Civic Intelligence

Karyopharm Therapeutics Inc.

Plan context: Karyopharm Therapeutics Inc. 401(K) Plan

EIN 26-3931704 • Newton, MA • 25 filings • 4 plans

85 Wells Avenue, Suite 2Newton, MA 02459
Current Snapshot

Latest Year

2025

2025 Participants

226

2025 Assets

$55,627,157

2025 Contributions

$9,624,780

Historical Graphs

Total Assets Over Time

Aggregate end-of-year assets by filing year, excluding zero-asset years

$55,627,157$27,813,579$0201120182024YearValue
$55,627,157Latest year 2024

Participants Over Time

Largest reported end-of-year plan headcount by filing year, used to avoid double-counting participants across overlapping plans

4102050201120182025YearValue
226Latest year 2025

Company Timeline

Year summaries and individual filings are combined here so you can stay in one place while moving across years and plan filings.

Year / FilingFilingsParticipantsAssetsContributionsContrib./Participant
20251226$0$0-
Karyopharm Therapeutics Inc. Employee Benefits Plan-226---
20242285$55,627,157$9,624,780$33,771iApproximate average salary by contribution assumption: employee only about $844,279 at 4% or $562,853 at 6%; with 50% employer match about $562,853 at 4% or $375,235 at 6%; with 100% employer match about $422,139 at 4% or $281,426 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-284$55,627,157$9,624,780$33,890iApproximate average salary by contribution assumption: employee only about $847,252 at 4% or $564,835 at 6%; with 50% employer match about $564,835 at 4% or $376,556 at 6%; with 100% employer match about $423,626 at 4% or $282,417 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-285---
20232410$46,052,253$11,512,443$28,079iApproximate average salary by contribution assumption: employee only about $701,978 at 4% or $467,985 at 6%; with 50% employer match about $467,985 at 4% or $311,990 at 6%; with 100% employer match about $350,989 at 4% or $233,993 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-308$46,052,253$11,512,443$37,378iApproximate average salary by contribution assumption: employee only about $934,452 at 4% or $622,968 at 6%; with 50% employer match about $622,968 at 4% or $415,312 at 6%; with 100% employer match about $467,226 at 4% or $311,484 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-410---
20222401$36,042,620$10,339,877$25,785iApproximate average salary by contribution assumption: employee only about $644,631 at 4% or $429,754 at 6%; with 50% employer match about $429,754 at 4% or $286,503 at 6%; with 100% employer match about $322,315 at 4% or $214,877 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-401$36,042,620$10,339,877$25,785iApproximate average salary by contribution assumption: employee only about $644,631 at 4% or $429,754 at 6%; with 50% employer match about $429,754 at 4% or $286,503 at 6%; with 100% employer match about $322,315 at 4% or $214,877 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-398---
20212405$38,958,602$12,649,213$31,233iApproximate average salary by contribution assumption: employee only about $780,816 at 4% or $520,544 at 6%; with 50% employer match about $520,544 at 4% or $347,029 at 6%; with 100% employer match about $390,408 at 4% or $260,272 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-405$38,958,602$12,649,213$31,233iApproximate average salary by contribution assumption: employee only about $780,816 at 4% or $520,544 at 6%; with 50% employer match about $520,544 at 4% or $347,029 at 6%; with 100% employer match about $390,408 at 4% or $260,272 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-348---
20202379$26,482,418$8,066,097$21,283iApproximate average salary by contribution assumption: employee only about $532,064 at 4% or $354,710 at 6%; with 50% employer match about $354,710 at 4% or $236,473 at 6%; with 100% employer match about $266,032 at 4% or $177,355 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-379$26,482,418$8,066,097$21,283iApproximate average salary by contribution assumption: employee only about $532,064 at 4% or $354,710 at 6%; with 50% employer match about $354,710 at 4% or $236,473 at 6%; with 100% employer match about $266,032 at 4% or $177,355 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-323---
20192354$16,684,641$7,760,009$21,921iApproximate average salary by contribution assumption: employee only about $548,023 at 4% or $365,349 at 6%; with 50% employer match about $365,349 at 4% or $243,566 at 6%; with 100% employer match about $274,012 at 4% or $182,674 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-316$16,684,641$7,760,009$24,557iApproximate average salary by contribution assumption: employee only about $613,925 at 4% or $409,283 at 6%; with 50% employer match about $409,283 at 4% or $272,855 at 6%; with 100% employer match about $306,962 at 4% or $204,642 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-354---
20182255$8,565,688$3,793,407$14,876iApproximate average salary by contribution assumption: employee only about $371,903 at 4% or $247,935 at 6%; with 50% employer match about $247,935 at 4% or $165,290 at 6%; with 100% employer match about $185,951 at 4% or $123,968 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-255$8,565,688$3,793,407$14,876iApproximate average salary by contribution assumption: employee only about $371,903 at 4% or $247,935 at 6%; with 50% employer match about $247,935 at 4% or $165,290 at 6%; with 100% employer match about $185,951 at 4% or $123,968 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-239---
20172147$6,572,747$2,024,120$13,770iApproximate average salary by contribution assumption: employee only about $344,238 at 4% or $229,492 at 6%; with 50% employer match about $229,492 at 4% or $152,995 at 6%; with 100% employer match about $172,119 at 4% or $114,746 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-147$6,572,747$2,024,120$13,770iApproximate average salary by contribution assumption: employee only about $344,238 at 4% or $229,492 at 6%; with 50% employer match about $229,492 at 4% or $152,995 at 6%; with 100% employer match about $172,119 at 4% or $114,746 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-146---
20162136$4,450,273$1,582,845$11,639iApproximate average salary by contribution assumption: employee only about $290,964 at 4% or $193,976 at 6%; with 50% employer match about $193,976 at 4% or $129,317 at 6%; with 100% employer match about $145,482 at 4% or $96,988 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-110$4,450,273$1,582,845$14,390iApproximate average salary by contribution assumption: employee only about $359,738 at 4% or $239,825 at 6%; with 50% employer match about $239,825 at 4% or $159,883 at 6%; with 100% employer match about $179,869 at 4% or $119,913 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-136---
20152100$2,718,853$1,319,053$13,191iApproximate average salary by contribution assumption: employee only about $329,763 at 4% or $219,842 at 6%; with 50% employer match about $219,842 at 4% or $146,561 at 6%; with 100% employer match about $164,882 at 4% or $109,921 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-86$2,718,853$1,319,053$15,338iApproximate average salary by contribution assumption: employee only about $383,446 at 4% or $255,630 at 6%; with 50% employer match about $255,630 at 4% or $170,420 at 6%; with 100% employer match about $191,723 at 4% or $127,815 at 6%.
Karyopharm Therapeutics Inc. Employee Benefits Plan-100---
2014153$1,647,772$798,295$15,062iApproximate average salary by contribution assumption: employee only about $376,554 at 4% or $251,036 at 6%; with 50% employer match about $251,036 at 4% or $167,357 at 6%; with 100% employer match about $188,277 at 4% or $125,518 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-53$1,647,772$798,295$15,062iApproximate average salary by contribution assumption: employee only about $376,554 at 4% or $251,036 at 6%; with 50% employer match about $251,036 at 4% or $167,357 at 6%; with 100% employer match about $188,277 at 4% or $125,518 at 6%.
2013125$808,313$318,343$12,734iApproximate average salary by contribution assumption: employee only about $318,343 at 4% or $212,229 at 6%; with 50% employer match about $212,229 at 4% or $141,486 at 6%; with 100% employer match about $159,172 at 4% or $106,114 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-25$808,313$318,343$12,734iApproximate average salary by contribution assumption: employee only about $318,343 at 4% or $212,229 at 6%; with 50% employer match about $212,229 at 4% or $141,486 at 6%; with 100% employer match about $159,172 at 4% or $106,114 at 6%.
2012120$636,509$404,194$20,210iApproximate average salary by contribution assumption: employee only about $505,243 at 4% or $336,828 at 6%; with 50% employer match about $336,828 at 4% or $224,552 at 6%; with 100% employer match about $252,621 at 4% or $168,414 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-20$636,509$404,194$20,210iApproximate average salary by contribution assumption: employee only about $505,243 at 4% or $336,828 at 6%; with 50% employer match about $336,828 at 4% or $224,552 at 6%; with 100% employer match about $252,621 at 4% or $168,414 at 6%.
201119$192,182$209,516$23,280iApproximate average salary by contribution assumption: employee only about $581,989 at 4% or $387,993 at 6%; with 50% employer match about $387,993 at 4% or $258,662 at 6%; with 100% employer match about $290,994 at 4% or $193,996 at 6%.
Karyopharm Therapeutics Inc. 401(K) Plan-9$192,182$209,516$23,280iApproximate average salary by contribution assumption: employee only about $581,989 at 4% or $387,993 at 6%; with 50% employer match about $387,993 at 4% or $258,662 at 6%; with 100% employer match about $290,994 at 4% or $193,996 at 6%.