wake Forest University Health Sciences

“Bradley clark and terry williams, officers of the filing organization, had a business relationship during the filing year. Gerald f. Roach and john m. Vann, directors of the filing organization, had a business relationship for part of the filing year.”

“Effective july 1, 2010, the governing boards of the filing organization (wfuhs), wake forest university (wfu), north carolina baptist hospital (ncbh, an entity unrelated to the wfu and wfuhs), and wake forest university baptist medical center (wfubmc) approved a medical center integration agreement (mcia) whereby an integrated academic medical center (collectively, "the medical center") was created that combined clinical care, medical education, and research activities conducted by those parties and their respective subsidiary entities, under the delegated operational management and oversight of the filing organization, itself a north carolina nonprofit corporation whose two equal members were wfu and ncbh. Effective october 9, 2020, and pursuant to a health system integration agreement among wfubmc, wfu, wfuhs, ncbh, and the charlotte-mecklenburg hospital authority (cmha, a north carolina hospital authority that operates a multi-state integrated healthcare system in the southeastern united states), the medical center and cmha became participants in a single, integrated healthcare delivery and academic system (the "atrium enterprise") managed and overseen by atrium health, inc. (atrium), a new joint operating company without members whose 16-person board of directors (the "atrium board") is comprised initially of 13 cmha designees and three medical center designees; the mcia was amended to include atrium as a third member of wfubmc and to reconstitute the wfubmc board to include 17 voting directors of whom wfu designates six, ncbh designates sixed, atrium designates three, and the wfubmc board elects two; and the medical center (including wfuhs and the wake forest university school of medicine) was established as the academic core of the enterprise responsible for its academic and research activities. Under this arrangement, each atrium enterprise participant (and its affiliates) maintains its separate legal existence and continues to own its assets and retain all power, authorities, rights and remedies necessary or appropriate to allow it to comply with its pre-existing debt instruments. Wfubmc and cmha delegated authority to atrium to manage and oversee their activities and operations, subject to the authority of the university, wfuhs, and wfubmc over academic and research matters, the exercise of certain reserved powers, and the carrying out of certain responsibilities by the wfubmc board and the cmha board of commissioners. The reserved powers of each atrium enterprise participant include the power to approve a change in its fundamental business or mission and, subject to the atrium board's approval, to develop its strategic plans (which will be generally consistent with those of the entire enterprise) and its capital and operating budgets. The wake forest school of medicine continues as an academic unit owned and operated by the university through wfuhs. The executive vice president for health affairs is an officer of the university, and concurrently holds appointments as the chief executive officer and the chief academic officer (cao) of wfubmc and the enterprise. The cao reports exclusively to the university president on school of medicine-related academic matters and the president must consent to the appointment of the dean of the school of medicine by the cao. The university, generally through the school of medicine, continues to be responsible for, and have the authority regarding, all academic functions of the school of medicine. As such, the university continues to hold and exercise, at minimum, the degree of academic and academically-related administrative authority over wfubmc, the school of medicine, and wfuhs that the university exercised prior to the creation of the enterprise. In addition to forming a unified health system, a second campus of the school of medicine will be established in charlotte, north carolina, which will be affiliated with atrium and is scheduled to open to first-year m.d. Students in com”

“Wake forest university is the sole member of the filing organization.”

“The directors of the filing organization are elected by the board of trustees of its sole member, wake forest university.”

“Decisions of the filing organization's governing body which require approval by the organization's sole member, wake forest university, include amendments to certain fundamental documents (articles of incorporation and bylaws); academic appointment of faculty, grant of tenure and dismissal; and dissolution. The disposition of certain real property of the filing organization is subject to the approval of the chair and vice chair of the board of wfubmc. Notwithstanding the filing organization's participation in the health system integration among its parent entity (wake forest university), wfubmc, ncbh, and cmha described in the narrative response on schedule o to the explanation regarding part vi, section a, line 3, whereby the filing organization became a part of a single, integrated healthcare delivery and academic system (the "atrium enterprise") managed and overseen by atrium health, inc., significant authority over governance decisions regarding the academic operations of the wake forest university school of medicine and its programs and faculty was retained in the filing organization and its parent as summarized in that narrative response.”

“The filing organization's board of directors receives a copy of the form 990 with sufficient time to permit review and comment prior to its filing. If modifications are required following such review and comment, the revised form 990 is redistributed to all board members prior to its filing with the irs, along with a report noting the modifications.”

“The organization requires officers and key employees to annually review the conflict of interest policy and determine any potential conflicts of interest. Any potential conflicts noted in the questionnaire are reviewed by a standing committee for appropriate resolution. All members of the board of directors are required to determine and report annually, and as they arise, any potential conflicts of interest to the secretary of the board of directors. The resolution of potential and actual conflicts is subject to the approval of the chair of the board and is reported to the chair of the audit & compliance committee of the board of directors.”

“Through an amendment of the filing organization's bylaws, a senior executive compensation committee (the "committee") of the filing organization's board was created; it is comprised of the members of the advocate health, inc. Compensation, benefits, and equity committee. The compensation, benefits, and equity committee of the advocate health, inc. Board of directors has authority as the wfubmc board delegates to it, for the review and approval of senior executive compensation, including senior executive incentive plans. No member of the committee is an employee of the market region. The committee relies upon an external, independent compensation consultant experienced in healthcare to provide the committee with compensation comparability data for new executive position appointments and for compensation reviews for existing executives. The consultant, which is retained directly by the committee, provides third-party information and evaluates the competitiveness and reasonableness of executive compensation and benefits programs in relation to market practices for similarly situated healthcare organizations. The committee makes its decisions with respect to executive compensation in accordance with market region policies, irs regulations, and standard corporate governance practices. Such policies include adherence to executive compensation philosophy and review processes; processes ensuring committee member and compensation consultant independence; use of valid market comparisons of data from healthcare organizations of similar size, structure, and complexity and establishment of the rebuttable presumption of reasonableness, per irs guidelines. Minutes of the deliberations of the committee are maintained in the advocate health, inc. Legal department.”

“The organization's articles of incorporation are available to the public on request and are available on the website of the north carolina secretary of state. The organization's bylaws are not published, but provisions from the bylaws are included as necessary in the organization's policies, and are attached to the form 1023 filed for the organization with the irs, which is publicly available. The conflict of interest policy and financial statements are available to the public on request.”

“A medical center integration agreement (mcia) was originally entered into in 2010 among four parties: wake forest university (wfu), wake forest university health sciences (wfuhs), wake forest university baptist medical center (wfubmc), and north carolina baptist hospital (ncbh). Pursuant to the terms of the original mcia, the operation of wfuhs and ncbh, and all of the respective subsidiaries of each, is delegated to wfubmc. Additionally, the corporate officers of wfubmc generally serve as the corporate officers of wfuhs and ncbh. The mcia was revised and restated in 2020 to delegate oversight and management authority over wfubmc to atrium health, inc. (ahi). Certain directors and/or corporate officers of wfuhs, ncbh, & wfubmc also serve as directors or corporate officers of ahi and/or of wfu. Wfu and wfubmc are organizations related to the filing organization. Ncbh and ahi are organizations unrelated to the filing organization. Thus, certain directors and officers of the filing organization devote hours to related organizations (wfu and wfubmc) and their subsidiaries and/or to unrelated organizations (ncbh and ahi) and their subsidiaries.”

“Wake forest university health sciences (wfuhs) is an integral part of atrium health wake forest baptist (ahwfb), a preeminent academic health system of the highest quality with balanced excellence in patient care, research, and education that promotes better health for all through collaboration and innovation. The following paragraphs are provided to explain the relationship of the filing organization with other organizations which together comprise "atrium health wake forest baptist," the name not of any one corporate entity, but used generically to describe a large group of mostly 501(c)(3) organizations performing various academic health system activities in northwest north carolina, including patient care, medical research, technology transfer, and medical education. Wake forest university baptist medical center (wfubmc) is a north carolina nonprofit corporation whose three members are wake forest university (wfu), north carolina baptist hospital (ncbh) and atrium health, inc. (each of which is a north carolina nonprofit corporation exempt from tax under irc section 501(c)(3)). Pursuant to an agreement, initially entered into on july 1, 2010, and subsequently amended and restated multiple times including, effective october 9, 2020, and as amended february 24, 2021 to add atrium health, inc. As a party thereto (initially known as the medical center integration agreement and now as the amended and restated medical center integration agreement or the mcia), wfubmc is the overall umbrella operating entity of the atrium health system's northwest north carolina component entities. North carolina baptist hospital and wake forest university health sciences and their respective subsidiaries are operated, pursuant to delegations in the mcia, by wfubmc as "atrium health wake forest baptist." the filing organization, in turn, operates the wake forest university school of medicine. On october 9, 2020, the charlotte mecklenburg hospital authority (cmha), wake forest university, ncbh, wfuhs, and the filing organization formed a single, integrated health care delivery system through a joint operating company, atrium health, inc. (a north carolina nonprofit corporation previously organized by cmha and wfubmc). Through this health care system integration and pursuant to an agreement known as the "enterprise agreement," atrium health, inc. Manages and oversees the business, facilities, services, personnel, and activities of cmha and wfubmc (collectively the "atrium enterprise"). The atrium enterprise encompasses 40 hospitals, including four children's campuses, and more than 500 care sites across north carolina, south carolina, georgia, and virginia. Note that the following narrative includes in some of its descriptions the additional operations of the atrium enterprise through davie medical center (trading as atrium health wake forest baptist davie medical center), high point regional health (trading as atrium health wake forest baptist high point medical center), lexington medical center (trading as atrium health wake forest baptist lexington medical center), wrmc hospital operating corporation (trading as atrium health wake forest baptist wilkes medical center), and wake forest health network llc, the sole member of each of which is wfubmc, as well as organizations related to (or unrelated but affiliated with) wfubmc, in order to provide a more complete picture of the filing organization's role in the integrated health system's comprehensive activities. Atrium health wake forest baptist is northwest north carolina's sole academic learning health system, bringing to the region the resources of one of america's top hospitals and innovative research centers and a premier medical school, located on three campuses. It operates the wake forest university school of medicine, which has a faculty of over 3,000, including physicians and basic scientists with full or adjunct appointments. In addition to this faculty, the wake forest health network h”

“Research awards received by wfuhs (principally as wake forest university school of medicine) during 2024 totaled just over $422.9 million, including $262 million from federal sources (including the national institutes of health (nih)and the u.s. Department of defense), $114.9 from nonprofit and state sources, and $45.9 million from industry sources. Significant research grants announced during the period included: - a $28.2 million grant from the national institutes of health to accelerate translation of scientific discoveries. The seven-year award is the wake forest university school of medicine's clinical and translational sciences institute's (ctsi) third clinical and translational science award (ctsa), which is designed to accelerate the translation of research discoveries to improve patient care. - a $27 million grant from the national institute on aging (nia), part of the national institutes of health (nih), to renew funding for mesa-mind, an ancillary study to the multi-ethnic study of atherosclerosis (mesa). - a $4.5 million grant from the department of defense to study cervical spine injuries in military personnel. - a $3.4 million awarded to the wake forest university school of medicine, advocate health, and vysnova partners the u.s. Centers for disease control and prevention (cdc). The purpose of the four-year contract is to study hiv, mpox, and other sexually transmitted infections (stis). This project is part of the cdc's sexually transmitted infections impact research consortium. - a $3.4 million, five-year grant from the national institute on aging, part of the national institutes of health, to study medical misinformation. - a $3.3 million grant from the national institute of diabetes and digestive and kidney diseases, part of the national institutes of health, to study and develop a treatment for primary hyperoxaluria (ph). This rare genetic disorder causes kidney stones and other serious health problems. - a $3.2 million grant to study financial hardship intervention in adolescent and young adult cancer survivors. The five-year grant was awarded by the national cancer institute (nci), part of the national institutes of health, to test a multilevel intervention in community-based oncology practices in the nci's community oncology research program (ncorp), a national network that brings cancer clinical trials and cancer delivery studies to communities. - a $3.2 million grant from the national center of complementary and integrative health, part of the national institutes of health (nih), to study the effectiveness of non-pharmacological treatments for migraine. - a $1.5 million grant from the kate b. Reynolds charitable trust for the "reimagining health and wellbeing by mothers for our babies, families and communities" project to reduce disparities in birth and postpartum outcomes for black and latinx communities in forsyth county. The wake forest university school of medicine will partner with local non-profit action$equity to support community-led efforts to eliminate disparities in outcomes for moms and babies. - a $1.5 million grant from the national institute of arthritis and musculoskeletal and skin diseases, part of the national institutes of health (nih), to study bone microarchitecture in patients following bariatric surgery. The wake forest university school of medicine will partner with virginia tech to add a virtual biopsy that uses an innovative technique called high-resolution peripheral quantitative computed tomography (hr-pqct) to an ongoing randomized controlled trial. - three grants totaling $1.3 million from the duke endowment to support programs promoting the health and activity of older adults at home, addressing food insecurity, and engaging students in health care careers. ---patient integrated assessment (patina), a patient-centered platform to support older adults' health and activity at home, received $555,000 to support this project's efforts to promote coordinated care for at-risk ol”

“1. Clinical services atrium health wake forest baptist is nationally recognized for clinical excellence and internationally known for pioneering research and clinical innovation. It offers expertise in more than 100 areas of medicine, encompassing comprehensive preventive and highly specialized care for all ages. Atrium health wake forest baptist's network includes the 167-bed comprehensive cancer center and the 144-bed brenner children's hospital, both of which are on the atrium health wake forest baptist medical center campus in winston-salem, as well as community hospitals in davidson, davie, guilford, and wilkes counties. Brenner children's hospital also includes the dale and karen sisel neonatal intensive care unit, with 51 all-private rooms. Across its service area of northwest north carolina and southwest virginia, atrium health wake forest baptist has seven emergency departments; 11 urgent care locations; 458 physician practices, including primary care and specialty clinics; 28 cancer care locations; and three ambulatory surgery centers. As of december 31, 2024, atrium health wake forest baptist employed 22,478 people, including over 2,000 physicians, 2,700 active medical staff; 3,200 providers aligned through its accountable care organization and clinically integrated network; 1,200 advanced practice providers; and 4,500 nurses. Atrium health wake forest baptist continues to invest in the communities it serves through new and expanded facilities and services. In 2024, the health system opened four new locations in greensboro, north carolina, including a medical office building, an urgent care and family medicine clinic and pediatric clinics. It expanded services in east winston-salem into a historically underserved area and renamed the building the kennedy-hopkins medical building, in memory of two black medical pioneers. Ahwfb broke ground on an outpatient surgery center in winston-salem, north carolina and a multispecialty medical office building and outpatient surgery center in greensboro, north carolina, totaling more than 164,000 square feet of space. For the 2024 calendar year, the atrium health wake forest baptist system had 90,522 acute care bedded discharges; 247,093 emergency department visits; 2,657,461 physician office visits; and 150,789 urgent care visits in 2024, atrium health wake forest baptist became the first in advocate health to give lecanemab the first fda-approved drug for alzheimer's disease in more than 20 years to a patient. This milestone positions ahwfb as a leader in innovative care and builds on its reputation for bridging academic research with care. Atrium health wake forest baptist became the first and only health system in the carolinas to begin using the only fda-cleared robotic-assisted cochlear implant technology. Cochlear implants can be described as "bionic ears" that are implanted into the inner ear of patients 9 months and older who need advanced help beyond hearing aids to restore hearing. Cochlear implants provide direct electrical stimulation, through the ear, to the hearing centers of the brain. The robotic-assisted insertion system is currently indicated for patients 12 years of age and older who qualify for a cochlear implant. Being at the forefront of technology, atrium health wake forest baptist is one of the select centers to offer the technology with the closest other centers in new jersey, philadelphia and florida. Highlighting its nationally recognized achievements in patient safety and quality, atrium health wake forest baptist davie medical center received its sixth consecutive a grade from the leapfrog group. 2. Outreach atrium health wake forest baptist continues a broad-based effort to reach underserved populations across its service area, which is reflected in its annual community benefits report. For tax year ended december 31, 2024, atrium health wake forest baptist reported it provided community benefits valued at $945 million, including $105 million in bad”

“For calendar year 2023, atrium health wake forest baptist provided $148.9 million in education funding for medical students and other health care professionals and in research funding not covered by outside sources. Such investments support the training of hundreds of students. As of december 31, 2023, those included 576 md students, 780 physician residents and fellows, 397 graduate students, 167 physician assistant students, 93 students pursuing the doctor of nursing practice degree (28 in the online program and 65 pursuing the dual dnp and nurse anesthesia degree), and 19 pastoral care chaplain residents (6), fellows (2), and interns (11). The traditional nurse anesthesia master's degree program graduated its final class of students in august 2023, and all cohorts moving forward are pursuing the dual dnp-nurse anesthesia degree. In addition, 142 students were enrolled in the virginia tech-wake forest university school of biomedical engineering and sciences, with 70 of those on the wake forest university campus. During the 2022-23 academic year, the northwest area health education center, part of the wake forest university school of medicine, offered 2,415 continuing professional development activities for practicing health care professionals that drew 50,781 total participants from throughout the region.”

“Equity method affiliates -69,784,859. Actuarial gain 2,556,037.”