Civic Intelligence

Xenobe Research Institute

EIN 20-1624945 • 501(c)3 • San Diego, CA

Profile

The Xenobe Research Institute conducts research on natural and synthetic small molecule therapeutics with the ultimate goal of discovering and ultimately translating new materials for clinical trials.

PO Box 3052San Diego, CA 92163-1052

www.xenobe.org

Siviq Scores

Precomputed percentiles relative to similar nonprofits. These scores are descriptive rather than judgmental.

Liabilities / Assets

60th percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2025

Liabilities / Revenue

62nd percentile

0.00x

Tied with the lowest-debt nonprofits in its peer group.

501(c)3 • <$500k nonprofits • Source year 2025

Net Margin

78th percentile

25%

Higher net margin than 78% of similar nonprofits.

501(c)3 • <$500k nonprofits • Source year 2025

Top Officer Pay

93rd percentile

$44,352

Higher top officer pay than 93% of similar nonprofits.

Top officer pay equals 25.4% of source-year revenue.

501(c)3 • <$500k nonprofits • Source year 2025

Asset Growth

28th percentile

-28%

Faster asset growth than 28% of similar nonprofits.

501(c)3 • <$500k nonprofits • Annualized from 2024 to 2025

Revenue Growth

36th percentile

-16%

Faster revenue growth than 36% of similar nonprofits.

501(c)3 • <$500k nonprofits • Annualized from 2024 to 2025

Balance Sheet
Liabilities / Assets60th percentile

Assets

Down

$271,239

Down $104,812 (-28%) from 2024

Liabilities

Flat

$0

Flat from 2024

Net Assets

Down

$271,239

Down $104,812 (-28%) from 2024

Operations
Liabilities / Revenue62nd percentileNet Margin78th percentile

Revenue

Down

$174,939

Down $34,326 (-16%) from 2024

Expenses

Down

$131,801

Down $15,699 (-11%) from 2024

Net Income

Down

$43,138

Down $18,627 (-30%) from 2024

Trend Graphs

Balance Sheet Trend

Asset Growth28th percentile

Grouped bars show assets, liabilities, and net assets across loaded filings.

$400K$300K$200K$100K$0Assets 2012: $98,990Liabilities 2012: $02012Assets 2013: $97,554Liabilities 2013: $02013Assets 2014: $96,820Liabilities 2014: $02014Assets 2015: $98,395Liabilities 2015: $02015Assets 2016: $97,188Liabilities 2016: $02016Assets 2017: $98,228Liabilities 2017: $02017Assets 2018: $111,472Liabilities 2018: $02018Assets 2019: $98,104Liabilities 2019: $02019Assets 2020: $115,522Liabilities 2020: $02020Assets 2021: $115,117Liabilities 2021: $02021Assets 2022: $116,807Liabilities 2022: $0Net Assets 2022: $116,8072022Assets 2023: $314,286Liabilities 2023: $0Net Assets 2023: $314,2862023Assets 2024: $376,051Liabilities 2024: $0Net Assets 2024: $376,0512024Assets 2025: $271,239Liabilities 2025: $0Net Assets 2025: $271,2392025

Highlighted filing

2025

Assets$271,239
Liabilities$0
Net Assets$271,239
Open 2025 Filing

Operations Trend

Revenue Growth36th percentile

Revenue, expenses, and net income by year, with the latest filing highlighted.

$400K$300K$200K$100K$0-$100KRevenue 2012: $20,358Expenses 2012: $18,430Net Income 2012: $1,9282012Revenue 2013: $23,970Expenses 2013: $25,405Net Income 2013: -$1,4352013Revenue 2014: $26,280Expenses 2014: $27,014Net Income 2014: -$7342014Revenue 2015: $36,937Expenses 2015: $35,362Net Income 2015: $1,5752015Revenue 2016: $35,741Expenses 2016: $36,948Net Income 2016: -$1,2072016Revenue 2017: $37,880Expenses 2017: $36,840Net Income 2017: $1,0402017Revenue 2018: $32,713Expenses 2018: $20,151Net Income 2018: $12,5622018Revenue 2019: $2,860Expenses 2019: $16,228Net Income 2019: -$13,3682019Revenue 2020: $30,300Expenses 2020: $12,581Net Income 2020: $17,7192020Revenue 2021: $78,327Expenses 2021: $78,732Net Income 2021: -$4052021Revenue 2022: $77,500Expenses 2022: $75,810Net Income 2022: $1,6902022Revenue 2023: $352,250Expenses 2023: $154,772Net Income 2023: $197,4782023Revenue 2024: $209,265Expenses 2024: $147,500Net Income 2024: $61,7652024Revenue 2025: $174,939Expenses 2025: $131,801Net Income 2025: $43,1382025

Highlighted filing

2025

Revenue$174,939
Expenses$131,801
Net Income$43,138
Open 2025 Filing

Filings

Most recent year

2025 • Form 990Detailed filing. Detailed filing data is available for this year.

Open filing
Assets
$271,239
Liabilities
$0
Net assets
$271,239
Revenue
$174,939
Expenses
$131,801
Net income
$43,138
Balance SheetOperations
YearAssetsLiabilitiesNet AssetsRevenueExpensesNet Income
2025Detailed filing. Detailed filing data is available for this year.$2.71$0.00$2.71$1.75$1.32$0.43
2024Detailed filing. Detailed filing data is available for this year.$3.76$0.00$3.76$2.09$1.48$0.62
2023Detailed filing. Detailed filing data is available for this year.$3.14$0.00$3.14$3.52$1.55$1.97
2022Detailed filing. Detailed filing data is available for this year.$1.17$0.00$1.17$0.78$0.76$0.02
2021Summary only. Only limited summary data is available for this year.$1.15$0.00$0.78$0.79$0.00
2020Summary only. Only limited summary data is available for this year.$1.16$0.00$0.30$0.13$0.18
2019Summary only. Only limited summary data is available for this year.$0.98$0.00$0.03$0.16$0.13
2018Summary only. Only limited summary data is available for this year.$1.11$0.00$0.33$0.20$0.13
2017Summary only. Only limited summary data is available for this year.$0.98$0.00$0.38$0.37$0.01
2016Summary only. Only limited summary data is available for this year.$0.97$0.00$0.36$0.37$0.01
2015Summary only. Only limited summary data is available for this year.$0.98$0.00$0.37$0.35$0.02
2014Summary only. Only limited summary data is available for this year.$0.97$0.00$0.26$0.27$0.01
2013Summary only. Only limited summary data is available for this year.$0.98$0.00$0.24$0.25$0.01
2012Summary only. Only limited summary data is available for this year.$0.99$0.00$0.20$0.18$0.02
Latest Filing Detail
Jump To
Filing Snapshot
Filing Period
Jul 1, 2024 to Jun 30, 2025
Signed
Oct 14, 2025
Return Version
2024v5.0
Gross Receipts
$174,939
Mission and Program Overview

Mission

Scientific Research - Drug Discovery

Scientific Research. The Xenobe Research Institute conducts research on natural and synthetic small molecule therapeutics with the ultimate goal of discovering and ultimately translating new materials for clinical trials.

Balance Sheet Detail
LineBeginningEndChange
Assets
Cash and Non-Interest-Bearing Accounts$131,426$174,564▲ $43,138
Inventories for Sale or Use$96,675$96,675→ $0
Savings and Temporary Cash Investments$0$0→ $0
Accounts Receivable$0$0→ $0
Other Notes and Loans Receivable, Net$0$0→ $0
Pledges and Grants Receivable$0$0→ $0
Receivable From Disqualified Prsn$0$0→ $0
Receivables From Officers Etc$0$0→ $0
Investments Other Securities$0$0→ $0
Investments Program Related$0$0→ $0
Investments in Publicly Traded Securities$0$0→ $0
Intangible Assets$0$0→ $0
Loans From Officers Directors$0$0→ $0
Prepaid Expenses and Deferred Charges$0$0→ $0
Total Assets$228,101$271,239▲ $43,138
Other Assets Total$0$0→ $0
Liabilities
Accounts Payable and Accrued Expenses$0$0→ $0
Grants Payable$0$0→ $0
Mortgage Notes Payable Secured by Investment Property$0$0→ $0
Unsecured Notes Loans Payable$0$0→ $0
Other Liabilities$0--
Deferred Revenue$0$0→ $0
Escrow Account Liability$0$0→ $0
Tax Exempt Bond Liabilities$0$0→ $0
Total Liabilities$0$0→ $0
Net Assets / Fund Balance
Net Assets Without Donor Restrictions$228,101$271,239▲ $43,138
Net Assets With Donor Restrictions$0$0→ $0
Total Net Assets Fund Balance$228,101$271,239▲ $43,138
Total Liabilities and Net Assets / Fund Balance$228,101$271,239▲ $43,138
Compensation and Service Providers
Top Officer Pay93rd percentile

Employees

NameTitleFull / Part TimeBaseTotal
James J La ClairPresidentPT$44,352$44,352

Board Members and Trustees

NameTitle
Manfred AuerDirector
Revenue and Support

Revenue Composition

Contributions and Grants
$174,939
Program Service Revenue
$0
Investment Income
$0
Other Revenue
$0
All Other Contributions
$26,989
Change in Net Assets
$43,138
Expenses and Functional Allocation

Major Expense Lines

Line ItemAmount
Salaries, Compensation, and Employee Benefits$66,600
Other Expenses$65,201
Grants and Similar Amounts Paid$0
Professional Fundraising Fees$0
Total Fundraising Expense$0

Functional Expense Allocation

Line ItemProgramManagementFundraisingTotal
Current Officers, Directors, Trustees, and Key Employees$44,352$0$0$44,352
Payroll Taxes$22,248$0$0$22,248
Travel$14,728$0$0$14,728
Conferences and Meetings$12,530$0$0$12,530
Office Expenses$3,785$0$0$3,785
Total Functional Expenses$131,801$0$0$131,801
Fundraising, Events, and Gaming
Fundraising activities
No
Gaming activities
No
Professional fundraiser used
No

Fundraising and Gaming Totals

Line ItemAmount
Fundraising Direct Expenses$0
Fundraising Gross Income$0
Gaming Direct Expenses$0
Gaming Gross Income$0
Professional Fundraising Fees$0
Political and Lobbying Activity
Political campaign activity
No
Lobbying activity
No
Subject to proxy tax
No
Insider Transactions and Loans

Loans and Receivables

Line ItemBeginningEndChange
Loans from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Receivables from Disqualified Persons$0$0→ $0
Receivables from Officers, Directors, Trustees, and Key Employees$0$0→ $0
Governance and Compliance

Governance Checklist

Compiled or reviewed by an accountant
No
Annual disclosure for covered persons
Yes
Backup withholding compliance
Yes
Business relationship with 35% controlled entity
No
Business relationship with family members
No
Business relationship with organization members
No
Material changes to governing documents
No
Compensation from other sources disclosed
No
CEO compensation reviewed
No
Other officer compensation reviewed
No
Conflict-of-interest policy
Yes
Audited financial statements prepared
No
Key decisions subject to board approval
No
Management duties delegated
No

Governance Explanations

Form 990, Part VI, Section B, Line 11B

“Copies are sent to all members of the organization”

Form 990, Part VI, Section B, Line 12C

“Yes our documents are shared with the NIH and made public on our website”

Form 990, Part VI, Section C, Line 19

“Copies of our governance, conflict of interest, ORI research misconduct documents are available by request by email to James J La Clair ([email protected]) and are annually reviewed by the National Institutes of Health. Copies are filed and stored with the National Institutes of Health.”

Filing and Contact Details

Filer

Filer Name
Xenobe Research Institute
EIN
20-1624945
Phone
8584013083
Address
PO Box 3052, San Diego, CA 92163-1052

Signing Officer

Name
James La Clair
Title
President
Phone
8584013083
Signed
2025-10-14

Organization Details

Principal Officer
James J La Clair
Formed
2004
Legal Domicile
CA
Voting Board Members
2
Independent Board Members
0
Employees
1
Volunteers
0
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IRS990/NoDonorRestrictionNetAssetsGrp/EOYAmt0271239
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IRS990/OfficeExpensesGrp/ManagementAndGeneralAmt00
IRS990/OfficeExpensesGrp/ProgramServicesAmt03785
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IRS990/OtherExpensesGrp/FundraisingAmt10
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IRS990/OthNotesLoansReceivableNetGrp/EOYAmt00
IRS990/OwnWebsiteInd0X
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IRS990/PrincipalOfficerNm0James J La Clair
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IRS990/ProgSrvcAccomActy2Grp/ExpenseAmt026889
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IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus2YearsAmt0352250
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus3YearsAmt077500
IRS990ScheduleA/GiftsGrantsContriRcvd170Grp/CurrentTaxYearMinus4YearsAmt077000
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